gene_oid	gene_length	percent_identity	query_start	query_end	subj_start	subj_end	evalue	bit_score	cog_id	cog_name	cog_length
2852593896	417	99.05	2	417	2	418	0.0e+00	568.1	COG0766	UDP-N-acetylglucosamine enolpyruvyl transferase	421
2852593897	192	97.84	2	189	2	182	9.1e-68	223.9	COG2096	Cob(I)alamin adenosyltransferase	184
2852593899	121	82.96	1	121	1	112	6.4e-35	116.5	COG0355	FoF1-type ATP synthase, epsilon subunit	135
2852593900	501	98.93	15	482	2	464	0.0e+00	743.7	COG0055	FoF1-type ATP synthase, beta subunit	468
2852593901	308	99.65	6	303	1	287	1.4e-106	352.9	COG0224	FoF1-type ATP synthase, gamma subunit	287
2852593902	548	99.4	4	515	2	502	0.0e+00	767.6	COG0056	FoF1-type ATP synthase, alpha subunit	504
2852593903	445	28.09	191	259	23	72	3.4e-39	10.3	COG0712	FoF1-type ATP synthase, delta subunit	178
2852593903	445	95.03	1	157	7	159	9.7e-27	89.1	COG0711	FoF1-type ATP synthase, membrane subunit b or b'	161
2852593903	445	97.19	266	444	5	177	3.4e-39	118.6	COG0712	FoF1-type ATP synthase, delta subunit	178
2852593904	170	89.44	18	168	3	146	2.1e-29	98.6	COG0711	FoF1-type ATP synthase, membrane subunit b or b'	161
2852593905	81	91.25	1	79	7	79	1.7e-20	69.5	COG0636	FoF1-type ATP synthase, membrane subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K	79
2852593906	251	98.81	1	247	2	250	1.1e-71	237.8	COG0356	FoF1-type ATP synthase, membrane subunit a	246
2852593907	149	14.63	15	91	7	67	1.1e-01	6.7	COG1721	Uncharacterized conserved protein, DUF58 family, contains vWF domain	416
2852593907	149	16.31	78	148	6	73	1.1e-01	7.1	COG1721	Uncharacterized conserved protein, DUF58 family, contains vWF domain	416
2852593908	403	97.85	26	368	5	323	1.5e-76	254.3	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
2852593909	217	98.58	2	212	2	210	1.2e-67	223.6	COG0009	tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC	211
2852593910	278	98.61	1	278	1	283	2.6e-70	233.4	COG2890	Methylase of polypeptide chain release factors	280
2852593911	357	96.97	2	357	8	359	0.0e+00	485	COG0216	Protein chain release factor A	363
2852593912	78	96	1	73	1	72	5.5e-34	112.8	COG0254	Ribosomal protein L31	75
2852593913	201	92.34	2	200	10	202	1.6e-16	58	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852593914	613	97.87	31	606	8	420	0.0e+00	617.5	COG1158	Transcription termination factor Rho	422
2852593915	314	96.01	10	311	7	295	4.4e-84	278.4	COG0083	Homoserine kinase	299
2852593916	360	80.19	3	356	47	382	3.0e-124	411.4	COG0498	Threonine synthase	411
2852593917	441	99.1	5	331	2	332	7.7e-110	363.7	COG0460	Homoserine dehydrogenase	333
2852593918	473	98.99	39	449	5	395	3.4e-119	394.6	COG0019	Diaminopimelate decarboxylase	394
2852593919	550	99.83	4	550	2	581	0.0e+00	553.5	COG0018	Arginyl-tRNA synthetase	577
2852593922	647	88.78	3	324	27	303	1.5e-40	135.3	COG0501	Zn-dependent protease with chaperone function	302
2852593923	200	92.43	2	198	4	174	1.7e-59	196.8	COG1704	Uncharacterized conserved protein	185
2852593924	1417	52.85	241	532	37	249	3.1e-20	69.5	COG3391	DNA-binding beta-propeller fold protein YncE	381
2852593924	1417	80.15	491	938	37	359	3.1e-20	10.2	COG3391	DNA-binding beta-propeller fold protein YncE	381
2852593925	540	97.01	18	534	10	560	3.2e-87	289.5	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2852593926	256	88.39	24	238	9	206	3.6e-35	117.9	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
2852593927	422	73.03	90	410	79	300	2.2e-10	36.3	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
2852593928	1408	41.69	230	496	68	235	2.2e-21	65.6	COG3391	DNA-binding beta-propeller fold protein YncE	381
2852593928	1408	89.83	469	816	32	393	2.2e-21	23.3	COG3391	DNA-binding beta-propeller fold protein YncE	381
2852593931	360	97.81	4	324	2	314	1.3e-103	342.8	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2852593932	299	75.76	173	294	22	121	1.7e-24	82.1	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2852593934	296	97.01	3	296	2	293	4.2e-52	174.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
2852593935	365	99.7	1	359	1	330	8.3e-35	117.2	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2852593936	1421	45.16	96	540	76	257	3.9e-27	59.3	COG3391	DNA-binding beta-propeller fold protein YncE	381
2852593936	1421	85.11	483	836	20	362	3.9e-27	48.5	COG3391	DNA-binding beta-propeller fold protein YncE	381
2852593937	1387	35.24	915	1071	149	290	9.8e-29	7.8	COG3391	DNA-binding beta-propeller fold protein YncE	381
2852593937	1387	46.15	290	509	72	257	9.8e-29	68.6	COG3391	DNA-binding beta-propeller fold protein YncE	381
2852593937	1387	83.62	457	802	22	358	9.8e-29	44.5	COG3391	DNA-binding beta-propeller fold protein YncE	381
2852593939	294	87.46	4	293	19	318	1.1e-33	113.1	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852593941	137	97.26	7	135	3	144	1.5e-11	42	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2852593942	372	94.91	9	361	11	327	7.3e-48	159.5	COG1275	Tellurite resistance protein TehA and related permeases	329
2852593943	435	81.33	38	434	70	374	9.9e-46	153	COG4585	Signal transduction histidine kinase	365
2852593944	214	96.21	1	214	1	203	3.9e-41	137.5	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2852593946	320	87.1	1	188	15	176	3.2e-47	157.3	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2852593947	133	57.93	3	124	11	94	5.1e-10	35.9	COG3871	General stress protein 26 (function unknown)	145
2852593948	337	92.75	2	337	11	330	2.2e-69	230.8	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
2852593949	179	92.51	4	179	6	178	1.3e-32	110	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2852593950	130	98.63	4	122	3	146	6.0e-08	28.2	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2852593952	300	88.81	11	294	14	275	1.0e-13	48.1	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852593953	226	92.82	1	208	9	202	3.3e-11	40.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852593954	158	96	1	150	1	144	7.8e-42	139.3	COG1959	DNA-binding transcriptional regulator, IscR family	150
2852593955	198	89.32	18	189	5	188	1.0e-30	103.2	COG1335	Nicotinamidase-related amidase	205
2852593956	242	35.87	120	241	162	260	6.2e-48	73	COG1218	3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase	276
2852593956	242	43.12	4	125	12	130	6.2e-48	85.3	COG1218	3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase	276
2852593957	614	66.47	443	571	6	118	3.0e-07	26.2	COG0645	Predicted kinase	170
2852593957	614	97.93	1	436	5	429	0.0e+00	635.5	COG2895	Sulfate adenylyltransferase subunit 1, EFTu-like GTPase family	431
2852593958	307	94.4	2	307	16	268	4.9e-72	238.8	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
2852593959	374	93.2	1	367	12	340	1.0e-46	155.6	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
2852593960	143	53.62	1	40	1	37	8.8e-09	5.6	COG1942	Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family	69
2852593960	143	78.26	68	133	4	57	8.8e-09	23.9	COG1942	Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family	69
2852593961	189	88.52	2	188	13	197	2.5e-13	47	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852593962	268	93.64	1	268	9	273	1.5e-42	142.4	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2852593963	141	90.78	4	141	9	136	2.4e-27	91.8	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
2852593964	52	36.88	1	52	85	136	9.7e-09	31.7	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
2852593965	163	94.71	1	163	1	197	8.6e-36	118	COG0288	Carbonic anhydrase	207
2852593966	626	97.26	18	614	3	534	1.4e-58	195.6	COG1807	4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family	535
2852593967	419	93.53	283	417	8	137	3.1e-10	36.1	COG2246	Putative flippase GtrA (transmembrane translocase of bactoprenol-linked glucose)	139
2852593968	621	96.53	27	608	10	537	8.1e-55	183.1	COG1807	4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family	535
2852593969	540	82.99	140	533	62	388	4.1e-71	236.7	COG0642	Signal transduction histidine kinase	336
2852593970	252	98.71	27	252	2	230	6.7e-79	260.9	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2852593974	325	99.37	1	325	1	316	3.8e-96	318.7	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2852593975	315	95.3	15	309	13	296	2.1e-90	299.1	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2852593976	611	99.09	1	609	5	551	0.0e+00	681.8	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
2852593977	556	95.5	1	550	9	560	1.0e-59	199.4	COG0747	ABC-type transport system, periplasmic component	556
2852593978	418	91.86	26	362	6	276	1.3e-29	99.6	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852593979	404	95.99	2	398	12	394	8.0e-54	179.6	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852593980	307	99.67	1	302	1	299	4.1e-69	229.5	COG1732	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)	300
2852593981	242	87	10	225	25	218	7.7e-51	168.9	COG1174	ABC-type proline/glycine betaine transport system, permease component	221
2852593982	214	91.03	1	213	18	220	2.4e-48	161	COG1174	ABC-type proline/glycine betaine transport system, permease component	221
2852593983	367	99.36	1	357	1	312	1.5e-110	366	COG1125	ABC-type proline/glycine betaine transport system, ATPase component	309
2852593984	227	26.83	146	216	179	244	1.9e-45	36.9	COG1414	DNA-binding transcriptional regulator, IclR family	246
2852593984	227	58.13	7	152	2	144	1.9e-45	117.9	COG1414	DNA-binding transcriptional regulator, IclR family	246
2852593985	482	98.19	1	474	5	493	1.2e-75	246.3	COG2986	Histidine ammonia-lyase	498
2852593986	502	97.01	2	502	8	558	1.5e-123	408.9	COG2303	Choline dehydrogenase or related flavoprotein	542
2852593988	535	84.86	8	314	6	330	2.0e-31	106.3	COG0477	MFS family permease	338
2852593989	219	81.67	1	112	6	103	4.4e-25	83.9	COG1733	DNA-binding transcriptional regulator, HxlR family	120
2852593990	208	97.6	4	208	4	206	4.1e-37	124.5	COG5588	Uncharacterized protein	207
2852593991	258	72.79	5	251	75	280	8.9e-54	176.7	COG5486	Predicted metal-binding membrane protein	283
2852593993	382	99.5	1	380	1	402	9.9e-46	152.4	COG0420	DNA repair exonuclease SbcCD nuclease subunit	390
2852593994	168	98.77	5	168	2	162	1.7e-40	134.9	COG2062	Phosphohistidine phosphatase SixA	163
2852593997	560	95.61	1	554	25	590	0.0e+00	516.8	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2852593998	636	98.14	25	635	6	586	0.0e+00	605.8	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2852593999	721	94.57	1	721	44	809	4.1e-121	401.8	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2852594002	283	81.66	75	277	27	213	3.2e-36	120.9	COG2013	Uncharacterized conserved protein, AIM24 family	227
2852594003	149	99.31	7	149	1	144	1.8e-54	180.6	COG1490	D-Tyr-tRNAtyr deacylase	145
2852594004	206	91.96	5	206	13	195	1.6e-48	161.7	COG3544	Uncharacterized conserved protein, DUF305 family	190
2852594005	68	95.89	1	68	1	70	4.2e-16	55.7	COG2608	Copper chaperone CopZ	71
2852594007	729	99.32	1	728	3	728	0.0e+00	870.7	COG2217	Cation transport ATPase	713
2852594009	404	97.79	1	403	2	400	6.3e-48	159.3	COG1819	UDP:flavonoid glycosyltransferase YjiC, YdhE family	406
2852594010	375	37.3	34	151	9	99	9.9e-53	35.7	COG2114	Adenylate cyclase, class 3	227
2852594010	375	81.97	163	375	35	234	9.9e-53	143.9	COG2114	Adenylate cyclase, class 3	227
2852594011	164	94.67	8	164	1	160	1.6e-27	93.3	COG3663	G:T/U-mismatch repair DNA glycosylase	169
2852594012	459	99.38	3	457	3	480	2.7e-117	389.2	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
2852594013	277	72.73	126	276	28	123	4.1e-11	39	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2852594015	454	48.35	1	216	7	197	1.5e-27	54.6	COG2814	Predicted arabinose efflux permease, MFS family	394
2852594015	454	55.19	214	451	171	388	1.5e-27	44.3	COG2814	Predicted arabinose efflux permease, MFS family	394
2852594016	157	98.54	12	139	2	136	2.7e-26	88.8	COG2764	Uncharacterized conserved protein PhnB, glyoxalase superfamily	136
2852594017	145	97.16	1	143	1	137	1.1e-39	132.1	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
2852594019	349	90.67	8	328	9	319	2.9e-58	193.9	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852594020	272	98.51	41	270	2	200	1.7e-50	167.6	COG1573	Uracil-DNA glycosylase	202
2852594021	409	49.87	217	408	17	207	2.8e-21	41.3	COG0477	MFS family permease	338
2852594021	409	57.96	6	247	4	225	2.8e-21	36.6	COG0477	MFS family permease	338
2852594022	871	73.75	795	862	15	73	8.3e-16	52.3	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2852594023	454	98.51	4	454	2	463	6.2e-124	410.9	COG0277	FAD/FMN-containing dehydrogenase	459
2852594024	413	93.35	3	413	28	420	1.4e-100	333.6	COG2124	Cytochrome P450	411
2852594025	194	71.29	6	186	14	162	6.7e-21	72.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852594026	791	99.18	43	588	4	487	0.0e+00	469.8	COG3119	Arylsulfatase A or related enzyme	475
2852594027	237	91.35	7	237	16	258	1.2e-40	133.5	COG2375	NADPH-dependent ferric siderophore reductase, contains FAD-binding and SIP domains	265
2852594028	273	91.7	17	266	14	256	3.8e-29	97.9	COG2116	Formate/nitrite transporter FocA, FNT family	265
2852594029	383	89.2	15	383	11	357	6.1e-71	235.8	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
2852594030	562	94.42	2	513	27	517	0.0e+00	530.6	COG0513	Superfamily II DNA and RNA helicase	513
2852594033	1140	99.37	8	511	2	472	0.0e+00	453.3	COG2251	Predicted nuclease, RecB family	474
2852594034	449	99.15	6	449	2	466	4.7e-107	355.2	COG0277	FAD/FMN-containing dehydrogenase	459
2852594035	679	45.43	265	485	16	189	1.6e-44	17.4	COG0477	MFS family permease	338
2852594035	679	83.81	11	300	2	322	1.6e-44	135.7	COG0477	MFS family permease	338
2852594036	420	84.33	15	330	8	330	1.2e-28	95.1	COG0477	MFS family permease	338
2852594039	1236	39.11	1	379	339	699	0.0e+00	148.9	COG0567	2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes	906
2852594039	1236	93.28	349	1236	62	922	0.0e+00	1202.5	COG0567	2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes	906
2852594041	253	50.63	56	226	39	159	6.7e-19	64.1	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
2852594042	276	90.65	1	240	1	223	1.6e-53	178.3	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
2852594044	276	32.67	168	272	202	299	6.9e-14	25.3	COG1732	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)	300
2852594044	276	45.67	1	155	15	151	6.9e-14	21.2	COG1732	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)	300
2852594045	393	87.56	3	392	23	409	0.0e+00	445.5	COG0281	Malic enzyme	432
2852594046	329	98.73	6	329	2	312	4.8e-82	272.1	COG0039	Malate/lactate dehydrogenase	313
2852594047	354	92.68	23	354	25	328	3.7e-77	255.8	COG0598	Mg2+ and Co2+ transporter CorA	322
2852594049	410	99.71	1	378	1	349	0.0e+00	483.6	COG3839	ABC-type sugar transport system, ATPase component	338
2852594050	279	95.76	1	278	13	283	2.1e-79	263.5	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
2852594051	308	96.64	17	303	5	292	3.1e-80	266.1	COG1175	ABC-type sugar transport system, permease component	295
2852594052	465	97.74	2	462	5	437	4.8e-76	253.3	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2852594056	302	95.09	1	294	12	282	6.5e-68	225.5	COG2301	Citrate lyase beta subunit	283
2852594057	431	39.65	1	184	22	201	1.4e-63	50.3	COG2239	Mg/Co/Ni transporter MgtE (contains CBS domain)	451
2852594057	431	51.1	166	420	21	252	1.4e-63	161.8	COG2239	Mg/Co/Ni transporter MgtE (contains CBS domain)	451
2852594058	183	83.25	1	181	20	178	2.8e-53	177	COG4420	Uncharacterized membrane protein	191
2852594059	444	68.88	38	327	75	313	3.1e-43	144.3	COG2951	Membrane-bound lytic murein transglycosylase B	343
2852594060	380	96.85	35	335	6	282	7.4e-78	257.7	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
2852594061	130	97.87	1	103	1	92	2.7e-15	53.1	COG1826	Sec-independent protein translocase protein TatA	94
2852594062	497	92.88	142	497	24	362	9.0e-91	301.1	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2852594064	248	90.86	67	243	11	179	3.0e-56	186.1	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2852594065	221	96.36	11	221	7	218	2.0e-61	203.6	COG4122	Predicted O-methyltransferase YrrM	219
2852594066	228	91.39	1	193	15	205	1.6e-14	51.2	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852594067	310	98.04	15	307	4	303	7.4e-81	268.4	COG1131	ABC-type multidrug transport system, ATPase component	293
2852594068	540	99.25	18	540	2	533	1.6e-98	327.2	COG3559	Putative exporter of polyketide antibiotics	536
2852594069	224	97.88	36	224	3	187	2.4e-32	109	COG2020	Protein-S-isoprenylcysteine O-methyltransferase Ste14	187
2852594070	224	97.88	36	224	3	187	1.8e-39	132.3	COG2020	Protein-S-isoprenylcysteine O-methyltransferase Ste14	187
2852594072	282	85.48	2	164	19	177	6.8e-32	107.3	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2852594073	314	99.7	1	311	1	330	2.6e-74	246.7	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2852594077	188	87.56	1	187	7	189	1.9e-13	48.2	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852594078	162	87.97	11	148	14	130	6.8e-18	60.6	COG1846	DNA-binding transcriptional regulator, MarR family	126
2852594079	404	97.19	3	404	5	385	0.0e+00	499.7	COG0448	ADP-glucose pyrophosphorylase	393
2852594080	387	97.56	2	387	7	405	4.6e-47	157.9	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2852594082	200	96.81	8	198	2	183	5.5e-76	250.7	COG2818	3-methyladenine DNA glycosylase Tag	188
2852594084	502	79.51	261	453	46	239	2.0e-36	121.5	COG2114	Adenylate cyclase, class 3	227
2852594085	316	29.25	40	304	4	108	3.4e-15	53.7	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2852594086	304	95.68	20	299	8	273	5.3e-84	278.1	COG0294	Dihydropteroate synthase	274
2852594087	603	97.89	39	565	6	561	3.0e-82	273.1	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2852594088	186	85.85	3	185	17	192	8.7e-53	175.3	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
2852594089	689	55.98	254	686	62	267	4.4e-04	13.9	COG0457	Tetratricopeptide (TPR) repeat	291
2852594092	536	94.77	1	535	3	509	7.0e-118	391.2	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
2852594093	355	96.89	1	355	9	413	1.1e-58	195.8	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2852594094	314	94.85	40	314	14	271	4.8e-90	298.3	COG2171	Tetrahydrodipicolinate N-succinyltransferase	271
2852594095	427	98.04	3	427	3	402	6.3e-51	170.2	COG1819	UDP:flavonoid glycosyltransferase YjiC, YdhE family	406
2852594096	397	96.77	78	384	5	304	2.6e-38	128.1	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
2852594097	392	95.19	14	392	14	389	3.0e-78	259.6	COG2814	Predicted arabinose efflux permease, MFS family	394
2852594098	185	5.69	152	175	187	198	2.9e-03	2.8	COG2173	D-alanyl-D-alanine dipeptidase	211
2852594098	185	41.23	51	157	65	151	2.9e-03	10.5	COG2173	D-alanyl-D-alanine dipeptidase	211
2852594099	116	88.98	1	116	13	125	1.2e-03	15	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
2852594100	472	88.73	19	471	52	555	3.0e-88	289.4	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2852594101	178	68.6	25	176	31	148	4.2e-14	49.3	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2852594102	257	99.25	7	255	2	267	1.0e-68	228.3	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852594103	139	94.66	7	133	7	130	1.2e-30	102.5	COG1917	Cupin domain protein related to quercetin dioxygenase	131
2852594104	373	96.75	52	373	10	307	1.5e-46	155.1	COG1073	Fermentation-respiration switch protein FrsA, has esterase activity, DUF1100 family	299
2852594105	341	100	1	341	1	353	2.8e-81	269.5	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
2852594106	292	35.38	18	118	14	59	9.0e-05	19.4	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2852594109	131	90.51	1	130	6	129	1.7e-24	82.9	COG4319	Ketosteroid isomerase homolog	137
2852594110	320	83.87	2	319	2	339	2.6e-64	214.3	COG0506	Proline dehydrogenase	391
2852594111	546	98.96	42	535	3	476	1.9e-110	366.1	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2852594112	526	95.32	66	526	15	421	4.2e-52	172.6	COG2508	DNA-binding transcriptional regulator, PucR family	421
2852594114	288	44.7	21	122	1	59	9.2e-12	41.6	COG0789	DNA-binding transcriptional regulator, MerR family	124
2852594115	196	91.4	8	186	3	172	1.6e-53	177.6	COG1443	Isopentenyldiphosphate isomerase	185
2852594119	507	98.21	25	494	2	496	1.4e-31	104.8	COG3349	Uncharacterized conserved protein, contains NAD-binding domain and a Fe-S cluster	485
2852594120	236	89.54	4	235	13	226	1.4e-27	92.8	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
2852594122	114	17.86	6	113	242	316	1.4e-02	11.1	COG1668	ABC-type Na+ efflux pump, permease component	407
2852594123	316	94.46	12	307	8	280	4.0e-64	213.1	COG1562	Phytoene/squalene synthetase	288
2852594124	514	97.99	16	504	5	491	2.4e-90	300.4	COG1233	Phytoene dehydrogenase-related protein	487
2852594125	370	89.63	47	370	34	327	2.5e-58	193.6	COG0142	Geranylgeranyl pyrophosphate synthase	322
2852594127	331	89.65	1	331	35	389	5.3e-73	242.3	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
2852594128	108	89.04	2	65	8	72	1.4e-16	56.7	COG1146	NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit	68
2852594130	186	62.04	2	143	9	93	5.8e-24	80.7	COG1695	DNA-binding transcriptional regulator, PadR family	138
2852594131	669	98.9	1	354	3	361	1.5e-108	359.5	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
2852594132	133	70.9	20	124	30	124	2.3e-11	40.5	COG4113	Predicted nucleic acid-binding protein, contains PIN domain	134
2852594133	187	86.53	1	182	22	188	5.2e-56	185.8	COG2353	Polyisoprenoid-binding periplasmic protein YceI	192
2852594134	153	31.68	72	141	16	66	5.0e-03	11.6	COG3402	Uncharacterized membrane protein YdbS, contains bPH2 (bacterial pleckstrin homology) domain	161
2852594134	153	37.27	3	79	26	85	5.0e-03	7.9	COG3402	Uncharacterized membrane protein YdbS, contains bPH2 (bacterial pleckstrin homology) domain	161
2852594136	859	92.78	495	859	20	366	0.0e+00	355.1	COG1060	2-iminoacetate synthase ThiH (tyrosine cleavage enzyme, thamine biosynthesis)	370
2852594136	859	98.4	28	409	4	371	0.0e+00	287.5	COG1060	2-iminoacetate synthase ThiH (tyrosine cleavage enzyme, thamine biosynthesis)	370
2852594140	294	97.97	1	290	6	246	3.0e-68	226.7	COG2120	N-acetylglucosaminyl deacetylase, LmbE family	237
2852594142	411	89.89	1	410	15	414	2.0e-50	168.3	COG0038	H+/Cl- antiporter ClcA	443
2852594144	525	88.32	31	402	19	313	2.4e-46	155.1	COG1316	Anionic cell wall polymer biosynthesis enzyme,  LytR-Cps2A-Psr (LCP) family	307
2852594145	629	95.33	4	617	11	561	1.6e-40	135.8	COG0747	ABC-type transport system, periplasmic component	556
2852594146	629	99.17	1	625	4	601	0.0e+00	892.6	COG1217	Predicted membrane GTPase involved in stress response	603
2852594147	85	44.78	20	67	15	44	2.3e-03	13.5	COG2051	Ribosomal protein S27E	67
2852594149	135	70.93	4	134	22	143	2.6e-18	62.5	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2852594150	95	92.08	1	94	4	96	6.4e-30	99.6	COG2154	Pterin-4a-carbinolamine dehydratase	101
2852594156	48	45.76	3	43	14	40	1.1e-02	12.7	COG5466	Predicted small metal-binding protein	59
2852594157	221	98.15	1	214	3	214	1.1e-24	82.5	COG0778	Nitroreductase	207
2852594158	129	55.75	4	129	4	129	1.4e-23	80.2	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
2852594159	192	51.66	1	144	23	131	8.9e-09	31.2	COG0177	Endonuclease III	211
2852594160	116	95.1	13	113	5	101	8.6e-32	105.7	COG3162	Uncharacterized membrane protein, DUF485 family	102
2852594161	547	98.88	11	539	6	535	0.0e+00	544.1	COG4147	Na+(or H+)/acetate symporter ActP	529
2852594162	398	51.96	2	207	8	206	5.5e-23	69	COG0477	MFS family permease	338
2852594162	398	51.96	195	396	5	203	5.5e-23	15.2	COG0477	MFS family permease	338
2852594164	190	90.91	1	190	14	203	1.9e-16	57.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852594166	888	77.87	2	173	53	242	1.7e-34	116.1	COG2114	Adenylate cyclase, class 3	227
2852594166	888	92.75	191	603	2	385	9.5e-87	287.2	COG3903	Predicted ATPase	414
2852594167	402	97.35	48	401	3	369	1.5e-93	310.2	COG4833	Predicted alpha-1,6-mannanase, GH76 family	377
2852594168	203	95.19	2	203	9	206	7.4e-52	172	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2852594170	147	56.02	3	140	14	106	1.4e-05	21.8	COG3467	Nitroimidazol reductase NimA or a related FMN-containing flavoprotein, pyridoxamine 5'-phosphate oxidase superfamily	166
2852594171	172	96.63	1	172	1	172	8.2e-47	156	COG3797	Uncharacterized conserved protein, DUF1697 family	178
2852594172	279	85.33	8	278	10	265	1.2e-48	162.3	COG3315	O-Methyltransferase involved in polyketide biosynthesis	297
2852594173	508	98.65	2	458	7	446	0.0e+00	439	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
2852594174	400	99.3	1	400	1	424	4.8e-70	233.4	COG2508	DNA-binding transcriptional regulator, PucR family	421
2852594175	121	94.4	7	121	1	118	4.7e-32	107.2	COG1725	DNA-binding transcriptional regulator YhcF, GntR family	125
2852594176	237	93.39	1	236	14	253	1.6e-77	256.5	COG0846	NAD-dependent protein deacetylase, SIR2 family	250
2852594177	210	48.03	5	206	47	180	2.2e-11	41	COG0500	SAM-dependent methyltransferase	257
2852594178	246	93.78	4	231	5	200	3.9e-23	79.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852594179	758	80.25	1	755	8	763	0.0e+00	485.6	COG2409	Uncharacterized membrane protein YdfJ, MMPL/SSD domain	937
2852594182	331	98.26	1	321	3	341	6.8e-82	272.1	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
2852594183	250	98.13	2	246	4	266	2.5e-51	171.2	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852594184	364	94.76	1	364	6	385	7.2e-111	367.5	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2852594185	273	97.74	12	270	7	265	9.9e-70	231.4	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2852594187	426	50.65	233	423	2	195	4.9e-15	22.8	COG0477	MFS family permease	338
2852594187	426	53.79	17	236	6	211	4.9e-15	35.7	COG0477	MFS family permease	338
2852594188	239	92.61	30	239	12	224	9.2e-20	67.9	COG1266	Membrane protease YdiL, CAAX protease family	226
2852594189	377	83.33	2	273	4	233	3.0e-35	118.1	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
2852594190	203	92.34	1	199	11	203	9.9e-12	42.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852594191	343	98.12	1	324	2	315	8.8e-99	326.9	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2852594192	174	93.22	3	174	6	170	6.9e-58	191.5	COG0663	Carbonic anhydrase or acetyltransferase, isoleucine patch superfamily	176
2852594193	318	95.08	1	318	9	317	2.2e-81	269.9	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
2852594194	439	23.5	336	437	8	97	3.6e-20	14.7	COG0477	MFS family permease	338
2852594194	439	94.26	27	343	5	365	3.6e-20	60.1	COG0477	MFS family permease	338
2852594195	244	67.8	57	211	63	201	2.1e-19	66.5	COG2335	Uncaracterized surface protein containing fasciclin (FAS1) repeats	187
2852594196	380	96.99	3	380	7	393	1.9e-118	392.5	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852594197	265	97.74	5	262	7	265	1.2e-74	247.4	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2852594198	381	99.49	1	381	1	392	9.0e-125	413.3	COG0183	Acetyl-CoA acetyltransferase	392
2852594199	263	95.85	18	258	6	236	7.2e-46	152.8	COG2186	DNA-binding transcriptional regulator, FadR family	241
2852594201	233	89.49	2	233	27	290	4.7e-10	35.9	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852594203	177	90.28	1	139	13	142	1.8e-31	105.8	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
2852594204	254	99.25	6	253	2	267	1.3e-61	205	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852594205	201	83.25	1	200	8	181	1.1e-16	58.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852594206	107	83.33	1	107	7	106	4.9e-43	142.2	COG1733	DNA-binding transcriptional regulator, HxlR family	120
2852594207	203	95.26	1	197	2	202	1.2e-46	155.1	COG2085	Predicted dinucleotide-binding enzyme	211
2852594209	266	95.09	5	263	7	258	1.4e-71	237	COG0300	Short-chain dehydrogenase	265
2852594210	298	98.31	4	298	4	293	1.0e-31	107.3	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852594213	500	99.19	2	385	3	369	6.2e-76	252.3	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852594214	384	95.14	2	372	1	352	7.6e-78	258.6	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852594215	439	93.78	3	364	16	362	5.0e-80	265.6	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852594216	444	92.7	1	352	11	353	1.0e-73	245	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852594217	343	92.43	1	343	6	347	9.9e-81	268.3	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852594218	483	97.57	5	346	10	370	6.9e-72	239	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852594219	284	93.26	5	278	17	265	1.1e-75	250.4	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
2852594220	255	92.51	2	255	19	265	5.1e-79	261.7	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
2852594221	157	98.68	1	148	3	151	9.3e-49	161.9	COG3865	Glyoxalase superfamily enzyme, possibly 3-demethylubiquinone-9 3-methyltransferase	151
2852594222	203	77.51	14	203	35	196	2.1e-18	64.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852594223	284	94.92	5	284	14	293	2.7e-37	125.5	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852594224	964	90.45	12	346	9	311	1.3e-62	207.4	COG2334	Ser/Thr protein kinase RdoA involved in Cpx stress response, MazF antagonist	331
2852594224	964	95.29	533	964	20	444	7.1e-120	396.8	COG0160	4-aminobutyrate aminotransferase or related aminotransferase	447
2852594226	124	90.77	1	124	7	124	1.9e-26	89.2	COG4308	Limonene-1,2-epoxide hydrolase	130
2852594228	260	87.7	62	260	17	230	9.5e-41	136.5	COG2114	Adenylate cyclase, class 3	227
2852594235	388	85.4	2	384	35	379	7.4e-51	170	COG1680	CubicO group peptidase, beta-lactamase class C family	390
2852594236	248	72.04	2	235	45	245	5.8e-19	65.4	COG0500	SAM-dependent methyltransferase	257
2852594238	261	51.61	3	253	44	187	8.2e-21	71.4	COG0500	SAM-dependent methyltransferase	257
2852594240	359	99.46	1	359	3	372	0.0e+00	453.6	COG0012	Ribosome-binding ATPase YchF, GTP1/OBG family	372
2852594244	306	90.07	47	304	13	257	4.7e-32	107.6	COG0631	Serine/threonine protein phosphatase PrpC	262
2852594245	736	46.6	112	441	3	221	1.9e-33	112.7	COG0515	Serine/threonine protein kinase	384
2852594247	321	95.05	2	317	11	279	1.9e-54	181.3	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2852594250	333	97.29	22	315	3	289	1.3e-119	395	COG0761	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH	294
2852594252	409	18.2	324	409	361	441	1.6e-121	43.8	COG1570	Exonuclease VII, large subunit	440
2852594252	409	75.51	9	351	2	337	1.6e-121	364.6	COG1570	Exonuclease VII, large subunit	440
2852594253	70	83.95	1	70	4	71	1.8e-24	81.9	COG1722	Exonuclease VII small subunit	81
2852594254	370	97.82	8	349	3	316	8.0e-63	209.2	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2852594256	235	26.1	121	234	203	279	3.3e-20	16.8	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852594256	235	41.36	3	131	2	123	3.3e-20	58.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852594257	514	92.21	2	465	3	452	1.7e-102	340.8	COG3119	Arylsulfatase A or related enzyme	475
2852594258	300	55.86	34	200	5	128	7.6e-05	18.1	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
2852594259	292	78.98	2	292	69	331	8.6e-73	242	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
2852594261	258	98.13	2	242	4	266	1.1e-65	218.4	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852594262	276	79.85	1	269	1	214	1.0e-50	169.4	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852594263	391	94.44	1	362	10	349	1.5e-55	185.1	COG0628	Predicted PurR-regulated permease PerM	355
2852594264	275	90.72	21	275	21	235	4.9e-20	68.3	COG0412	Dienelactone hydrolase	236
2852594266	342	99.1	9	329	2	331	0.0e+00	474.1	COG1494	Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase or related protein	332
2852594267	474	99.35	11	470	2	460	0.0e+00	682.2	COG0114	Fumarate hydratase class II	462
2852594268	914	77.5	836	906	9	70	3.2e-16	54.3	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2852594269	917	6.26	837	913	826	881	1.6e-16	33.8	COG2909	ATP-, maltotriose- and DNA-dependent transcriptional regulator MalT	894
2852594269	917	24.05	573	837	550	764	1.6e-16	7.7	COG2909	ATP-, maltotriose- and DNA-dependent transcriptional regulator MalT	894
2852594269	917	31.21	245	584	266	544	1.6e-16	16.9	COG2909	ATP-, maltotriose- and DNA-dependent transcriptional regulator MalT	894
2852594272	405	92.89	3	404	8	412	7.4e-62	205.5	COG0025	NhaP-type Na+/H+ or K+/H+ antiporter	429
2852594273	293	76.12	3	241	59	262	8.4e-52	172.5	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
2852594275	376	98.21	5	293	2	276	1.2e-77	257.6	COG3629	DNA-binding transcriptional activator of the SARP family	280
2852594277	469	66.81	4	346	2	315	1.1e-60	202.4	COG0515	Serine/threonine protein kinase	384
2852594279	437	99.77	5	428	2	440	0.0e+00	573.9	COG1875	Predicted ribonuclease YlaK, contains NYN-type RNase and PhoH-family ATPase domains	436
2852594282	488	93.49	26	484	7	394	0.0e+00	517.3	COG0112	Glycine/serine hydroxymethyltransferase	413
2852594284	312	99.65	5	287	2	282	5.4e-114	376.4	COG1072	Panthothenate kinase	283
2852594288	263	96.43	7	263	9	251	9.1e-89	293.6	COG0020	Undecaprenyl pyrophosphate synthase	245
2852594289	245	88.46	17	245	25	231	7.2e-62	205.1	COG1272	Predicted membrane channel-forming protein YqfA, hemolysin III family	226
2852594290	123	63.69	1	118	37	136	8.2e-05	18.6	COG4875	Uncharacterized protein	156
2852594291	661	98.67	2	661	6	673	0.0e+00	749.9	COG1331	Uncharacterized conserved protein YyaL, SSP411 family, contains thoiredoxin and six-hairpin glycosidase-like domains	667
2852594293	299	97.56	4	294	6	245	1.0e-68	228.1	COG2120	N-acetylglucosaminyl deacetylase, LmbE family	237
2852594295	164	99.34	9	162	1	151	3.2e-42	140.6	COG0782	Transcription elongation factor, GreA/GreB family	151
2852594297	384	98.24	2	384	5	394	0.0e+00	489.3	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
2852594298	388	98.25	7	388	5	396	5.5e-98	325.1	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852594299	368	91.7	47	346	21	285	1.1e-33	113	COG5473	Uncharacterized membrane protein	290
2852594300	183	84.66	4	182	5	153	1.2e-09	34.2	COG1714	Uncharacterized membrane protein YckC, RDD family	172
2852594301	220	50.57	5	218	62	150	3.8e-05	17.9	COG1714	Uncharacterized membrane protein YckC, RDD family	172
2852594302	464	59.89	320	460	73	184	2.8e-18	62.3	COG3620	Predicted transcriptional regulator with C-terminal CBS domains	187
2852594302	464	99.34	3	304	3	302	3.5e-112	370.7	COG0031	Cysteine synthase	300
2852594303	271	77.99	3	271	68	315	4.8e-53	177.3	COG0657	Acetyl esterase/lipase	312
2852594304	321	92.31	61	274	14	217	1.5e-13	47.4	COG2755	Lysophospholipase L1 or related esterase	216
2852594305	405	99.75	1	404	1	393	0.0e+00	435.6	COG0183	Acetyl-CoA acetyltransferase	392
2852594306	282	99.28	1	281	2	275	2.1e-115	381.5	COG4760	Uncharacterized membrane protein, YccA/Bax inhibitor family	276
2852594307	345	99.25	1	318	3	265	8.2e-77	254.4	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2852594308	259	100	1	256	1	265	9.2e-89	293.8	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2852594309	564	94.39	1	564	29	583	0.0e+00	762.9	COG4425	Uncharacterized membrane protein	588
2852594310	123	80.7	13	121	16	107	7.6e-13	44.8	COG0607	Rhodanese-related sulfurtransferase	110
2852594314	320	92.48	1	319	8	302	4.3e-77	256.1	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
2852594315	285	60.5	1	278	13	205	8.1e-34	114.1	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
2852594316	239	48.38	45	229	77	210	7.9e-10	34.2	COG2503	Predicted secreted acid phosphatase	274
2852594317	286	98.83	1	259	1	253	1.7e-51	171.7	COG0121	Predicted glutamine amidotransferase	252
2852594318	347	96.48	2	347	3	331	1.7e-79	263.8	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
2852594319	247	98.88	2	245	3	267	3.8e-56	187.1	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852594320	348	55.5	14	159	69	184	2.2e-32	54	COG2140	Oxalate decarboxylase/archaeal phosphoglucose isomerase, cupin superfamily	209
2852594320	348	57.89	179	338	81	201	2.2e-32	52.7	COG2140	Oxalate decarboxylase/archaeal phosphoglucose isomerase, cupin superfamily	209
2852594321	350	99.71	1	349	1	349	1.6e-120	398.7	COG3804	Uncharacterized protein	350
2852594322	373	98.21	3	287	2	276	4.3e-85	282	COG3629	DNA-binding transcriptional activator of the SARP family	280
2852594324	396	99.49	2	394	2	393	1.7e-82	274.1	COG0183	Acetyl-CoA acetyltransferase	392
2852594327	460	97.13	15	437	4	409	0.0e+00	469.8	COG1301	Na+/H+-dicarboxylate symporter	415
2852594328	204	42.86	36	184	63	128	3.1e-03	12.2	COG3354	Archaellum component FlaG, FlaF/FlaG flagellin family	154
2852594329	521	95.72	5	520	5	518	4.7e-111	368.1	COG3290	Sensor histidine kinase regulating citrate/malate metabolism	537
2852594330	229	98.21	2	229	1	220	2.9e-55	183.7	COG4565	Response regulator of citrate/malate metabolism	224
2852594331	316	11.96	3	47	155	190	6.6e-31	7.6	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2852594331	316	86.71	38	298	39	299	6.6e-31	103	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2852594332	349	93.35	3	347	23	359	2.8e-52	174.2	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
2852594333	335	25.06	197	316	94	194	9.5e-21	35.9	COG3391	DNA-binding beta-propeller fold protein YncE	381
2852594333	335	46.4	27	215	47	233	9.5e-21	41.1	COG3391	DNA-binding beta-propeller fold protein YncE	381
2852594334	137	52.59	35	130	40	100	6.7e-16	54.6	COG3339	Uncharacterized membrane protein YkvA, DUF1232 family	116
2852594337	260	45.45	2	98	13	72	2.0e-57	30.7	COG2343	Uncharacterized conserved protein, DUF427 family	132
2852594337	260	95.45	119	252	2	127	2.0e-57	156.6	COG2343	Uncharacterized conserved protein, DUF427 family	132
2852594338	320	92.9	2	317	22	322	3.4e-86	285.9	COG0627	S-formylglutathione hydrolase FrmB	316
2852594341	140	35.34	2	140	48	182	3.4e-21	71.8	COG3448	CBS-domain-containing membrane protein	382
2852594342	271	98.51	2	269	3	266	2.7e-60	200.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852594344	211	68.9	1	211	12	155	3.1e-14	50.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852594345	417	86.7	8	409	55	419	3.1e-90	299.6	COG2124	Cytochrome P450	411
2852594348	80	38.57	5	59	41	67	6.8e-03	12.7	COG3311	Predicted DNA-binding transcriptional regulator AlpA	70
2852594350	559	98.57	7	559	6	557	0.0e+00	689.7	COG2060	K+-transporting ATPase, A chain	560
2852594351	716	98.68	17	715	7	679	0.0e+00	1066	COG2216	High-affinity K+ transport system, ATPase chain B	681
2852594352	289	40.21	201	285	113	188	3.9e-53	98.1	COG2156	K+-transporting ATPase, c chain	190
2852594352	289	47.62	6	131	3	92	3.9e-53	76.7	COG2156	K+-transporting ATPase, c chain	190
2852594353	839	33.67	533	839	588	889	0.0e+00	277.5	COG2205	K+-sensing histidine kinase KdpD	890
2852594353	839	59.87	2	538	17	553	0.0e+00	669.4	COG2205	K+-sensing histidine kinase KdpD	890
2852594354	230	98.71	6	230	2	230	3.4e-75	248.8	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2852594356	511	16.46	434	507	171	209	2.4e-20	25.5	COG0775	Nucleoside phosphorylase	234
2852594356	511	41.35	209	333	7	104	2.4e-20	42.5	COG0775	Nucleoside phosphorylase	234
2852594357	530	97.99	3	512	3	489	4.1e-97	322.6	COG1233	Phytoene dehydrogenase-related protein	487
2852594359	264	94.34	1	260	4	253	9.7e-58	191.9	COG0300	Short-chain dehydrogenase	265
2852594360	288	98.31	13	286	3	292	2.1e-35	119.3	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852594361	623	98.91	45	607	1	546	0.0e+00	683.7	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2852594362	262	86.94	11	262	7	259	1.4e-31	106.6	COG3327	DNA-binding transcriptional regulator PaaX (phenylacetic acid degradation)	291
2852594363	387	82.45	32	384	32	341	2.8e-37	124.9	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
2852594364	272	98.87	1	259	1	262	6.1e-69	228.7	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2852594366	54	37.01	1	50	77	123	1.3e-02	12.4	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
2852594367	61	35.43	1	54	70	114	1.9e-02	10.3	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
2852594369	246	97.08	1	223	7	239	5.6e-80	258	COG4312	Predicted dithiol-disulfide oxidoreductase, DUF899 family	247
2852594370	312	61.82	1	312	3	308	1.5e-93	310.7	COG0248	Exopolyphosphatase/pppGpp-phosphohydrolase	492
2852594371	163	96.41	1	163	2	162	2.9e-79	261.1	COG1507	Uncharacterized protein	167
2852594372	208	78.81	43	160	23	115	5.6e-20	67.7	COG2919	Cell division protein FtsB	117
2852594373	429	98.82	1	424	3	422	0.0e+00	646.2	COG0148	Enolase	423
2852594374	242	72.33	1	242	32	282	9.7e-46	153.1	COG2951	Membrane-bound lytic murein transglycosylase B	343
2852594375	304	79.22	19	291	8	331	1.1e-29	98.4	COG0672	High-affinity Fe2+/Pb2+ permease	383
2852594376	385	95.71	5	383	16	372	5.1e-98	325.3	COG2822	Iron uptake system EfeUOB, periplasmic (or lipoprotein) component EfeO/EfeM	376
2852594377	430	93.99	44	430	20	363	3.4e-80	266.3	COG2837	Periplasmic deferrochelatase/peroxidase EfeB	352
2852594378	373	94.17	83	184	4	100	1.3e-25	83.8	COG1694	NTP pyrophosphatase, house-cleaning of non-canonical NTPs	102
2852594379	1218	97.02	29	1199	22	1127	0.0e+00	1283.2	COG1197	Transcription-repair coupling factor (superfamily II helicase)	1139
2852594380	214	93.78	4	208	7	202	2.7e-27	93.2	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852594382	491	98.91	6	469	3	456	0.0e+00	599	COG1207	Bifunctional protein GlmU, N-acetylglucosamine-1-phosphate-uridyltransferase/glucosamine-1-phosphate-acetyltransferase	460
2852594383	326	99.37	7	323	3	318	3.6e-119	394.2	COG0462	Phosphoribosylpyrophosphate synthetase	314
2852594384	117	94.87	6	117	5	115	1.9e-36	121.2	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
2852594386	698	71.27	44	273	64	254	6.6e-34	113.4	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
2852594386	698	81.39	282	694	9	419	3.3e-70	233.4	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
2852594388	289	78.73	10	257	2	212	1.8e-41	139	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852594389	222	98.92	7	99	2	93	1.6e-32	106.4	COG1825	Ribosomal protein L25 (general stress protein Ctc)	93
2852594390	192	98.41	3	192	3	188	7.6e-68	224.3	COG0193	Peptidyl-tRNA hydrolase	190
2852594391	344	32.93	188	311	81	135	6.1e-08	28.2	COG1142	Fe-S-cluster-containing hydrogenase component 2	165
2852594393	241	97.39	2	227	7	267	1.4e-53	176.8	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852594394	146	98.63	2	143	2	145	1.9e-13	48.4	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2852594395	496	97.98	1	446	5	441	5.0e-100	332.4	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
2852594396	261	91.86	1	254	24	294	1.1e-26	90.8	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852594398	417	95.49	10	408	19	420	7.3e-101	334.5	COG2124	Cytochrome P450	411
2852594399	318	79.26	1	303	64	361	5.5e-29	97.7	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
2852594400	334	98.13	17	273	6	268	2.8e-52	174.1	COG1018	Ferredoxin-NADP reductase	266
2852594402	461	91.02	1	440	41	476	7.2e-112	370.8	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2852594403	263	98.88	2	252	3	267	1.3e-41	139.2	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852594404	512	95.25	3	511	19	559	6.1e-97	321.5	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2852594405	423	63.23	26	421	155	424	7.4e-26	87.2	COG2508	DNA-binding transcriptional regulator, PucR family	421
2852594409	217	96.17	15	216	4	204	1.8e-19	67.5	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852594410	775	83.7	60	770	128	805	0.0e+00	638.2	COG2937	Glycerol-3-phosphate O-acyltransferase	810
2852594411	384	98.25	1	383	3	394	1.8e-127	422.3	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852594413	214	96.17	9	214	4	204	2.5e-21	73.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852594414	383	99.75	1	383	1	393	8.8e-119	393.6	COG0183	Acetyl-CoA acetyltransferase	392
2852594415	380	96.74	3	380	7	392	2.2e-111	369.2	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852594416	530	28.17	90	224	114	242	3.2e-50	86.8	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
2852594416	530	72.27	219	530	125	455	3.2e-50	91.1	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
2852594416	530	97.26	1	70	1	71	1.1e-11	40.1	COG1146	NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit	68
2852594417	49	70.59	1	46	20	67	2.5e-08	30.7	COG1141	Ferredoxin	68
2852594418	462	92.07	1	441	36	476	3.0e-111	368.7	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2852594419	263	99.25	2	252	2	267	9.6e-43	142.8	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852594420	419	96.67	6	419	13	419	1.6e-87	290.6	COG2124	Cytochrome P450	411
2852594421	512	95.42	2	511	19	560	3.5e-94	312.5	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2852594422	133	59.7	14	117	40	119	1.6e-04	18.5	COG3255	Putative sterol carrier protein	134
2852594423	90	14.42	1	88	62	136	1.6e-02	10.5	COG0815	Apolipoprotein N-acyltransferase	518
2852594424	217	85.92	18	217	28	210	1.8e-39	131.7	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
2852594426	367	89.8	5	353	17	324	1.5e-34	115.8	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852594427	365	62.68	29	316	46	265	1.9e-07	25.9	COG3178	Predicted phosphotransferase, aminoglycoside/choline kinase (APH/ChoK) family	351
2852594428	307	88.27	12	307	34	319	2.0e-63	211.1	COG0627	S-formylglutathione hydrolase FrmB	316
2852594429	161	45.12	7	159	104	200	7.7e-06	22.4	COG2340	Uncharacterized conserved protein YkwD, contains CAP (CSP/antigen 5/PR1) domain	207
2852594432	486	97.84	3	372	8	369	6.1e-78	258.8	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852594433	306	79.19	1	303	69	361	7.3e-53	176.5	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852594434	433	97.84	1	367	2	363	1.7e-78	260.8	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852594435	450	98.11	1	354	4	366	2.4e-78	260.2	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852594436	342	91.35	2	342	11	348	1.1e-75	251.6	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852594437	486	99.46	6	349	3	370	2.0e-77	257.3	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852594438	264	88.76	1	258	29	265	4.9e-71	235.6	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
2852594439	255	92.13	2	255	20	265	3.5e-79	262.2	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
2852594440	437	97.99	4	432	3	489	1.9e-36	109.5	COG1233	Phytoene dehydrogenase-related protein	487
2852594441	385	98.25	2	385	7	398	3.7e-92	305.9	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852594442	403	98.11	140	400	6	265	1.4e-62	207.8	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2852594443	150	88.05	2	150	17	156	6.4e-38	126	COG2030	Acyl dehydratase	159
2852594445	356	91.13	20	340	11	308	1.2e-59	198.5	COG3173	Predicted  kinase, aminoglycoside phosphotransferase (APT) family	321
2852594446	333	93.08	7	293	9	250	2.0e-36	121.6	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2852594447	517	92.96	2	516	34	561	9.0e-111	367.3	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2852594448	532	96.13	15	530	12	557	1.7e-114	379.5	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2852594449	286	98.13	3	247	4	266	1.8e-45	151.9	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852594450	350	89.8	4	342	19	326	1.4e-43	145.5	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852594451	457	76.91	1	344	6	348	9.2e-68	221.9	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
2852594452	206	77.03	1	204	10	170	1.5e-14	51.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852594453	307	19.83	217	295	153	199	2.1e-12	9.3	COG0412	Dienelactone hydrolase	236
2852594453	307	53.16	2	171	22	147	2.1e-12	34.5	COG0412	Dienelactone hydrolase	236
2852594454	346	97.95	1	346	4	337	2.2e-77	256.8	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
2852594455	247	93.66	1	229	17	267	1.5e-62	208	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852594459	401	98.22	7	392	2	388	1.2e-67	225.1	COG0183	Acetyl-CoA acetyltransferase	392
2852594460	456	77.3	329	448	28	136	4.4e-22	74	COG1545	Uncharacterized OB-fold protein, contains Zn-ribbon domain	140
2852594460	456	80.83	7	324	34	345	5.7e-36	120.5	COG3425	3-hydroxy-3-methylglutaryl CoA synthase	377
2852594461	403	99.24	1	401	2	392	1.0e-116	386.8	COG0183	Acetyl-CoA acetyltransferase	392
2852594463	173	87.8	13	164	8	151	1.4e-27	93	COG5517	3-phenylpropionate/cinnamic acid dioxygenase, small subunit	164
2852594464	422	89.36	21	390	8	343	1.2e-53	178.9	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
2852594465	261	98.11	1	253	6	265	4.4e-69	229.3	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2852594466	266	99.25	3	263	3	265	9.4e-67	221.7	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2852594467	251	89.06	1	249	6	241	5.0e-64	212.7	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2852594468	244	98.88	4	243	3	267	1.2e-70	234.6	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852594469	265	98.88	3	263	3	267	2.4e-56	187.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852594470	391	98.5	4	388	3	395	1.4e-93	310.5	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852594471	212	94.74	9	211	7	204	3.4e-24	83	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852594473	505	97.18	2	504	6	557	4.6e-100	332.5	COG2303	Choline dehydrogenase or related flavoprotein	542
2852594476	302	97.72	2	302	3	302	1.9e-47	158.3	COG0492	Thioredoxin reductase	305
2852594477	1000	98.3	9	951	4	929	0.0e+00	932.3	COG2409	Uncharacterized membrane protein YdfJ, MMPL/SSD domain	937
2852594480	552	97.72	232	543	6	305	2.0e-68	226.9	COG0492	Thioredoxin reductase	305
2852594481	294	97.29	22	294	5	291	6.8e-29	97.9	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852594483	188	88.04	3	187	12	195	1.7e-14	51.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852594484	282	57.32	8	188	42	178	1.0e-23	80	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
2852594485	282	79.18	30	281	55	286	3.4e-12	42.5	COG0842	ABC-type multidrug transport system, permease component	286
2852594486	317	99.35	1	308	2	305	7.8e-90	297.9	COG1131	ABC-type multidrug transport system, ATPase component	293
2852594488	555	91.85	47	543	36	542	1.6e-49	164.5	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2852594489	343	90.24	62	338	24	282	3.5e-106	351	COG2876	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase	286
2852594490	658	8.6	493	577	366	406	1.2e-12	5.2	COG4529	Uncharacterized NAD(P)/FAD-binding protein YdhS	474
2852594490	658	49.69	5	297	3	239	1.2e-12	36.3	COG4529	Uncharacterized NAD(P)/FAD-binding protein YdhS	474
2852594491	463	97.04	10	453	12	437	1.2e-94	313.9	COG0015	Adenylosuccinate lyase	438
2852594492	372	99.3	46	356	2	284	7.3e-73	242.4	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
2852594493	204	19.7	1	52	7	46	1.1e-05	11	COG3917	2-hydroxychromene-2-carboxylate isomerase	203
2852594493	204	34.98	61	164	119	189	1.1e-05	8.9	COG3917	2-hydroxychromene-2-carboxylate isomerase	203
2852594494	421	90.89	7	420	9	417	9.7e-40	133.4	COG0439	Biotin carboxylase	449
2852594495	424	62.44	13	334	40	320	4.0e-24	81.7	COG0439	Biotin carboxylase	449
2852594497	423	45.95	223	419	12	187	1.2e-18	24	COG0477	MFS family permease	338
2852594497	423	57.7	3	248	16	236	1.2e-18	43.1	COG0477	MFS family permease	338
2852594499	224	97.72	1	222	4	217	2.1e-41	138.1	COG1878	Kynurenine formamidase	218
2852594500	393	86.01	7	284	24	275	1.4e-33	112.3	COG2006	Uncharacterized conserved protein, DUF362 family	293
2852594501	457	78.37	29	455	95	460	6.2e-117	388.1	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
2852594502	200	97.91	1	188	3	189	6.2e-75	247.4	COG0512	Anthranilate/para-aminobenzoate synthase component II	191
2852594503	280	79.18	2	257	9	221	1.2e-55	185.2	COG1606	ATP-utilizing enzyme, PP-loop superfamily	269
2852594504	226	85.43	6	225	31	247	7.7e-79	261	COG1691	NCAIR mutase (PurE)-related protein	254
2852594505	414	97.7	7	396	3	385	1.5e-123	409.1	COG1641	Uncharacterized conserved protein, DUF111 family	387
2852594506	544	90.49	9	541	39	552	6.6e-80	265.1	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2852594507	324	94.83	15	321	3	277	4.4e-87	288.3	COG1947	4-diphosphocytidyl-2C-methyl-D-erythritol kinase	289
2852594508	265	63.4	9	264	2	299	7.3e-41	137.3	COG0515	Serine/threonine protein kinase	384
2852594509	250	76.92	1	216	55	254	4.3e-54	179.9	COG0030	16S rRNA A1518 and A1519 N6-dimethyltransferase RsmA/KsgA/DIM1 (may also have DNA glycosylase/AP lyase activity)	259
2852594510	362	95.79	1	296	14	309	5.1e-102	337.5	COG3583	Uncharacterized conserved protein YabE, contains G5 and tandem DUF348 domains	309
2852594511	280	99.22	15	275	2	256	7.5e-71	234.9	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
2852594512	514	97.5	1	514	4	548	0.0e+00	628.2	COG0143	Methionyl-tRNA synthetase	558
2852594513	433	95.92	16	419	14	342	1.1e-71	238.1	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852594514	433	94.75	16	419	18	342	8.9e-70	231.8	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852594515	379	97.04	13	215	6	202	7.7e-73	240.2	COG0108	3,4-dihydroxy-2-butanone 4-phosphate synthase	203
2852594516	368	86.16	1	355	45	374	1.5e-09	30.7	COG0477	MFS family permease	338
2852594517	493	34.18	11	176	255	389	2.5e-07	12.3	COG2814	Predicted arabinose efflux permease, MFS family	394
2852594517	493	48.35	190	400	15	205	2.5e-07	20.1	COG2814	Predicted arabinose efflux permease, MFS family	394
2852594518	331	99.06	1	331	1	315	5.7e-88	291.9	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2852594519	292	89.6	13	292	27	293	9.9e-77	254.3	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2852594520	438	96.21	13	424	11	340	4.1e-68	226.5	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852594521	649	14.15	344	411	15	60	0.0e+00	32.8	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
2852594521	649	73.23	404	639	86	323	0.0e+00	214.1	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
2852594521	649	94.15	8	316	3	308	0.0e+00	341	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
2852594522	161	77.72	1	161	4	146	2.2e-16	56.5	COG0431	NAD(P)H-dependent FMN reductase	184
2852594523	180	85.41	14	180	13	170	1.6e-33	112.4	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
2852594525	541	96.89	20	539	12	571	8.0e-75	248.9	COG0747	ABC-type transport system, periplasmic component	556
2852594526	437	94.75	18	423	18	342	2.0e-70	234	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852594527	393	94.88	5	374	3	391	2.4e-64	213.8	COG1252	NADH dehydrogenase, FAD-containing subunit	405
2852594528	298	30.15	170	290	8	48	7.8e-04	14.4	COG3631	Ketosteroid isomerase-related protein	133
2852594528	298	88.17	2	169	15	178	4.4e-30	100.9	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2852594529	414	77.52	46	409	101	462	1.1e-92	308	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
2852594531	278	99.26	1	277	2	271	8.7e-86	283.9	COG0313	16S rRNA C1402 (ribose-2'-O) methylase RsmI	275
2852594532	516	3.56	320	346	369	393	3.9e-111	2.3	COG1928	Dolichyl-phosphate-mannose--protein O-mannosyl transferase	699
2852594532	516	25.93	333	516	516	697	3.9e-111	140.9	COG1928	Dolichyl-phosphate-mannose--protein O-mannosyl transferase	699
2852594532	516	44.16	7	333	21	330	3.9e-111	227.7	COG1928	Dolichyl-phosphate-mannose--protein O-mannosyl transferase	699
2852594534	400	99.26	1	400	4	407	0.0e+00	451.3	COG2235	Arginine deiminase	409
2852594535	144	93.94	7	123	2	125	5.5e-26	87.8	COG0789	DNA-binding transcriptional regulator, MerR family	124
2852594536	198	99	6	190	3	200	7.7e-36	120.4	COG3145	Alkylated DNA repair dioxygenase AlkB	194
2852594544	272	97.18	4	271	3	278	1.3e-71	237.4	COG0169	Shikimate 5-dehydrogenase	283
2852594545	332	59.17	11	200	7	135	1.1e-19	67.1	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2852594547	579	97.01	1	579	11	561	6.7e-119	394.3	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2852594548	414	97.79	1	412	2	400	3.5e-98	326	COG1819	UDP:flavonoid glycosyltransferase YjiC, YdhE family	406
2852594549	1107	91.04	264	641	21	396	1.3e-40	136.4	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
2852594551	423	98.53	1	416	2	403	2.2e-99	330	COG1819	UDP:flavonoid glycosyltransferase YjiC, YdhE family	406
2852594552	1040	99.47	10	1015	4	940	0.0e+00	919.6	COG2409	Uncharacterized membrane protein YdfJ, MMPL/SSD domain	937
2852594554	2093	15.59	1201	1983	940	1124	0.0e+00	16.4	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
2852594554	2093	75.31	2013	2088	10	70	6.5e-05	18.3	COG0236	Acyl carrier protein	80
2852594554	2093	99.33	2	1200	7	1185	0.0e+00	1342.5	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
2852594556	345	42.74	237	310	68	117	1.8e-02	5.1	COG3462	Uncharacterized membrane protein	117
2852594556	345	47.86	7	76	50	105	1.8e-02	3.2	COG3462	Uncharacterized membrane protein	117
2852594557	217	90.91	20	202	13	182	7.9e-39	130	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2852594558	421	98.03	1	421	7	405	0.0e+00	443.8	COG0303	Molybdopterin biosynthesis enzyme	404
2852594559	303	97.24	7	300	5	286	7.7e-100	330	COG1210	UTP-glucose-1-phosphate uridylyltransferase	291
2852594560	201	96.34	3	192	4	187	1.3e-42	142.5	COG0212	5-formyltetrahydrofolate cyclo-ligase	191
2852594562	217	68.84	14	216	27	216	6.5e-09	31.7	COG3745	Flp pilus assembly protein CpaB	276
2852594564	152	97.71	1	124	3	130	4.0e-37	124.1	COG1970	Large-conductance mechanosensitive channel	130
2852594567	164	92.35	3	164	9	165	3.4e-44	146.8	COG0521	Molybdopterin biosynthesis enzyme MoaB	169
2852594568	448	91.78	77	448	24	358	1.7e-88	293.6	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2852594569	491	84.77	42	476	56	389	4.8e-62	207.2	COG0642	Signal transduction histidine kinase	336
2852594570	228	98.71	1	227	2	230	1.8e-87	289	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2852594571	57	47.37	1	43	1	27	4.3e-06	23.3	COG0333	Ribosomal protein L32	57
2852594573	386	96.99	3	386	7	393	2.2e-108	359.3	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852594574	531	99.43	12	531	4	526	0.0e+00	587.6	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component	526
2852594575	645	99.85	1	639	1	645	0.0e+00	683	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
2852594576	386	98.5	2	386	6	398	8.7e-93	308	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852594577	255	97.74	1	253	7	265	1.1e-58	195.3	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2852594578	253	85.14	3	246	2	236	3.5e-37	124.8	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
2852594581	658	98.93	2	657	8	652	0.0e+00	1167.5	COG4867	Uncharacterized protein, contains von Willebrand factor type A (vWA) domain	652
2852594582	460	99.53	19	460	2	422	3.7e-118	391.7	COG1239	Mg-chelatase subunit ChlI	423
2852594584	522	99.81	8	522	2	515	0.0e+00	681.3	COG0138	AICAR transformylase/IMP cyclohydrolase PurH	515
2852594585	209	96.5	13	208	2	194	8.1e-65	214.6	COG0299	Folate-dependent phosphoribosylglycinamide formyltransferase PurN	200
2852594588	376	96.79	15	364	7	338	1.2e-69	231.5	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852594589	373	95.95	1	373	16	394	6.3e-79	262	COG0019	Diaminopimelate decarboxylase	394
2852594591	282	60.93	8	279	16	224	2.3e-60	200.4	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852594592	509	73.1	1	416	13	300	9.9e-21	69	COG0183	Acetyl-CoA acetyltransferase	392
2852594593	300	98.98	1	300	1	291	1.5e-117	388.6	COG0074	Succinyl-CoA synthetase, alpha subunit	293
2852594594	391	99.48	1	390	1	381	0.0e+00	488.1	COG0045	Succinyl-CoA synthetase, beta subunit	387
2852594597	770	98.66	17	688	2	663	0.0e+00	770.4	COG0210	Superfamily I DNA or RNA helicase	655
2852594598	87	61.39	3	81	6	67	1.1e-15	54.1	COG1605	Chorismate mutase	101
2852594599	641	97.17	1	385	11	388	3.6e-97	322.2	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
2852594600	482	98.33	12	482	3	473	0.0e+00	540.4	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2852594601	555	99.56	47	541	3	453	0.0e+00	623.7	COG0166	Glucose-6-phosphate isomerase	446
2852594603	249	94.34	1	249	6	255	4.8e-50	166.7	COG0300	Short-chain dehydrogenase	265
2852594604	1060	55.43	463	981	136	339	1.2e-03	14.8	COG0457	Tetratricopeptide (TPR) repeat	291
2852594604	1060	77.46	16	234	46	234	4.0e-42	141	COG2114	Adenylate cyclase, class 3	227
2852594605	287	100	1	272	1	274	6.9e-56	186.4	COG0266	Formamidopyrimidine-DNA glycosylase	273
2852594606	133	96.67	1	131	1	116	2.1e-38	127.7	COG1950	Uncharacterized membrane protein YvlD, DUF360 family	120
2852594607	247	97.87	2	247	2	231	3.8e-45	150.8	COG2243	Precorrin-2 methylase	234
2852594610	403	44.91	206	399	25	196	1.9e-20	31.7	COG0477	MFS family permease	338
2852594610	403	55.35	2	235	4	215	1.9e-20	42.8	COG0477	MFS family permease	338
2852594612	288	64.14	2	239	12	231	6.2e-52	173.1	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852594614	252	87.18	6	121	12	113	3.0e-04	16.1	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
2852594615	613	84.54	421	505	3	84	1.9e-03	7.7	COG4842	Uncharacterized conserved protein YukE	97
2852594615	613	99.26	7	272	1	268	7.8e-79	259.4	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
2852594617	333	75.76	207	333	22	121	2.1e-20	68.8	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2852594618	253	99.25	7	252	2	267	1.2e-71	237.9	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852594619	137	84.62	1	136	2	133	5.7e-37	123.2	COG1720	tRNA (Thr-GGU) A37 N-methylase	156
2852594621	205	45.02	7	175	81	175	7.3e-14	48.6	COG1716	Forkhead associated (FHA) domain, binds pSer, pThr, pTyr	191
2852594622	993	8.92	842	891	324	357	2.4e-17	2.1	COG3055	N-acetylneuraminic acid mutarotase	381
2852594622	993	9.19	889	944	327	361	2.4e-17	3.7	COG3055	N-acetylneuraminic acid mutarotase	381
2852594622	993	9.97	747	796	323	360	2.4e-17	5.2	COG3055	N-acetylneuraminic acid mutarotase	381
2852594622	993	10.24	935	982	322	360	2.4e-17	2.4	COG3055	N-acetylneuraminic acid mutarotase	381
2852594622	993	11.29	641	704	322	364	2.4e-17	2.5	COG3055	N-acetylneuraminic acid mutarotase	381
2852594622	993	11.55	787	845	319	362	2.4e-17	15.9	COG3055	N-acetylneuraminic acid mutarotase	381
2852594622	993	12.07	567	642	112	157	2.4e-17	3.3	COG3055	N-acetylneuraminic acid mutarotase	381
2852594622	993	12.6	494	565	320	367	2.4e-17	8.2	COG3055	N-acetylneuraminic acid mutarotase	381
2852594622	993	16.8	411	500	83	146	2.4e-17	4.2	COG3055	N-acetylneuraminic acid mutarotase	381
2852594622	993	67.02	13	398	9	323	7.2e-47	156.7	COG0515	Serine/threonine protein kinase	384
2852594623	762	11.99	366	448	2	60	1.1e-97	23.1	COG1793	ATP-dependent DNA ligase	444
2852594623	762	67.28	435	762	145	475	1.1e-97	299.6	COG1793	ATP-dependent DNA ligase	444
2852594623	762	94.7	3	309	8	293	2.2e-100	331.6	COG3285	Eukaryotic-type DNA primase	299
2852594626	419	57.56	63	229	48	165	3.8e-03	12.6	COG3642	tRNA A-37 threonylcarbamoyl transferase component Bud32	204
2852594627	359	99.43	1	353	1	348	0.0e+00	440.2	COG3839	ABC-type sugar transport system, ATPase component	338
2852594628	293	94.35	21	293	17	283	4.0e-69	229.6	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
2852594629	324	92.95	29	321	16	292	2.7e-82	272.9	COG1175	ABC-type sugar transport system, permease component	295
2852594630	454	96.61	5	449	10	437	2.6e-70	234.4	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2852594631	345	96.56	21	345	10	318	1.8e-74	247	COG2390	DNA-binding transcriptional regulator LsrR, DeoR family	321
2852594632	344	99.15	12	343	1	350	2.1e-90	299.5	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
2852594633	471	99.16	9	466	4	473	0.0e+00	459	COG0246	Mannitol-1-phosphate/altronate dehydrogenases	473
2852594634	322	94.62	9	313	3	301	2.7e-46	154.5	COG0524	Sugar or nucleoside kinase, ribokinase family	311
2852594635	309	98.21	1	285	4	277	6.6e-100	330.5	COG1273	Non-homologous end joining protein Ku, dsDNA break repair	278
2852594636	155	14.81	44	153	104	175	3.6e-10	35.6	COG0364	Glucose-6-phosphate 1-dehydrogenase	483
2852594637	263	99.25	6	255	2	267	6.5e-62	206	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852594638	358	99.43	1	357	1	348	0.0e+00	453.3	COG3804	Uncharacterized protein	350
2852594641	408	96.9	2	408	10	416	2.4e-122	405.1	COG1914	Mn2+ and Fe2+ transporters of the NRAMP family	416
2852594642	150	87.94	1	133	14	137	1.3e-27	92.7	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
2852594643	356	40.83	8	120	50	98	9.1e-06	19.5	COG2105	Uncharacterized conserved protein YtfP, gamma-glutamylcyclotransferase (GGCT)/AIG2-like family	120
2852594643	356	97.63	141	352	4	209	9.4e-55	181.4	COG4195	Phage-related replication protein YjqB, UPF0714/DUF867 family	208
2852594644	361	75	3	344	34	336	3.5e-51	171.1	COG1680	CubicO group peptidase, beta-lactamase class C family	390
2852594645	448	93.7	5	447	9	469	1.3e-61	205.1	COG0531	Amino acid transporter	466
2852594646	527	98.13	2	526	10	534	1.3e-124	413	COG1574	Predicted amidohydrolase YtcJ	535
2852594647	263	94.64	3	249	6	252	6.6e-66	218.1	COG3496	Uncharacterized conserved protein, DUF1365 family	261
2852594648	181	94.09	4	181	4	178	3.6e-35	117.9	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2852594649	237	88.75	5	235	16	228	3.3e-05	18.5	COG5343	Anti-sigma-K factor RskA	240
2852594650	363	94.85	3	362	2	351	3.2e-65	217.1	COG2170	Gamma-glutamyl:cysteine ligase YbdK, ATP-grasp superfamily	369
2852594651	273	90.67	6	273	18	328	1.7e-32	102.3	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852594655	295	91.05	1	294	28	322	5.7e-92	305	COG0627	S-formylglutathione hydrolase FrmB	316
2852594657	651	7.39	152	287	5	46	8.6e-42	42.9	COG2303	Choline dehydrogenase or related flavoprotein	542
2852594657	651	18.49	480	651	453	557	8.6e-42	72.6	COG2303	Choline dehydrogenase or related flavoprotein	542
2852594657	651	20.6	282	423	185	301	8.6e-42	28	COG2303	Choline dehydrogenase or related flavoprotein	542
2852594659	228	53.68	9	206	6	180	4.8e-08	29.2	COG2203	GAF domain	175
2852594660	403	98.22	3	401	3	389	1.6e-65	218.1	COG0183	Acetyl-CoA acetyltransferase	392
2852594661	503	98.98	1	487	3	487	0.0e+00	605.7	COG3670	Carotenoid cleavage dioxygenase or a related enzyme	490
2852594662	296	85.83	158	271	15	117	4.5e-39	35.8	COG1733	DNA-binding transcriptional regulator, HxlR family	120
2852594662	296	90	2	115	11	118	4.5e-39	91	COG1733	DNA-binding transcriptional regulator, HxlR family	120
2852594663	117	69.86	1	101	44	145	3.7e-29	97.9	COG0071	Molecular chaperone IbpA, HSP20 family	146
2852594664	198	90.91	7	187	17	186	2.7e-20	69.7	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2852594666	267	85.76	2	250	24	276	8.2e-17	58.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852594667	148	84.76	1	148	7	145	6.0e-39	130.2	COG3542	Predicted sugar epimerase, cupin superfamily	162
2852594668	242	11.41	197	242	243	276	1.3e-37	31.1	COG3246	Uncharacterized conserved protein, DUF849 family	298
2852594668	242	59.4	3	196	4	180	1.3e-37	94	COG3246	Uncharacterized conserved protein, DUF849 family	298
2852594669	573	10.31	227	277	126	148	7.8e-27	6.9	COG1226	Voltage-gated potassium channel Kch	212
2852594669	573	18.83	1	89	91	132	7.8e-27	25.3	COG1226	Voltage-gated potassium channel Kch	212
2852594669	573	49.33	319	458	20	129	7.8e-27	56.7	COG1226	Voltage-gated potassium channel Kch	212
2852594670	42	28.35	1	41	89	124	5.5e-07	26.6	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
2852594671	298	95.07	5	298	14	302	3.6e-63	210.3	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
2852594672	474	98.33	5	473	2	472	0.0e+00	529.6	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2852594673	568	97.12	5	561	8	546	3.0e-111	368.9	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
2852594674	315	32.83	2	142	10	140	2.3e-43	41.7	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852594674	315	37.09	156	315	244	391	2.3e-43	109	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852594675	390	96.99	2	387	11	397	7.5e-79	261.6	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852594677	385	98.75	3	385	1	394	1.2e-71	238.3	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852594678	387	96.26	1	386	7	392	1.7e-110	366.1	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2852594679	295	96.64	4	242	3	261	3.8e-47	157.4	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852594680	619	95.96	61	561	5	432	7.3e-76	250.4	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
2852594681	450	52.39	9	279	4	200	6.0e-41	137.1	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
2852594682	284	99.25	7	260	2	267	1.7e-58	194.8	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852594683	534	18.12	371	440	142	197	1.3e-23	13.6	COG3386	Sugar lactone lactonase YvrE	307
2852594683	534	18.45	416	531	140	196	1.3e-23	8.7	COG3386	Sugar lactone lactonase YvrE	307
2852594683	534	27.51	7	131	161	245	1.3e-23	19	COG3386	Sugar lactone lactonase YvrE	307
2852594683	534	44.34	122	264	139	275	1.3e-23	40.8	COG3386	Sugar lactone lactonase YvrE	307
2852594684	245	96.23	1	240	8	237	6.7e-44	146.7	COG2188	DNA-binding transcriptional regulator, GntR family	236
2852594685	518	96.83	14	516	9	558	1.3e-95	317.2	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2852594686	258	98.13	1	245	5	267	2.1e-67	224	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852594687	491	96.65	1	491	12	560	3.2e-110	365.7	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2852594688	217	72.46	1	207	1	200	5.3e-15	51.4	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
2852594689	199	93.78	4	199	6	201	1.2e-18	65.2	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852594691	199	77.03	3	197	7	167	5.0e-18	63	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852594694	261	69.09	1	256	26	253	3.2e-38	128.2	COG0714	MoxR-like ATPase	329
2852594695	42	39.06	1	34	34	58	2.1e-02	11.6	COG4068	Predicted nucleic acid-binding protein, contains Zn-ribbon domain	64
2852594698	148	54.78	2	120	10	95	1.0e-02	12	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
2852594700	793	89.44	1	788	55	918	7.9e-129	420.8	COG0474	Magnesium-transporting ATPase (P-type)	917
2852594701	524	86.88	3	446	30	380	7.3e-62	206.2	COG1680	CubicO group peptidase, beta-lactamase class C family	390
2852594702	370	97.74	98	368	3	261	5.5e-63	209.1	COG2220	L-ascorbate metabolism protein UlaG, beta-lactamase superfamily	258
2852594703	244	97.74	1	241	7	265	7.7e-54	179.3	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2852594704	323	94.14	5	323	18	322	3.3e-92	305.7	COG0627	S-formylglutathione hydrolase FrmB	316
2852594705	489	78.23	1	234	56	285	4.9e-83	267.4	COG0777	Acetyl-CoA carboxylase beta subunit	294
2852594706	232	60	1	231	24	200	2.1e-05	20.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852594708	265	8.48	3	48	15	38	9.3e-61	2.6	COG5486	Predicted metal-binding membrane protein	283
2852594708	265	72.08	42	255	75	278	9.3e-61	202.3	COG5486	Predicted metal-binding membrane protein	283
2852594709	205	95.67	1	204	5	203	6.2e-43	143.5	COG5588	Uncharacterized protein	207
2852594710	291	93.85	1	291	18	307	1.0e-35	119.8	COG3386	Sugar lactone lactonase YvrE	307
2852594714	181	54.07	1	180	11	123	1.0e-16	58.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852594715	379	99.49	2	378	2	392	6.4e-78	259.4	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2852594717	135	55	60	132	36	90	2.8e-03	14.2	COG0713	NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K)	100
2852594718	644	97.09	1	638	17	651	0.0e+00	673.5	COG3733	Cu2+-containing amine oxidase	654
2852594719	483	92.89	15	480	10	466	5.0e-43	143.7	COG0531	Amino acid transporter	466
2852594720	500	98.54	22	500	2	473	0.0e+00	570.6	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2852594721	482	93.29	6	467	11	469	1.4e-44	148.8	COG0531	Amino acid transporter	466
2852594722	238	98.78	14	238	2	244	2.0e-29	97.5	COG1414	DNA-binding transcriptional regulator, IclR family	246
2852594723	537	96.3	8	536	12	558	2.8e-130	431.7	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2852594724	563	98.01	32	554	5	545	0.0e+00	458.9	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2852594725	278	85	197	277	12	79	8.6e-20	66.1	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2852594726	138	84.93	1	128	22	145	1.6e-27	92.5	COG0071	Molecular chaperone IbpA, HSP20 family	146
2852594728	369	91.86	35	368	23	293	6.0e-22	75	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852594730	607	98.48	28	605	6	588	0.0e+00	548.7	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2852594731	642	98.48	26	601	4	586	0.0e+00	435	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2852594732	630	99.49	28	620	3	591	0.0e+00	524.2	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2852594733	189	88.83	6	189	4	178	4.8e-31	104.4	COG2059	Chromate transport protein ChrA	195
2852594734	187	88.83	8	187	5	179	7.0e-34	113.8	COG2059	Chromate transport protein ChrA	195
2852594735	329	30.93	4	163	293	442	6.5e-34	40.1	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
2852594735	329	32.99	154	325	287	446	6.5e-34	73	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
2852594736	233	98.71	8	233	2	230	3.9e-81	268.3	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2852594737	446	84.26	50	446	56	387	1.2e-47	159.9	COG0642	Signal transduction histidine kinase	336
2852594738	120	50.97	2	120	100	204	3.7e-37	124.9	COG0545	FKBP-type peptidyl-prolyl cis-trans isomerase	205
2852594740	505	96.98	1	505	7	488	1.2e-84	281.6	COG1233	Phytoene dehydrogenase-related protein	487
2852594741	1045	81.97	2	228	39	238	5.9e-45	150.3	COG2114	Adenylate cyclase, class 3	227
2852594742	139	86.47	11	139	15	129	1.6e-18	63.4	COG1846	DNA-binding transcriptional regulator, MarR family	126
2852594743	486	50.39	267	480	12	204	2.0e-44	22.6	COG0477	MFS family permease	338
2852594743	486	80.42	11	305	6	313	2.0e-44	129	COG0477	MFS family permease	338
2852594744	435	97.98	33	435	7	394	0.0e+00	524.7	COG0372	Citrate synthase	390
2852594745	216	84.69	8	213	8	184	1.8e-19	67.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852594746	425	47.78	216	422	8	190	7.0e-14	10	COG0477	MFS family permease	338
2852594746	425	59.53	8	241	5	232	7.0e-14	41.7	COG0477	MFS family permease	338
2852594747	229	98.13	5	229	5	214	1.2e-78	259.9	COG0259	Pyridoxine/pyridoxamine 5'-phosphate oxidase	214
2852594748	375	95.71	1	369	15	393	4.7e-99	321.8	COG0372	Citrate synthase	390
2852594750	149	98.54	8	138	2	136	3.8e-40	133.7	COG2764	Uncharacterized conserved protein PhnB, glyoxalase superfamily	136
2852594751	864	98.49	362	854	3	458	1.6e-90	300.4	COG2723	Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase	460
2852594752	100	59.79	27	98	6	63	1.0e-09	34.9	COG2314	Uncharacterized membrane protein YozV, TM2 domain	95
2852594753	1006	50	488	662	27	85	3.1e-03	13.3	COG0640	DNA-binding transcriptional regulator, ArsR family	110
2852594753	1006	78.21	8	286	19	237	9.8e-32	106.5	COG3629	DNA-binding transcriptional activator of the SARP family	280
2852594756	551	25.11	99	229	125	239	1.8e-61	77	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
2852594756	551	75.55	210	535	109	454	1.8e-61	134.8	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
2852594756	551	89.04	1	71	4	68	9.7e-13	43.7	COG1146	NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit	68
2852594758	173	55.81	2	168	82	201	7.6e-26	87.8	COG2340	Uncharacterized conserved protein YkwD, contains CAP (CSP/antigen 5/PR1) domain	207
2852594759	370	98.65	9	370	4	368	5.3e-97	321.4	COG1932	Phosphoserine aminotransferase	365
2852594761	267	27.41	3	118	15	108	4.2e-09	18.6	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852594761	267	42.27	117	263	172	316	4.2e-09	18.8	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852594763	271	96.96	7	270	4	258	7.4e-54	179.3	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
2852594764	143	84.96	9	137	16	128	5.1e-20	68.3	COG1846	DNA-binding transcriptional regulator, MarR family	126
2852594766	150	93.63	1	150	10	156	9.6e-06	21.5	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
2852594771	334	93.79	2	307	20	321	4.5e-116	383.8	COG0435	Glutathionyl-hydroquinone reductase	324
2852594772	136	95.52	1	65	3	66	2.2e-23	78.1	COG1278	Cold shock protein, CspA family	67
2852594773	134	92.41	1	134	1	134	4.0e-52	172.5	COG3304	Uncharacterized membrane protein YccF, DUF307 family	145
2852594774	350	99.69	23	350	2	325	2.9e-108	358.1	COG2896	Molybdenum cofactor biosynthesis enzyme MoaA	322
2852594775	84	100	4	84	1	84	1.0e-13	48.4	COG1977	Molybdopterin converting factor, small subunit	84
2852594778	142	91.28	3	142	4	139	2.0e-43	144.3	COG0314	Molybdopterin synthase catalytic subunit	149
2852594779	159	92.35	2	159	11	167	1.6e-44	147.8	COG0521	Molybdopterin biosynthesis enzyme MoaB	169
2852594780	159	97.44	5	159	3	154	2.7e-62	205.7	COG0315	Molybdenum cofactor biosynthesis enzyme	157
2852594783	477	48.46	50	264	17	173	6.2e-41	51.2	COG0627	S-formylglutathione hydrolase FrmB	316
2852594783	477	58.33	261	456	135	323	6.2e-41	89.8	COG0627	S-formylglutathione hydrolase FrmB	316
2852594784	549	83.57	145	544	2	408	3.3e-119	395.4	COG1061	Superfamily II DNA or RNA helicase	442
2852594785	121	95.89	7	116	7	146	1.9e-09	35.2	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2852594787	114	68.7	2	114	30	119	2.2e-15	53.2	COG1917	Cupin domain protein related to quercetin dioxygenase	131
2852594788	275	92.75	4	260	2	257	8.5e-33	109.8	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
2852594790	392	49.35	190	385	7	195	3.4e-08	6.4	COG0477	MFS family permease	338
2852594790	392	53	1	220	8	210	3.4e-08	25.5	COG0477	MFS family permease	338
2852594791	313	97.34	1	289	2	294	1.8e-36	120.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
2852594792	237	99.63	1	235	1	267	2.2e-50	168.2	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852594793	118	71.34	1	118	40	151	2.6e-04	16.2	COG4875	Uncharacterized protein	156
2852594797	329	89.5	6	328	17	323	7.3e-53	176.3	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852594798	62	10.19	1	57	1	49	4.9e-05	19.1	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
2852594799	454	94.29	23	454	20	432	4.2e-42	139.9	COG1541	Phenylacetate-coenzyme A ligase PaaK, adenylate-forming domain family	438
2852594801	141	50.6	2	126	11	94	8.5e-05	19.1	COG3467	Nitroimidazol reductase NimA or a related FMN-containing flavoprotein, pyridoxamine 5'-phosphate oxidase superfamily	166
2852594802	128	29.71	1	96	88	158	1.5e-02	10.9	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
2852594803	496	94.01	3	493	17	550	5.6e-54	172.4	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2852594805	510	35.93	217	444	23	128	1.1e-06	25.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852594806	181	62.2	2	179	13	142	2.8e-22	76.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852594807	402	95.67	1	402	3	378	4.6e-46	154.5	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2852594808	715	99.09	318	658	2	327	1.6e-104	345.9	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
2852594808	715	99.25	1	299	3	265	1.3e-61	203.7	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2852594809	403	99.75	2	403	2	394	2.4e-128	425.1	COG0183	Acetyl-CoA acetyltransferase	392
2852594810	391	97.22	2	390	7	391	3.3e-110	365.1	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
2852594811	303	88.34	3	299	16	318	3.4e-39	131.3	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852594812	152	71.97	5	129	15	127	2.7e-04	16.1	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
2852594813	147	33.56	2	69	5	53	9.6e-03	5.3	COG2867	Ribosome association toxin PasT (RatA) of the RatAB toxin-antitoxin module	146
2852594813	147	36.3	79	147	88	140	9.6e-03	5.3	COG2867	Ribosome association toxin PasT (RatA) of the RatAB toxin-antitoxin module	146
2852594814	359	93.52	2	358	7	381	2.7e-108	358.9	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2852594815	446	78.28	16	231	46	236	1.6e-35	118.3	COG2114	Adenylate cyclase, class 3	227
2852594817	1030	75.82	2	201	51	235	7.2e-40	133.6	COG2114	Adenylate cyclase, class 3	227
2852594818	1055	74.59	15	228	52	233	2.4e-38	128.7	COG2114	Adenylate cyclase, class 3	227
2852594821	852	4.51	24	134	2	24	2.5e-25	3.6	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
2852594821	852	24.9	714	852	383	509	2.5e-25	35.5	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
2852594821	852	26.08	242	395	368	500	2.5e-25	55.7	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
2852594822	229	96.46	4	228	2	219	3.2e-82	271.6	COG1136	ABC-type lipoprotein export system, ATPase component	226
2852594825	871	76.25	793	868	15	75	6.5e-18	59.6	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2852594826	147	82.19	2	145	6	125	1.8e-05	20.8	COG2867	Ribosome association toxin PasT (RatA) of the RatAB toxin-antitoxin module	146
2852594828	456	95.14	1	358	14	365	1.3e-75	251.3	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852594829	373	90.27	2	364	20	353	2.0e-69	230.9	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852594830	441	97.3	2	369	6	365	1.8e-82	273.7	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852594831	467	94.32	12	360	5	353	1.8e-78	260.2	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852594832	342	93.78	1	342	1	347	1.8e-79	264.1	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852594833	443	97.84	6	348	9	370	1.1e-64	215.3	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852594834	269	94.38	1	263	14	265	8.8e-70	231.5	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
2852594835	254	91.39	2	254	22	265	1.4e-74	247.1	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
2852594837	312	91.48	3	312	14	292	1.7e-35	119.2	COG0053	Divalent metal cation (Fe/Co/Zn/Cd) transporter	304
2852594839	326	96.57	1	326	3	312	3.1e-44	148.4	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2852594840	519	98.79	1	519	1	491	2.3e-103	343.4	COG1233	Phytoene dehydrogenase-related protein	487
2852594841	201	94.74	1	199	6	203	1.3e-18	65	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852594843	262	68.46	2	261	21	198	1.7e-27	93	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2852594844	140	80.25	1	137	10	135	2.2e-07	27.4	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
2852594845	155	64.12	13	142	48	131	8.2e-11	38.5	COG5485	Predicted ester cyclase	131
2852594846	207	82.3	7	205	13	184	1.1e-18	65.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852594847	248	74.23	2	247	23	215	6.4e-30	100.7	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2852594848	260	97.64	4	256	5	252	1.4e-66	221.1	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
2852594849	337	98.49	4	335	4	329	2.9e-110	365.4	COG1995	4-hydroxy-L-threonine phosphate dehydrogenase PdxA	332
2852594850	361	33.01	3	137	2	138	3.1e-37	71.8	COG3395	Uncharacterized conserved protein YgbK, DUF1537 family	413
2852594850	361	53.73	139	354	192	414	3.1e-37	50.8	COG3395	Uncharacterized conserved protein YgbK, DUF1537 family	413
2852594851	227	96.64	2	225	4	262	2.0e-43	144.9	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852594852	393	93.7	7	392	20	376	2.7e-70	234	COG4692	Predicted neuraminidase (sialidase)	381
2852594853	524	97.58	10	524	8	571	4.4e-68	227	COG0747	ABC-type transport system, periplasmic component	556
2852594854	337	99.06	27	333	3	317	3.4e-100	332	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2852594855	312	92.28	11	295	15	289	8.5e-88	290.5	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2852594856	269	81.54	4	268	2	266	4.9e-98	324.5	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
2852594857	265	45.83	1	251	295	547	6.2e-93	308.7	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
2852594858	315	93.75	1	311	14	313	1.4e-82	273.8	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2852594859	254	97.65	1	253	5	253	5.2e-58	192.8	COG3836	2-keto-3-deoxy-L-rhamnonate aldolase RhmA	255
2852594861	293	82.97	7	272	2	230	2.1e-43	145.1	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
2852594862	144	87.97	9	141	15	131	6.5e-24	80.9	COG1846	DNA-binding transcriptional regulator, MarR family	126
2852594863	334	100	1	334	1	331	5.0e-96	318.2	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2852594864	446	98.1	4	429	5	417	3.1e-89	296.2	COG2124	Cytochrome P450	411
2852594865	289	90.3	5	252	3	244	1.8e-49	165.2	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852594866	301	97.29	7	292	6	292	1.4e-39	133	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852594867	451	98.81	10	436	2	417	5.8e-87	288.7	COG2124	Cytochrome P450	411
2852594868	494	99.1	1	450	4	445	0.0e+00	472.8	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
2852594869	206	88.52	3	202	12	196	7.4e-18	62.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852594871	768	91.65	25	556	8	523	1.1e-124	413.2	COG0659	Sulfate permease or related transporter, MFS superfamily	554
2852594873	256	98.71	31	256	2	230	1.1e-83	276.7	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2852594878	121	88.72	1	120	7	124	2.2e-28	95.5	COG2346	Truncated hemoglobin YjbI	133
2852594879	382	64.26	9	374	2	303	6.6e-56	186.8	COG0515	Serine/threonine protein kinase	384
2852594881	282	74.09	26	261	6	228	1.8e-15	53.3	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
2852594883	304	90	1	281	31	300	1.2e-107	356.3	COG3662	Uncharacterized conserved protein, DUF2236 family	300
2852594884	194	89.95	4	194	13	200	6.4e-13	46.3	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852594889	361	94.46	1	318	17	323	3.4e-105	348.4	COG0042	tRNA-dihydrouridine synthase	323
2852594890	678	37.72	173	296	3	128	1.2e-72	55.3	COG1316	Anionic cell wall polymer biosynthesis enzyme,  LytR-Cps2A-Psr (LCP) family	307
2852594890	678	52.1	293	517	115	288	1.2e-72	184.5	COG1316	Anionic cell wall polymer biosynthesis enzyme,  LytR-Cps2A-Psr (LCP) family	307
2852594891	222	90.61	1	220	10	231	1.1e-58	195	COG0704	Phosphate uptake regulator	240
2852594892	307	100	2	307	1	331	1.9e-62	206.8	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2852594893	258	97.64	1	258	7	254	4.1e-121	399.6	COG1117	ABC-type phosphate transport system, ATPase component	253
2852594894	304	96.6	11	303	7	290	5.5e-86	284.7	COG0581	ABC-type phosphate transport system, permease component	292
2852594895	351	94.27	35	351	12	307	2.1e-87	289.4	COG0573	ABC-type phosphate transport system, permease component	310
2852594896	378	96.31	4	367	12	324	1.4e-74	247.6	COG0226	ABC-type phosphate transport system, periplasmic component	318
2852594897	295	48.68	7	120	41	132	4.7e-23	19.1	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2852594897	295	65.61	97	295	44	167	4.7e-23	59	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2852594898	260	86.21	12	222	31	230	3.8e-41	137.3	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2852594900	140	67.33	9	133	25	125	3.5e-09	33.7	COG0526	Thiol-disulfide isomerase or thioredoxin	127
2852594901	160	46.49	8	156	107	212	2.6e-02	10.7	COG0705	Membrane associated serine protease, rhomboid family	228
2852594902	277	96.86	1	277	8	285	6.2e-99	327.3	COG2897	3-mercaptopyruvate sulfurtransferase SseA, contains two rhodanese domains	285
2852594908	279	93.99	1	275	7	272	2.8e-33	111.6	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2852594909	365	97.28	11	363	8	329	3.6e-34	114.4	COG0530	Ca2+/Na+ antiporter	320
2852594911	291	78.28	78	288	41	231	5.1e-30	100.9	COG2114	Adenylate cyclase, class 3	227
2852594912	292	96.84	8	292	6	281	7.9e-50	166.7	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
2852594913	357	97.4	20	350	2	301	1.6e-76	254.3	COG0354	Folate-binding Fe-S cluster repair protein YgfZ, possible role in tRNA modification	305
2852594915	357	97.97	7	351	4	341	0.0e+00	445.1	COG0150	Phosphoribosylaminoimidazole (AIR) synthetase	345
2852594916	143	54.2	15	129	33	103	4.8e-08	29.3	COG1917	Cupin domain protein related to quercetin dioxygenase	131
2852594917	319	96.01	6	295	3	267	2.1e-55	184.5	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
2852594918	508	98.72	11	485	2	465	0.0e+00	634.3	COG0034	Glutamine phosphoribosylpyrophosphate amidotransferase	470
2852594920	401	98.38	3	350	7	370	3.2e-87	289.5	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852594921	140	62.65	7	133	18	121	2.1e-06	24.4	COG3467	Nitroimidazol reductase NimA or a related FMN-containing flavoprotein, pyridoxamine 5'-phosphate oxidase superfamily	166
2852594922	291	58.89	1	236	19	220	1.9e-44	148.6	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852594923	263	98.88	5	251	3	267	1.1e-61	205.2	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852594924	213	90.87	1	201	14	222	5.9e-12	42.1	COG1266	Membrane protease YdiL, CAAX protease family	226
2852594925	574	92.01	4	569	43	583	0.0e+00	549.7	COG4425	Uncharacterized membrane protein	588
2852594926	768	99.34	10	761	4	755	0.0e+00	876.5	COG0046	Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain	743
2852594927	610	98.02	9	574	3	546	0.0e+00	503.4	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
2852594928	115	86.61	1	115	14	123	9.5e-06	22.4	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
2852594929	418	97.51	1	418	9	438	0.0e+00	531.1	COG1362	Aspartyl aminopeptidase	437
2852594930	343	90.16	3	318	26	355	7.7e-82	271.7	COG2837	Periplasmic deferrochelatase/peroxidase EfeB	352
2852594931	265	99.25	1	265	1	265	1.6e-120	398.1	COG1659	Uncharacterized protein, linocin/CFP29 family	267
2852594936	440	79.38	1	90	6	82	1.8e-04	15.8	COG4842	Uncharacterized conserved protein YukE	97
2852594938	224	98.36	1	222	3	242	5.4e-79	261.4	COG0047	Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain	231
2852594939	79	95.18	1	79	3	81	1.3e-28	95.5	COG1828	Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component	83
2852594941	217	80.38	1	195	8	220	1.1e-17	60.4	COG2220	L-ascorbate metabolism protein UlaG, beta-lactamase superfamily	258
2852594942	547	99.09	1	546	4	550	0.0e+00	985.2	COG3573	Predicted oxidoreductase	552
2852594943	234	93.59	2	228	8	226	2.9e-73	242.3	COG3233	Predicted deacetylase	233
2852594944	163	97.53	1	163	3	160	1.0e-59	197	COG0386	Glutathione peroxidase, house-cleaning role in reducing lipid peroxides	162
2852594945	185	79.9	1	182	15	181	2.7e-13	47.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852594946	149	65.65	26	144	13	98	1.9e-20	69.7	COG4270	Uncharacterized membrane protein	131
2852594947	701	99.12	1	696	5	681	0.0e+00	931	COG1770	Protease II	682
2852594948	295	98.91	2	286	4	275	2.3e-86	285.9	COG0152	Phosphoribosylaminoimidazole-succinocarboxamide synthase	247
2852594950	163	71.32	36	159	26	117	2.8e-12	43	COG2852	Very-short-patch-repair endonuclease	129
2852594952	159	69.12	24	159	33	126	1.3e-05	21.6	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
2852594953	409	94.3	10	409	24	420	6.1e-97	321.6	COG2124	Cytochrome P450	411
2852594954	472	99.54	7	452	2	438	9.4e-130	429.7	COG0015	Adenylosuccinate lyase	438
2852594955	280	97.37	1	254	1	259	3.6e-73	242.4	COG4328	Predicted nuclease (RNAse H fold)	266
2852594956	206	96.08	1	205	4	199	1.6e-53	178	COG3226	DNA-binding transcriptional regulator YbjK	204
2852594957	278	91.79	1	257	4	249	1.8e-55	184.9	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852594958	192	78.95	1	192	6	170	3.7e-20	70	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852594959	298	47.12	20	292	6	144	2.3e-06	24.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852594960	422	98.83	1	420	2	425	0.0e+00	495.3	COG0151	Phosphoribosylamine-glycine ligase	428
2852594961	256	97.76	4	253	7	268	2.6e-45	150.9	COG1834	N-Dimethylarginine dimethylaminohydrolase	267
2852594962	409	92.64	6	409	31	420	1.3e-92	307.3	COG2124	Cytochrome P450	411
2852594963	199	88.04	7	197	12	195	1.6e-17	61.3	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852594964	361	96.57	5	360	3	340	1.7e-47	158.4	COG3804	Uncharacterized protein	350
2852594965	351	96.26	19	129	3	105	2.2e-13	46.1	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
2852594966	212	89.95	3	207	6	193	8.7e-13	45.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852594968	142	88.71	1	119	13	122	1.3e-17	60.5	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
2852594969	284	93.01	5	282	2	267	2.1e-69	230.3	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
2852594970	249	99.63	1	247	1	267	3.6e-68	226.5	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852594971	488	98.75	9	488	2	474	0.0e+00	511.7	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2852594972	194	75.6	8	184	6	163	5.2e-15	53.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852594973	398	92.87	2	397	29	419	5.4e-105	348.2	COG2124	Cytochrome P450	411
2852594974	275	92.16	7	255	4	250	2.2e-49	164.8	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852594975	450	98.34	2	449	7	420	1.6e-90	300.4	COG2124	Cytochrome P450	411
2852594976	68	98.53	3	65	2	68	3.1e-19	65.6	COG1141	Ferredoxin	68
2852594978	375	100	1	370	1	366	4.0e-126	417.6	COG1062	Zn-dependent alcohol dehydrogenase	366
2852594979	666	12.7	383	461	5	43	5.5e-11	22	COG0492	Thioredoxin reductase	305
2852594979	666	34.85	514	666	144	250	5.5e-11	14	COG0492	Thioredoxin reductase	305
2852594979	666	98.35	3	367	3	359	4.7e-96	318.4	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
2852594980	148	81.62	17	141	18	128	5.0e-04	16.4	COG3631	Ketosteroid isomerase-related protein	133
2852594981	276	96.27	1	245	10	267	5.6e-45	150.5	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852594982	515	76.04	23	475	23	406	3.6e-39	131.1	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
2852594984	271	35.1	10	256	3	128	2.4e-20	70.6	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2852594985	155	92.09	7	138	10	137	9.6e-17	56.9	COG2246	Putative flippase GtrA (transmembrane translocase of bactoprenol-linked glucose)	139
2852594986	1622	33.33	1006	1084	120	182	8.0e-12	4.7	COG3506	Regulation of enolase protein 1 (function unknown), concanavalin A-like superfamily	189
2852594986	1622	35.45	1138	1260	116	182	8.0e-12	11.4	COG3506	Regulation of enolase protein 1 (function unknown), concanavalin A-like superfamily	189
2852594986	1622	36.51	1319	1438	114	182	8.0e-12	6	COG3506	Regulation of enolase protein 1 (function unknown), concanavalin A-like superfamily	189
2852594986	1622	36.51	1484	1622	114	182	8.0e-12	13.6	COG3506	Regulation of enolase protein 1 (function unknown), concanavalin A-like superfamily	189
2852594986	1622	92.25	235	614	16	396	3.0e-47	157.1	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
2852594987	403	42.9	19	294	5	158	2.3e-12	44.2	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2852594988	134	99.29	1	132	1	140	1.4e-33	112.1	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
2852594989	478	85.03	76	476	56	390	3.9e-78	259.9	COG0642	Signal transduction histidine kinase	336
2852594990	237	99.14	11	237	2	231	3.1e-80	265.4	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2852594995	942	81.25	866	942	10	74	4.0e-16	53.1	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2852594997	101	12.42	3	88	371	425	8.1e-03	11.4	COG4452	Inner membrane protein involved in colicin E2 resistance	443
2852595001	412	65.71	14	313	17	269	1.2e-23	77.6	COG2850	Ribosomal protein L16 Arg81 hydroxylase, contains JmjC domain	383
2852595003	837	95.51	3	778	14	694	0.0e+00	483	COG0744	Membrane carboxypeptidase (penicillin-binding protein)	661
2852595006	908	6.21	18	506	326	368	5.4e-03	11.5	COG1241	DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family	682
2852595006	908	85	831	907	8	75	5.0e-20	66.4	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2852595008	420	19.41	216	318	9	81	8.9e-24	25.1	COG4399	Uncharacterized membrane protein YheB, UPF0754 family	376
2852595008	420	21.81	319	416	292	373	8.9e-24	23.8	COG4399	Uncharacterized membrane protein YheB, UPF0754 family	376
2852595008	420	27.39	20	171	5	107	8.9e-24	32.3	COG4399	Uncharacterized membrane protein YheB, UPF0754 family	376
2852595009	208	82.3	3	201	11	182	3.4e-15	53.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852595010	406	92.87	4	406	29	419	2.9e-87	289.7	COG2124	Cytochrome P450	411
2852595011	611	96.74	12	467	8	393	2.0e-76	253.8	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852595012	730	78.17	257	606	79	386	4.2e-72	240.5	COG0642	Signal transduction histidine kinase	336
2852595013	126	84.21	1	124	6	117	5.8e-36	119.9	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2852595014	369	94.26	134	368	2	231	5.1e-42	140.1	COG2114	Adenylate cyclase, class 3	227
2852595021	218	89.57	13	218	20	208	1.8e-64	213.7	COG2173	D-alanyl-D-alanine dipeptidase	211
2852595022	409	86.7	13	408	56	420	1.0e-89	297.8	COG2124	Cytochrome P450	411
2852595023	372	98.34	2	372	2	297	8.7e-93	307.2	COG1975	Xanthine and CO dehydrogenase maturation factor, XdhC/CoxF family	278
2852595024	771	99.33	6	769	4	743	0.0e+00	596.6	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
2852595025	230	98.63	1	148	1	144	4.3e-36	120.1	COG3427	Carbon monoxide dehydrogenase subunit G	146
2852595026	291	99.3	1	289	2	285	1.3e-66	221.7	COG1319	CO or xanthine dehydrogenase, FAD-binding subunit	284
2852595027	157	96.79	3	157	3	153	1.2e-66	219.7	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
2852595029	304	98.6	1	286	1	282	1.1e-79	264.1	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
2852595030	278	98.88	3	254	2	266	1.3e-61	205	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852595031	311	88.68	15	283	5	239	6.8e-55	182.5	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2852595036	488	95.72	5	488	15	484	0.0e+00	585.1	COG0380	Trehalose-6-phosphate synthase	486
2852595039	582	99.73	1	366	1	369	2.3e-74	247.1	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852595040	394	91.62	5	379	4	342	6.7e-65	216	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852595041	478	95.68	2	360	12	365	9.5e-78	258.1	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852595042	348	88.38	2	335	9	335	6.8e-75	248.9	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852595043	344	92.43	1	341	9	350	2.9e-78	260	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852595044	396	97.03	2	341	11	369	1.6e-67	224.5	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852595045	284	97.38	8	278	6	265	3.5e-74	245.8	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
2852595046	254	93.26	1	252	16	264	9.8e-84	277.1	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
2852595047	306	98.13	8	255	2	264	1.3e-51	172.2	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852595048	63	98.53	1	63	1	67	9.2e-20	67.4	COG1141	Ferredoxin	68
2852595049	396	98.5	3	394	4	396	3.2e-93	309.4	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852595050	363	99.25	1	363	1	396	2.6e-58	194.6	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852595051	499	90.85	16	492	43	558	1.2e-73	244	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2852595052	250	64.39	96	234	42	126	1.1e-09	34.5	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2852595053	131	77.4	10	129	9	121	7.7e-09	33.3	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2852595055	233	89.15	3	233	27	289	2.9e-16	56.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852595056	373	98.26	1	369	3	341	2.2e-70	233.5	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
2852595057	550	96.65	2	542	12	560	9.9e-95	314.3	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2852595058	269	97.74	8	266	7	265	3.7e-69	229.4	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2852595059	583	96.3	20	580	12	558	7.6e-84	278.4	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2852595060	409	93.59	3	403	27	420	4.2e-100	332.1	COG2124	Cytochrome P450	411
2852595062	343	92.71	2	340	3	320	2.8e-60	200	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852595063	329	92.2	25	157	8	137	2.3e-59	73.3	COG1545	Uncharacterized OB-fold protein, contains Zn-ribbon domain	140
2852595063	329	94.33	177	316	8	140	2.3e-59	120.3	COG1545	Uncharacterized OB-fold protein, contains Zn-ribbon domain	140
2852595064	351	99.49	1	351	1	392	1.6e-29	92.8	COG0183	Acetyl-CoA acetyltransferase	392
2852595065	389	97.97	3	386	4	389	2.9e-55	184.4	COG0183	Acetyl-CoA acetyltransferase	392
2852595066	292	71.43	3	290	18	262	1.2e-49	165.5	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852595067	133	77.94	8	131	21	126	1.2e-07	28.4	COG3631	Ketosteroid isomerase-related protein	133
2852595068	315	95.85	8	311	10	309	1.7e-40	135.5	COG2017	Galactose mutarotase or related enzyme	308
2852595069	330	99.72	4	330	2	353	3.8e-74	246	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
2852595070	340	99.1	10	340	2	332	1.2e-86	287.5	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2852595071	414	96.95	17	412	12	393	0.0e+00	465	COG4214	ABC-type xylose transport system, permease component	394
2852595072	509	98.8	1	507	6	500	0.0e+00	618.4	COG1129	ABC-type sugar transport system, ATPase component	500
2852595073	361	97.36	9	361	7	338	4.1e-127	420.5	COG4213	ABC-type xylose transport system, periplasmic component	341
2852595074	323	93.27	1	322	11	315	2.2e-66	220.5	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
2852595075	511	96.41	6	506	4	486	0.0e+00	588.1	COG1129	ABC-type sugar transport system, ATPase component	500
2852595076	357	95.3	1	332	11	314	1.4e-75	250.7	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
2852595077	333	95.3	17	333	9	312	3.1e-81	269.2	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
2852595078	338	98.8	10	336	3	332	5.0e-91	302	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2852595079	555	97.98	3	550	2	535	0.0e+00	528.2	COG1069	Ribulose kinase	544
2852595080	234	92.86	8	224	6	213	1.8e-55	184.3	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
2852595081	503	98.19	4	500	7	494	0.0e+00	649	COG2160	L-arabinose isomerase	497
2852595082	328	44.44	1	141	3	122	6.4e-31	42.2	COG3217	Uncharacterized conserved protein YcbX, contains MOSC and Fe-S domains	270
2852595082	328	47.41	136	302	134	261	6.4e-31	60	COG3217	Uncharacterized conserved protein YcbX, contains MOSC and Fe-S domains	270
2852595083	175	96.61	1	175	4	174	3.9e-53	176	COG0663	Carbonic anhydrase or acetyltransferase, isoleucine patch superfamily	176
2852595084	382	92.29	15	378	26	372	5.2e-52	173.7	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
2852595088	260	98.51	3	258	3	266	1.1e-56	188.9	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852595090	301	22.36	235	296	191	245	3.2e-30	8.5	COG1414	DNA-binding transcriptional regulator, IclR family	246
2852595090	301	74.39	12	196	3	185	3.2e-30	91.4	COG1414	DNA-binding transcriptional regulator, IclR family	246
2852595091	702	11.63	428	522	354	423	1.7e-125	6.8	COG0514	Superfamily II DNA helicase RecQ	590
2852595091	702	70.93	10	456	2	428	1.7e-125	411.5	COG0514	Superfamily II DNA helicase RecQ	590
2852595093	328	96.23	13	327	10	315	1.5e-47	156.8	COG0701	Uncharacterized membrane protein YraQ, UPF0718 family	317
2852595096	350	81.84	11	350	2	339	1.6e-60	201.8	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
2852595097	305	99.68	1	303	1	309	0.0e+00	520.4	COG4569	Acetaldehyde dehydrogenase (acetylating)	310
2852595098	261	98.86	1	261	1	261	4.8e-100	330.7	COG3971	2-keto-4-pentenoate hydratase	264
2852595099	560	94.7	1	559	3	538	2.0e-57	191.1	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
2852595100	286	66.04	144	277	16	120	1.4e-25	85.2	COG2030	Acyl dehydratase	159
2852595106	388	96.7	6	387	3	383	1.3e-57	192.2	COG0183	Acetyl-CoA acetyltransferase	392
2852595108	322	86.16	2	170	17	153	2.6e-06	21.8	COG2030	Acyl dehydratase	159
2852595108	322	87.94	184	320	6	129	2.1e-22	74.9	COG1545	Uncharacterized OB-fold protein, contains Zn-ribbon domain	140
2852595109	387	97.99	1	385	4	394	2.3e-79	263.8	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852595110	332	83.21	4	332	44	375	2.4e-40	135.3	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852595111	415	92.64	2	409	29	418	1.3e-93	310.7	COG2124	Cytochrome P450	411
2852595112	387	99.49	1	387	2	393	4.3e-114	378.2	COG0183	Acetyl-CoA acetyltransferase	392
2852595115	242	16.26	113	186	139	171	2.3e-05	2.7	COG3917	2-hydroxychromene-2-carboxylate isomerase	203
2852595115	242	18.23	2	82	10	46	2.3e-05	16.2	COG3917	2-hydroxychromene-2-carboxylate isomerase	203
2852595116	301	98.88	2	261	3	267	2.6e-55	184.3	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852595117	256	98.51	9	244	3	266	9.1e-58	192.4	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852595118	252	89.06	1	250	6	241	5.9e-54	179.7	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2852595119	291	99.09	1	236	2	219	1.1e-60	201.1	COG1788	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit	220
2852595120	247	99.11	1	226	2	224	2.6e-47	157.5	COG2057	Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit	225
2852595121	353	98.84	2	352	3	343	1.4e-90	300.6	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
2852595122	371	99.73	1	369	1	365	6.7e-119	393.9	COG1062	Zn-dependent alcohol dehydrogenase	366
2852595123	382	99.75	1	382	1	393	5.9e-121	400.7	COG0183	Acetyl-CoA acetyltransferase	392
2852595124	200	73.21	2	196	13	165	9.9e-24	81.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852595125	262	97.39	14	261	3	263	8.4e-62	205.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852595126	382	97.49	3	380	9	397	3.8e-82	272.9	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852595127	506	96.3	2	506	11	557	3.6e-113	375.3	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2852595128	374	99.25	1	374	2	397	5.2e-72	239.6	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852595129	317	33.08	1	142	1	132	2.2e-40	40.4	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852595129	317	36.59	167	317	246	391	2.2e-40	100.6	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852595130	313	30.83	1	120	7	129	4.4e-38	37.9	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852595130	313	32.33	177	312	251	379	4.4e-38	95.8	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852595131	272	58.42	1	265	17	179	1.5e-09	35	COG0500	SAM-dependent methyltransferase	257
2852595132	383	96.21	3	383	11	391	3.8e-106	351.9	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
2852595133	640	98.91	81	616	1	546	0.0e+00	472.9	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2852595134	248	99.25	2	247	2	267	1.6e-62	207.9	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852595135	458	46.48	249	448	16	193	2.9e-40	38.2	COG0477	MFS family permease	338
2852595135	458	60.84	21	284	4	236	2.9e-40	103.1	COG0477	MFS family permease	338
2852595136	304	97.67	9	298	4	297	4.5e-43	144.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2852595137	82	50	1	72	15	56	1.6e-04	18.2	COG5450	Transcription regulator of the Arc/MetJ class	84
2852595138	144	99.29	1	140	1	140	1.7e-26	90	COG1848	Predicted nucleic acid-binding protein, contains PIN domain	140
2852595139	259	39.94	2	141	17	139	1.8e-33	83.1	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
2852595139	259	42.21	127	256	174	303	1.8e-33	31.8	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
2852595141	391	99.24	1	386	2	395	5.9e-114	377.3	COG0754	Glutathionylspermidine synthase	387
2852595143	89	17.66	3	88	30	88	3.1e+00	3.3	COG4371	Uncharacterized membrane protein	334
2852595146	188	87.57	2	174	10	171	4.6e-45	150	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
2852595147	300	75.34	141	281	2	111	1.6e-09	33.2	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2852595148	296	97.29	22	295	7	293	5.6e-45	150.6	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852595149	394	95.24	6	385	10	389	6.1e-44	146.5	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852595150	352	97.76	6	289	4	265	9.3e-76	251.2	COG1018	Ferredoxin-NADP reductase	266
2852595152	703	31.83	2	134	6	132	6.1e-96	29.9	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852595152	703	33.33	141	337	246	378	6.1e-96	79.5	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852595152	703	96.49	320	703	12	396	6.1e-96	220.7	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852595153	201	89	6	197	10	195	5.0e-23	79.3	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852595154	845	12.18	259	378	23	98	3.1e-80	14	COG3387	Glucoamylase (glucan-1,4-alpha-glucosidase), GH15 family	612
2852595154	845	61.38	444	845	235	617	3.1e-80	251.5	COG3387	Glucoamylase (glucan-1,4-alpha-glucosidase), GH15 family	612
2852595154	845	89.55	7	257	18	257	2.2e-40	134.8	COG1877	Trehalose-6-phosphatase	266
2852595155	366	99.4	11	366	1	332	7.2e-77	255.3	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2852595156	304	98.36	5	298	5	304	1.8e-60	201	COG0803	ABC-type Zn uptake system ZnuABC, Zn-binding component ZnuA	303
2852595157	271	95.28	4	260	6	247	4.0e-63	209.5	COG1121	ABC-type Mn2+/Zn2+ transport system, ATPase component	254
2852595158	288	97.46	14	286	4	272	8.3e-61	202.2	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
2852595159	538	96.13	21	537	16	561	3.0e-115	382.1	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2852595160	268	96.52	2	268	9	285	4.2e-65	215.6	COG2897	3-mercaptopyruvate sulfurtransferase SseA, contains two rhodanese domains	285
2852595161	219	93.52	10	208	4	205	4.2e-35	118	COG0778	Nitroreductase	207
2852595162	252	98.41	1	252	3	250	4.6e-105	347	COG1540	Lactam utilization protein B (function unknown)	252
2852595163	84	86.08	1	78	12	79	6.3e-26	87.4	COG0238	Ribosomal protein S18	75
2852595164	306	95.47	21	296	3	255	3.7e-29	98.1	COG2220	L-ascorbate metabolism protein UlaG, beta-lactamase superfamily	258
2852595165	411	99.06	2	405	4	423	4.4e-83	275.7	COG1055	Na+/H+ antiporter NhaD or related arsenite permease	424
2852595166	252	91.86	2	194	11	213	5.3e-18	62	COG2755	Lysophospholipase L1 or related esterase	216
2852595167	314	96.2	47	314	9	261	7.5e-80	264.4	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
2852595168	470	99.35	3	465	2	463	0.0e+00	522.6	COG0215	Cysteinyl-tRNA synthetase	464
2852595169	159	98.11	5	159	2	157	5.7e-54	179	COG0245	2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	159
2852595170	162	96.99	1	162	3	163	7.6e-69	227.3	COG1329	RNA polymerase-interacting regulator, CarD/CdnL/TRCF family	166
2852595171	184	21.43	133	180	114	146	2.0e-06	11.4	COG2847	Copper(I)-binding protein	151
2852595171	184	32.47	24	96	21	70	2.0e-06	11	COG2847	Copper(I)-binding protein	151
2852595172	461	99.34	1	453	2	454	0.0e+00	569.8	COG1066	Predicted ATP-dependent serine protease	456
2852595173	372	97.42	11	363	9	348	0.0e+00	524	COG1623	Diadenylate cyclase (c-di-AMP synthetase), DNA integrity scanning protein DisA	349
2852595177	206	92.31	7	204	3	194	8.8e-50	165.8	COG0288	Carbonic anhydrase	207
2852595178	299	78.81	5	295	13	291	3.6e-86	286.2	COG1194	Adenine-specific DNA glycosylase, acts on AG and A-oxoG pairs	342
2852595179	454	75.41	264	454	50	233	2.3e-36	122.1	COG2114	Adenylate cyclase, class 3	227
2852595180	328	96	2	318	9	320	1.9e-85	283	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
2852595182	256	92.88	3	252	20	293	5.2e-32	108.1	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852595183	107	96.23	5	107	3	104	2.4e-31	104.5	COG2329	Heme-degrading monooxygenase HmoA and related ABM domain proteins	105
2852595184	458	97.6	97	457	4	329	1.7e-63	211.2	COG2367	Beta-lactamase class A	329
2852595185	393	80.91	2	387	29	418	1.6e-26	89.3	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
2852595186	618	89.52	16	566	3	540	0.0e+00	536.5	COG1086	NDP-sugar epimerase, includes UDP-GlcNAc-inverting 4,6-dehydratase FlaA1 and capsular polysaccharide biosynthesis protein EpsC	588
2852595187	504	79.37	223	465	39	265	7.6e-45	149.9	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
2852595189	351	64.3	11	349	139	401	8.3e-15	51.9	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2852595191	381	67.73	24	378	116	392	5.7e-36	120.2	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2852595192	316	97.82	1	315	3	316	7.8e-67	222.5	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2852595193	190	81.78	1	189	40	223	6.8e-63	208.4	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
2852595194	183	90.91	4	183	4	193	2.0e-22	76.3	COG0406	Broad specificity phosphatase PhoE	208
2852595195	241	95.42	1	234	5	233	2.4e-06	21.6	COG5446	Uncharacterized membrane protein, predicted cobalt tansporter CbtA	233
2852595198	123	95.37	1	105	2	104	1.8e-33	111.3	COG0393	Uncharacterized conserved protein YbjQ, UPF0145 family	108
2852595199	849	98.88	4	824	1	796	0.0e+00	1113.6	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
2852595202	409	80.35	1	408	100	508	0.0e+00	541.1	COG1190	Lysyl-tRNA synthetase (class II)	502
2852595204	405	95.15	39	405	19	371	1.6e-73	243.9	COG3616	D-serine deaminase, pyridoxal phosphate-dependent	368
2852595205	271	99.6	1	259	2	253	3.5e-86	285.4	COG1521	Pantothenate kinase type III	251
2852595206	131	92.06	1	122	4	119	1.3e-54	179.9	COG0853	Aspartate 1-decarboxylase	126
2852595207	311	98.6	11	288	3	283	2.3e-106	351.5	COG0414	Panthothenate synthetase	285
2852595208	314	99.31	2	303	2	288	4.1e-122	403.5	COG5495	Predicted oxidoreductase, contains short-chain dehydrogenase (SDR) and DUF2520 domains	289
2852595211	170	98.14	1	164	1	158	3.4e-47	156.5	COG0801	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase	160
2852595212	127	99.17	1	120	1	120	1.7e-37	124.9	COG1539	Dihydroneopterin aldolase	121
2852595213	272	94.24	1	272	8	269	2.3e-91	302.5	COG0294	Dihydropteroate synthase	274
2852595214	211	95.43	12	211	8	195	9.8e-82	269.4	COG0302	GTP cyclohydrolase I	195
2852595215	777	98.84	7	610	6	599	0.0e+00	828.5	COG0465	ATP-dependent Zn proteases	596
2852595216	298	98.31	6	295	4	293	4.3e-44	147.7	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852595217	397	97.67	11	350	6	340	5.7e-62	206.1	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852595218	338	100	1	338	1	353	1.1e-63	210.7	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
2852595219	246	97.54	6	246	6	243	6.8e-63	209.1	COG2968	Uncharacterized conserved protein YggE, contains kinase-interacting SIMPL domain	243
2852595220	739	93.83	3	739	48	807	5.1e-101	335.6	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2852595222	192	97.21	6	188	5	178	2.3e-71	235.4	COG0634	Hypoxanthine-guanine phosphoribosyltransferase	178
2852595223	320	76.3	14	279	23	257	2.6e-39	131.4	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
2852595224	350	93.87	4	350	22	358	1.1e-116	386.6	COG5282	Uncharacterized conserved protein, DUF2342 family	359
2852595225	460	81.09	1	460	90	475	1.1e-79	264.2	COG2027	D-alanyl-D-alanine carboxypeptidase	470
2852595226	162	91.28	1	159	16	172	2.4e-63	209.5	COG0221	Inorganic pyrophosphatase	171
2852595227	173	75	11	168	40	171	5.5e-16	55.5	COG3195	2-oxo-4-hydroxy-4-carboxy--5-ureidoimidazoline (OHCU) decarboxylase	176
2852595231	1347	32.33	1129	1297	158	318	1.5e-109	85.6	COG2319	WD40 repeat	466
2852595231	1347	44.18	726	959	247	466	1.5e-109	121.3	COG2319	WD40 repeat	466
2852595231	1347	53.01	875	1135	203	466	1.5e-109	174.9	COG2319	WD40 repeat	466
2852595232	383	89.85	3	383	33	395	3.8e-57	190.8	COG1680	CubicO group peptidase, beta-lactamase class C family	390
2852595233	431	94.34	6	422	9	375	2.6e-47	156.5	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
2852595235	339	96.48	53	334	2	248	1.6e-62	207.7	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
2852595236	209	92.79	11	209	13	205	2.8e-54	180.2	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
2852595237	1308	16.3	29	139	37	126	8.6e-51	33.3	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2852595237	1308	44.74	1202	1286	88	172	8.8e-19	23.2	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
2852595237	1308	46.32	690	820	86	173	8.8e-19	43	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
2852595237	1308	64.13	144	501	184	537	8.6e-51	133.9	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2852595238	449	53.17	3	448	9	469	3.5e-69	230.1	COG0308	Aminopeptidase N	859
2852595239	413	76.35	12	408	15	382	3.4e-07	24.9	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
2852595240	238	49.03	12	234	5	180	1.3e-19	68	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2852595241	113	90.08	1	113	8	116	8.3e-08	29	COG2456	Uncharacterized protein	121
2852595242	195	92.82	1	194	7	200	7.3e-13	46.2	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852595243	593	97.58	1	593	6	570	0.0e+00	791	COG3653	N-acyl-D-aspartate/D-glutamate deacylase	579
2852595244	311	98.44	1	311	2	317	1.2e-96	320.6	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2852595246	122	86.29	6	122	14	120	1.8e-26	89.3	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
2852595247	292	99.66	7	289	1	294	4.2e-41	138	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852595249	402	13.68	300	400	279	358	4.2e-33	14.4	COG2812	DNA polymerase III, gamma/tau subunits	515
2852595249	402	29.74	3	194	15	188	4.2e-33	95	COG2812	DNA polymerase III, gamma/tau subunits	515
2852595250	535	93.03	254	525	5	231	2.2e-54	180.5	COG2114	Adenylate cyclase, class 3	227
2852595251	931	97.22	15	626	2	560	0.0e+00	680.3	COG0550	DNA topoisomerase IA	570
2852595253	67	98.51	1	67	1	66	3.9e-35	116.3	COG1278	Cold shock protein, CspA family	67
2852595254	776	90.53	6	775	24	807	0.0e+00	785	COG1205	ATP-dependent helicase YprA,  contains C-terminal metal-binding DUF1998 domain	851
2852595256	106	15.4	1	103	18	104	2.6e-04	16.4	COG4655	Uncharacterized membrane protein	565
2852595259	189	43.93	6	185	177	317	6.4e-15	51.6	COG2064	Pilus assembly protein TadC	320
2852595260	260	69.9	27	259	91	306	3.2e-49	163.9	COG4965	Flp pilus assembly protein TadB	309
2852595261	388	89.5	20	372	30	353	8.8e-119	392.9	COG4962	Pilus assembly protein, ATPase of CpaF family	355
2852595264	285	95.75	22	250	5	207	9.7e-57	188.2	COG0560	Phosphoserine phosphatase	212
2852595267	648	100	66	634	1	552	0.0e+00	802.5	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2852595269	169	94.66	18	147	6	129	9.2e-06	22	COG5393	Uncharacterized membrane protein YqjE	131
2852595270	314	99.32	16	312	2	294	2.0e-41	139	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852595271	396	70.41	1	392	2	258	5.4e-17	57.7	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2852595272	260	77.33	46	202	14	146	8.3e-15	51.3	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2852595273	218	78.67	51	192	29	146	7.4e-10	35.8	COG0526	Thiol-disulfide isomerase or thioredoxin	127
2852595274	265	96.21	33	240	5	207	3.2e-76	251.5	COG0177	Endonuclease III	211
2852595276	224	95.41	4	216	5	212	4.1e-54	179.8	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2852595277	258	88.85	12	249	19	249	3.6e-34	114.8	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2852595278	151	93.38	6	151	8	134	3.6e-22	75.2	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
2852595280	339	96.99	19	339	2	323	1.7e-52	175.3	COG0003	Anion-transporting ATPase, ArsA/GET3 family	322
2852595281	380	99.1	18	357	1	329	4.6e-72	239.7	COG0003	Anion-transporting ATPase, ArsA/GET3 family	322
2852595283	820	96.91	6	781	10	700	0.0e+00	523.8	COG0744	Membrane carboxypeptidase (penicillin-binding protein)	661
2852595284	318	97.95	12	298	5	291	9.7e-67	221.7	COG1408	Predicted phosphohydrolase, MPP superfamily	284
2852595285	369	98.01	24	338	6	301	3.8e-71	236	COG0031	Cysteine synthase	300
2852595289	202	90.27	11	202	4	207	5.4e-47	156.9	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
2852595290	304	79	1	265	54	290	1.7e-30	102.8	COG3662	Uncharacterized conserved protein, DUF2236 family	300
2852595291	203	91.39	3	196	14	204	1.2e-21	74.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852595292	150	35.04	11	150	52	147	1.8e-03	14.9	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
2852595293	301	86.09	3	301	35	325	1.0e-43	146	COG1477	Thiamine biosynthesis lipoprotein ApbE	337
2852595294	186	35.68	2	175	44	200	6.2e-10	35.1	COG4097	Predicted ferric reductase	438
2852595295	391	88.68	32	383	47	422	2.5e-59	194.9	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
2852595296	87	95.59	9	75	2	66	1.5e-09	34.6	COG1141	Ferredoxin	68
2852595297	226	97.84	8	226	3	229	8.7e-64	211.5	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2852595298	418	76.65	10	416	87	388	4.4e-51	170.6	COG0642	Signal transduction histidine kinase	336
2852595301	71	62.5	13	68	3	52	2.7e-05	20.6	COG3369	Uncharacterized protein, contains Zn-finger domain of CDGSH type	78
2852595302	231	57.14	6	207	87	250	4.8e-33	110.9	COG2890	Methylase of polypeptide chain release factors	280
2852595305	328	90.96	1	324	4	315	2.7e-43	144.8	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852595306	154	98.65	2	154	2	147	8.1e-52	172	COG1610	Uncharacterized conserved protein YqeY	148
2852595310	325	96.97	7	325	10	329	1.5e-108	359.3	COG0714	MoxR-like ATPase	329
2852595311	438	98.32	1	434	7	416	1.3e-88	294.5	COG1721	Uncharacterized conserved protein, DUF58 family, contains vWF domain	416
2852595312	330	96.62	89	296	2	201	6.2e-46	152.8	COG1300	Uncharacterized membrane protein SpoIIM, required for sporulation	207
2852595313	290	92.61	4	172	2	164	1.6e-33	111.1	COG1714	Uncharacterized membrane protein YckC, RDD family	172
2852595314	164	96.23	3	163	6	158	2.6e-32	108.9	COG5500	Uncharacterized membrane protein	159
2852595316	211	84.69	1	208	7	183	2.7e-25	86.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852595317	319	85.61	187	314	13	125	6.5e-25	83.5	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2852595318	385	94.25	1	384	9	385	1.4e-36	122.6	COG0475	Kef-type K+ transport system, membrane component KefB	397
2852595319	124	31.43	30	103	55	87	1.7e-02	10.8	COG0278	Glutaredoxin-related protein	105
2852595320	443	94.69	4	443	24	487	4.1e-115	381.3	COG3670	Carotenoid cleavage dioxygenase or a related enzyme	490
2852595321	192	59.85	2	149	9	90	1.5e-22	76	COG1695	DNA-binding transcriptional regulator, PadR family	138
2852595323	246	65.69	97	236	5	94	2.6e-26	87.9	COG1695	DNA-binding transcriptional regulator, PadR family	138
2852595324	290	97.19	1	290	1	311	8.0e-57	183.9	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2852595326	505	98.6	1	504	6	499	0.0e+00	741.5	COG0554	Glycerol kinase	499
2852595327	255	51.97	18	249	42	186	3.4e-06	24.1	COG0500	SAM-dependent methyltransferase	257
2852595331	225	55.91	3	224	54	209	1.8e-15	54.3	COG0500	SAM-dependent methyltransferase	257
2852595332	456	97.37	15	440	4	410	0.0e+00	447.3	COG1301	Na+/H+-dicarboxylate symporter	415
2852595333	374	96.33	2	373	11	404	3.2e-48	160.4	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
2852595334	321	100	1	321	1	323	0.0e+00	458.7	COG4301	Uncharacterized conserved protein, contains predicted SAM-dependent methyltransferase domain	321
2852595335	230	96.48	1	223	1	247	1.2e-40	131.7	COG0121	Predicted glutamine amidotransferase	252
2852595336	424	98.2	79	424	5	331	5.4e-77	255.7	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
2852595337	430	90.79	5	430	27	440	5.3e-117	387.7	COG3572	Gamma-glutamylcysteine synthetase	456
2852595339	142	96.5	1	141	5	142	3.2e-44	147.1	COG1764	Organic hydroperoxide reductase OsmC/OhrA	143
2852595343	343	99.7	1	341	1	335	5.3e-114	377.7	COG0136	Aspartate-semialdehyde dehydrogenase	334
2852595344	421	99.32	1	408	3	442	0.0e+00	463.9	COG0527	Aspartokinase	447
2852595345	205	86.57	19	194	7	193	7.3e-16	52.3	COG0778	Nitroreductase	207
2852595347	417	98.79	1	417	1	407	0.0e+00	442.9	COG0004	Ammonia channel protein AmtB	409
2852595348	433	98.43	2	432	7	445	4.1e-110	364.9	COG0174	Glutamine synthetase	443
2852595349	290	11.83	1	48	12	55	2.2e-37	21	COG0067	Glutamate synthase domain 1	371
2852595349	290	54.84	79	290	164	367	2.2e-37	102.3	COG0067	Glutamate synthase domain 1	371
2852595350	228	62.17	15	222	64	252	1.7e-29	99.7	COG0070	Glutamate synthase domain 3	301
2852595351	435	74.03	1	417	120	481	4.3e-113	371.8	COG0069	Glutamate synthase domain 2	485
2852595352	393	98.71	1	380	3	385	1.5e-75	251.4	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2852595353	215	38.17	106	208	51	100	8.1e-06	21.9	COG1917	Cupin domain protein related to quercetin dioxygenase	131
2852595353	215	84.06	28	101	5	62	1.2e-08	30.5	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
2852595355	606	99.27	72	520	2	411	0.0e+00	453	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
2852595356	188	61.27	1	142	10	134	1.6e-15	53.7	COG3226	DNA-binding transcriptional regulator YbjK	204
2852595358	149	97.26	6	138	3	144	1.2e-10	39	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2852595359	361	34.62	229	360	245	379	4.1e-22	35	COG0006	Xaa-Pro aminopeptidase	384
2852595359	361	53.33	21	236	11	218	4.1e-22	38.6	COG0006	Xaa-Pro aminopeptidase	384
2852595360	385	95.13	1	381	10	380	4.5e-48	158.8	COG0006	Xaa-Pro aminopeptidase	384
2852595361	420	94.06	2	410	25	420	1.1e-75	251.6	COG2124	Cytochrome P450	411
2852595362	329	87.8	7	246	19	241	2.4e-43	145.3	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
2852595363	409	91.32	1	409	32	473	1.0e-68	228.9	COG0769	UDP-N-acetylmuramyl tripeptide synthase	475
2852595364	238	96.8	3	237	3	244	3.6e-92	304.5	COG3442	Glutamine amidotransferase related to the GATase domain of CobQ	250
2852595366	199	97.98	1	198	4	197	2.3e-82	271.7	COG0353	Recombinational DNA repair protein RecR	198
2852595367	110	92.38	4	110	6	102	1.2e-34	115	COG0718	Conserved DNA-binding protein YbaB (function unknown)	105
2852595368	251	77.07	12	246	62	266	3.5e-48	160.7	COG0860	N-acetylmuramoyl-L-alanine amidase	231
2852595369	146	16.44	4	34	4	27	1.8e-03	5	COG3427	Carbon monoxide dehydrogenase subunit G	146
2852595369	146	40.41	55	146	86	144	1.8e-03	7.6	COG3427	Carbon monoxide dehydrogenase subunit G	146
2852595370	459	88.06	8	456	52	464	9.0e-46	153	COG0277	FAD/FMN-containing dehydrogenase	459
2852595371	436	96.5	137	418	10	285	2.3e-99	328.5	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
2852595372	138	72.87	13	138	26	119	6.3e-17	58.1	COG2852	Very-short-patch-repair endonuclease	129
2852595374	623	95.38	1	614	5	562	0.0e+00	469.3	COG2812	DNA polymerase III, gamma/tau subunits	515
2852595375	427	87.72	7	422	52	451	1.1e-71	238.4	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
2852595380	339	88.49	8	339	35	357	3.1e-55	184.2	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2852595381	356	97.43	6	355	4	344	2.6e-67	223.7	COG3804	Uncharacterized protein	350
2852595382	428	91.09	2	403	32	399	2.2e-51	171.7	COG1680	CubicO group peptidase, beta-lactamase class C family	390
2852595384	648	65.53	7	340	2	309	1.5e-57	191.9	COG0515	Serine/threonine protein kinase	384
2852595387	354	98.54	14	353	3	340	6.7e-99	327.6	COG2008	Threonine aldolase	342
2852595388	350	98.68	7	308	3	300	3.4e-108	357.7	COG3285	Eukaryotic-type DNA primase	299
2852595389	348	66.46	1	341	151	477	1.2e-74	248.4	COG1793	ATP-dependent DNA ligase	444
2852595390	357	67.89	1	349	150	483	1.6e-87	290.8	COG1793	ATP-dependent DNA ligase	444
2852595393	74	10.59	3	65	181	214	4.2e-03	12.8	COG0391	Archaeal 2-phospho-L-lactate transferase/Bacterial gluconeogenesis factor, CofD/UPF0052 family	323
2852595400	336	58.53	42	259	54	180	2.2e-21	72.6	COG5637	Uncharacterized membrane protein	217
2852595403	69	12.31	1	57	56	96	8.5e-01	5.2	COG4129	Uncharacterized membrane protein YgaE, UPF0421/DUF939 family	332
2852595404	337	89.25	1	335	10	308	3.5e-62	206.5	COG2334	Ser/Thr protein kinase RdoA involved in Cpx stress response, MazF antagonist	331
2852595405	433	98.21	1	433	5	442	9.2e-130	429.8	COG0160	4-aminobutyrate aminotransferase or related aminotransferase	447
2852595407	290	53.33	2	286	12	267	4.3e-76	253.4	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
2852595408	479	90.79	243	477	20	226	1.3e-76	253.4	COG0765	ABC-type amino acid transport system, permease component	222
2852595409	251	97.93	4	248	5	241	2.2e-99	328	COG1126	ABC-type polar amino acid transport system, ATPase component	240
2852595410	440	91.19	2	439	16	481	7.1e-77	254.7	COG0427	Acyl-CoA hydrolase	501
2852595411	401	96.91	1	401	2	377	1.2e-66	221.9	COG1748	Saccharopine dehydrogenase, NADP-dependent	389
2852595412	409	95.7	9	409	9	364	0.0e+00	447.7	COG0343	Queuine/archaeosine tRNA-ribosyltransferase	372
2852595414	301	97.29	27	301	7	293	2.7e-35	118.9	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852595415	166	14.53	7	99	66	91	1.2e+00	2.5	COG3134	Uncharacterized conserved protein YcfJ, contains glycine zipper 2TM domain	179
2852595415	166	25.14	93	165	66	110	1.2e+00	9	COG3134	Uncharacterized conserved protein YcfJ, contains glycine zipper 2TM domain	179
2852595421	152	96.08	1	148	6	152	1.2e-50	168.1	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
2852595423	319	98.21	2	276	4	277	2.5e-68	226.3	COG0287	Prephenate dehydrogenase	279
2852595424	205	93.16	12	205	13	189	1.4e-48	161.6	COG3554	Uncharacterized protein	190
2852595425	266	87.89	3	222	21	216	5.3e-53	176.1	COG1174	ABC-type proline/glycine betaine transport system, permease component	221
2852595426	227	91.03	1	213	17	219	2.8e-54	180.3	COG1174	ABC-type proline/glycine betaine transport system, permease component	221
2852595427	369	99.36	1	359	1	312	1.4e-111	369.3	COG1125	ABC-type proline/glycine betaine transport system, ATPase component	309
2852595428	313	98.67	3	305	5	300	3.1e-71	236.4	COG1732	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)	300
2852595429	134	86.73	36	133	11	95	3.4e-32	106.6	COG5416	Uncharacterized integral membrane protein	98
2852595430	305	91.86	31	305	19	289	6.0e-41	137.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852595431	341	97.55	1	336	6	324	5.3e-85	282	COG3173	Predicted  kinase, aminoglycoside phosphotransferase (APT) family	321
2852595432	202	90.91	1	199	4	193	2.5e-32	108.8	COG0406	Broad specificity phosphatase PhoE	208
2852595433	256	98.88	11	255	2	266	7.2e-61	202.6	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852595434	625	96.18	1	625	25	654	0.0e+00	953.3	COG2015	Alkyl sulfatase BDS1 and related hydrolases, metallo-beta-lactamase superfamily	655
2852595435	182	31.78	63	170	64	104	2.2e-04	17.3	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
2852595436	293	98.95	6	287	2	284	5.3e-39	130.6	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
2852595437	112	85	2	112	9	110	2.3e-40	133.5	COG1733	DNA-binding transcriptional regulator, HxlR family	120
2852595438	137	92.74	1	136	8	122	2.6e-15	52.7	COG3801	Uncharacterized protein	124
2852595439	167	95.35	1	167	3	166	9.1e-35	116.1	COG0622	Predicted phosphodiesterase	172
2852595440	186	68.02	23	165	25	141	6.8e-03	12.7	COG2318	Uncharacterized damage-inducible protein DinB (forms a four-helix bundle)	172
2852595441	231	95.33	123	226	3	104	6.5e-14	47.8	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
2852595442	184	86.02	16	183	14	173	2.4e-25	85.7	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2852595443	152	88.89	2	146	12	139	2.1e-20	69.8	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
2852595444	485	79.1	260	457	47	239	6.2e-32	106.7	COG2114	Adenylate cyclase, class 3	227
2852595445	452	77.46	254	450	46	234	2.1e-33	111.6	COG2114	Adenylate cyclase, class 3	227
2852595446	702	93.57	2	382	14	377	4.9e-81	269.3	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
2852595449	349	97.78	4	349	2	354	5.0e-104	344.5	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
2852595452	277	99.25	5	274	3	265	6.3e-69	228.8	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2852595453	368	98.31	20	368	3	352	3.7e-111	368.1	COG3424	Predicted naringenin-chalcone synthase	356
2852595454	166	94.77	1	166	5	167	1.5e-54	180.9	COG1755	Uncharacterized protein YpbQ, isoprenylcysteine carboxyl methyltransferase (ICMT) family	172
2852595455	314	93.77	1	308	2	302	2.1e-36	122.1	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2852595457	461	98.68	20	461	2	451	7.3e-121	400.7	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
2852595459	158	70.68	13	148	7	100	8.5e-17	57.9	COG1846	DNA-binding transcriptional regulator, MarR family	126
2852595460	326	100	1	322	1	331	8.4e-88	291.4	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2852595461	398	98.78	1	398	1	404	6.3e-85	282	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
2852595464	266	98.8	1	254	2	249	1.1e-91	303.4	COG1134	ABC-type polysaccharide/polyol phosphate transport system, ATPase component	249
2852595465	299	99.68	1	294	2	313	1.0e-56	188.9	COG1216	Glycosyltransferase, GT2 family	305
2852595466	276	97.36	11	276	8	265	6.1e-80	264.7	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
2852595467	172	66.67	4	166	62	187	4.7e-25	82.8	COG2020	Protein-S-isoprenylcysteine O-methyltransferase Ste14	187
2852595468	204	76.56	2	196	11	170	6.5e-18	62.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852595470	110	39.78	1	91	62	135	1.8e-16	57.4	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
2852595471	155	77.42	3	154	41	184	1.4e-33	113.1	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
2852595472	470	96.49	30	467	12	451	7.2e-101	334.5	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
2852595473	220	87.93	5	218	10	213	1.2e-12	44.2	COG0671	Membrane-associated phospholipid phosphatase	232
2852595474	136	92.09	6	136	9	136	2.4e-26	88.8	COG2246	Putative flippase GtrA (transmembrane translocase of bactoprenol-linked glucose)	139
2852595475	466	94.24	4	464	26	467	1.3e-60	202	COG0277	FAD/FMN-containing dehydrogenase	459
2852595476	260	93.58	7	259	7	254	4.0e-28	94.6	COG0300	Short-chain dehydrogenase	265
2852595481	303	76.92	23	300	26	225	9.3e-30	100.3	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2852595483	448	48.78	50	194	45	144	3.4e-06	22.4	COG3642	tRNA A-37 threonylcarbamoyl transferase component Bud32	204
2852595484	517	98.29	2	517	9	525	0.0e+00	628.2	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component	526
2852595485	1782	98.83	1521	1779	2	255	1.6e-68	226.2	COG3319	Thioesterase domain of type I polyketide synthase or non-ribosomal peptide synthetase	257
2852595485	1782	99.66	121	1349	4	1186	0.0e+00	1246.5	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
2852595486	630	96.83	14	621	12	561	1.8e-105	349.7	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2852595489	284	89.51	2	284	29	318	9.5e-64	212.1	COG0627	S-formylglutathione hydrolase FrmB	316
2852595490	350	96.3	4	335	11	322	1.3e-90	300.4	COG0627	S-formylglutathione hydrolase FrmB	316
2852595491	332	90.74	13	332	27	320	4.4e-82	272.4	COG0627	S-formylglutathione hydrolase FrmB	316
2852595493	318	97.93	22	315	6	289	6.3e-58	192.5	COG0382	4-hydroxybenzoate polyprenyltransferase	289
2852595494	174	64.66	12	172	64	213	1.1e-19	67.7	COG0671	Membrane-associated phospholipid phosphatase	232
2852595495	646	99.04	170	497	3	312	3.9e-73	242.7	COG1216	Glycosyltransferase, GT2 family	305
2852595496	401	99.47	4	384	1	372	0.0e+00	576.4	COG0562	UDP-galactopyranose mutase	374
2852595498	535	18.91	396	520	275	385	7.0e-69	59.4	COG5479	Uncharacterized conserved protein, contains LGFP repeats	556
2852595498	535	65.76	9	400	35	420	7.0e-69	175	COG5479	Uncharacterized conserved protein, contains LGFP repeats	556
2852595499	270	97.79	2	270	4	269	5.9e-64	212.9	COG0561	Hydroxymethylpyrimidine pyrophosphatase and other HAD family phosphatases	264
2852595500	254	81.23	15	231	48	259	1.6e-43	145.3	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
2852595501	258	85.82	2	232	34	257	8.9e-51	169	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
2852595503	520	96.6	1	264	8	263	3.4e-29	98.1	COG2220	L-ascorbate metabolism protein UlaG, beta-lactamase superfamily	258
2852595508	419	99.07	1	419	2	428	0.0e+00	502.8	COG0172	Seryl-tRNA synthetase	429
2852595509	473	55.56	193	252	21	65	9.5e-05	14.3	COG4892	Predicted heme/steroid binding protein	81
2852595510	116	91.18	1	116	10	133	2.9e-44	146.7	COG3824	Predicted Zn-dependent protease, minimal metalloprotease (MMP)-like domain	136
2852595512	228	92.34	1	220	2	194	1.3e-44	148.9	COG0406	Broad specificity phosphatase PhoE	208
2852595513	308	97.5	1	286	4	276	1.7e-83	276.5	COG0077	Prephenate dehydratase	279
2852595515	255	76.09	14	255	43	217	5.0e-19	65.3	COG1266	Membrane protease YdiL, CAAX protease family	226
2852595517	313	79.04	1	311	40	303	4.5e-62	207	COG1316	Anionic cell wall polymer biosynthesis enzyme,  LytR-Cps2A-Psr (LCP) family	307
2852595518	274	96.31	7	266	9	269	6.1e-56	186.4	COG0584	Glycerophosphoryl diester phosphodiesterase	257
2852595520	113	84.21	5	106	16	111	3.4e-27	91.1	COG0607	Rhodanese-related sulfurtransferase	110
2852595525	245	97.4	2	191	1	187	9.2e-59	195	COG2119	Putative Ca2+/H+ antiporter, TMEM165/GDT1 family	190
2852595526	132	67.69	28	129	21	108	6.0e-07	26.9	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2852595532	222	63.48	9	215	11	123	1.8e-13	47.2	COG4549	Uncharacterized protein YcnI	178
2852595533	168	96.85	1	124	3	125	5.3e-25	84.6	COG2372	Copper-binding protein CopC (methionine-rich)	127
2852595534	280	92.39	10	280	18	284	8.2e-28	94.2	COG1276	Putative copper export protein	289
2852595535	165	20.51	2	161	399	518	2.3e-02	10.5	COG2812	DNA polymerase III, gamma/tau subunits	515
2852595536	251	81.06	5	182	2	108	5.2e-28	93.6	COG0789	DNA-binding transcriptional regulator, MerR family	124
2852595537	160	75.94	1	160	11	171	3.5e-51	170.4	COG0684	Regulator of RNase E activity RraA	210
2852595538	491	97.76	1	447	8	443	0.0e+00	464.4	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
2852595539	213	92.34	5	213	11	203	3.0e-22	76.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852595540	400	98.66	6	356	2	370	1.5e-83	277.6	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
2852595541	347	98.35	109	347	2	239	5.6e-73	241.9	COG1387	Histidinol phosphatase or related hydrolase of the PHP family	237
2852595542	125	81.36	10	113	13	108	5.9e-13	45.7	COG0640	DNA-binding transcriptional regulator, ArsR family	110
2852595543	548	96.45	10	546	18	560	0.0e+00	441.8	COG0659	Sulfate permease or related transporter, MFS superfamily	554
2852595545	295	70.26	3	291	12	252	8.1e-58	192.5	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852595547	272	72.76	40	267	62	256	6.2e-28	94.2	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
2852595548	488	99.34	23	476	2	456	0.0e+00	564.6	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
2852595549	1527	98.03	1212	1520	3	300	8.7e-112	369.7	COG0070	Glutamate synthase domain 3	301
2852595549	1527	99.18	712	1206	3	487	0.0e+00	709.4	COG0069	Glutamate synthase domain 2	485
2852595549	1527	100	6	390	1	372	0.0e+00	500.1	COG0067	Glutamate synthase domain 1	371
2852595550	682	89.74	1	673	72	727	0.0e+00	728.8	COG2217	Cation transport ATPase	713
2852595551	268	63.83	152	268	46	135	4.9e-13	44.8	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
2852595552	436	93.03	5	436	21	434	5.1e-86	285.6	COG0038	H+/Cl- antiporter ClcA	443
2852595553	354	55.02	8	158	72	186	4.9e-32	47.2	COG2140	Oxalate decarboxylase/archaeal phosphoglucose isomerase, cupin superfamily	209
2852595553	354	58.37	167	334	81	202	4.9e-32	58.6	COG2140	Oxalate decarboxylase/archaeal phosphoglucose isomerase, cupin superfamily	209
2852595554	185	96.82	1	157	6	157	2.8e-37	124.6	COG0783	DNA-binding ferritin-like protein (oxidative damage protectant)	156
2852595555	301	90.31	15	294	24	284	3.9e-37	124.7	COG0122	3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase	285
2852595556	124	84.09	1	124	16	126	5.7e-43	142.3	COG2343	Uncharacterized conserved protein, DUF427 family	132
2852595558	460	97.16	27	420	4	380	7.2e-56	186.6	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2852595561	272	84	2	269	8	259	3.0e-48	161	COG3315	O-Methyltransferase involved in polyketide biosynthesis	297
2852595562	337	97.2	4	329	5	316	1.5e-54	182.1	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2852595564	282	96.61	27	276	6	290	1.0e-21	72.6	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852595566	152	92.2	3	146	8	137	4.3e-59	194.7	COG0229	Peptide methionine sulfoxide reductase MsrB	140
2852595567	177	90.23	1	162	5	161	8.3e-62	204.7	COG0225	Peptide methionine sulfoxide reductase MsrA	174
2852595568	445	96.2	15	444	16	420	2.1e-88	293.5	COG2124	Cytochrome P450	411
2852595569	199	90.91	4	199	15	204	3.1e-19	67	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852595570	189	84.69	7	189	6	182	2.9e-16	57.2	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852595571	215	24.55	8	76	40	93	3.5e-10	24.8	COG4122	Predicted O-methyltransferase YrrM	219
2852595571	215	32.73	96	194	101	172	3.5e-10	9.6	COG4122	Predicted O-methyltransferase YrrM	219
2852595572	867	73.75	795	865	17	75	2.6e-17	57.4	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2852595573	442	98.81	10	441	5	420	3.5e-95	315.8	COG2124	Cytochrome P450	411
2852595575	243	44.09	1	226	52	174	5.4e-16	56	COG0500	SAM-dependent methyltransferase	257
2852595576	408	95.84	1	407	15	406	3.2e-42	142.1	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2852595579	161	78.38	1	158	11	155	1.2e-28	96.5	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
2852595584	212	97.14	1	203	1	204	7.8e-61	201.9	COG2808	Predicted FMN-binding regulatory protein PaiB	209
2852595586	460	96.49	2	404	9	393	4.3e-93	308.7	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852595587	258	91.75	1	256	10	276	2.4e-60	200.6	COG2513	2-Methylisocitrate lyase and related enzymes, PEP mutase family	289
2852595588	250	99.63	1	248	1	267	1.3e-62	208.4	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852595590	392	99.72	1	392	2	353	7.2e-100	330.6	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
2852595591	486	12.14	398	486	508	579	1.7e-81	58.3	COG1982	Arginine/lysine/ornithine decarboxylase	557
2852595591	486	73.19	1	399	5	438	1.7e-81	210.9	COG1982	Arginine/lysine/ornithine decarboxylase	557
2852595594	141	6.55	1	99	5	33	6.3e-03	12.6	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2852595596	183	85.44	1	182	6	181	3.6e-43	144.2	COG1335	Nicotinamidase-related amidase	205
2852595597	271	98.87	8	262	4	265	6.2e-66	218.9	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2852595598	718	98.15	8	718	8	698	0.0e+00	921.5	COG1523	Pullulanase/glycogen debranching enzyme	697
2852595601	186	93.3	1	186	4	198	1.7e-15	54.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852595603	258	99.25	2	251	2	267	2.0e-71	237.2	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852595605	150	80.45	6	144	21	127	2.4e-17	59.7	COG1846	DNA-binding transcriptional regulator, MarR family	126
2852595606	268	77.12	1	265	2	237	1.7e-85	283.6	COG1131	ABC-type multidrug transport system, ATPase component	293
2852595607	276	69.62	50	274	84	287	2.9e-23	78.8	COG0842	ABC-type multidrug transport system, permease component	286
2852595608	629	93.6	23	592	7	518	1.1e-48	162.9	COG1807	4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family	535
2852595609	162	90.11	2	152	12	175	7.4e-29	89.7	COG3059	Uncharacterized membrane protein YkgB	182
2852595612	440	97.82	18	440	2	450	0.0e+00	452.6	COG3281	Predicted trehalose synthase	438
2852595613	592	99.03	45	557	1	512	1.2e-127	423.8	COG0366	Glycosidase	505
2852595614	152	52.17	96	148	4	39	1.7e-02	10.1	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
2852595616	266	96.36	27	266	5	242	7.1e-19	64.4	COG0748	Putative heme iron utilization protein	245
2852595617	191	79.31	13	189	17	177	5.8e-38	127	COG0461	Orotate phosphoribosyltransferase	201
2852595618	347	98.3	2	346	5	351	3.7e-117	388	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2852595619	267	94.38	1	255	10	261	7.1e-40	133.4	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
2852595620	280	97.16	2	280	9	282	3.7e-78	259.2	COG4132	ABC-type uncharacterized transport system, permease component	282
2852595621	375	85.71	80	372	1	258	1.1e-38	130	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
2852595623	137	37.35	3	117	17	78	4.5e-05	20	COG3467	Nitroimidazol reductase NimA or a related FMN-containing flavoprotein, pyridoxamine 5'-phosphate oxidase superfamily	166
2852595625	730	98.08	13	730	6	720	0.0e+00	588.3	COG0480	Translation elongation factor EF-G, a GTPase	697
2852595628	180	48.15	7	137	41	118	2.8e-06	24.2	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2852595629	445	96.53	38	443	13	374	4.2e-50	167.4	COG4585	Signal transduction histidine kinase	365
2852595630	200	93.55	3	193	7	180	2.7e-41	137.8	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2852595633	527	26.22	90	515	202	513	3.5e-35	116.9	COG4934	Serine protease, subtilase family	1174
2852595635	544	99.81	12	542	2	527	0.0e+00	504	COG1620	L-lactate permease	522
2852595636	118	92.31	6	118	8	115	8.2e-21	70.4	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
2852595637	299	85.47	169	281	2	101	7.3e-25	83	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
2852595638	129	93.16	1	114	5	113	6.2e-18	61.2	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
2852595639	143	91.1	7	142	11	143	6.7e-27	90.2	COG2172	Anti-sigma regulatory factor (Ser/Thr protein kinase)	146
2852595640	208	39.95	6	181	165	311	3.7e-06	22.3	COG2208	Serine phosphatase RsbU, regulator of sigma subunit	367
2852595641	728	57.44	6	220	102	240	1.5e-13	46.1	COG2202	PAS domain	232
2852595641	728	64.67	341	602	125	362	1.0e-34	116.3	COG2208	Serine phosphatase RsbU, regulator of sigma subunit	367
2852595641	728	79.45	611	726	18	133	4.2e-17	57.3	COG2172	Anti-sigma regulatory factor (Ser/Thr protein kinase)	146
2852595642	140	90.41	14	140	10	141	8.7e-14	46.4	COG2172	Anti-sigma regulatory factor (Ser/Thr protein kinase)	146
2852595643	103	73.5	7	103	16	101	1.2e-12	44.1	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
2852595645	362	93.38	2	362	26	392	1.4e-111	369.3	COG0153	Galactokinase	390
2852595646	363	29.33	2	101	143	242	1.4e-87	22.2	COG1085	Galactose-1-phosphate uridylyltransferase	338
2852595646	363	95.6	41	363	7	332	1.4e-87	273.9	COG1085	Galactose-1-phosphate uridylyltransferase	338
2852595647	259	99.21	1	256	1	252	5.9e-68	225.7	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
2852595648	582	96.8	30	558	5	488	1.5e-57	191.6	COG0591	Na+/proline symporter	493
2852595649	94	37.91	5	89	17	85	3.0e-03	13.6	COG2245	Uncharacterized membrane protein	182
2852595650	305	82.39	14	285	43	290	4.6e-12	38.5	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2852595654	87	12.09	2	65	164	214	2.3e-02	10.1	COG4653	Predicted phage phi-C31 gp36 major capsid-like protein	422
2852595655	214	94.26	5	213	8	204	5.2e-19	66.2	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852595657	243	97.08	14	242	5	237	1.4e-79	256.9	COG4312	Predicted dithiol-disulfide oxidoreductase, DUF899 family	247
2852595659	421	98.56	13	412	6	416	1.5e-61	205.4	COG1721	Uncharacterized conserved protein, DUF58 family, contains vWF domain	416
2852595660	323	97.27	4	320	9	329	1.2e-105	349.7	COG0714	MoxR-like ATPase	329
2852595663	221	71.36	10	218	15	171	9.4e-38	126.2	COG4122	Predicted O-methyltransferase YrrM	219
2852595664	239	92.83	2	239	13	258	2.9e-41	138	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2852595666	388	82.39	66	385	46	307	2.8e-46	154.8	COG0657	Acetyl esterase/lipase	312
2852595667	633	97.77	2	633	15	627	0.0e+00	765.8	COG3158	K+ transporter	627
2852595669	238	78.73	6	231	3	213	3.5e-20	66.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852595670	315	88.71	2	190	13	177	2.8e-42	140.5	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2852595671	159	89.21	34	158	13	136	3.6e-08	29	COG2246	Putative flippase GtrA (transmembrane translocase of bactoprenol-linked glucose)	139
2852595672	286	90.79	48	264	16	222	2.1e-44	148.7	COG0705	Membrane associated serine protease, rhomboid family	228
2852595673	135	95.21	10	133	6	144	3.5e-07	27.2	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2852595674	122	27.11	3	98	11	84	7.6e-04	15.3	COG2514	Catechol-2,3-dioxygenase	265
2852595677	143	63.86	3	142	18	123	1.5e-08	31.2	COG3467	Nitroimidazol reductase NimA or a related FMN-containing flavoprotein, pyridoxamine 5'-phosphate oxidase superfamily	166
2852595679	415	95.3	1	411	2	386	2.9e-61	204.4	COG1680	CubicO group peptidase, beta-lactamase class C family	390
2852595680	120	92.31	9	120	6	113	7.1e-13	44.8	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
2852595681	131	86.99	1	126	10	136	3.2e-14	48.2	COG2172	Anti-sigma regulatory factor (Ser/Thr protein kinase)	146
2852595682	149	88.72	10	145	8	125	1.7e-24	82.6	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2852595683	524	84.77	7	519	57	390	4.5e-55	183.2	COG0642	Signal transduction histidine kinase	336
2852595684	402	94.74	18	153	6	131	5.2e-19	64.3	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2852595686	538	95.56	8	441	9	395	1.1e-93	310.3	COG1290	Cytochrome b subunit of the bc complex	381
2852595687	374	84.15	1	332	4	348	4.8e-23	76.1	COG1252	NADH dehydrogenase, FAD-containing subunit	405
2852595689	566	88.06	223	508	2	237	6.0e-67	222.1	COG1018	Ferredoxin-NADP reductase	266
2852595689	566	96.73	3	213	4	210	2.2e-58	193.5	COG2258	Uncharacterized conserved protein YiiM, contains MOSC domain	210
2852595690	420	87.45	8	415	16	447	1.6e-81	268.8	COG2272	Carboxylesterase type B	491
2852595691	175	72.26	35	169	32	130	1.5e-11	40.7	COG1765	Uncharacterized OsmC-related protein	137
2852595692	1298	96.44	18	959	24	863	0.0e+00	944	COG1643	HrpA-like RNA helicase	845
2852595694	70	8.73	20	70	352	397	8.0e-03	11.3	COG3511	Phospholipase C	527
2852595697	484	99.2	3	484	5	497	0.0e+00	543.4	COG0397	Uncharacterized conserved protein YdiU, UPF0061 family	488
2852595698	305	98.25	26	290	1	280	7.3e-72	238.4	COG2301	Citrate lyase beta subunit	283
2852595699	251	31.49	3	149	45	141	2.6e-11	20.5	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
2852595699	251	31.49	136	251	209	305	2.6e-11	18.3	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
2852595701	208	87.64	125	208	3	80	4.6e-03	13.2	COG1343	CRISPR/Cas system-associated endoribonuclease Cas2	89
2852595703	136	64.89	2	119	32	116	2.7e-15	52.8	COG1917	Cupin domain protein related to quercetin dioxygenase	131
2852595704	240	98.88	1	238	2	266	5.1e-68	226	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852595705	183	89.78	3	183	13	179	6.4e-49	162.6	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2852595706	931	70	865	928	15	70	5.8e-17	56.2	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2852595707	251	85.14	1	247	1	235	1.6e-29	99.6	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
2852595710	390	99.04	1	384	3	413	9.0e-99	327.3	COG4941	Predicted RNA polymerase sigma factor, contains C-terminal TPR domain	415
2852595711	137	83.74	16	136	16	118	1.2e-18	63.7	COG3795	Uncharacterized conserved protein	123
2852595712	276	58.31	4	232	19	218	4.8e-59	196.3	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852595713	397	97.95	124	395	4	290	1.8e-47	157.9	COG1408	Predicted phosphohydrolase, MPP superfamily	284
2852595714	214	79.41	7	198	5	139	1.6e-20	69.7	COG0262	Dihydrofolate reductase	167
2852595715	775	98.34	5	772	9	777	0.0e+00	965.3	COG2183	Transcriptional accessory protein Tex/SPT6	780
2852595716	245	75.78	3	245	65	283	1.3e-15	53.8	COG5473	Uncharacterized membrane protein	290
2852595717	365	99.71	1	349	1	349	0.0e+00	434.2	COG3839	ABC-type sugar transport system, ATPase component	338
2852595718	304	95.05	23	303	15	283	7.0e-85	281.2	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
2852595719	297	95.97	6	295	7	292	1.7e-85	283.3	COG1175	ABC-type sugar transport system, permease component	295
2852595720	426	98.42	3	426	6	441	4.5e-77	256.8	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2852595721	436	98.64	1	431	3	438	1.0e-114	380.2	COG1486	Alpha-galactosidase/6-phospho-beta-glucosidase, family 4 of glycosyl hydrolase	442
2852595722	320	96.68	7	300	7	297	4.7e-20	68.3	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2852595723	323	96.03	1	311	5	294	1.6e-48	162.1	COG2971	BadF-type ATPase, related to human N-acetylglucosamine kinase	301
2852595724	388	98.82	18	373	5	340	8.9e-63	208.8	COG2222	Fructoselysine-6-P-deglycase FrlB and related proteins with duplicated sugar isomerase (SIS) domain	340
2852595725	438	98.83	11	436	3	423	0.0e+00	619.7	COG4573	Tagatose-1,6-bisphosphate aldolase non-catalytic subunit AgaZ/GatZ	426
2852595726	295	97.57	1	287	2	282	4.8e-69	229.3	COG0191	Fructose/tagatose bisphosphate aldolase	286
2852595727	259	98.82	3	257	3	253	7.1e-67	222.1	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
2852595729	880	87.5	794	873	8	77	3.9e-22	73.2	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2852595734	331	64.71	1	331	60	411	7.7e-92	305.4	COG5297	Cellulase/cellobiase CelA1	544
2852595735	448	89.59	74	448	32	358	1.5e-82	273.9	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2852595736	179	38.67	3	160	96	194	4.2e-02	9.3	COG1989	Prepilin signal peptidase PulO (type II secretory pathway) or related peptidase	254
2852595737	479	94.09	13	188	4	178	9.3e-35	116	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2852595739	347	77.5	281	347	18	79	1.7e-17	57.9	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2852595739	347	84.75	8	271	40	289	1.6e-28	96.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852595740	223	49.79	34	201	53	171	2.9e-15	52.4	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
2852595741	343	61.01	189	307	10	106	5.0e-30	63.8	COG2030	Acyl dehydratase	159
2852595741	343	87.42	1	150	14	152	5.0e-30	40.1	COG2030	Acyl dehydratase	159
2852595744	932	98.62	1	932	6	934	0.0e+00	974	COG2409	Uncharacterized membrane protein YdfJ, MMPL/SSD domain	937
2852595746	329	85.05	2	328	3	275	3.5e-40	134.8	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2852595749	692	77.71	1	139	6	127	2.3e-04	17.1	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
2852595749	692	94.89	187	689	17	555	1.2e-84	280.9	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2852595750	474	48.04	273	473	17	200	1.7e-38	28.5	COG0477	MFS family permease	338
2852595750	474	82.77	16	311	5	321	1.7e-38	105.4	COG0477	MFS family permease	338
2852595753	416	99.03	10	416	3	412	7.0e-105	347.5	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
2852595757	329	94.72	2	288	8	294	1.7e-35	118.9	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
2852595758	201	91.39	1	201	7	197	1.3e-17	61.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852595759	264	99.25	16	261	2	267	3.7e-55	183.8	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852595761	157	84.85	39	155	1	112	2.3e-26	88.8	COG0789	DNA-binding transcriptional regulator, MerR family	124
2852595762	290	92.16	4	267	5	251	1.9e-48	161.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852595764	147	90.85	1	147	12	150	5.9e-32	107.4	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
2852595765	329	61.03	196	315	3	85	2.9e-03	13.5	COG3631	Ketosteroid isomerase-related protein	133
2852595765	329	85.48	6	194	15	173	5.1e-43	143.5	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2852595766	246	96.67	1	239	7	238	4.1e-74	245.7	COG4312	Predicted dithiol-disulfide oxidoreductase, DUF899 family	247
2852595769	294	44.4	52	271	74	192	2.7e-25	84.2	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
2852595770	377	92.01	8	373	3	336	1.2e-98	327.2	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
2852595771	491	95.76	9	463	11	439	5.9e-72	238.9	COG1457	Purine-cytosine permease or related protein	442
2852595772	376	93.02	7	366	22	354	1.6e-92	306.6	COG0252	L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D	351
2852595773	187	55.38	11	125	2	73	2.5e-15	53.8	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2852595774	223	70.08	5	217	49	233	1.0e-30	103.2	COG3665	Uncharacterized conserved protein YcgI, DUF1989 family	264
2852595776	155	66.41	1	117	23	109	1.7e-15	53.5	COG1917	Cupin domain protein related to quercetin dioxygenase	131
2852595777	290	83.7	6	276	3	233	3.6e-46	154.2	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
2852595778	215	72.25	5	194	5	155	1.0e-17	62	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852595781	109	83.33	1	106	17	116	3.1e-32	107.2	COG1733	DNA-binding transcriptional regulator, HxlR family	120
2852595782	277	93.48	1	260	2	259	6.5e-34	114	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
2852595783	877	99.77	23	876	1	435	0.0e+00	698.5	COG0305	Replicative DNA helicase	435
2852595784	151	98.65	1	151	1	146	1.0e-48	161.8	COG0359	Ribosomal protein L9	148
2852595785	87	97.47	1	80	3	79	1.4e-27	92.6	COG0238	Ribosomal protein S18	75
2852595786	169	98.83	2	169	3	171	4.6e-47	157	COG0629	Single-stranded DNA-binding protein	167
2852595787	96	83.04	2	96	2	94	2.6e-34	114	COG0360	Ribosomal protein S6	112
2852595788	437	85.66	251	437	23	231	3.5e-34	114.1	COG2114	Adenylate cyclase, class 3	227
2852595789	450	79.51	270	450	38	231	1.5e-33	112.9	COG2114	Adenylate cyclase, class 3	227
2852595790	51	7.67	1	47	296	329	9.2e-01	4.9	COG1030	Membrane-bound serine protease (ClpP class)	436
2852595791	546	93.87	18	535	3	507	0.0e+00	543.3	COG5650	Uncharacterized membrane protein	536
2852595792	762	89.9	46	753	15	655	0.0e+00	587.9	COG0744	Membrane carboxypeptidase (penicillin-binding protein)	661
2852595795	184	67.88	1	180	9	101	8.7e-25	83.1	COG1695	DNA-binding transcriptional regulator, PadR family	138
2852595796	358	99.47	2	358	3	377	0.0e+00	515.8	COG1260	Myo-inositol-1-phosphate synthase	362
2852595797	299	96.27	23	299	6	289	9.3e-33	110.6	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852595798	518	89.01	1	398	7	403	9.3e-61	202.2	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
2852595799	689	98.72	33	689	5	619	0.0e+00	592.1	COG3211	Secreted phosphatase, PhoX family	616
2852595800	262	63.56	3	231	11	228	3.1e-42	140.5	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852595801	234	90.52	1	215	14	223	1.2e-32	109.7	COG1802	DNA-binding transcriptional regulator, GntR family	230
2852595802	588	89.05	4	305	21	272	9.1e-40	132.7	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2852595802	588	93.86	335	571	13	226	1.7e-61	203.7	COG0765	ABC-type amino acid transport system, permease component	222
2852595803	230	95.45	1	230	11	241	1.5e-96	318.7	COG1126	ABC-type polar amino acid transport system, ATPase component	240
2852595804	147	84.21	10	146	13	124	6.7e-27	90.5	COG1846	DNA-binding transcriptional regulator, MarR family	126
2852595805	271	49.79	24	191	43	161	4.1e-16	55.1	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
2852595807	221	95.12	1	221	8	241	3.9e-47	157.5	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
2852595809	946	99.88	12	946	2	823	0.0e+00	997.3	COG0495	Leucyl-tRNA synthetase	814
2852595811	117	29.24	1	101	155	242	7.7e-02	8.9	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2852595812	201	96.91	7	199	3	190	3.2e-55	183.1	COG1678	Putative transcriptional regulator, AlgH/UPF0301 family	194
2852595813	427	85.12	17	416	27	352	6.1e-05	17.3	COG0477	MFS family permease	338
2852595815	1103	79.51	31	262	44	237	1.7e-41	137.6	COG2114	Adenylate cyclase, class 3	227
2852595817	478	97.11	16	464	10	412	1.2e-106	353.9	COG0617	tRNA nucleotidyltransferase/poly(A) polymerase	412
2852595818	252	74.42	53	210	20	147	1.9e-20	69.7	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2852595820	1225	98.26	54	580	3	511	5.5e-130	430.5	COG0728	Peptidoglycan biosynthesis protein MviN/MurJ, putative lipid II flippase	518
2852595821	196	95.7	10	183	2	179	2.7e-45	150.8	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2852595823	326	99.35	5	312	2	306	2.4e-124	410.8	COG0492	Thioredoxin reductase	305
2852595824	111	35.08	1	111	22	128	4.2e-31	105.4	COG3118	Negative regulator of GroEL, contains thioredoxin-like and TPR-like domains	304
2852595825	398	73.31	63	368	69	263	1.2e-51	172.3	COG0860	N-acetylmuramoyl-L-alanine amidase	231
2852595827	330	98.86	59	321	4	264	2.0e-76	253.9	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
2852595828	319	97.35	58	315	3	259	1.0e-82	274.3	COG1192	Cellulose biosynthesis protein BcsQ	259
2852595829	230	93.49	5	215	12	212	1.2e-57	191.2	COG0357	16S rRNA G527 N7-methylase RsmG (former glucose-inhibited division protein B)	215
2852595830	190	65	3	190	76	218	1.5e-52	175.1	COG1847	Predicted RNA-binding protein Jag, conains KH and R3H domains	208
2852595831	359	78.41	2	305	67	313	1.4e-78	261	COG0706	Membrane protein insertase Oxa1/YidC/SpoIIIJ, required for the localization of integral membrane proteins	314
2852595832	97	81.52	1	90	7	81	2.2e-31	104	COG0759	Membrane-anchored protein YidD, putatitve component of membrane protein insertase Oxa1/YidC/SpoIIIJ	92
2852595833	114	90.68	1	114	8	114	1.3e-22	76.6	COG0594	RNase P protein component	117
2852595834	47	97.73	4	47	2	44	5.0e-20	67.8	COG0230	Ribosomal protein L34	44
2852595835	500	99.77	13	492	1	432	0.0e+00	565.4	COG0593	Chromosomal replication initiation ATPase DnaA	408
2852595836	397	100	11	395	1	365	5.2e-101	335	COG0592	DNA polymerase III sliding clamp (beta) subunit, PCNA homolog	364
2852595837	297	99.33	1	294	1	298	2.0e-107	355.1	COG1023	6-phosphogluconate dehydrogenase (decarboxylating)	300
2852595838	386	96.42	1	380	2	351	1.8e-112	372.4	COG1195	Recombinational DNA repair ATPase RecF	363
2852595839	188	91.24	7	188	18	194	5.9e-53	176.2	COG5512	Predicted  nucleic acid-binding protein, contains Zn-ribbon domain (includes truncated derivatives)	194
2852595840	675	99.84	7	675	2	641	0.0e+00	933.7	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
2852595841	829	99.51	3	818	4	812	0.0e+00	1172.6	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
2852595848	85	16.49	6	83	104	151	2.0e-02	10.8	COG1426	Cytoskeletal protein RodZ, contains Xre-like HTH and DUF4115 domains	284
2852595849	450	26.91	4	118	52	125	1.2e-118	16	COG1760	L-serine deaminase	262
2852595849	450	100	170	446	1	275	1.2e-118	376	COG1760	L-serine deaminase	262
2852595851	175	98.73	9	175	1	155	5.7e-57	188.7	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
2852595854	249	92.71	4	246	19	247	1.3e-63	211.1	COG3879	Uncharacterized conserved protein YlxW, UPF0749 family	247
2852595855	221	98.43	1	192	2	189	7.2e-71	234	COG0512	Anthranilate/para-aminobenzoate synthase component II	191
2852595856	626	76.81	9	485	2	362	6.2e-71	236	COG0515	Serine/threonine protein kinase	384
2852595857	437	64.89	11	394	2	306	3.5e-62	207.4	COG0515	Serine/threonine protein kinase	384
2852595858	491	10.13	1	70	17	80	3.6e-91	1.6	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
2852595858	491	71.68	60	490	170	622	3.6e-91	299.8	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
2852595859	469	95.81	65	452	10	375	2.3e-100	332.1	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
2852595860	514	94.85	1	266	6	263	8.1e-70	231.5	COG0631	Serine/threonine protein phosphatase PrpC	262
2852595861	155	78.2	1	155	2	166	1.4e-23	79.8	COG1716	Forkhead associated (FHA) domain, binds pSer, pThr, pTyr	191
2852595865	196	91.39	4	196	12	202	5.9e-18	62.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852595866	749	93.83	5	745	47	806	5.7e-109	361.9	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2852595867	165	61.38	10	115	8	96	7.1e-13	44.6	COG3871	General stress protein 26 (function unknown)	145
2852595870	110	84.85	7	97	13	96	8.1e-18	60.9	COG2388	Predicted acetyltransferase, GNAT superfamily	99
2852595871	321	92.86	22	291	18	277	5.0e-68	226	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
2852595872	719	86.68	352	713	53	410	1.0e-41	140	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
2852595875	165	93.23	23	154	4	127	1.8e-24	82.7	COG1846	DNA-binding transcriptional regulator, MarR family	126
2852595876	511	95.44	1	509	14	515	0.0e+00	451.3	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component	526
2852595878	243	39.23	188	243	2	52	1.0e-07	14.4	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2852595878	243	40.77	20	111	3	55	1.0e-07	15.9	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2852595879	480	93.98	225	480	3	252	5.3e-44	147.2	COG0455	MinD-like ATPase involved in chromosome partitioning or flagellar assembly	262
2852595882	270	52.2	3	253	19	314	9.4e-28	93.8	COG1404	Serine protease, subtilisin family	508
2852595883	85	96.63	1	85	1	86	5.0e-17	58.4	COG1925	Phosphotransferase system, HPr and related phosphotransfer proteins	88
2852595884	669	89.34	169	287	2	110	1.5e-36	121.1	COG1445	Phosphotransferase system fructose-specific component IIB	122
2852595884	669	92.76	5	152	8	148	1.1e-29	99	COG1762	Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)	152
2852595884	669	96.8	299	663	2	334	3.3e-115	380.8	COG1299	Phosphotransferase system, fructose-specific IIC component	343
2852595885	326	97.74	1	318	2	304	3.3e-74	246	COG1105	Fructose-1-phosphate kinase or kinase (PfkB)	310
2852595886	255	99.21	1	255	1	252	1.2e-75	250.9	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
2852595887	566	98.26	15	564	2	565	0.0e+00	526.5	COG1080	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria)	574
2852595888	324	98.57	20	310	4	279	4.7e-79	262.3	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
2852595889	62	85.07	1	61	1	57	1.1e-12	44.3	COG3237	Uncharacterized conserved protein YjbJ, UPF0337 family	67
2852595890	275	75.97	119	227	28	125	1.4e-02	11.3	COG2149	Uncharacterized membrane protein YidH, DUF202 family	120
2852595891	397	94.39	1	393	5	391	3.2e-84	279.6	COG1252	NADH dehydrogenase, FAD-containing subunit	405
2852595892	703	76.82	8	586	9	535	3.6e-15	43.7	COG1289	Uncharacterized membrane protein YccC	674
2852595893	188	71.29	6	187	20	168	2.4e-09	33.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852595894	244	79.9	38	236	8	174	5.3e-20	69.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852595895	318	94.67	9	313	2	285	7.6e-92	304.1	COG3315	O-Methyltransferase involved in polyketide biosynthesis	297
2852595896	308	97	4	307	2	292	1.5e-98	326	COG3315	O-Methyltransferase involved in polyketide biosynthesis	297
2852595897	617	96.64	24	617	19	564	0.0e+00	449	COG2936	Predicted acyl esterase	563
2852595898	472	92.9	2	450	33	477	9.1e-116	383.6	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2852595899	287	93.66	3	248	4	254	6.7e-49	163.1	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852595900	320	100	1	320	1	331	3.2e-70	233.6	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2852595901	231	89.18	1	227	2	207	3.3e-25	85.8	COG1011	FMN phosphatase YigB, HAD superfamily	229
2852595902	161	83.75	1	158	6	139	1.2e-15	54.4	COG2839	Uncharacterized conserved protein YqgC, DUF456 family	160
2852595903	63	85.71	1	60	1	54	5.7e-22	74.1	COG2906	Bacterioferritin-associated ferredoxin	63
2852595905	249	87.2	2	244	23	240	1.8e-38	128.8	COG2365	Protein tyrosine/serine phosphatase	249
2852595906	410	99.25	1	403	1	396	4.9e-99	328.7	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852595907	153	92.21	1	150	2	143	2.5e-65	215.6	COG3558	Uncharacterized conserved protein, nuclear transport factor 2 (NTF2) superfamily	154
2852595908	546	52.48	283	527	8	208	4.2e-45	27.9	COG0477	MFS family permease	338
2852595908	546	83.29	29	313	4	322	4.2e-45	126.9	COG0477	MFS family permease	338
2852595909	279	61.92	2	175	14	161	6.1e-24	80.7	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
2852595912	285	11.08	224	282	287	324	4.4e-53	12.1	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852595912	285	58.89	3	232	19	220	4.4e-53	167.9	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852595914	220	99.05	13	220	2	210	5.4e-56	186	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2852595915	398	87.2	14	392	48	374	1.4e-48	161.8	COG4585	Signal transduction histidine kinase	365
2852595916	458	98.57	25	450	5	419	1.6e-84	280.7	COG2124	Cytochrome P450	411
2852595918	379	96.74	4	379	7	392	1.1e-118	393.3	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852595919	478	99.15	1	472	4	469	0.0e+00	694.7	COG1282	NAD/NADP transhydrogenase beta subunit	463
2852595920	506	30.85	372	506	89	200	0.0e+00	50.4	COG3288	NAD/NADP transhydrogenase alpha subunit	356
2852595920	506	99.72	2	362	2	363	0.0e+00	498.7	COG3288	NAD/NADP transhydrogenase alpha subunit	356
2852595921	287	96.51	23	287	8	256	6.6e-70	231.9	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2852595922	340	90.72	1	333	15	317	5.6e-72	239.1	COG4521	ABC-type taurine transport system, periplasmic component	334
2852595923	259	97.21	6	259	3	246	7.8e-82	271.1	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2852595925	218	91.87	1	201	12	203	5.4e-23	79.2	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852595926	588	96.99	17	460	8	394	7.3e-93	308.5	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852595927	340	97.81	14	336	7	318	8.2e-70	231.9	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2852595929	558	98.41	1	501	4	499	0.0e+00	627.6	COG3333	TctA family transporter	504
2852595930	226	92.95	1	226	9	232	4.7e-58	192.9	COG2186	DNA-binding transcriptional regulator, FadR family	241
2852595931	373	97.32	3	369	3	365	2.1e-92	306.3	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
2852595932	284	80.99	3	278	36	312	4.0e-46	154	COG0668	Small-conductance mechanosensitive channel	316
2852595933	368	100	1	367	1	366	1.4e-116	386.2	COG1062	Zn-dependent alcohol dehydrogenase	366
2852595934	152	96.4	9	144	3	136	8.6e-34	113	COG0824	Acyl-CoA thioesterase FadM	137
2852595935	147	97.26	1	147	1	142	1.6e-07	27.5	COG2867	Ribosome association toxin PasT (RatA) of the RatAB toxin-antitoxin module	146
2852595937	230	94.4	5	227	7	225	3.4e-48	160.4	COG1802	DNA-binding transcriptional regulator, GntR family	230
2852595938	546	96.48	10	526	10	557	3.4e-128	424.8	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2852595939	264	95.88	2	262	11	266	2.1e-81	269.4	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
2852595940	289	96.63	7	283	9	266	2.1e-79	262.9	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
2852595941	425	98.11	1	352	8	370	3.3e-86	286.2	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852595942	343	91.35	1	343	11	348	1.3e-90	300.8	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852595943	524	95.68	6	359	15	368	6.4e-78	258.6	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852595944	552	96.76	7	381	8	365	5.1e-94	311.6	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852595945	382	97.3	7	379	8	367	4.0e-91	302.3	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852595946	525	99.19	1	364	3	369	4.6e-81	269.2	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852595948	325	71.02	12	202	5	129	1.8e-10	36.8	COG1714	Uncharacterized membrane protein YckC, RDD family	172
2852595951	230	94.69	5	228	7	220	1.0e-22	77.1	COG3619	Uncharacterized membrane protein YoaK, UPF0700 family	226
2852595952	276	94.78	1	254	6	259	1.2e-50	169.1	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852595953	259	85.31	1	253	42	285	3.2e-51	170.8	COG3001	Fructosamine-3-kinase	286
2852595957	94	95.12	3	87	3	80	3.5e-17	58.8	COG2261	Uncharacterized membrane protein YeaQ/YmgE, transglycosylase-associated protein family	82
2852595958	425	96.85	2	425	11	410	2.9e-49	163.7	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
2852595959	253	87.86	5	251	3	248	3.0e-53	177.6	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
2852595960	147	88.72	10	146	10	127	1.8e-18	63	COG1846	DNA-binding transcriptional regulator, MarR family	126
2852595961	374	100	1	369	1	366	3.9e-119	394.6	COG1062	Zn-dependent alcohol dehydrogenase	366
2852595962	293	57.36	180	280	48	121	1.7e-07	27.2	COG2852	Very-short-patch-repair endonuclease	129
2852595963	323	56.92	195	297	5	78	3.1e-03	10.7	COG4308	Limonene-1,2-epoxide hydrolase	130
2852595963	323	85.48	4	194	17	175	5.7e-49	162.5	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2852595964	279	96.43	1	279	6	302	1.8e-79	263.5	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
2852595965	317	31.17	63	292	48	143	1.6e-02	6.6	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
2852595968	223	95	2	221	11	219	4.5e-57	189.4	COG4122	Predicted O-methyltransferase YrrM	219
2852595970	328	94.44	7	326	13	318	2.6e-40	135.1	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
2852595971	564	97.75	1	564	9	573	0.0e+00	735.3	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
2852595972	200	88.94	1	200	17	193	8.3e-43	143.1	COG3544	Uncharacterized conserved protein, DUF305 family	190
2852595973	96	97.75	4	94	2	88	1.3e-33	111.7	COG1937	DNA-binding transcriptional regulator, FrmR family	89
2852595974	97	97	1	96	3	99	1.6e-28	95.3	COG0011	Uncharacterized conserved protein YqgV, UPF0045/DUF77 family	100
2852595976	346	92.98	34	331	16	240	1.1e-39	133.3	COG1376	Lipoprotein-anchoring transpeptidase ErfK/SrfK	232
2852595977	658	99.54	1	657	4	656	0.0e+00	992.4	COG3590	Predicted metalloendopeptidase	654
2852595981	135	93.57	1	135	6	136	5.8e-41	135.7	COG1832	Predicted CoA-binding protein	140
2852595983	969	99.47	1	901	3	939	0.0e+00	677.5	COG2409	Uncharacterized membrane protein YdfJ, MMPL/SSD domain	937
2852595986	237	98.71	12	237	2	230	8.1e-84	277	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2852595987	445	84.01	13	442	56	386	9.2e-46	153.6	COG0642	Signal transduction histidine kinase	336
2852595988	126	28.53	3	125	175	285	4.2e-03	12.5	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
2852595989	378	94.14	16	353	14	318	1.1e-64	215.3	COG0392	Uncharacterized membrane protein YbhN, UPF0104 family	322
2852595990	387	97.5	15	369	7	357	1.6e-74	247.4	COG0628	Predicted PurR-regulated permease PerM	355
2852595991	997	81.53	1	764	3	770	0.0e+00	589.8	COG2409	Uncharacterized membrane protein YdfJ, MMPL/SSD domain	937
2852595993	246	98.68	20	246	2	225	2.4e-69	229.9	COG0220	tRNA G46 methylase TrmB	227
2852595996	608	99.51	1	606	3	607	0.0e+00	1031.1	COG1274	Phosphoenolpyruvate carboxykinase, GTP-dependent	608
2852595998	890	14.25	732	816	344	402	5.1e-78	3.7	COG3903	Predicted ATPase	414
2852595998	890	76.64	3	175	53	239	1.2e-30	103.5	COG2114	Adenylate cyclase, class 3	227
2852595998	890	97.34	194	604	3	405	5.1e-78	259.2	COG3903	Predicted ATPase	414
2852595999	503	95.42	2	503	17	558	1.0e-91	304.4	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2852596000	292	68.68	105	292	5	186	2.1e-42	141	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2852596001	237	96.65	1	233	8	238	2.9e-46	154.4	COG2188	DNA-binding transcriptional regulator, GntR family	236
2852596002	385	97.74	2	384	5	394	5.1e-125	414.1	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852596003	323	46.54	190	317	66	139	5.7e-32	23.7	COG2030	Acyl dehydratase	159
2852596003	323	90.57	1	152	13	156	5.7e-32	82.3	COG2030	Acyl dehydratase	159
2852596005	432	39.07	225	432	326	534	3.4e-46	105	COG1574	Predicted amidohydrolase YtcJ	535
2852596005	432	40.37	19	238	49	264	3.4e-46	52.9	COG1574	Predicted amidohydrolase YtcJ	535
2852596006	300	85.22	5	296	47	317	2.4e-63	211.1	COG0657	Acetyl esterase/lipase	312
2852596007	917	71.25	841	915	17	73	1.5e-14	48.5	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2852596008	720	90.98	4	336	13	375	9.3e-111	141.8	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852596008	720	92.48	350	717	29	397	9.3e-111	228.6	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852596009	407	85.85	49	399	38	310	1.2e-62	208.7	COG0657	Acetyl esterase/lipase	312
2852596011	410	87.74	76	409	35	313	2.7e-61	204.3	COG0657	Acetyl esterase/lipase	312
2852596012	544	97.36	33	544	6	558	6.7e-99	328.2	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2852596013	269	79.31	10	262	31	237	3.7e-28	94.9	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
2852596014	257	98.87	3	254	4	265	1.1e-74	247.4	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2852596017	190	87.5	3	190	24	205	6.5e-44	146.4	COG4339	Predicted metal-dependent phosphohydrolase, HD superfamily	208
2852596018	281	93.84	6	279	3	261	3.5e-86	285.8	COG2162	Arylamine N-acetyltransferase	275
2852596020	378	95.74	4	377	9	390	1.1e-62	205.3	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852596021	303	63.64	2	171	38	121	8.0e-16	54.1	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2852596022	173	84.71	2	168	3	146	1.9e-22	76.3	COG0262	Dihydrofolate reductase	167
2852596023	190	78.95	1	178	19	183	6.7e-15	52.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852596026	611	97.49	11	468	7	395	1.9e-79	264.3	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852596027	493	98.75	14	489	2	474	0.0e+00	550.4	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2852596028	254	69.89	4	249	38	232	2.8e-15	53.5	COG0500	SAM-dependent methyltransferase	257
2852596029	385	97.56	8	379	8	406	1.3e-34	117	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2852596032	389	92.54	2	385	9	368	4.1e-66	219.8	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
2852596033	489	96.48	1	488	13	560	5.0e-73	236.7	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2852596034	324	98.74	1	322	4	316	1.8e-115	382.1	COG1735	Predicted metal-dependent hydrolase, phosphotriesterase family	316
2852596035	548	96.94	1	546	2	539	0.0e+00	544.3	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
2852596038	313	58.24	102	305	58	209	2.4e-05	19.7	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
2852596039	275	84.95	2	274	13	283	1.4e-49	165.9	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
2852596040	355	74.82	28	352	1	312	1.0e-70	235.5	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
2852596041	207	94.74	1	198	8	205	2.0e-27	93.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852596042	601	96.28	2	592	20	589	2.1e-116	386.2	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2852596043	303	97.15	3	303	2	308	5.3e-60	199.6	COG0524	Sugar or nucleoside kinase, ribokinase family	311
2852596044	721	5.71	173	293	105	127	3.9e-21	6.6	COG3391	DNA-binding beta-propeller fold protein YncE	381
2852596044	721	19.85	611	720	79	158	3.9e-21	13.6	COG3391	DNA-binding beta-propeller fold protein YncE	381
2852596044	721	48.14	408	651	38	231	3.9e-21	53.4	COG3391	DNA-binding beta-propeller fold protein YncE	381
2852596046	199	82.03	1	192	39	216	4.5e-37	124.4	COG3786	L,D-peptidoglycan transpeptidase YkuD, ErfK/YbiS/YcfS/YnhG family	217
2852596047	282	22.01	67	153	92	126	3.8e-21	5.5	COG2030	Acyl dehydratase	159
2852596047	282	62.26	148	268	19	117	3.8e-21	65.5	COG2030	Acyl dehydratase	159
2852596048	449	32.84	48	202	125	212	9.2e-64	16.8	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852596048	449	98.13	204	445	3	265	9.2e-64	195	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852596049	432	99.49	6	432	2	393	1.7e-98	326.7	COG0183	Acetyl-CoA acetyltransferase	392
2852596051	309	89.8	6	308	18	325	4.8e-46	153.8	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852596053	424	89.87	10	420	38	374	8.4e-41	136.5	COG4585	Signal transduction histidine kinase	365
2852596054	215	91.94	2	214	2	195	3.2e-39	131.1	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2852596057	555	7.77	143	184	216	239	1.1e-19	9.2	COG3386	Sugar lactone lactonase YvrE	307
2852596057	555	17.8	182	252	31	85	1.1e-19	6	COG3386	Sugar lactone lactonase YvrE	307
2852596057	555	24.92	36	147	68	144	1.1e-19	11.7	COG3386	Sugar lactone lactonase YvrE	307
2852596057	555	31.39	443	555	36	132	1.1e-19	17	COG3386	Sugar lactone lactonase YvrE	307
2852596057	555	63.75	273	461	33	229	1.1e-19	26.4	COG3386	Sugar lactone lactonase YvrE	307
2852596059	611	97.24	12	467	7	394	8.4e-83	275.3	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852596060	349	86.57	1	330	14	316	6.4e-57	189.5	COG3804	Uncharacterized protein	350
2852596061	3654	59.26	3571	3642	30	77	5.8e-12	14	COG0236	Acyl carrier protein	80
2852596061	3654	82.72	1470	1543	10	76	5.8e-12	25.4	COG0236	Acyl carrier protein	80
2852596061	3654	90.99	7	1404	5	1084	0.0e+00	1134.4	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
2852596061	3654	94.52	1560	3005	3	1124	0.0e+00	1191.3	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
2852596063	993	98.51	1	993	5	932	0.0e+00	887.8	COG2409	Uncharacterized membrane protein YdfJ, MMPL/SSD domain	937
2852596064	584	97.54	2	584	10	563	5.6e-112	371.4	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2852596066	214	48.15	3	96	44	95	2.1e-04	18.1	COG3838	Type IV secretory pathway, VirB2 components (pilins)	108
2852596067	161	85.95	1	161	10	168	4.0e-36	121	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
2852596069	250	98.3	1	238	3	233	5.6e-64	211.9	COG0479	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit	234
2852596070	637	97.7	2	605	3	555	0.0e+00	698.5	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
2852596073	252	85.91	1	252	5	254	8.2e-59	195.7	COG2513	2-Methylisocitrate lyase and related enzymes, PEP mutase family	289
2852596074	122	28.87	12	120	109	192	1.6e-03	14.3	COG1426	Cytoskeletal protein RodZ, contains Xre-like HTH and DUF4115 domains	284
2852596075	853	99.5	2	823	4	800	0.0e+00	1006.6	COG1251	NAD(P)H-nitrite reductase, large subunit	793
2852596076	114	96.26	6	114	3	105	1.1e-19	66.8	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
2852596077	116	87.67	1	65	9	72	2.8e-13	46.1	COG1146	NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit	68
2852596078	253	85.79	2	178	26	182	3.1e-26	89.1	COG2032	Cu/Zn superoxide dismutase	179
2852596079	226	96.41	1	226	5	246	1.9e-43	145.4	COG2138	Sirohydrochlorin ferrochelatase	245
2852596080	382	98.4	11	278	2	247	6.2e-48	159.2	COG1587	Uroporphyrinogen-III synthase	248
2852596081	464	97.62	13	459	3	412	2.4e-129	428.3	COG2223	Nitrate/nitrite transporter NarK	417
2852596082	258	48.39	6	255	46	180	7.6e-15	52.1	COG0500	SAM-dependent methyltransferase	257
2852596083	194	52.47	6	156	34	118	1.2e-07	28.8	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2852596084	294	92.09	5	293	1	291	8.9e-98	323.6	COG1984	Allophanate hydrolase subunit 2	314
2852596085	226	85.46	16	226	18	211	2.2e-62	206.7	COG2049	Allophanate hydrolase subunit 1	223
2852596086	230	91.59	10	228	14	220	1.4e-46	155.1	COG1738	Uncharacterized PurR-regulated membrane protein YhhQ, DUF165 family	233
2852596087	314	95.06	6	314	12	319	1.2e-39	133	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
2852596088	1392	64.67	1001	1263	109	346	1.5e-31	105.7	COG2208	Serine phosphatase RsbU, regulator of sigma subunit	367
2852596088	1392	66.34	635	776	7	140	8.3e-20	67	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
2852596088	1392	73.6	245	577	101	390	6.7e-66	220.1	COG0642	Signal transduction histidine kinase	336
2852596089	101	56.41	1	98	12	77	4.1e-08	29.5	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
2852596090	85	22.08	1	85	213	299	3.0e-25	85.3	COG0050	Translation elongation factor EF-Tu, a GTPase	394
2852596091	457	71.19	11	425	27	367	7.2e-13	43.9	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2852596092	363	28.54	34	320	42	166	4.9e-04	13	COG1541	Phenylacetate-coenzyme A ligase PaaK, adenylate-forming domain family	438
2852596093	266	89.93	1	256	4	244	1.4e-43	145.9	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852596095	439	85.79	4	438	39	352	4.1e-31	102.8	COG2837	Periplasmic deferrochelatase/peroxidase EfeB	352
2852596101	200	81.82	9	196	12	182	4.5e-19	66.3	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852596102	199	98.02	1	199	3	200	6.3e-72	238	COG1279	Arginine exporter protein ArgO	202
2852596103	292	97.34	3	291	4	296	4.1e-36	121.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
2852596104	299	35.38	28	125	14	59	1.3e-05	21.3	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2852596105	340	98.87	1	340	4	352	4.5e-82	272.1	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
2852596106	722	98.79	7	722	5	740	0.0e+00	587.2	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
2852596107	325	98.6	1	324	1	282	3.8e-86	285.8	COG1319	CO or xanthine dehydrogenase, FAD-binding subunit	284
2852596108	207	96.79	53	206	3	153	6.3e-66	217.2	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
2852596110	168	18.12	1	54	7	31	8.5e-04	4.5	COG3439	Uncharacterized conserved protein, DUF302 family	137
2852596110	168	46.38	54	166	64	127	8.5e-04	9.6	COG3439	Uncharacterized conserved protein, DUF302 family	137
2852596112	506	98.38	1	365	1	364	1.3e-66	221.6	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852596113	390	85.95	2	379	19	336	2.7e-52	174.4	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852596114	434	96.22	1	366	10	365	2.1e-71	237.4	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852596115	360	92.7	3	356	8	350	7.0e-62	206	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852596116	341	85.14	2	337	9	323	6.8e-62	206	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852596117	406	81.08	11	349	9	308	4.1e-60	200	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852596118	546	96.83	11	546	8	557	1.9e-109	363.5	COG2303	Choline dehydrogenase or related flavoprotein	542
2852596120	161	75.19	22	144	28	127	1.1e-12	44.6	COG1846	DNA-binding transcriptional regulator, MarR family	126
2852596121	454	96.24	2	453	12	472	0.0e+00	469.2	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2852596122	208	78.47	1	205	3	166	7.6e-12	42.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852596123	311	64.64	2	210	15	195	9.7e-27	90	COG3687	Predicted metal-dependent hydrolase	280
2852596125	476	89.32	125	476	33	358	3.3e-91	302.8	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2852596126	118	48.09	6	103	38	100	2.9e-07	26.2	COG1917	Cupin domain protein related to quercetin dioxygenase	131
2852596136	163	68.39	19	156	32	137	7.7e-24	80.6	COG1403	5-methylcytosine-specific restriction endonuclease McrA	146
2852596149	451	48.56	246	444	5	190	4.1e-37	34.6	COG0477	MFS family permease	338
2852596149	451	69.19	23	299	4	268	4.1e-37	99.9	COG0477	MFS family permease	338
2852596151	869	81.25	788	866	12	76	1.8e-21	71	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2852596152	458	48.83	259	453	3	189	2.2e-34	22.9	COG0477	MFS family permease	338
2852596152	458	55.87	19	248	2	215	2.2e-34	98.4	COG0477	MFS family permease	338
2852596153	321	95.7	2	295	5	293	2.4e-74	246.5	COG3285	Eukaryotic-type DNA primase	299
2852596154	180	68.66	1	68	9	54	3.2e-09	33.4	COG3237	Uncharacterized conserved protein YjbJ, UPF0337 family	67
2852596157	470	98.42	1	464	5	440	1.7e-119	396.4	COG2252	Xanthine/uracil/vitamin C permease, AzgA family	436
2852596160	352	95.49	6	352	5	343	5.8e-68	225.6	COG1363	Putative aminopeptidase FrvX	355
2852596161	403	98.5	3	402	3	395	1.8e-104	346.4	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852596164	137	62.39	10	96	14	86	1.5e-04	17.6	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
2852596165	411	98.34	6	331	2	298	1.0e-111	369.3	COG3285	Eukaryotic-type DNA primase	299
2852596166	586	95.25	53	567	20	560	1.0e-95	317.5	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2852596169	338	97.54	44	328	2	279	2.3e-52	174.9	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
2852596170	498	90.65	28	498	20	465	5.4e-47	156.9	COG0531	Amino acid transporter	466
2852596171	360	97.67	56	349	2	295	1.1e-51	172.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
2852596172	331	98.86	1	331	2	347	0.0e+00	455	COG1088	dTDP-D-glucose 4,6-dehydratase	340
2852596173	293	80.83	1	264	38	290	1.7e-24	82.7	COG1216	Glycosyltransferase, GT2 family	305
2852596176	476	91.59	1	225	6	212	2.1e-22	75.4	COG3944	Capsular polysaccharide biosynthesis protein	226
2852596178	364	61.37	8	354	152	402	9.0e-16	55.2	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2852596179	917	91.91	6	493	4	446	5.5e-23	77.5	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
2852596179	917	98.78	527	892	3	406	1.7e-26	89.3	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2852596183	264	66.14	1	262	2	251	2.9e-68	226.9	COG1208	NDP-sugar pyrophosphorylase, includes eIF-2Bgamma, eIF-2Bepsilon, and LPS biosynthesis proteins	358
2852596184	393	98.67	14	389	4	373	1.1e-113	376.7	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
2852596185	343	98.13	1	308	2	316	3.4e-49	164.5	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2852596186	295	98.63	1	287	1	287	5.4e-109	360.1	COG1209	dTDP-glucose pyrophosphorylase	286
2852596187	135	64.41	18	118	14	89	7.8e-11	38.8	COG0640	DNA-binding transcriptional regulator, ArsR family	110
2852596188	504	86.22	289	504	32	225	7.1e-75	247.1	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
2852596189	199	97.74	13	193	5	177	1.5e-57	190.3	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase or related enzyme	173
2852596190	222	80.38	3	214	15	182	4.9e-12	43.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852596191	220	93.3	1	213	4	198	3.3e-26	89.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852596192	133	48.35	2	129	121	237	3.1e-09	33.4	COG2202	PAS domain	232
2852596193	1318	26.4	279	506	216	390	4.3e-120	118.3	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2852596193	1318	66.82	782	1316	202	644	4.3e-120	281.8	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2852596194	734	88.97	361	734	43	397	1.3e-113	230.1	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852596194	734	91.48	1	357	6	370	1.3e-113	151.6	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852596195	319	87.12	10	319	33	316	9.9e-85	280.7	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
2852596197	211	85.65	4	200	9	187	4.5e-22	76.2	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852596198	193	99.32	14	165	2	146	1.0e-24	84.8	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2852596201	205	90.91	2	201	10	199	1.1e-12	45.5	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852596202	299	88	3	299	37	300	2.3e-93	309.3	COG3662	Uncharacterized conserved protein, DUF2236 family	300
2852596203	196	42.62	7	148	62	165	1.2e-20	70.1	COG2227	2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase	243
2852596204	297	96	1	295	2	289	2.7e-89	295.7	COG3315	O-Methyltransferase involved in polyketide biosynthesis	297
2852596206	607	55.16	41	436	101	303	2.4e-05	20.8	COG0457	Tetratricopeptide (TPR) repeat	291
2852596208	1291	98.61	78	1269	6	924	0.0e+00	542.2	COG1674	DNA segregation ATPase FtsK/SpoIIIE and related proteins	858
2852596209	102	10.31	2	98	15	96	4.5e-01	5.6	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2852596210	512	99.44	4	505	2	530	1.4e-69	231.2	COG5651	PPE-repeat protein	490
2852596211	97	94.85	1	96	3	94	2.3e-04	17.9	COG4842	Uncharacterized conserved protein YukE	97
2852596212	95	96.91	1	95	2	95	8.8e-28	92.9	COG4842	Uncharacterized conserved protein YukE	97
2852596215	443	91.36	4	441	21	538	1.1e-41	139.9	COG1404	Serine protease, subtilisin family	508
2852596217	402	17.97	282	401	235	287	1.5e-08	13.7	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852596217	402	41.36	152	338	13	134	1.5e-08	25	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852596218	622	92.87	21	582	9	516	1.9e-60	201.5	COG1807	4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family	535
2852596219	256	98.83	1	254	2	255	5.0e-100	330.9	COG4106	Trans-aconitate methyltransferase	257
2852596220	266	98.4	1	266	5	250	5.0e-97	321.1	COG4424	LPS sulfotransferase NodH	250
2852596221	456	26.02	2	166	4	130	1.7e-72	120.4	COG3119	Arylsulfatase A or related enzyme	475
2852596221	456	44.47	123	410	247	463	1.7e-72	123.3	COG3119	Arylsulfatase A or related enzyme	475
2852596224	223	65.52	4	219	65	216	2.6e-19	65.9	COG0671	Membrane-associated phospholipid phosphatase	232
2852596225	497	68.1	25	195	57	214	5.7e-20	68.3	COG0671	Membrane-associated phospholipid phosphatase	232
2852596225	497	96.69	213	496	5	296	4.9e-42	140	COG1597	Diacylglycerol kinase family enzyme	301
2852596226	217	96.31	2	217	9	217	1.4e-61	204.3	COG3786	L,D-peptidoglycan transpeptidase YkuD, ErfK/YbiS/YcfS/YnhG family	217
2852596227	152	18.29	2	126	8	37	2.5e-02	7.8	COG5517	3-phenylpropionate/cinnamic acid dioxygenase, small subunit	164
2852596228	501	97.16	22	397	3	379	5.3e-43	144	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2852596229	588	29.91	73	346	228	329	3.1e-04	15.5	COG1077	Actin-like ATPase involved in cell morphogenesis	342
2852596230	333	96.56	3	317	3	311	6.0e-124	409.9	COG4608	ABC-type oligopeptide transport system, ATPase component	309
2852596231	334	99.38	5	322	1	323	0.0e+00	437.9	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
2852596232	320	99.69	1	316	1	317	5.9e-100	331.3	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2852596233	345	96.64	21	342	9	296	3.6e-89	295.1	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2852596234	550	92.51	1	547	5	535	8.7e-60	199.3	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
2852596237	548	27.14	109	539	207	529	3.4e-40	134.1	COG4934	Serine protease, subtilase family	1174
2852596238	611	13.33	2	46	71	88	1.0e-03	4.4	COG3791	Uncharacterized conserved protein	133
2852596238	611	28.89	320	404	68	106	1.0e-03	8.8	COG3791	Uncharacterized conserved protein	133
2852596241	489	79.2	20	469	66	503	9.5e-58	192.6	COG5305	Uncharacterized membrane protein	552
2852596242	392	90.84	3	382	3	359	2.3e-55	185	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2852596244	193	23.01	9	145	104	158	1.3e-13	47.2	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
2852596246	834	60.24	11	386	161	407	3.1e-40	44.5	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
2852596246	834	72.44	476	834	111	407	3.1e-40	90.1	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
2852596247	243	96.46	13	240	2	219	3.6e-78	258.3	COG1136	ABC-type lipoprotein export system, ATPase component	226
2852596250	307	41.74	65	279	155	303	3.8e-19	65.6	COG4124	Beta-mannanase	355
2852596251	256	97.76	3	253	5	266	5.8e-49	163.5	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852596252	121	84	1	91	8	91	2.8e-23	78.6	COG1188	Ribosomal 50S subunit-recycling heat shock protein, contains S4 domain	100
2852596255	356	97.63	36	327	5	292	2.5e-35	119	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852596259	329	98.69	5	315	4	305	3.4e-85	282.5	COG1131	ABC-type multidrug transport system, ATPase component	293
2852596261	319	59.73	80	309	88	262	3.5e-10	35.9	COG0842	ABC-type multidrug transport system, permease component	286
2852596262	429	96.44	1	408	12	417	3.1e-91	302.8	COG2124	Cytochrome P450	411
2852596264	124	67.81	7	122	2	100	3.2e-05	20.9	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2852596266	407	77.67	49	405	66	312	1.7e-18	63.5	COG0657	Acetyl esterase/lipase	312
2852596268	264	95.85	1	263	2	255	1.3e-74	247.2	COG0300	Short-chain dehydrogenase	265
2852596269	306	72.57	8	198	3	174	1.2e-20	66.1	COG0412	Dienelactone hydrolase	236
2852596270	186	66.99	1	182	3	142	3.4e-22	76.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852596272	190	98.92	1	184	2	184	1.4e-62	207.2	COG0717	Deoxycytidine triphosphate deaminase	183
2852596273	437	98.79	4	411	2	408	0.0e+00	487.8	COG0004	Ammonia channel protein AmtB	409
2852596274	518	12.95	203	508	242	277	3.0e-04	16.1	COG1512	Uncharacterized membrane protein YgcG, contains a TPM-fold domain	271
2852596275	449	99.76	1	424	1	417	0.0e+00	483.8	COG1004	UDP-glucose 6-dehydrogenase	414
2852596276	205	94.26	1	202	2	198	6.4e-23	79.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852596277	439	94.77	12	432	21	419	4.8e-103	341.7	COG2124	Cytochrome P450	411
2852596280	287	98.97	1	287	1	288	2.8e-117	387.4	COG1209	dTDP-glucose pyrophosphorylase	286
2852596281	549	40.69	395	549	87	250	2.6e-70	115.3	COG3391	DNA-binding beta-propeller fold protein YncE	381
2852596281	549	43.18	241	413	67	240	2.6e-70	133.3	COG3391	DNA-binding beta-propeller fold protein YncE	381
2852596282	412	76.62	54	407	80	374	1.3e-73	244.3	COG5438	Uncharacterized membrane protein	385
2852596284	424	99.75	27	423	2	396	9.3e-117	386.8	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
2852596285	985	98.5	288	737	6	400	1.1e-117	389.7	COG0247	Fe-S oxidoreductase	388
2852596287	843	75	772	841	18	77	1.5e-16	55	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2852596291	619	94.93	1	588	28	626	2.8e-30	101.6	COG0699	Replication fork clamp-binding protein CrfC (dynamin-like GTPase family)	546
2852596292	494	75.75	28	428	75	552	4.4e-13	45.2	COG0699	Replication fork clamp-binding protein CrfC (dynamin-like GTPase family)	546
2852596295	310	94.17	6	310	13	335	4.8e-60	199.7	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852596296	167	100	1	156	1	158	4.4e-64	211.2	COG2077	Peroxiredoxin	158
2852596299	238	49.49	3	228	32	224	8.6e-20	67.2	COG0426	Flavorubredoxin	388
2852596300	1063	76.23	18	228	46	231	8.3e-40	131.4	COG2114	Adenylate cyclase, class 3	227
2852596300	1063	80.98	559	1053	49	346	7.0e-05	19.1	COG0457	Tetratricopeptide (TPR) repeat	291
2852596301	410	97.55	1	406	2	399	1.4e-51	171.9	COG1819	UDP:flavonoid glycosyltransferase YjiC, YdhE family	406
2852596303	505	98.27	12	477	5	458	0.0e+00	562.7	COG1113	L-asparagine transporter and related permeases	462
2852596305	621	99.01	1	584	6	605	0.0e+00	822.9	COG0443	Molecular chaperone DnaK (HSP70)	579
2852596306	207	73.47	3	181	51	194	6.4e-38	127.1	COG0576	Molecular chaperone GrpE (heat shock protein)	193
2852596307	388	93.51	6	383	2	361	3.4e-124	411.2	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
2852596308	127	75.76	12	119	2	101	3.4e-24	82	COG0789	DNA-binding transcriptional regulator, MerR family	124
2852596309	300	88.18	2	300	26	301	2.8e-26	89	COG2017	Galactose mutarotase or related enzyme	308
2852596310	388	84.44	137	385	10	226	3.5e-58	192.9	COG0543	NAD(P)H-flavin reductase	252
2852596312	210	68.42	5	209	6	148	5.8e-16	56	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852596313	215	82.21	2	212	36	206	2.2e-08	29.8	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2852596315	856	98.51	5	854	3	795	0.0e+00	1102.7	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
2852596317	258	95.09	1	256	6	257	4.1e-70	232.4	COG0300	Short-chain dehydrogenase	265
2852596319	213	71.86	28	209	73	261	1.4e-35	119.2	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
2852596320	368	98.41	7	368	1	371	0.0e+00	534.1	COG4833	Predicted alpha-1,6-mannanase, GH76 family	377
2852596321	612	17.33	457	504	6	44	4.2e-09	3	COG2761	Predicted dithiol-disulfide isomerase, DsbA family	225
2852596321	612	42.67	498	610	98	193	4.2e-09	28.1	COG2761	Predicted dithiol-disulfide isomerase, DsbA family	225
2852596321	612	94.91	25	434	14	386	6.5e-99	327.6	COG3004	Na+/H+ antiporter NhaA	390
2852596322	233	93.27	13	227	13	206	2.8e-47	157.2	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
2852596323	337	99.12	1	337	2	339	2.3e-105	348.8	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
2852596324	912	82.85	450	912	89	513	4.6e-69	230.6	COG3227	Zn-dependent metalloprotease	507
2852596325	345	97.92	3	341	6	287	6.7e-92	304.2	COG0191	Fructose/tagatose bisphosphate aldolase	286
2852596329	297	96.32	1	287	10	297	5.8e-88	291.7	COG1230	Co/Zn/Cd efflux system component	296
2852596330	259	87.71	35	242	12	218	4.3e-28	95.3	COG1994	Zn-dependent protease (includes SpoIVFB)	230
2852596332	431	99.53	1	429	1	428	0.0e+00	615.9	COG0104	Adenylosuccinate synthase	430
2852596333	212	79.43	51	209	26	137	2.5e-11	39.7	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
2852596335	63	97.06	1	63	2	67	2.8e-17	59.4	COG1141	Ferredoxin	68
2852596336	401	95.72	1	401	17	419	1.5e-98	327	COG2124	Cytochrome P450	411
2852596337	268	96.27	3	268	10	293	2.2e-33	112.7	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852596338	679	21.44	437	677	728	929	2.2e-101	152.4	COG2409	Uncharacterized membrane protein YdfJ, MMPL/SSD domain	937
2852596338	679	49.26	1	451	10	473	2.2e-101	183.6	COG2409	Uncharacterized membrane protein YdfJ, MMPL/SSD domain	937
2852596339	160	78.95	18	155	26	130	4.0e-13	46	COG1846	DNA-binding transcriptional regulator, MarR family	126
2852596340	529	96.33	1	441	11	430	4.2e-90	298.6	COG0025	NhaP-type Na+/H+ or K+/H+ antiporter	429
2852596342	417	97.46	18	415	6	389	0.0e+00	490.4	COG0027	Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase)	394
2852596344	137	92.98	3	137	6	111	6.2e-18	60.8	COG0607	Rhodanese-related sulfurtransferase	110
2852596345	406	94.46	15	406	20	394	0.0e+00	444.9	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
2852596348	287	90.3	2	254	2	243	4.3e-55	183.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852596350	163	83.95	5	150	19	154	1.9e-10	37.8	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2852596351	355	19.24	240	330	278	343	6.2e-40	19	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852596351	355	56.85	12	261	9	203	6.2e-40	117.3	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852596352	371	29.15	12	128	9	108	2.9e-46	90.5	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852596352	371	60.35	156	370	132	338	2.9e-46	68	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852596353	444	95.34	17	431	17	343	2.0e-81	269.9	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852596355	608	61.65	113	555	78	384	5.1e-20	68.3	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
2852596356	920	20.49	209	362	14	55	4.2e-15	9.4	COG2078	Uncharacterized conserved protein, AMMECR1 domain	203
2852596356	920	62.93	412	574	44	172	4.2e-15	40	COG2078	Uncharacterized conserved protein, AMMECR1 domain	203
2852596356	920	85.22	4	197	3	175	1.4e-17	60	COG0461	Orotate phosphoribosyltransferase	201
2852596358	246	78.08	1	246	21	223	3.8e-33	111.6	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2852596359	336	96.79	1	334	4	335	1.2e-69	231.5	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852596360	687	99.39	365	687	1	325	0.0e+00	441.2	COG0280	Phosphotransacetylase	327
2852596361	376	99.25	3	376	2	396	0.0e+00	458.2	COG0282	Acetate kinase	396
2852596362	90	72.65	1	89	17	101	3.9e-10	36	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
2852596363	760	66.17	129	490	3	313	6.0e-39	130.7	COG0515	Serine/threonine protein kinase	384
2852596364	317	90.11	1	313	25	279	9.2e-59	195.6	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2852596366	167	78.49	10	158	14	148	5.2e-21	71.7	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2852596367	223	96.21	6	222	5	207	3.9e-67	221.8	COG0352	Thiamine monophosphate synthase	211
2852596368	455	28.5	269	420	266	377	3.8e-19	30	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2852596368	455	40.97	6	191	5	165	3.8e-19	38.5	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2852596370	337	92.01	2	330	7	363	2.7e-48	161.1	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2852596371	65	97.06	1	65	3	68	1.9e-22	75.8	COG2104	Sulfur carrier protein ThiS (thiamine biosynthesis)	68
2852596372	252	95.42	1	252	5	254	1.6e-114	378.1	COG2022	Thiamin biosynthesis thiazole synthase ThiGH, ThiG subunit	262
2852596373	252	90.05	1	251	12	210	1.8e-09	34.2	COG2755	Lysophospholipase L1 or related esterase	216
2852596374	305	99.02	1	296	3	305	3.6e-72	239.9	COG1131	ABC-type multidrug transport system, ATPase component	293
2852596376	228	66.11	3	224	32	230	7.8e-18	61.4	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
2852596377	502	99.32	45	499	1	438	1.2e-70	234.9	COG2234	Zn-dependent amino- or carboxypeptidase, M28 family	435
2852596379	390	93.88	23	381	3	355	9.0e-52	172.8	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
2852596380	103	39.78	9	98	89	162	2.9e-06	23.5	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2852596381	291	93.63	9	282	11	260	5.9e-59	195.9	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
2852596382	313	94.79	12	313	11	283	1.8e-68	227.4	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
2852596383	409	83.07	7	407	31	344	2.8e-52	174.3	COG0687	Spermidine/putrescine-binding periplasmic protein	363
2852596384	461	98.38	29	460	4	428	2.1e-128	424.9	COG0001	Glutamate-1-semialdehyde aminotransferase	432
2852596385	381	97.45	2	362	5	348	5.8e-128	423.5	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2852596386	215	89.47	1	202	8	194	9.7e-17	58.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852596387	538	98.79	2	538	3	493	8.4e-102	338.2	COG1233	Phytoene dehydrogenase-related protein	487
2852596388	688	8.99	621	687	190	246	2.8e-76	5.2	COG1042	Acyl-CoA synthetase (NDP forming)	598
2852596388	688	98.11	23	612	10	631	2.8e-76	252.7	COG1042	Acyl-CoA synthetase (NDP forming)	598
2852596389	427	99	3	381	3	397	3.9e-83	276.2	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852596390	365	26.13	267	357	221	301	8.8e-47	33.6	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
2852596390	365	59.35	78	273	6	189	8.8e-47	127.6	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
2852596391	407	63.47	4	354	58	335	9.6e-34	113.1	COG2115	Xylose isomerase	438
2852596393	408	98.45	3	382	3	384	1.2e-64	215.5	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2852596394	387	97.99	1	381	4	394	2.8e-84	280	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852596395	430	94.3	9	414	6	435	1.6e-98	326.4	COG2233	Xanthine/uracil permease	451
2852596396	141	61.83	43	135	50	130	1.8e-17	59.7	COG5485	Predicted ester cyclase	131
2852596397	216	78.47	3	208	11	174	5.5e-21	72.5	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852596398	510	42.71	182	443	8	133	7.3e-03	11	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852596399	414	89.02	2	413	8	445	1.4e-65	218.2	COG0531	Amino acid transporter	466
2852596402	412	90.43	203	409	12	200	1.8e-43	79.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852596402	412	91.87	1	211	11	202	1.8e-43	72	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852596403	88	49.62	3	84	12	76	6.9e-08	29.3	COG4270	Uncharacterized membrane protein	131
2852596404	494	95.29	1	447	6	430	1.8e-104	346.9	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
2852596407	177	16.71	7	166	104	167	1.1e-04	18.7	COG0477	MFS family permease	338
2852596408	205	92.96	5	205	4	201	3.8e-80	264.9	COG3571	Predicted hydrolase of the alpha/beta-hydrolase fold	213
2852596409	278	96.96	11	277	4	258	1.6e-93	309.2	COG0351	Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase	263
2852596410	519	99.08	70	500	3	432	0.0e+00	723.7	COG0422	Thiamine biosynthesis protein ThiC	432
2852596412	589	66.06	315	581	15	267	2.4e-34	25.4	COG0477	MFS family permease	338
2852596412	589	82.77	36	338	6	322	2.4e-34	92.2	COG0477	MFS family permease	338
2852596413	311	79.31	60	293	41	247	1.4e-22	76.3	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
2852596414	266	99.23	1	266	1	257	1.7e-77	256.7	COG0708	Exonuclease III	261
2852596415	291	42.33	146	290	87	166	7.1e-11	38.6	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2852596416	197	98.22	1	179	2	167	3.5e-50	166.3	COG0242	Peptide deformylase	168
2852596419	234	93.44	3	232	13	183	3.3e-44	147.4	COG2032	Cu/Zn superoxide dismutase	179
2852596420	379	97.83	18	379	2	362	0.0e+00	496.1	COG2170	Gamma-glutamyl:cysteine ligase YbdK, ATP-grasp superfamily	369
2852596421	210	94.12	1	210	12	219	2.8e-53	177.7	COG2802	Uncharacterized protein, similar to the N-terminal domain of Lon protease	221
2852596422	302	95.67	2	300	2	288	2.7e-77	256.3	COG3315	O-Methyltransferase involved in polyketide biosynthesis	297
2852596423	120	84.07	1	109	2	96	2.5e-23	78.8	COG1320	Multisubunit Na+/H+ antiporter, MnhG subunit	113
2852596424	95	88.76	1	84	5	83	2.8e-17	59.3	COG2212	Multisubunit Na+/H+ antiporter, MnhF subunit	89
2852596425	177	94.94	4	163	6	155	2.6e-26	89.1	COG1863	Multisubunit Na+/H+ antiporter, MnhE subunit	158
2852596426	532	99.01	3	532	4	504	2.0e-122	405.7	COG0651	Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit	504
2852596427	156	91.23	1	115	5	108	1.0e-29	99.1	COG1006	Multisubunit Na+/H+ antiporter, MnhC subunit	115
2852596428	934	79.58	4	593	53	543	0.0e+00	458.5	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
2852596429	156	73.47	1	83	15	86	1.3e-02	11.6	COG4829	Muconolactone delta-isomerase	98
2852596430	147	80.89	1	145	8	134	3.3e-09	33.1	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
2852596431	130	70	1	130	55	187	1.2e-28	96.8	COG2320	GrpB domain, predicted nucleotidyltransferase, UPF0157 family	185
2852596432	732	29.87	211	362	256	413	5.1e-129	51.6	COG0464	AAA+-type ATPase, SpoVK/Ycf46/Vps4 family	494
2852596432	732	84.5	293	731	80	526	5.1e-129	382.9	COG0464	AAA+-type ATPase, SpoVK/Ycf46/Vps4 family	494
2852596433	284	94.51	6	252	7	230	1.3e-63	211.3	COG1183	Phosphatidylserine synthase	234
2852596434	232	91.86	7	232	19	255	4.1e-48	159.9	COG0688	Phosphatidylserine decarboxylase	239
2852596435	397	97.79	1	397	6	403	0.0e+00	447.8	COG0303	Molybdopterin biosynthesis enzyme	404
2852596436	303	89.55	11	264	2	241	3.1e-46	154.6	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852596437	162	94.41	3	161	9	160	2.1e-43	144.5	COG3402	Uncharacterized membrane protein YdbS, contains bPH2 (bacterial pleckstrin homology) domain	161
2852596438	476	99.19	4	473	5	495	1.7e-107	356.7	COG3428	Uncharacterized membrane protein YdbT, contains bPH2 (bacterial pleckstrin homology) domain	494
2852596439	158	97.95	3	151	2	144	5.3e-08	29.9	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2852596440	271	94.81	1	271	10	265	7.3e-57	189.3	COG0647	Ribonucleotide monophosphatase NagD, HAD superfamily	269
2852596442	237	83.93	20	236	28	215	1.8e-22	76	COG3340	Peptidase E	224
2852596443	155	57.96	1	143	9	99	3.8e-03	13.4	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
2852596444	559	91.99	3	470	39	486	1.1e-86	288.1	COG1061	Superfamily II DNA or RNA helicase	442
2852596445	845	12.22	9	134	6	120	0.0e+00	137.4	COG0178	Excinuclease UvrABC ATPase subunit	935
2852596445	845	72.16	129	841	261	939	0.0e+00	813.3	COG0178	Excinuclease UvrABC ATPase subunit	935
2852596446	165	88.37	12	140	5	118	5.4e-15	51.4	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
2852596447	329	55.11	79	287	86	236	3.4e-09	32.1	COG1240	Mg-chelatase subunit ChlD	261
2852596448	330	55.84	37	251	84	236	7.2e-13	44.8	COG1240	Mg-chelatase subunit ChlD	261
2852596449	302	90.67	10	298	2	244	2.9e-50	167.8	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852596450	187	91.87	1	187	6	197	9.4e-21	72	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852596451	541	98.36	1	534	2	542	0.0e+00	595	COG0459	Chaperonin GroEL (HSP60 family)	524
2852596453	265	59.44	37	222	60	229	3.3e-16	55.5	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
2852596455	277	3.8	6	71	47	66	1.2e-03	3.9	COG3511	Phospholipase C	527
2852596455	277	13.28	138	272	285	354	1.2e-03	9	COG3511	Phospholipase C	527
2852596456	577	98.27	1	576	5	573	0.0e+00	457.8	COG3653	N-acyl-D-aspartate/D-glutamate deacylase	579
2852596457	129	97.26	1	121	3	144	8.5e-12	41.4	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2852596458	362	21	302	356	127	168	1.1e-03	6.3	COG2263	Predicted RNA methylase	198
2852596458	362	29.5	163	255	27	85	1.1e-03	6.3	COG2263	Predicted RNA methylase	198
2852596459	1106	79.92	7	199	48	242	7.6e-40	133.5	COG2114	Adenylate cyclase, class 3	227
2852596459	1106	87.5	1025	1103	8	77	5.3e-24	78.4	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2852596459	1106	98.31	218	629	2	408	0.0e+00	529.8	COG3903	Predicted ATPase	414
2852596461	164	64.22	22	160	62	210	9.7e-05	18.2	COG0671	Membrane-associated phospholipid phosphatase	232
2852596462	505	95.82	3	470	16	474	0.0e+00	456.4	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2852596463	284	92.96	3	266	19	269	3.8e-115	380.4	COG2326	Polyphosphate kinase 2, PPK2 family	270
2852596466	302	96.98	5	275	4	260	2.8e-56	187.2	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2852596467	667	99.56	2	666	3	675	0.0e+00	834.9	COG1505	Prolyl oligopeptidase PreP, S9A serine peptidase family	648
2852596468	211	98.63	1	148	1	144	5.7e-29	97.2	COG3427	Carbon monoxide dehydrogenase subunit G	146
2852596469	284	97.9	3	284	3	282	1.3e-82	274.2	COG1319	CO or xanthine dehydrogenase, FAD-binding subunit	284
2852596470	797	99.33	4	784	5	744	0.0e+00	705.1	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
2852596471	168	98.08	1	155	2	154	1.5e-61	203.1	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
2852596472	363	94.96	2	363	16	392	2.1e-76	251.7	COG3552	Uncharacterized conserved protein, contains von Willebrand factor type A (vWA) domain	395
2852596473	295	83.64	3	294	13	288	1.4e-65	218	COG0714	MoxR-like ATPase	329
2852596476	464	99.12	1	454	4	454	0.0e+00	540	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
2852596477	96	21.16	2	95	199	271	5.3e-04	15.9	COG1294	Cytochrome bd-type quinol oxidase, subunit 2	346
2852596478	136	17.26	78	129	62	95	5.2e-04	14.7	COG3374	Uncharacterized membrane protein	197
2852596478	136	34.01	5	86	93	159	5.2e-04	5.6	COG3374	Uncharacterized membrane protein	197
2852596481	180	97.85	7	177	4	185	3.6e-20	69.3	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
2852596482	475	63.85	5	130	2	84	6.4e-16	54.2	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2852596482	475	99.4	143	473	2	331	0.0e+00	494.3	COG3800	Predicted transcriptional regulator	332
2852596483	271	98	9	270	5	249	6.2e-102	336.6	COG3884	Acyl-ACP thioesterase	250
2852596484	428	38.98	245	427	289	472	0.0e+00	269.8	COG2224	Isocitrate lyase	433
2852596484	428	53.81	6	252	9	262	0.0e+00	350.1	COG2224	Isocitrate lyase	433
2852596485	286	85.71	3	286	2	283	3.7e-111	368	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
2852596487	290	84.07	12	272	40	266	9.2e-76	251.3	COG2326	Polyphosphate kinase 2, PPK2 family	270
2852596488	236	93.78	10	211	5	200	1.3e-18	64.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852596489	438	99.76	28	438	2	415	0.0e+00	525.5	COG2733	Uncharacterized membrane-anchored protein YjiN, DUF445 family	415
2852596490	152	54.62	21	146	2	72	1.8e-16	57.5	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2852596491	205	57.14	36	161	6	53	4.1e-03	11.9	COG1977	Molybdopterin converting factor, small subunit	84
2852596492	93	67.31	1	82	14	83	1.0e-02	12.7	COG4042	Energy-converting hydrogenase Eha subunit A	104
2852596494	227	96.05	3	227	3	221	2.8e-76	252.4	COG0274	Deoxyribose-phosphate aldolase	228
2852596496	274	96.4	1	271	3	270	3.0e-55	183.6	COG0388	Predicted amidohydrolase	274
2852596500	348	98.64	9	348	3	292	7.8e-88	290.6	COG0812	UDP-N-acetylenolpyruvoylglucosamine reductase	291
2852596501	429	97.11	107	373	6	240	1.7e-32	109.5	COG1376	Lipoprotein-anchoring transpeptidase ErfK/SrfK	232
2852596502	251	98.37	3	241	4	245	6.7e-78	258.1	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
2852596503	434	80.65	112	423	2	251	1.6e-35	118.9	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
2852596504	434	97.31	11	407	6	403	2.2e-47	158.8	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2852596506	248	96.96	3	232	3	225	6.1e-101	333.5	COG0588	Phosphoglycerate mutase (BPG-dependent)	230
2852596507	395	63.2	7	385	141	389	1.6e-66	221.8	COG0642	Signal transduction histidine kinase	336
2852596508	228	98.28	2	228	2	229	9.3e-87	286.7	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2852596511	321	62.22	1	321	4	311	5.4e-98	325.4	COG0248	Exopolyphosphatase/pppGpp-phosphohydrolase	492
2852596513	281	98.92	3	281	2	276	8.3e-38	126.5	COG1082	Sugar phosphate isomerase/epimerase	274
2852596515	290	99.63	1	288	1	267	6.5e-90	297.7	COG0345	Pyrroline-5-carboxylate reductase	266
2852596516	102	55.71	40	97	11	49	1.0e-04	18.4	COG3311	Predicted DNA-binding transcriptional regulator AlpA	70
2852596518	362	96.57	20	336	4	313	5.2e-39	131	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2852596519	356	90.04	82	338	12	246	8.1e-36	119.7	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
2852596520	179	84.91	3	149	22	156	8.6e-12	40.2	COG2030	Acyl dehydratase	159
2852596521	302	95.75	47	275	6	208	1.5e-59	197.2	COG0560	Phosphoserine phosphatase	212
2852596522	85	80	3	82	3	66	1.5e-03	15	COG0695	Glutaredoxin	80
2852596523	447	99.28	1	426	3	413	0.0e+00	449.2	COG0373	Glutamyl-tRNA reductase	414
2852596524	317	98.7	5	315	3	305	1.2e-99	329.8	COG0181	Porphobilinogen deaminase	307
2852596525	556	98.8	286	540	1	247	5.0e-78	257.1	COG1587	Uroporphyrinogen-III synthase	248
2852596525	556	99.59	11	280	2	244	9.0e-69	227.6	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
2852596526	292	88.18	1	292	37	327	1.1e-123	409	COG0113	Delta-aminolevulinic acid dehydratase, porphobilinogen synthase	330
2852596527	139	20.43	106	137	8	26	3.5e-02	2.8	COG1314	Preprotein translocase subunit SecG	86
2852596527	139	44.09	50	120	5	45	3.5e-02	8.3	COG1314	Preprotein translocase subunit SecG	86
2852596528	124	26.99	1	122	178	282	1.4e-02	10.9	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
2852596530	74	10.98	3	73	437	492	2.1e-02	10.8	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
2852596531	284	85.67	3	284	28	284	5.9e-68	225.9	COG3662	Uncharacterized conserved protein, DUF2236 family	300
2852596532	198	90.43	5	196	16	204	3.2e-19	66.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852596535	456	89.79	15	456	43	420	4.3e-76	252.9	COG2124	Cytochrome P450	411
2852596538	438	98.61	6	434	5	430	0.0e+00	586.2	COG0001	Glutamate-1-semialdehyde aminotransferase	432
2852596539	202	90.43	3	199	3	191	1.2e-30	102.8	COG0406	Broad specificity phosphatase PhoE	208
2852596540	198	80	24	195	25	144	6.2e-14	48.9	COG0526	Thiol-disulfide isomerase or thioredoxin	127
2852596541	256	96.48	6	233	8	226	4.6e-62	206	COG0785	Cytochrome c biogenesis protein CcdA	220
2852596542	523	97.31	20	523	1	507	0.0e+00	563.7	COG1333	Cytochrome c biogenesis protein ResB	478
2852596543	316	88.3	51	314	34	282	3.0e-72	240.1	COG0755	ABC-type transport system involved in cytochrome c biogenesis, permease component	281
2852596544	364	93.61	109	363	2	250	3.0e-52	174.1	COG0455	MinD-like ATPase involved in chromosome partitioning or flagellar assembly	262
2852596547	344	92.42	4	344	25	402	2.0e-28	92.5	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
2852596548	484	96.19	1	440	8	436	3.1e-107	356	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
2852596550	527	92	10	524	31	375	2.0e-45	151.2	COG4585	Signal transduction histidine kinase	365
2852596551	131	80.45	6	129	7	113	3.3e-17	59.1	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2852596552	217	97.16	4	217	2	206	2.5e-44	147.9	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2852596559	290	46.04	14	274	173	364	7.4e-31	104	COG1721	Uncharacterized conserved protein, DUF58 family, contains vWF domain	416
2852596560	330	95.15	5	330	16	329	6.5e-86	284.9	COG0714	MoxR-like ATPase	329
2852596561	66	17.81	17	63	6	44	5.7e-03	13.1	COG2345	Predicted transcriptional regulator, ArsR family	218
2852596562	188	15.9	4	186	2	129	5.0e-08	24.1	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
2852596563	289	96.7	1	289	7	299	3.3e-90	298.8	COG1575	1,4-dihydroxy-2-naphthoate octaprenyltransferase	303
2852596565	258	92.78	1	236	19	262	7.6e-76	251.7	COG0005	Purine nucleoside phosphorylase	262
2852596566	343	96.26	2	339	3	311	4.3e-78	259.4	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2852596568	372	91.01	1	370	29	342	5.1e-61	203.1	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
2852596571	339	78.17	3	339	81	388	1.1e-58	196.2	COG0642	Signal transduction histidine kinase	336
2852596572	227	98.28	2	225	2	229	9.5e-78	257.2	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2852596573	215	37.88	1	187	2	137	7.6e-20	69	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2852596574	223	98.58	1	213	4	211	3.8e-62	206.2	COG3222	Uncharacterized conserved protein, glycosyltransferase A (GT-A) superfamily, DUF2064 family	211
2852596575	209	57.35	2	203	16	175	8.2e-07	26.1	COG0500	SAM-dependent methyltransferase	257
2852596576	366	29.07	34	204	56	139	7.6e-29	10.3	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
2852596576	366	48.79	211	366	97	237	7.6e-29	85.1	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
2852596578	161	65.59	11	149	61	182	2.8e-27	92.4	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
2852596579	297	87.63	1	167	15	177	7.2e-33	110	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2852596581	160	86.81	6	153	15	172	3.0e-21	65	COG3059	Uncharacterized membrane protein YkgB	182
2852596582	273	80.25	128	269	24	153	3.0e-06	23.6	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2852596583	195	75.6	1	195	17	174	1.1e-17	62.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852596584	253	98.88	2	252	3	267	5.0e-65	216.2	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852596585	204	95.98	2	180	3	169	2.4e-29	99	COG3576	Predicted flavin-nucleotide-binding protein, pyridoxine 5'-phosphate oxidase superfamily	173
2852596586	832	99.07	12	824	6	750	0.0e+00	882.5	COG0058	Glucan phosphorylase	750
2852596588	358	66.73	7	358	179	557	1.1e-51	167.5	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2852596590	415	98.87	4	348	3	352	1.7e-87	289.8	COG0306	Phosphate/sulfate permease	326
2852596592	101	22.4	11	88	141	196	9.3e-03	11.8	COG3719	Ribonuclease I	249
2852596593	123	78.77	9	119	11	125	1.1e-07	29.2	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2852596594	515	97.18	1	514	9	560	3.9e-127	421.4	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2852596595	292	88.06	34	286	2	237	3.1e-52	174.2	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852596598	394	78.65	21	298	40	260	3.6e-20	67.8	COG2339	Membrane proteinase PrsW, cleaves anti-sigma factor RsiW, M82 family	274
2852596600	502	94.62	12	189	3	178	1.1e-29	99.7	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2852596602	303	99.29	4	303	2	281	0.0e+00	446	COG0447	1,4-Dihydroxy-2-naphthoyl-CoA synthase	282
2852596604	227	83.55	1	216	2	194	1.8e-31	106.2	COG1011	FMN phosphatase YigB, HAD superfamily	229
2852596605	413	97.83	3	412	5	410	0.0e+00	496.1	COG4941	Predicted RNA polymerase sigma factor, contains C-terminal TPR domain	415
2852596606	219	81.51	1	218	9	224	7.1e-38	127	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2852596607	206	88.52	1	198	15	199	7.6e-17	59.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852596610	536	93.66	14	535	29	560	3.0e-96	319.4	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2852596611	156	96.75	2	125	2	120	4.6e-29	97.2	COG3795	Uncharacterized conserved protein	123
2852596612	534	99.07	1	533	4	533	0.0e+00	462.8	COG1574	Predicted amidohydrolase YtcJ	535
2852596613	522	95.77	4	521	17	560	9.1e-116	383.7	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2852596614	320	15.28	8	83	17	73	9.1e-46	20.1	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
2852596614	320	56.3	71	320	157	366	9.1e-46	133.2	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
2852596615	381	86.88	9	378	28	325	1.1e-58	195.4	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852596616	330	96	6	330	8	319	3.3e-84	279.1	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
2852596617	240	56.62	1	224	9	192	1.1e-29	100	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
2852596618	293	84.5	160	291	17	125	8.2e-16	53.9	COG2852	Very-short-patch-repair endonuclease	129
2852596619	259	95.93	1	259	10	292	2.8e-41	138.6	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852596620	494	96.21	8	466	10	440	1.7e-100	333	COG1457	Purine-cytosine permease or related protein	442
2852596621	552	98.24	1	552	5	562	0.0e+00	576	COG1165	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase	566
2852596623	229	31.73	6	179	57	135	1.6e-09	33.6	COG1651	Protein-disulfide isomerase	244
2852596624	375	99.02	1	370	3	407	1.7e-39	133.2	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2852596625	274	92.16	1	247	3	249	3.6e-56	187.1	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852596626	230	97.91	1	228	6	239	7.7e-74	244.3	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
2852596627	528	98.79	1	522	1	491	9.8e-98	324.7	COG1233	Phytoene dehydrogenase-related protein	487
2852596628	199	88.52	3	198	9	193	2.9e-22	76.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852596630	143	16.26	66	134	229	275	8.8e-19	19.8	COG5483	Uncharacterized conserved protein, DUF488 family	289
2852596630	143	22.15	2	77	3	66	8.8e-19	43.6	COG5483	Uncharacterized conserved protein, DUF488 family	289
2852596633	329	97.29	37	329	5	291	6.0e-36	121.1	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852596634	300	75.79	3	299	58	298	1.0e-47	159.5	COG0657	Acetyl esterase/lipase	312
2852596635	406	97.54	2	398	2	398	5.2e-76	252.7	COG0644	Dehydrogenase (flavoprotein)	396
2852596636	335	99.39	16	335	2	327	3.7e-94	311.9	COG0142	Geranylgeranyl pyrophosphate synthase	322
2852596637	292	91.03	2	289	25	308	5.9e-75	248.9	COG0501	Zn-dependent protease with chaperone function	302
2852596640	341	98.78	7	335	3	327	3.3e-117	387.9	COG0240	Glycerol-3-phosphate dehydrogenase	329
2852596641	163	98.18	1	163	3	164	3.9e-68	225.3	COG1666	Uncharacterized conserved protein YajQ, UPF0234 family	165
2852596647	198	84.69	1	193	6	182	2.1e-20	70.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852596652	718	99.44	6	712	4	710	0.0e+00	668.6	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
2852596656	119	87.29	21	118	6	108	2.4e-16	56.6	COG0640	DNA-binding transcriptional regulator, ArsR family	110
2852596657	133	66.44	1	116	6	102	6.1e-06	21.8	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2852596658	255	20.82	180	245	66	116	1.1e-36	26.9	COG0580	Glycerol uptake facilitator and related aquaporins (Major Intrinsic Protein Family)	241
2852596658	255	97.14	9	231	6	243	1.1e-36	108.3	COG0580	Glycerol uptake facilitator and related aquaporins (Major Intrinsic Protein Family)	241
2852596659	132	97.97	2	131	3	147	1.4e-29	99.6	COG0394	Protein-tyrosine-phosphatase	139
2852596660	287	91.04	26	276	4	247	1.6e-51	171.9	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852596661	519	95.77	34	518	11	554	4.6e-84	278.8	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2852596662	319	95.33	7	314	12	297	9.2e-29	96.8	COG2040	Homocysteine/selenocysteine methylase (S-methylmethionine-dependent)	300
2852596665	480	33.54	70	149	23	76	2.2e+00	6.4	COG0711	FoF1-type ATP synthase, membrane subunit b or b'	161
2852596665	480	37.89	271	346	63	123	2.2e+00	4.1	COG0711	FoF1-type ATP synthase, membrane subunit b or b'	161
2852596667	446	98.57	5	436	6	420	6.0e-105	347.9	COG2124	Cytochrome P450	411
2852596668	337	81.08	1	318	4	333	2.2e-34	115.5	COG0644	Dehydrogenase (flavoprotein)	396
2852596669	167	96.51	1	167	3	168	3.1e-52	173.3	COG1755	Uncharacterized protein YpbQ, isoprenylcysteine carboxyl methyltransferase (ICMT) family	172
2852596670	353	99.16	1	353	1	353	0.0e+00	458.1	COG3424	Predicted naringenin-chalcone synthase	356
2852596671	738	78.34	1	715	23	760	0.0e+00	446.2	COG2409	Uncharacterized membrane protein YdfJ, MMPL/SSD domain	937
2852596672	523	68.09	7	419	3	322	1.0e-57	192.6	COG0515	Serine/threonine protein kinase	384
2852596673	317	82.52	14	315	46	314	1.3e-59	198	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
2852596674	441	98.66	4	411	4	371	5.2e-82	272.1	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
2852596675	267	98.78	13	257	2	244	2.0e-61	203.6	COG1414	DNA-binding transcriptional regulator, IclR family	246
2852596676	240	96.53	1	239	6	255	2.0e-17	59.8	COG0730	Uncharacterized membrane protein YfcA	258
2852596677	331	96.25	2	310	2	309	2.9e-111	368.2	COG4608	ABC-type oligopeptide transport system, ATPase component	309
2852596678	334	99.08	15	329	1	322	1.3e-122	405.2	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
2852596679	325	96.98	13	306	8	296	8.3e-81	267.6	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2852596680	308	99.06	1	305	1	315	1.9e-93	309.7	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2852596681	514	96.71	1	506	8	566	4.1e-74	246.9	COG0747	ABC-type transport system, periplasmic component	556
2852596682	320	98.47	1	311	4	325	2.3e-92	305.8	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
2852596683	439	22.9	244	408	249	338	3.0e-14	23.9	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2852596683	439	38.42	1	181	12	162	3.0e-14	27.7	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2852596685	312	97.67	2	301	2	295	4.6e-64	213.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2852596686	421	97.86	7	395	7	371	2.9e-71	236.6	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
2852596687	312	97.66	1	306	3	294	4.2e-66	219.2	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
2852596688	532	98.75	13	507	2	474	2.8e-70	233.4	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2852596689	416	98.79	9	416	3	411	1.3e-112	373.1	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
2852596690	294	96.15	3	293	12	286	2.6e-99	328.3	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
2852596691	308	96.5	14	307	11	286	1.3e-111	368.7	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
2852596692	265	84.31	5	250	8	238	2.0e-30	102.1	COG3570	Streptomycin 6-kinase	274
2852596693	714	80	217	501	43	278	3.3e-06	16.5	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852596694	152	57.8	21	151	6	131	9.8e-15	51	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2852596696	339	86.3	3	337	16	311	9.7e-52	172.4	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852596697	128	93.6	1	120	8	124	1.6e-56	186.3	COG3651	Uncharacterized conserved protein, DUF2237 family	125
2852596700	421	88.33	13	330	17	243	4.9e-39	130.1	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
2852596701	431	93.99	251	429	6	177	8.9e-45	148.6	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2852596702	598	65.74	7	339	3	311	5.7e-59	196.6	COG0515	Serine/threonine protein kinase	384
2852596705	67	98.51	1	67	1	66	2.6e-36	120	COG1278	Cold shock protein, CspA family	67
2852596711	454	97.36	1	450	8	449	1.7e-99	330.3	COG1231	Monoamine oxidase	450
2852596715	398	68.75	77	386	92	300	7.8e-14	48.1	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
2852596716	573	98.45	1	573	7	576	4.7e-108	358.7	COG3653	N-acyl-D-aspartate/D-glutamate deacylase	579
2852596717	400	87.89	15	399	50	419	4.5e-94	312.2	COG2124	Cytochrome P450	411
2852596718	881	75.82	1	171	53	237	2.1e-31	105.9	COG2114	Adenylate cyclase, class 3	227
2852596718	881	98.31	191	603	3	409	1.5e-87	290	COG3903	Predicted ATPase	414
2852596719	446	42.04	239	439	8	168	4.7e-35	25.1	COG0477	MFS family permease	338
2852596719	446	51.44	17	233	5	201	4.7e-35	99.2	COG0477	MFS family permease	338
2852596720	452	89.11	5	448	16	375	4.3e-67	223.2	COG1680	CubicO group peptidase, beta-lactamase class C family	390
2852596721	360	29.9	21	261	93	179	1.9e-03	13.1	COG1426	Cytoskeletal protein RodZ, contains Xre-like HTH and DUF4115 domains	284
2852596724	67	98.51	1	67	1	66	5.8e-34	112.5	COG1278	Cold shock protein, CspA family	67
2852596728	365	67.73	2	360	122	398	3.6e-21	72.9	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2852596730	507	74.44	230	495	78	310	1.2e-45	152.1	COG2152	Predicted glycosyl hydrolase, GH43/DUF377 family	314
2852596732	85	61.82	1	78	38	105	8.2e-05	19.5	COG1544	Ribosome-associated translation inhibitor RaiA	110
2852596733	395	95.68	10	387	3	356	1.1e-25	85.1	COG0686	Alanine dehydrogenase	371
2852596735	454	97.41	61	427	5	342	2.8e-63	210.4	COG3239	Fatty acid desaturase	343
2852596736	47	7.9	1	46	58	100	1.3e-03	13.8	COG1178	ABC-type Fe3+ transport system, permease component	540
2852596739	220	33.95	101	215	56	110	8.4e-04	15.9	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2852596742	151	87.5	7	130	6	124	1.4e-07	27.9	COG3631	Ketosteroid isomerase-related protein	133
2852596745	669	77.55	8	300	16	312	4.3e-15	51.7	COG0477	MFS family permease	338
2852596745	669	93.71	504	647	8	156	4.9e-16	55.1	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2852596746	330	90.31	1	210	18	222	4.2e-24	81.3	COG5012	Methanogenic corrinoid protein MtbC1	227
2852596747	422	64.4	156	422	130	366	9.4e-40	133.1	COG2208	Serine phosphatase RsbU, regulator of sigma subunit	367
2852596748	257	14.1	154	246	397	471	2.3e-07	14.5	COG5651	PPE-repeat protein	490
2852596748	257	37.03	9	206	334	530	2.3e-07	26.9	COG5651	PPE-repeat protein	490
2852596749	508	43.34	253	495	5	170	3.1e-26	16.1	COG0477	MFS family permease	338
2852596749	508	81.46	5	281	5	316	3.1e-26	76.7	COG0477	MFS family permease	338
2852596751	471	93.55	13	192	5	178	1.5e-28	95.9	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2852596754	148	23.73	2	146	224	293	1.2e-04	18.7	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852596755	317	18.55	1	95	9	72	7.4e-50	46.3	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
2852596755	317	56.52	78	317	134	328	7.4e-50	124.2	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
2852596756	83	18.16	2	81	119	193	8.1e-03	11.7	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
2852596757	270	91.86	3	267	22	292	2.8e-27	92.5	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852596758	375	66.24	9	288	4	260	4.7e-17	58.2	COG1748	Saccharopine dehydrogenase, NADP-dependent	389
2852596759	155	97.95	11	137	2	144	3.7e-11	40.5	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2852596760	1120	96.83	1	1112	12	1080	6.9e-123	408	COG4913	Uncharacterized protein YPO0396	1104
2852596761	187	74.16	4	187	18	172	3.2e-10	37.3	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852596762	736	94.43	3	394	20	392	1.9e-06	22.7	COG2814	Predicted arabinose efflux permease, MFS family	394
2852596762	736	98.31	405	734	5	294	4.2e-37	125.1	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852596763	411	87.67	8	393	1	377	4.5e-49	164.4	COG0446	NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase	415
2852596764	62	100	1	62	1	68	2.4e-16	56.3	COG1141	Ferredoxin	68
2852596765	321	97.14	3	291	9	280	1.1e-79	264.2	COG3687	Predicted metal-dependent hydrolase	280
2852596769	481	13.09	137	230	128	152	2.0e-02	3.7	COG4420	Uncharacterized membrane protein	191
2852596769	481	34.03	236	325	110	174	2.0e-02	7.7	COG4420	Uncharacterized membrane protein	191
2852596773	129	47.69	2	125	20	81	1.1e-07	29.3	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2852596774	676	73.1	2	426	33	388	6.6e-63	209.5	COG1061	Superfamily II DNA or RNA helicase	442
2852596777	381	98.45	1	381	2	381	1.4e-105	350	COG1104	Cysteine sulfinate desulfinase/cysteine desulfurase or related enzyme	386
2852596779	1147	11.67	52	235	57	86	1.2e-02	6.2	COG1119	ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA	257
2852596781	532	73.72	89	516	32	390	1.9e-57	191.5	COG1061	Superfamily II DNA or RNA helicase	442
2852596790	66	3.53	15	62	685	710	7.1e-05	18	COG0507	ATP-dependent exoDNAse (exonuclease V), alpha subunit, helicase superfamily I	696
2852596792	361	94.12	150	348	8	183	6.7e-19	64.5	COG3172	Nicotinamide riboside kinase	187
2852596793	220	88.29	3	213	16	211	1.7e-33	112.4	COG3201	Nicotinamide riboside transporter PnuC	222
2852596794	482	40.88	317	479	72	145	7.0e-09	31.4	COG2453	Protein-tyrosine phosphatase	180
2852596794	482	94.27	1	310	2	297	3.5e-35	116.9	COG1397	ADP-ribosylglycohydrolase	314
2852596795	216	95.21	12	182	6	144	1.5e-22	76.5	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
2852596801	95	97.94	1	95	2	96	7.0e-11	38.8	COG4842	Uncharacterized conserved protein YukE	97
2852596802	100	91.75	1	97	4	92	3.5e-14	49.4	COG4842	Uncharacterized conserved protein YukE	97
2852596803	747	11.04	1	116	367	470	7.4e-103	20.8	COG2409	Uncharacterized membrane protein YdfJ, MMPL/SSD domain	937
2852596803	747	63.06	116	726	166	759	7.4e-103	323.1	COG2409	Uncharacterized membrane protein YdfJ, MMPL/SSD domain	937
2852596804	341	72.56	68	333	86	323	2.3e-22	75.6	COG0142	Geranylgeranyl pyrophosphate synthase	322
2852596805	132	33.58	2	119	21	66	1.8e-04	17.9	COG4319	Ketosteroid isomerase homolog	137
2852596807	336	78.38	2	333	91	420	3.1e-70	233.5	COG2124	Cytochrome P450	411
2852596808	886	65.77	780	877	31	103	1.1e-15	52.9	COG3848	Phosphohistidine swiveling domain of PEP-utilizing enzymes	111
2852596809	207	95.24	34	207	8	187	1.5e-18	64.1	COG2020	Protein-S-isoprenylcysteine O-methyltransferase Ste14	187
2852596811	340	91.16	24	340	28	326	2.0e-53	177.9	COG0142	Geranylgeranyl pyrophosphate synthase	322
2852596813	640	31.74	11	218	4	202	0.0e+00	303.6	COG1154	Deoxyxylulose-5-phosphate synthase	627
2852596813	640	62.2	213	607	234	623	0.0e+00	433.4	COG1154	Deoxyxylulose-5-phosphate synthase	627
2852596816	181	72.73	1	181	13	164	2.1e-14	51	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852596819	159	46	74	143	14	59	1.1e-02	12	COG3657	Putative component of the toxin-antitoxin plasmid stabilization module	100
2852596822	204	82.35	3	196	5	144	2.7e-25	85.6	COG0262	Dihydrofolate reductase	167
2852596823	153	63.13	2	147	74	210	3.0e-22	75.6	COG5637	Uncharacterized membrane protein	217
2852596824	278	90.48	36	278	22	249	9.4e-63	208.5	COG1191	DNA-directed RNA polymerase specialized sigma subunit	247
2852596825	436	97.3	1	428	3	399	7.5e-43	142	COG1819	UDP:flavonoid glycosyltransferase YjiC, YdhE family	406
2852596826	260	68.75	19	190	27	125	1.9e+00	9.4	COG3152	Uncharacterized membrane protein YhaH, DUF805 family	125
2852596829	217	95.22	10	217	5	203	1.6e-19	67.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852596830	205	49.65	4	203	75	216	1.2e-08	30.8	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
2852596832	356	97.23	9	347	6	321	1.5e-88	292.7	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
2852596835	206	55.22	28	74	15	51	8.7e-03	12	COG1582	Uncharacterized protein YlzI, FlbEa/FlbD family	67
2852596839	166	81.32	39	127	10	83	1.3e-07	27.9	COG2732	Barstar, RNAse (barnase) inhibitor	91
2852596842	267	50.89	5	235	127	298	1.1e-25	87.5	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
2852596843	427	73.27	1	425	27	407	1.2e-118	393.5	COG0513	Superfamily II DNA and RNA helicase	513
2852596846	67	98.51	1	67	1	66	1.0e-35	118.2	COG1278	Cold shock protein, CspA family	67
2852596849	320	59.66	27	315	159	402	3.8e-20	69.6	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2852596852	266	47.85	16	262	79	234	1.7e-06	24.2	COG2203	GAF domain	175
2852596853	544	90.14	10	539	41	552	3.7e-78	259.5	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2852596854	541	98.3	17	539	7	525	0.0e+00	637.3	COG4108	Peptide chain release factor RF-3	528
2852596856	546	94.09	13	189	4	178	2.3e-29	98.5	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2852596858	951	98.83	10	943	5	935	0.0e+00	968.2	COG2409	Uncharacterized membrane protein YdfJ, MMPL/SSD domain	937
2852596860	214	86.36	90	210	13	107	3.2e-31	104	COG5586	Uncharacterized protein	110
2852596861	504	51.7	270	494	9	206	7.4e-35	28.1	COG0477	MFS family permease	338
2852596861	504	55.61	24	276	3	215	7.4e-35	94.4	COG0477	MFS family permease	338
2852596863	525	95.71	1	475	11	478	6.5e-87	283.7	COG0069	Glutamate synthase domain 2	485
2852596865	337	89.8	3	335	18	325	1.0e-35	119.8	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852596869	172	86.86	9	167	5	156	7.1e-71	233.8	COG3479	Phenolic acid decarboxylase	175
2852596870	254	48.25	52	251	23	146	1.2e-05	21.6	COG3319	Thioesterase domain of type I polyketide synthase or non-ribosomal peptide synthetase	257
2852596871	422	87.6	128	396	29	240	2.3e-29	99.9	COG1376	Lipoprotein-anchoring transpeptidase ErfK/SrfK	232
2852596873	535	32.56	78	295	162	401	1.0e-94	134.4	COG0507	ATP-dependent exoDNAse (exonuclease V), alpha subunit, helicase superfamily I	696
2852596873	535	40.03	284	535	435	729	1.0e-94	178.8	COG0507	ATP-dependent exoDNAse (exonuclease V), alpha subunit, helicase superfamily I	696
2852596874	1061	15.71	10	186	11	191	0.0e+00	106.6	COG1074	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)	1139
2852596874	1061	71.53	181	1031	329	1152	0.0e+00	563.9	COG1074	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)	1139
2852596875	1078	97.31	2	1070	2	1051	0.0e+00	862.6	COG1330	Exonuclease V gamma subunit	1078
2852596876	200	20.03	2	171	25	169	1.0e-24	83.2	COG0317	(p)ppGpp synthase/hydrolase, HD superfamily	701
2852596878	389	100	1	379	1	353	2.1e-82	273	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
2852596879	301	97.29	27	300	6	292	4.3e-33	111.6	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852596883	371	84.65	5	365	1	364	8.9e-53	176.6	COG0446	NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase	415
2852596884	327	92.68	13	327	25	328	1.9e-54	181.1	COG0598	Mg2+ and Co2+ transporter CorA	322
2852596885	251	47.09	151	241	99	187	6.3e-40	67.2	COG2020	Protein-S-isoprenylcysteine O-methyltransferase Ste14	187
2852596885	251	70.9	13	157	1	134	6.3e-40	72	COG2020	Protein-S-isoprenylcysteine O-methyltransferase Ste14	187
2852596886	513	10.51	21	63	159	195	1.6e-63	9.9	COG2206	HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant)	344
2852596886	513	28.41	125	231	217	316	1.6e-63	31.3	COG2206	HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant)	344
2852596886	513	50.28	230	454	147	323	1.6e-63	167.9	COG2206	HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant)	344
2852596890	194	84.21	1	194	7	182	1.1e-18	65.3	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852596891	233	88.68	1	233	5	239	1.1e-35	119.8	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2852596893	777	63.95	281	773	218	641	4.5e-92	304.7	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2852596894	336	57.68	1	252	31	274	3.5e-26	86.1	COG3673	Uncharacterized protein, PA2063/DUF2235 family	423
2852596897	236	78.46	7	226	21	224	3.3e-45	151.1	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2852596898	287	39.06	31	195	99	173	1.7e-07	27.3	COG1432	Uncharacterized conserved protein, LabA/DUF88 family	181
2852596902	55	96.08	5	55	3	51	3.4e-26	87.9	COG0267	Ribosomal protein L33	50
2852596903	159	30.82	4	145	99	147	4.7e-05	18.5	COG2030	Acyl dehydratase	159
2852596904	142	88.05	1	137	16	155	1.4e-26	89.1	COG2030	Acyl dehydratase	159
2852596905	175	79.25	2	144	23	148	9.8e-07	24.2	COG2030	Acyl dehydratase	159
2852596907	147	87.67	74	144	9	72	6.3e-21	70	COG0690	Preprotein translocase subunit SecE	73
2852596908	276	97.81	85	276	4	182	1.2e-59	197.2	COG0250	Transcription antitermination factor NusG	178
2852596909	142	97.87	4	142	2	139	5.8e-66	217.3	COG0080	Ribosomal protein L11	141
2852596910	235	99.57	1	227	1	229	2.6e-94	311.6	COG0081	Ribosomal protein L1	228
2852596911	108	60.94	46	100	19	57	1.5e-02	8.5	COG3411	(2Fe-2S) ferredoxin	64
2852596912	927	6.38	832	915	826	882	1.3e-17	31	COG2909	ATP-, maltotriose- and DNA-dependent transcriptional regulator MalT	894
2852596912	927	11.3	706	840	505	605	1.3e-17	12.7	COG2909	ATP-, maltotriose- and DNA-dependent transcriptional regulator MalT	894
2852596912	927	11.52	416	551	449	551	1.3e-17	11.9	COG2909	ATP-, maltotriose- and DNA-dependent transcriptional regulator MalT	894
2852596912	927	15.32	554	708	508	644	1.3e-17	8.3	COG2909	ATP-, maltotriose- and DNA-dependent transcriptional regulator MalT	894
2852596912	927	23.6	106	359	119	329	1.3e-17	5.1	COG2909	ATP-, maltotriose- and DNA-dependent transcriptional regulator MalT	894
2852596913	279	38.43	4	271	131	213	2.7e-04	13.3	COG0778	Nitroreductase	207
2852596915	512	96	286	512	4	219	7.3e-69	225.1	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
2852596916	400	69.68	3	369	88	372	5.6e-21	72.3	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2852596917	341	98.55	4	331	2	340	2.6e-117	387.1	COG1089	GDP-D-mannose dehydratase	345
2852596918	316	95.64	1	297	6	312	1.3e-50	169.2	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2852596919	483	85.31	218	469	27	270	2.7e-55	183.3	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
2852596920	138	54.73	1	129	62	142	1.8e-12	44	COG0394	Protein-tyrosine-phosphatase	139
2852596923	304	89.78	22	295	5	285	1.5e-41	138.7	COG1216	Glycosyltransferase, GT2 family	305
2852596925	349	64.51	32	342	86	334	4.2e-22	74.5	COG2327	Polysaccharide pyruvyl transferase family protein WcaK	385
2852596926	415	86.01	15	364	3	291	1.7e-30	102.6	COG1035	Coenzyme F420-reducing hydrogenase, beta subunit	332
2852596927	343	68.05	1	335	84	411	2.5e-25	85.5	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
2852596929	301	74.55	33	300	45	252	5.1e-09	33.2	COG0500	SAM-dependent methyltransferase	257
2852596930	395	70.9	28	391	97	386	1.9e-32	109.9	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2852596934	492	97.33	266	492	4	222	1.1e-71	236.6	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
2852596937	254	93.21	44	251	12	217	7.4e-16	55	COG2755	Lysophospholipase L1 or related esterase	216
2852596938	247	81.42	11	212	12	195	5.7e-25	84.3	COG3944	Capsular polysaccharide biosynthesis protein	226
2852596939	267	25.07	1	210	4	93	1.5e-16	58.2	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2852596940	413	80.29	13	409	16	402	9.3e-07	22.1	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
2852596941	470	83.22	13	432	34	390	6.2e-05	14.9	COG3307	O-antigen ligase	424
2852596942	463	99.52	2	423	2	417	1.9e-90	299.9	COG1004	UDP-glucose 6-dehydrogenase	414
2852596943	415	96.82	3	405	11	406	1.8e-21	73.9	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2852596944	412	98.13	79	399	3	317	3.3e-60	200.6	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2852596946	238	91.89	60	227	4	139	2.1e-28	95.2	COG0394	Protein-tyrosine-phosphatase	139
2852596947	774	94.86	3	329	2	333	6.8e-34	113.6	COG1088	dTDP-D-glucose 4,6-dehydratase	340
2852596947	774	99.04	334	760	2	415	0.0e+00	457.1	COG1004	UDP-glucose 6-dehydrogenase	414
2852596948	350	86.67	119	350	31	225	3.8e-74	245	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
2852596950	285	67.73	1	209	9	220	1.1e-20	70.1	COG1216	Glycosyltransferase, GT2 family	305
2852596951	423	95.18	2	422	10	424	0.0e+00	456.9	COG0677	UDP-N-acetyl-D-mannosaminuronate dehydrogenase	436
2852596953	403	86.48	3	388	20	390	5.2e-06	19.6	COG3307	O-antigen ligase	424
2852596954	247	93.28	1	243	11	246	3.1e-68	226	COG1922	UDP-N-acetyl-D-mannosaminuronic acid transferase, WecB/TagA/CpsF family	253
2852596955	116	31.46	7	111	217	317	7.8e-14	48.4	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2852596956	304	54.47	31	269	14	147	5.4e-05	17.7	COG2120	N-acetylglucosaminyl deacetylase, LmbE family	237
2852596957	240	47.19	5	236	210	402	4.9e-25	85.6	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2852596959	471	94.61	1	456	16	471	8.8e-32	106.5	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
2852596960	368	74.82	5	362	89	394	5.7e-18	62.3	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2852596962	336	90.4	1	335	33	371	1.3e-102	340.2	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
2852596963	334	98.44	5	325	4	319	1.5e-64	215	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2852596966	471	73.08	233	463	42	250	2.9e-40	133.5	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
2852596966	471	95.58	1	228	8	223	2.7e-43	143.9	COG3944	Capsular polysaccharide biosynthesis protein	226
2852596969	313	98.58	36	313	2	279	2.6e-68	226.5	COG1091	dTDP-4-dehydrorhamnose reductase	281
2852596970	131	28.87	12	131	133	214	3.4e-06	23.3	COG2801	Transposase InsO and inactivated derivatives	232
2852596971	910	66.25	837	904	18	70	1.6e-15	51.5	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2852596974	292	45.96	1	232	5	169	2.9e-14	50.5	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2852596975	428	83.2	17	427	6	406	6.0e-14	46.4	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
2852596976	557	71.88	94	332	5	229	4.4e-15	51.5	COG1216	Glycosyltransferase, GT2 family	305
2852596980	401	93.78	1	396	7	398	3.4e-65	217	COG4102	Uncharacterized conserved protein, DUF1501 family	418
2852596981	442	68.95	11	403	119	460	1.7e-55	185.1	COG5267	Uncharacterized conserved protein, DUF1800 family	496
2852596983	240	65.2	9	194	54	216	5.0e-15	51.4	COG4424	LPS sulfotransferase NodH	250
2852596984	466	80.71	46	451	8	396	8.3e-20	67.1	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
2852596985	540	10.56	397	539	496	555	1.5e-15	15.9	COG2303	Choline dehydrogenase or related flavoprotein	542
2852596985	540	49.82	6	360	8	290	1.5e-15	37.8	COG2303	Choline dehydrogenase or related flavoprotein	542
2852596986	281	72.59	1	237	4	236	6.7e-24	81.3	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2852596987	597	11.44	153	264	227	291	1.2e-35	14.6	COG2303	Choline dehydrogenase or related flavoprotein	542
2852596987	597	24.12	400	575	423	559	1.2e-35	60.1	COG2303	Choline dehydrogenase or related flavoprotein	542
2852596987	597	24.47	10	150	6	144	1.2e-35	42	COG2303	Choline dehydrogenase or related flavoprotein	542
2852596988	397	76.04	86	374	4	241	2.7e-07	24.9	COG1216	Glycosyltransferase, GT2 family	305
2852596989	331	64.22	8	239	8	208	8.8e-10	33.3	COG1216	Glycosyltransferase, GT2 family	305
2852596990	414	91.77	13	393	11	367	8.0e-85	281.4	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
2852596994	308	80.32	9	305	57	305	8.7e-13	43.3	COG3021	Uncharacterized conserved protein YafD, endonuclease/exonuclease/phosphatase (EEP) superfamily	309
2852596995	404	96.33	16	397	12	405	1.4e-38	129.8	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2852596996	257	56.27	26	248	11	176	7.5e-06	22.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852596998	451	98.57	4	433	6	420	4.6e-93	308.8	COG2124	Cytochrome P450	411
2852596999	239	75.63	3	237	45	255	3.4e-19	66.1	COG0500	SAM-dependent methyltransferase	257
2852597000	312	94.84	1	307	9	302	5.2e-18	61.8	COG3021	Uncharacterized conserved protein YafD, endonuclease/exonuclease/phosphatase (EEP) superfamily	309
2852597001	405	98.07	1	405	6	412	2.8e-127	421.4	COG4941	Predicted RNA polymerase sigma factor, contains C-terminal TPR domain	415
2852597002	235	60.16	131	234	40	113	1.3e-40	56.5	COG3795	Uncharacterized conserved protein	123
2852597002	235	93.5	1	117	1	115	1.3e-40	77.1	COG3795	Uncharacterized conserved protein	123
2852597004	298	96.15	3	293	11	285	2.2e-99	328.6	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
2852597005	298	97.2	1	293	8	285	2.6e-101	335	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
2852597006	286	95.8	1	286	13	286	1.3e-115	382	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
2852597007	289	97.55	1	289	8	286	6.1e-119	392.9	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
2852597008	300	98.64	4	300	3	293	1.0e-39	133.5	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852597009	448	86.13	1	448	11	451	0.0e+00	450.4	COG0661	Predicted unusual protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family	517
2852597010	430	52.22	235	429	8	207	1.5e-31	18.7	COG0477	MFS family permease	338
2852597010	430	71.54	8	269	5	278	1.5e-31	90.4	COG0477	MFS family permease	338
2852597012	292	91.19	1	290	9	277	3.2e-42	141.6	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852597014	203	49.42	24	163	28	112	4.6e-03	12.9	COG2318	Uncharacterized damage-inducible protein DinB (forms a four-helix bundle)	172
2852597016	317	96.49	2	317	7	308	3.5e-57	190.8	COG2378	Predicted DNA-binding transcriptional regulator YafY, contains an HTH and WYL domains	311
2852597018	255	96.89	1	255	6	254	3.0e-25	81.9	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
2852597019	1387	6.43	1057	1125	929	992	3.0e-116	4.2	COG0383	Alpha-mannosidase	943
2852597019	1387	9.55	132	238	253	347	3.0e-116	12.7	COG0383	Alpha-mannosidase	943
2852597019	1387	21.51	1130	1386	781	994	3.0e-116	20.5	COG0383	Alpha-mannosidase	943
2852597019	1387	70.25	225	1064	7	705	3.0e-116	346	COG0383	Alpha-mannosidase	943
2852597021	300	94.84	1	300	7	300	6.4e-70	232.3	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
2852597022	190	97.16	1	171	3	173	6.1e-51	169	COG0244	Ribosomal protein L10	175
2852597023	130	99.2	2	130	2	125	9.1e-46	151.9	COG0222	Ribosomal protein L7/L12	124
2852597024	359	95.82	2	259	9	260	1.5e-97	322.3	COG1127	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, ATPase component MlaF	263
2852597025	717	13.33	530	708	679	786	6.8e-91	54.9	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2852597025	717	61.48	1	486	60	557	6.8e-91	245.6	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2852597026	1151	11.07	847	995	592	690	0.0e+00	23.3	COG2909	ATP-, maltotriose- and DNA-dependent transcriptional regulator MalT	894
2852597026	1151	54.59	323	846	5	492	0.0e+00	510	COG2909	ATP-, maltotriose- and DNA-dependent transcriptional regulator MalT	894
2852597027	544	26.44	204	498	84	161	1.4e-03	15.8	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852597028	939	74.53	260	534	62	298	6.5e-32	105.8	COG0657	Acetyl esterase/lipase	312
2852597029	1161	98.9	6	1126	11	1084	0.0e+00	1445.7	COG0085	DNA-directed RNA polymerase, beta subunit/140 kD subunit	1060
2852597030	1317	5.18	979	1046	419	460	0.0e+00	20	COG0086	DNA-directed RNA polymerase, beta' subunit/160 kD subunit	808
2852597030	1317	6.66	1194	1268	690	743	0.0e+00	15.3	COG0086	DNA-directed RNA polymerase, beta' subunit/160 kD subunit	808
2852597030	1317	98.64	5	933	5	804	0.0e+00	912.6	COG0086	DNA-directed RNA polymerase, beta' subunit/160 kD subunit	808
2852597032	250	96.81	1	250	4	276	9.3e-59	195.5	COG0648	Endonuclease IV	280
2852597034	152	66.67	32	137	15	92	2.2e-08	30.2	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
2852597035	114	95.28	1	113	6	126	6.6e-19	65	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
2852597036	121	44.53	4	121	70	126	3.9e-11	38.6	COG3603	Uncharacterized protein	128
2852597037	76	11.4	18	74	150	202	6.5e-03	11.6	COG2211	Na+/melibiose symporter or related transporter	467
2852597038	542	96.74	22	441	8	393	2.0e-69	231.3	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852597039	312	97.36	10	296	6	263	1.9e-69	230.4	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2852597040	244	86.94	2	244	7	259	1.2e-63	211.8	COG3327	DNA-binding transcriptional regulator PaaX (phenylacetic acid degradation)	291
2852597041	255	95.47	2	253	7	259	8.0e-63	208.6	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2852597046	194	92.82	1	194	7	200	8.9e-13	46.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852597047	124	95.35	1	123	7	129	4.9e-60	197.3	COG0048	Ribosomal protein S12	129
2852597048	156	99.32	2	149	2	148	3.0e-60	198.7	COG0049	Ribosomal protein S7	148
2852597049	701	98.49	3	701	6	723	0.0e+00	972.6	COG0480	Translation elongation factor EF-G, a GTPase	697
2852597050	396	99.75	1	396	2	394	0.0e+00	715.3	COG0050	Translation elongation factor EF-Tu, a GTPase	394
2852597054	457	47.78	250	456	8	190	3.4e-38	12.5	COG0477	MFS family permease	338
2852597054	457	82.77	8	295	3	319	3.4e-38	122.1	COG0477	MFS family permease	338
2852597056	480	93.5	1	469	11	470	6.6e-69	229.2	COG0531	Amino acid transporter	466
2852597057	413	99.02	4	413	4	406	0.0e+00	472.3	COG2235	Arginine deiminase	409
2852597058	284	98.88	6	282	2	266	4.4e-64	213.1	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852597059	293	81.13	15	144	28	156	1.9e-28	39.7	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2852597059	293	88.05	147	293	17	156	1.9e-28	60.3	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2852597060	511	93.7	24	482	7	467	1.7e-91	303.6	COG0531	Amino acid transporter	466
2852597061	414	97.28	1	409	7	400	0.0e+00	449.2	COG4992	Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase	404
2852597062	270	98.88	8	268	3	267	2.5e-71	236.4	COG1834	N-Dimethylarginine dimethylaminohydrolase	267
2852597063	148	94.94	1	146	3	152	4.4e-31	104.4	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2852597064	391	90.47	7	390	1	389	4.6e-75	250	COG0446	NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase	415
2852597065	429	40.88	359	427	71	126	1.0e-33	19.2	COG2764	Uncharacterized conserved protein PhnB, glyoxalase superfamily	136
2852597065	429	95.62	73	199	3	133	1.0e-33	89.9	COG2764	Uncharacterized conserved protein PhnB, glyoxalase superfamily	136
2852597066	174	88.71	4	172	14	178	7.4e-27	90.5	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2852597067	218	89.47	16	215	8	194	5.0e-21	72.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852597070	389	95.53	4	349	12	353	7.6e-81	268.3	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
2852597071	397	96.12	10	389	4	350	1.5e-99	329.6	COG1304	FMN-dependent dehydrogenase, includes L-lactate dehydrogenase and type II isopentenyl diphosphate isomerase	360
2852597072	239	95.18	4	236	10	246	1.3e-62	207.9	COG1402	 Creatinine amidohydrolase/Fe(II)-dependent formamide hydrolase involved in riboflavin and F420 biosynthesis	250
2852597073	470	61.34	102	351	59	250	4.8e-14	48.3	COG1216	Glycosyltransferase, GT2 family	305
2852597074	471	96.13	1	469	10	555	3.3e-84	268.8	COG2303	Choline dehydrogenase or related flavoprotein	542
2852597075	552	94.52	21	397	7	368	8.1e-23	75.7	COG0477	MFS family permease	338
2852597076	208	92.34	1	207	7	199	4.6e-18	63.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852597077	431	94.06	14	429	24	419	3.0e-86	286.3	COG2124	Cytochrome P450	411
2852597078	529	98.79	40	529	4	491	3.4e-121	402.2	COG2272	Carboxylesterase type B	491
2852597079	119	32.14	3	84	7	42	3.3e-05	20.2	COG4538	Uncharacterized protein	112
2852597080	637	88.14	1	312	30	304	6.3e-24	80.9	COG0501	Zn-dependent protease with chaperone function	302
2852597081	117	84.62	1	115	8	117	7.2e-21	71	COG4308	Limonene-1,2-epoxide hydrolase	130
2852597083	101	96.15	1	101	2	101	5.4e-45	148.3	COG0051	Ribosomal protein S10	104
2852597084	217	97.8	3	217	2	223	2.2e-79	262.9	COG0087	Ribosomal protein L3	218
2852597085	228	97.24	5	220	3	213	8.7e-70	230.8	COG0088	Ribosomal protein L4	214
2852597086	100	96.81	7	99	2	92	2.0e-33	111.4	COG0089	Ribosomal protein L23	94
2852597087	280	99.64	1	274	1	274	6.3e-122	402.7	COG0090	Ribosomal protein L2	275
2852597088	93	98.92	1	93	1	92	2.6e-43	142.4	COG0185	Ribosomal protein S19	93
2852597089	190	93.29	1	120	8	146	5.4e-42	140	COG0091	Ribosomal protein L22	120
2852597090	285	91.85	12	248	1	214	2.5e-89	295	COG0092	Ribosomal protein S3	233
2852597091	138	93.96	1	138	2	141	5.0e-57	188.4	COG0197	Ribosomal protein L16/L10AE	146
2852597092	77	86.76	1	70	7	65	9.3e-28	92.7	COG0255	Ribosomal protein L29	69
2852597093	98	96.55	13	98	3	86	6.4e-36	118.7	COG0186	Ribosomal protein S17	87
2852597097	491	66.73	67	470	59	395	1.7e-54	181.7	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
2852597098	560	40.77	26	419	114	336	2.4e-02	9.8	COG1807	4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family	535
2852597099	506	98.56	25	499	6	484	0.0e+00	470.4	COG0364	Glucose-6-phosphate 1-dehydrogenase	483
2852597100	248	60.57	8	237	55	223	4.1e-06	23.8	COG0500	SAM-dependent methyltransferase	257
2852597101	233	78.47	17	231	9	172	7.0e-14	47.3	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852597102	228	67.94	44	166	16	104	2.8e-06	23.9	COG5395	Uncharacterized membrane protein	131
2852597103	781	98.98	26	582	4	486	0.0e+00	539.3	COG3119	Arylsulfatase A or related enzyme	475
2852597105	292	79.58	1	292	67	331	2.3e-81	270.2	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
2852597106	256	96.23	1	254	4	258	2.3e-57	190.6	COG0300	Short-chain dehydrogenase	265
2852597108	122	100	1	122	1	123	1.9e-56	185.9	COG0093	Ribosomal protein L14	122
2852597109	105	97.22	1	105	3	107	2.0e-34	114.7	COG0198	Ribosomal protein L24	104
2852597110	187	98.89	8	187	2	179	4.4e-79	260.8	COG0094	Ribosomal protein L5	180
2852597111	61	100	1	61	1	61	1.2e-29	98.6	COG0199	Ribosomal protein S14	61
2852597112	132	100	1	132	1	133	1.8e-49	163.5	COG0096	Ribosomal protein S8	132
2852597113	179	100	1	179	1	179	3.7e-66	218.7	COG0097	Ribosomal protein L6P/L9E	178
2852597114	134	96.03	15	134	6	126	7.0e-39	129.6	COG0256	Ribosomal protein L18	125
2852597115	221	86.41	26	198	23	181	3.7e-66	218.2	COG0098	Ribosomal protein S5	181
2852597116	59	100	4	58	1	55	5.8e-24	80.1	COG1841	Ribosomal protein L30/L7E	55
2852597117	146	98.7	3	146	1	152	1.4e-42	142	COG0200	Ribosomal protein L15	152
2852597119	310	87.46	8	307	23	322	1.1e-50	168.9	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852597120	116	86.76	2	115	10	127	5.3e-07	26.1	COG3631	Ketosteroid isomerase-related protein	133
2852597121	598	60.94	54	290	85	279	3.7e-104	59.9	COG0616	Periplasmic serine protease, ClpP class	317
2852597121	598	82.5	273	588	44	307	3.7e-104	287.3	COG0616	Periplasmic serine protease, ClpP class	317
2852597122	254	86.79	3	246	4	233	5.6e-53	176.1	COG0300	Short-chain dehydrogenase	265
2852597123	403	96.03	17	402	15	353	4.6e-69	229.2	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
2852597124	282	79.55	141	282	21	125	1.7e-27	88.7	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2852597125	220	60.25	19	198	21	164	1.4e-27	92.7	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
2852597126	218	87.95	5	213	11	207	4.3e-57	189.6	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
2852597127	325	96.93	1	325	5	320	2.0e-85	283	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
2852597128	440	96.61	2	439	4	488	2.6e-67	223.2	COG1070	Sugar (pentulose or hexulose) kinase	502
2852597129	219	78.47	1	210	5	168	7.2e-24	82	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852597131	716	5.83	511	575	277	301	2.4e-07	4.8	COG0823	Periplasmic component of the Tol biopolymer transport system	425
2852597131	716	13.29	195	306	224	280	2.4e-07	6.6	COG0823	Periplasmic component of the Tol biopolymer transport system	425
2852597131	716	14.22	344	471	244	304	2.4e-07	11.7	COG0823	Periplasmic component of the Tol biopolymer transport system	425
2852597135	299	98	2	299	1	294	7.5e-89	294.3	COG3315	O-Methyltransferase involved in polyketide biosynthesis	297
2852597136	299	94	2	293	2	283	4.8e-92	304.7	COG3315	O-Methyltransferase involved in polyketide biosynthesis	297
2852597137	298	97.33	2	297	2	293	2.9e-93	308.7	COG3315	O-Methyltransferase involved in polyketide biosynthesis	297
2852597138	311	93.67	2	305	2	282	6.2e-100	330.6	COG3315	O-Methyltransferase involved in polyketide biosynthesis	297
2852597139	421	92.05	1	421	30	434	0.0e+00	459.4	COG0201	Preprotein translocase subunit SecY	436
2852597140	182	98.92	1	181	2	184	5.2e-70	231.9	COG0563	Adenylate kinase or related kinase	178
2852597141	265	96.77	11	265	6	305	3.0e-72	239.7	COG0024	Methionine aminopeptidase	255
2852597142	171	89.78	2	171	15	181	6.7e-43	143	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2852597144	565	97.3	5	549	5	544	5.2e-93	308.6	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
2852597146	339	98.77	4	337	4	325	5.5e-43	143.6	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
2852597147	345	92.52	4	345	24	357	2.6e-85	282.9	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
2852597148	167	75.19	31	162	15	114	3.6e-16	55.7	COG1846	DNA-binding transcriptional regulator, MarR family	126
2852597149	201	94.74	1	200	6	203	2.9e-24	83.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852597150	281	96.27	1	278	7	290	1.1e-31	107.1	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852597151	408	61.07	18	401	147	375	4.8e-59	197	COG4585	Signal transduction histidine kinase	365
2852597152	221	98.58	8	221	2	209	3.8e-60	199.6	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2852597153	268	94.57	28	262	2	210	1.3e-22	77.1	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
2852597154	408	86.63	7	406	42	391	1.9e-51	171.9	COG1680	CubicO group peptidase, beta-lactamase class C family	390
2852597155	267	60.06	4	222	17	222	7.8e-35	116.2	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852597157	291	100	2	289	1	286	5.5e-96	317.6	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
2852597158	388	97.99	2	386	3	393	5.0e-119	394.4	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852597159	505	99.37	5	493	2	477	0.0e+00	543.2	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2852597160	110	71.19	8	110	16	99	4.5e-12	42.8	COG0640	DNA-binding transcriptional regulator, ArsR family	110
2852597161	287	98.63	1	285	4	291	1.1e-58	195.7	COG0384	Predicted epimerase YddE/YHI9, PhzF superfamily	291
2852597162	320	94.85	2	319	6	318	2.0e-70	234	COG2423	Ornithine cyclodeaminase/archaeal alanine dehydrogenase, mu-crystallin family	330
2852597163	267	95.85	1	261	6	259	6.6e-66	218.8	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2852597164	200	97.18	2	178	6	177	1.8e-60	199.8	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase or related enzyme	173
2852597165	331	99.14	1	331	1	347	0.0e+00	457.1	COG1088	dTDP-D-glucose 4,6-dehydratase	340
2852597166	280	86.3	6	274	21	316	1.1e-19	59.6	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852597167	278	34.99	2	129	19	138	8.7e-22	46.6	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852597167	278	44.02	119	277	173	323	8.7e-22	26.8	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852597168	493	67.01	79	482	129	392	6.8e-44	145.9	COG0642	Signal transduction histidine kinase	336
2852597169	566	57.69	3	132	9	113	7.9e-10	34.8	COG4567	Two-component response regulator, ActR/RegA family, consists of REC and Fis-type HTH domains	182
2852597169	566	98.37	231	566	2	303	1.3e-71	237.5	COG0492	Thioredoxin reductase	305
2852597170	73	96	1	73	1	72	3.2e-36	119.2	COG0361	Translation initiation factor IF-1	75
2852597171	124	100	1	122	1	121	1.5e-51	170.2	COG0099	Ribosomal protein S13	121
2852597172	138	97.69	8	138	4	130	3.6e-61	201.7	COG0100	Ribosomal protein S11	129
2852597173	201	100	1	201	1	210	4.7e-63	209.2	COG0522	Ribosomal protein S4 or related protein	205
2852597174	350	96.87	4	322	7	315	2.1e-119	394.7	COG0202	DNA-directed RNA polymerase, alpha subunit/40 kD subunit	317
2852597175	200	100	1	116	1	116	1.3e-49	163.3	COG0203	Ribosomal protein L17	116
2852597176	289	96.63	12	288	3	260	3.8e-75	249	COG0101	tRNA U38,U39,U40 pseudouridine synthase TruA	266
2852597180	331	96.35	10	314	7	296	7.6e-35	116.9	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2852597181	187	66.33	13	187	62	191	1.0e-15	54.8	COG5516	Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding	196
2852597182	685	9.92	615	678	430	479	9.0e-56	17.3	COG3349	Uncharacterized conserved protein, contains NAD-binding domain and a Fe-S cluster	485
2852597182	685	99.6	6	662	2	503	9.0e-56	175.7	COG3349	Uncharacterized conserved protein, contains NAD-binding domain and a Fe-S cluster	485
2852597183	1067	79.62	550	1066	48	340	2.4e-04	16.1	COG0457	Tetratricopeptide (TPR) repeat	291
2852597183	1067	84.84	6	241	27	233	1.3e-35	119.6	COG2114	Adenylate cyclase, class 3	227
2852597187	350	88.72	12	348	15	305	2.6e-57	190.8	COG0142	Geranylgeranyl pyrophosphate synthase	322
2852597189	249	96.26	147	249	3	105	6.6e-25	83.1	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
2852597192	450	71.96	17	434	98	505	2.6e-49	165.2	COG1404	Serine protease, subtilisin family	508
2852597194	1192	96.89	75	1183	5	907	0.0e+00	533.3	COG1674	DNA segregation ATPase FtsK/SpoIIIE and related proteins	858
2852597196	107	90.72	8	102	7	94	1.1e-17	60.5	COG4842	Uncharacterized conserved protein YukE	97
2852597197	98	93.81	1	98	6	96	2.2e-22	75.7	COG4842	Uncharacterized conserved protein YukE	97
2852597198	97	74.29	2	94	11	88	1.3e-02	12.2	COG4323	Uncharacterized protein	105
2852597201	507	99.16	20	502	2	476	0.0e+00	550.2	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2852597202	353	99.12	14	353	2	339	4.7e-128	423.4	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
2852597204	147	97.3	1	147	3	146	4.3e-57	188.6	COG0102	Ribosomal protein L13	148
2852597205	163	93.98	34	163	9	133	1.2e-47	157.8	COG0103	Ribosomal protein S9	130
2852597208	455	97.07	4	455	10	473	1.3e-129	429.6	COG1109	Phosphomannomutase	464
2852597209	98	32.21	1	95	96	181	8.4e-03	12.1	COG1659	Uncharacterized protein, linocin/CFP29 family	267
2852597210	443	27.37	323	441	60	134	7.6e-01	6.9	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
2852597210	443	28.1	136	301	53	129	7.6e-01	5.4	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
2852597212	476	98.25	31	476	4	451	3.2e-115	382.1	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
2852597215	290	97.34	6	289	2	294	2.7e-48	161.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
2852597216	238	99.25	1	236	1	266	7.0e-38	127.2	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852597221	346	90.09	5	345	19	327	9.9e-47	155.9	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852597223	620	100	1	620	1	615	0.0e+00	759.2	COG0449	Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains	597
2852597224	125	79.65	2	106	17	106	1.5e-18	63.4	COG4828	Uncharacterized membrane protein	113
2852597225	289	99.32	4	286	2	294	4.4e-42	141.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852597226	156	26.02	31	156	142	192	3.3e-15	53.3	COG5516	Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding	196
2852597227	473	96.88	199	473	3	281	1.5e-74	247.7	COG0063	NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate dehydratase domain	284
2852597228	427	84.67	1	427	46	437	0.0e+00	474.5	COG0076	Glutamate or tyrosine decarboxylase or a related PLP-dependent protein	460
2852597229	390	98.9	12	384	4	363	2.1e-110	365.5	COG0787	Alanine racemase	360
2852597230	373	97.97	63	353	5	293	4.6e-37	124.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852597231	165	83.22	17	164	4	127	4.0e-37	123.7	COG0802	tRNA A37 threonylcarbamoyladenosine biosynthesis protein TsaE	149
2852597232	193	66.97	2	190	2	149	8.4e-46	151	COG1214	tRNA A37 threonylcarbamoyladenosine modification protein TsaB	220
2852597233	150	91.53	1	149	11	183	4.0e-33	111.4	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2852597234	341	97.38	2	340	2	336	1.8e-113	375.3	COG0533	tRNA A37 threonylcarbamoyltransferase TsaD	342
2852597236	97	97.92	1	97	2	95	7.4e-40	131.6	COG0234	Co-chaperonin GroES (HSP10)	96
2852597237	541	98.36	1	535	2	542	0.0e+00	532.2	COG0459	Chaperonin GroEL (HSP60 family)	524
2852597238	505	91.39	248	503	8	230	1.7e-46	155.3	COG2114	Adenylate cyclase, class 3	227
2852597240	504	91.39	240	502	8	230	1.7e-50	168.4	COG2114	Adenylate cyclase, class 3	227
2852597242	499	91.39	250	499	8	230	1.4e-49	164.4	COG2114	Adenylate cyclase, class 3	227
2852597245	453	49.2	301	430	128	250	3.2e-53	20.7	COG2966	Uncharacterized membrane protein YjjP, DUF1212 family	250
2852597245	453	96	23	277	11	250	3.2e-53	161.3	COG2966	Uncharacterized membrane protein YjjP, DUF1212 family	250
2852597246	153	94.16	10	149	3	131	1.9e-32	108.4	COG1765	Uncharacterized OsmC-related protein	137
2852597250	132	69.35	1	131	51	179	1.2e-23	80.2	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2852597253	513	94.04	18	229	8	212	6.7e-114	176.4	COG0516	IMP dehydrogenase/GMP reductase	170
2852597253	513	99.54	276	502	1	217	6.7e-114	203.1	COG0516	IMP dehydrogenase/GMP reductase	170
2852597254	378	13.3	210	301	43	71	1.3e-27	7.6	COG0516	IMP dehydrogenase/GMP reductase	170
2852597254	378	99.08	3	209	2	217	1.3e-27	86	COG0516	IMP dehydrogenase/GMP reductase	170
2852597255	577	98.06	1	551	5	561	6.9e-72	239.5	COG2303	Choline dehydrogenase or related flavoprotein	542
2852597256	55	31.43	2	49	29	50	8.3e-03	12.5	COG3311	Predicted DNA-binding transcriptional regulator AlpA	70
2852597257	142	25.77	11	137	151	225	2.4e-01	7.1	COG1426	Cytoskeletal protein RodZ, contains Xre-like HTH and DUF4115 domains	284
2852597258	219	90.2	1	219	10	230	1.9e-48	161.5	COG0704	Phosphate uptake regulator	240
2852597259	217	95.19	2	203	8	205	2.0e-45	151.2	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
2852597260	285	98.88	2	273	3	267	2.0e-56	187.9	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852597261	355	96.29	2	354	4	340	8.4e-77	254.8	COG3804	Uncharacterized protein	350
2852597262	193	91.87	2	193	11	202	2.7e-14	50.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852597265	519	97.98	6	196	3	196	5.6e-65	215.1	COG0518	GMP synthase - Glutamine amidotransferase domain	198
2852597265	519	99.68	197	519	2	316	0.0e+00	471	COG0519	GMP synthase, PP-ATPase domain/subunit	315
2852597266	256	98.31	3	251	2	234	3.8e-38	127.8	COG0412	Dienelactone hydrolase	236
2852597267	304	59.09	61	296	1	78	1.6e-15	53.1	COG0789	DNA-binding transcriptional regulator, MerR family	124
2852597268	496	97.09	1	446	8	440	5.7e-106	351.8	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
2852597269	305	11.8	144	185	50	70	1.2e-02	3.7	COG1633	Rubrerythrin	176
2852597269	305	18.54	7	94	131	163	1.2e-02	6.5	COG1633	Rubrerythrin	176
2852597270	276	77.61	9	241	5	212	8.0e-50	166.4	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852597271	325	93.4	6	318	18	314	3.3e-55	184.3	COG0657	Acetyl esterase/lipase	312
2852597274	512	13.9	1	67	22	73	2.9e-41	15.7	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
2852597274	512	98.4	56	476	5	372	2.9e-41	123.2	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
2852597275	148	98.5	16	141	2	132	6.0e-28	94	COG1846	DNA-binding transcriptional regulator, MarR family	126
2852597276	140	97.2	1	138	4	142	1.7e-45	151.3	COG1764	Organic hydroperoxide reductase OsmC/OhrA	143
2852597277	342	32.27	221	338	210	310	2.4e-95	75.8	COG1957	Inosine-uridine nucleoside N-ribohydrolase	311
2852597277	342	67.73	2	229	3	214	2.4e-95	238.7	COG1957	Inosine-uridine nucleoside N-ribohydrolase	311
2852597278	667	74.09	364	582	7	189	2.0e-26	87	COG3967	Short-chain dehydrogenase involved in D-alanine esterification of teichoic acids	245
2852597278	667	99.48	1	355	2	382	3.8e-76	253	COG3320	Thioester reductase domain of alpha aminoadipate reductase Lys2 and NRPSs	382
2852597279	289	39.62	55	145	93	155	1.3e-31	12.7	COG2030	Acyl dehydratase	159
2852597279	289	88.05	140	286	4	143	1.3e-31	91.9	COG2030	Acyl dehydratase	159
2852597280	295	86.16	147	288	21	157	1.5e-25	46	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2852597280	295	93.08	1	138	7	154	1.5e-25	46.9	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2852597281	234	19.17	154	220	182	227	5.6e-44	29.1	COG4312	Predicted dithiol-disulfide oxidoreductase, DUF899 family	247
2852597281	234	60.42	2	154	8	152	5.6e-44	116.5	COG4312	Predicted dithiol-disulfide oxidoreductase, DUF899 family	247
2852597282	1097	92.74	59	1097	3	1075	0.0e+00	1038	COG0587	DNA polymerase III, alpha subunit	1139
2852597283	138	57.24	1	102	5	87	1.6e-06	24	COG3871	General stress protein 26 (function unknown)	145
2852597284	213	97.22	4	213	7	216	4.4e-23	78.5	COG0778	Nitroreductase	207
2852597285	154	98.05	1	154	2	152	2.6e-56	186.3	COG0219	tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain	155
2852597286	201	54.84	3	200	26	178	1.1e-11	41.8	COG0500	SAM-dependent methyltransferase	257
2852597287	959	77.66	284	630	70	375	3.7e-15	53.3	COG0642	Signal transduction histidine kinase	336
2852597288	138	98.32	9	128	3	119	2.8e-32	107.7	COG2018	Predicted regulator of Ras-like GTPase activity, Roadblock/LC7/MglB family	119
2852597290	193	97.34	4	193	3	185	1.0e-57	191.3	COG2229	Signal recognition particle receptor subunit beta, a GTPase	187
2852597291	185	62.15	2	179	52	207	7.0e-31	103.6	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2852597293	192	97.13	1	192	4	206	4.5e-23	79.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852597295	424	96.05	2	374	11	302	2.8e-24	82.3	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
2852597296	304	100	1	303	1	331	1.2e-57	192.3	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2852597297	392	92.98	3	388	21	391	6.9e-19	61.9	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852597300	870	75.82	315	591	5	236	3.4e-72	239.7	COG1131	ABC-type multidrug transport system, ATPase component	293
2852597301	132	88.24	2	128	9	128	7.0e-10	35.2	COG3631	Ketosteroid isomerase-related protein	133
2852597302	187	75.6	4	186	17	174	4.9e-14	49.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852597304	397	97.52	2	388	4	357	5.2e-94	307.6	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
2852597305	283	98.24	4	283	1	279	2.7e-104	344.6	COG0190	5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase	283
2852597306	97	40.54	15	36	7	21	5.7e-01	7.7	COG4890	Predicted outer membrane lipoprotein	37
2852597306	97	59.46	39	62	9	30	5.7e-01	2.7	COG4890	Predicted outer membrane lipoprotein	37
2852597307	191	85.29	6	188	8	152	1.6e-08	30.7	COG0262	Dihydrofolate reductase	167
2852597308	213	86.1	7	183	2	162	8.2e-38	126.5	COG4185	Predicted ABC-type ATPase	187
2852597309	116	81.4	17	95	8	77	4.7e-06	22.5	COG2161	Antitoxin component YafN of the YafNO toxin-antitoxin module, PHD/YefM family	86
2852597311	200	79.43	8	199	18	183	3.6e-14	50.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852597312	525	96.95	4	400	3	383	4.1e-61	204.1	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2852597314	165	80.83	1	118	10	106	2.5e-32	107.4	COG1733	DNA-binding transcriptional regulator, HxlR family	120
2852597315	243	55.91	5	224	43	198	4.0e-20	69.2	COG0500	SAM-dependent methyltransferase	257
2852597316	373	97.85	1	371	8	371	3.4e-130	430.9	COG2021	Homoserine acetyltransferase	368
2852597317	447	99.06	5	430	4	426	0.0e+00	680.9	COG2873	O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent	426
2852597319	751	99.73	1	745	1	742	0.0e+00	1356.5	COG2838	Monomeric isocitrate dehydrogenase	744
2852597320	277	91.86	2	266	22	292	1.6e-27	93.3	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852597321	263	98.46	1	263	3	257	2.3e-73	243.2	COG0708	Exonuclease III	261
2852597322	443	99.02	1	416	2	407	0.0e+00	453	COG1252	NADH dehydrogenase, FAD-containing subunit	405
2852597323	337	98.74	1	314	4	316	7.8e-108	357	COG0180	Tryptophanyl-tRNA synthetase	314
2852597324	343	93.4	8	316	7	289	6.0e-61	202.5	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
2852597325	407	79.9	9	391	12	325	1.7e-81	270.8	COG1686	D-alanyl-D-alanine carboxypeptidase	389
2852597326	335	5.83	30	57	111	128	8.0e-32	6.2	COG3386	Sugar lactone lactonase YvrE	307
2852597326	335	68.28	37	264	31	241	8.0e-32	104.6	COG3386	Sugar lactone lactonase YvrE	307
2852597327	461	97.76	10	461	7	443	0.0e+00	469.3	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
2852597328	173	93.67	24	170	5	152	3.9e-26	88.3	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2852597329	501	98.75	13	487	3	475	0.0e+00	565	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2852597330	225	75.12	5	224	12	168	2.2e-18	64.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852597331	283	93.99	2	282	10	275	2.1e-39	132	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2852597332	261	91.67	1	234	18	226	5.9e-73	241.8	COG0765	ABC-type amino acid transport system, permease component	222
2852597333	258	98.35	10	258	3	240	7.6e-102	336	COG1126	ABC-type polar amino acid transport system, ATPase component	240
2852597334	530	96.7	2	522	18	544	1.3e-111	370.5	COG0405	Gamma-glutamyltranspeptidase	539
2852597335	301	83.87	3	171	20	175	6.7e-34	113.2	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2852597336	203	97.31	10	182	4	184	3.1e-31	105.4	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
2852597337	258	97.45	21	258	2	230	1.6e-86	285.7	COG0479	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit	234
2852597338	584	99.29	1	575	5	566	0.0e+00	755	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
2852597339	160	87.18	40	156	15	116	1.5e-32	108.3	COG2142	Succinate dehydrogenase, hydrophobic anchor subunit	117
2852597340	142	92.48	18	137	11	133	1.2e-28	96.3	COG2009	Succinate dehydrogenase/fumarate reductase, cytochrome b subunit	132
2852597341	141	94.16	2	131	8	136	7.7e-35	116.3	COG0295	Cytidine deaminase	134
2852597342	162	90.62	1	149	8	152	5.6e-26	87.9	COG4244	Uncharacterized membrane protein	160
2852597343	433	99.31	5	432	3	435	0.0e+00	496.8	COG0213	Thymidine phosphorylase	435
2852597344	362	96.82	5	360	8	342	1.6e-104	346.2	COG1816	Adenosine deaminase	345
2852597345	237	86.1	1	237	40	293	9.3e-19	64.8	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852597346	114	81.51	5	109	5	123	8.5e-05	17	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2852597347	333	100	1	332	1	331	5.0e-91	302	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2852597348	230	83.96	2	226	2	226	2.8e-43	144.9	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852597349	303	98.98	31	301	3	294	1.1e-41	139.8	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852597350	190	91.39	4	189	5	195	3.1e-21	73.3	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852597351	279	93.28	1	257	6	255	4.4e-47	157.4	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852597353	189	94.26	1	188	5	201	1.2e-21	74.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852597354	191	90.43	1	185	13	201	2.7e-16	57.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852597355	502	98.96	7	494	5	480	2.6e-116	385.8	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
2852597356	311	84.33	7	277	2	227	7.1e-48	159.9	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852597357	235	76.56	1	226	15	174	7.9e-16	55.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852597359	197	60.75	1	165	99	259	2.9e-40	134.7	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2852597360	303	59.49	5	182	4	144	3.5e-19	58.7	COG0412	Dienelactone hydrolase	236
2852597361	488	96.13	1	487	12	557	2.7e-118	391.2	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2852597362	414	92.29	1	352	3	337	1.6e-99	330	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
2852597363	276	91.04	3	272	2	245	8.0e-45	150	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852597365	409	95.71	1	409	12	413	1.4e-62	208.3	COG1914	Mn2+ and Fe2+ transporters of the NRAMP family	416
2852597369	200	97.13	1	197	2	204	9.4e-17	58.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852597370	363	74.07	88	162	11	70	1.0e-02	11.4	COG1722	Exonuclease VII small subunit	81
2852597372	207	99.05	1	207	2	209	9.0e-77	254	COG0035	Uracil phosphoribosyltransferase	210
2852597373	551	96.03	31	550	6	464	4.4e-122	404.6	COG1109	Phosphomannomutase	464
2852597374	150	75.94	12	138	6	106	1.1e-18	63.7	COG1846	DNA-binding transcriptional regulator, MarR family	126
2852597375	358	93.47	1	338	18	346	4.6e-62	206.3	COG3180	Uncharacterized membrane protein AbrB, regulator of aidB expression	352
2852597376	264	98.86	7	264	3	262	5.8e-75	248.8	COG0005	Purine nucleoside phosphorylase	262
2852597377	393	93.89	8	381	4	372	6.6e-77	255.5	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
2852597378	389	97.2	1	389	8	389	5.3e-106	351.6	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
2852597381	471	99.12	1	461	5	455	6.0e-124	410.8	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
2852597382	579	99.07	18	547	1	532	0.0e+00	585.4	COG0578	Glycerol-3-phosphate dehydrogenase	532
2852597383	296	83.56	15	282	44	287	2.6e-48	161.4	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
2852597386	127	75	26	119	16	87	1.6e-05	21.4	COG5470	Uncharacterized conserved protein, DUF1330 family	96
2852597387	299	84.06	2	281	7	238	9.4e-39	129.9	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
2852597388	256	98.88	10	254	2	266	3.2e-63	210.4	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852597389	259	94.72	2	259	11	261	1.3e-67	224.4	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2852597390	227	74.64	17	219	10	165	9.6e-21	71.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852597391	355	98.13	40	297	6	268	1.9e-51	171.3	COG1018	Ferredoxin-NADP reductase	266
2852597392	369	91.64	20	368	6	323	4.3e-55	183.2	COG3239	Fatty acid desaturase	343
2852597393	253	100	1	253	1	274	6.2e-57	189.7	COG0266	Formamidopyrimidine-DNA glycosylase	273
2852597394	316	82.84	23	303	2	223	3.6e-43	144.6	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852597395	326	98.55	1	319	1	340	1.2e-56	188.7	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
2852597396	1508	98.61	2	889	5	857	0.0e+00	948.3	COG1201	Lhr-like helicase	814
2852597397	216	94.26	1	202	5	201	1.3e-24	84.5	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852597398	394	95.25	9	393	23	463	2.1e-87	287.5	COG1690	RNA-splicing ligase RtcB, repairs tRNA damage	432
2852597399	789	99.61	2	762	2	771	0.0e+00	791.4	COG1554	Trehalose and maltose hydrolase (possible phosphorylase)	772
2852597400	247	95.93	7	246	2	213	6.8e-50	165.9	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
2852597402	514	96.24	25	504	17	477	0.0e+00	491.3	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2852597403	400	20.26	301	400	349	441	2.0e-127	61.3	COG5383	Uncharacterized metalloenzyme YdcJ, glyoxalase superfamily	295
2852597403	400	68.19	1	312	3	315	2.0e-127	359	COG5383	Uncharacterized metalloenzyme YdcJ, glyoxalase superfamily	295
2852597404	153	89.87	4	151	4	145	4.5e-28	94.6	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2852597405	444	93.5	8	444	28	444	7.4e-108	357.5	COG0160	4-aminobutyrate aminotransferase or related aminotransferase	447
2852597406	178	53.46	45	173	97	212	1.1e-23	80.1	COG1787	Endonuclease, HJR/Mrr/RecB family	217
2852597407	226	67.96	65	159	17	86	4.1e-04	16.4	COG3925	N-terminal domain of the phosphotransferase system fructose-specific component IIB	103
2852597408	125	25.74	7	58	10	35	6.3e-02	6.3	COG4327	Uncharacterized membrane protein	101
2852597408	125	32.67	78	123	13	45	6.3e-02	4.3	COG4327	Uncharacterized membrane protein	101
2852597409	102	15.37	1	90	222	302	1.6e-02	10.1	COG1955	Archaellum biogenesis protein FlaJ, TadC family	527
2852597410	81	76.12	1	75	7	57	1.3e-09	34.4	COG3237	Uncharacterized conserved protein YjbJ, UPF0337 family	67
2852597411	113	35.23	1	97	6	36	9.5e-04	13.9	COG1873	Sporulation protein YlmC, PRC-barrel domain family	87
2852597413	409	92.62	10	406	24	412	6.1e-41	136.8	COG1914	Mn2+ and Fe2+ transporters of the NRAMP family	416
2852597415	281	98.13	32	278	3	265	7.0e-65	215.8	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852597417	398	94.13	32	387	20	404	5.3e-41	137.8	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2852597418	338	83.99	2	336	25	323	4.8e-69	229.5	COG3569	DNA topoisomerase IB	354
2852597419	144	90.41	2	142	14	145	3.0e-08	29.7	COG2172	Anti-sigma regulatory factor (Ser/Thr protein kinase)	146
2852597420	241	90.48	3	241	23	250	1.3e-74	247.5	COG1191	DNA-directed RNA polymerase specialized sigma subunit	247
2852597421	146	77.78	23	134	15	105	1.1e-11	40.5	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
2852597422	180	91.5	2	180	5	187	1.3e-31	106.6	COG2068	CTP:molybdopterin cytidylyltransferase MocA	199
2852597424	231	85.14	1	231	1	235	1.4e-36	122.8	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
2852597425	599	14.4	468	599	553	645	0.0e+00	90.4	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
2852597425	599	69.66	8	473	2	451	0.0e+00	747.5	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
2852597426	228	80.53	42	224	36	188	3.2e-34	114.7	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
2852597427	141	93.75	1	140	7	141	7.9e-37	122.6	COG2166	Sulfur transfer protein SufE, Fe-S center assembly	144
2852597428	295	98.61	9	290	4	286	1.2e-92	306.6	COG2897	3-mercaptopyruvate sulfurtransferase SseA, contains two rhodanese domains	285
2852597429	448	91.97	3	429	11	411	7.5e-89	294.6	COG0677	UDP-N-acetyl-D-mannosaminuronate dehydrogenase	436
2852597430	326	98.75	1	319	3	319	3.0e-67	224	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2852597434	374	42.56	35	226	50	152	3.3e-06	18	COG2202	PAS domain	232
2852597434	374	80	298	374	13	76	7.5e-17	56.5	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2852597435	214	98.97	1	205	2	193	1.8e-54	180.5	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
2852597437	546	99.62	12	546	3	526	0.0e+00	755.8	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component	526
2852597438	266	45.88	5	244	60	187	2.4e-05	21.3	COG0500	SAM-dependent methyltransferase	257
2852597439	379	96.09	14	379	14	406	1.2e-24	84.2	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2852597440	329	9.59	6	42	3	35	2.1e-93	34.8	COG1089	GDP-D-mannose dehydratase	345
2852597440	329	81.4	39	309	63	342	2.1e-93	273.3	COG1089	GDP-D-mannose dehydratase	345
2852597441	227	73.68	44	222	47	186	9.9e-22	72	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
2852597442	371	91.2	8	369	33	405	7.6e-07	25.7	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2852597444	390	7.88	6	98	22	59	4.2e-03	3.5	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
2852597444	390	53.32	117	375	154	410	4.2e-03	12.1	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
2852597445	376	39.12	54	375	233	392	6.3e-05	19.5	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2852597449	520	73.08	210	478	32	240	7.9e-38	126.8	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
2852597450	414	72.88	135	382	48	262	4.5e-06	23.5	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852597451	222	81.86	6	209	8	192	1.8e-12	43.4	COG3944	Capsular polysaccharide biosynthesis protein	226
2852597452	425	71.7	28	393	38	265	7.5e-07	25	COG0657	Acetyl esterase/lipase	312
2852597453	436	92.54	26	436	8	367	9.2e-47	155.2	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
2852597456	209	17.32	102	187	139	178	8.6e-11	28.8	COG1434	Uncharacterized SAM-binding protein YcdF, DUF218 family	223
2852597456	209	22.94	1	84	25	77	8.6e-11	8.5	COG1434	Uncharacterized SAM-binding protein YcdF, DUF218 family	223
2852597457	460	50.93	282	447	159	323	4.1e-30	47.6	COG0627	S-formylglutathione hydrolase FrmB	316
2852597457	460	53.4	40	288	23	195	4.1e-30	52.7	COG0627	S-formylglutathione hydrolase FrmB	316
2852597458	496	86.67	272	496	31	225	1.0e-73	243.4	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
2852597459	266	98.33	32	266	2	236	2.2e-63	210.7	COG0340	Biotin-(acetyl-CoA carboxylase) ligase	238
2852597460	412	81.02	87	403	44	282	2.4e-08	30.6	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852597461	172	21.82	14	152	14	121	6.8e-14	47.9	COG3428	Uncharacterized membrane protein YdbT, contains bPH2 (bacterial pleckstrin homology) domain	494
2852597462	218	93.53	15	154	7	136	5.6e-33	110.5	COG2246	Putative flippase GtrA (transmembrane translocase of bactoprenol-linked glucose)	139
2852597463	396	93.35	1	389	4	354	5.9e-122	403.7	COG0026	Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	375
2852597464	167	96.95	1	163	4	162	4.6e-74	243.9	COG0041	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase	162
2852597466	387	98.25	7	387	3	394	0.0e+00	455.8	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852597468	489	97.01	2	363	11	334	7.7e-86	284.8	COG1316	Anionic cell wall polymer biosynthesis enzyme,  LytR-Cps2A-Psr (LCP) family	307
2852597469	286	98.58	7	286	2	279	4.2e-93	307.9	COG1091	dTDP-4-dehydrorhamnose reductase	281
2852597470	554	97.01	1	553	8	558	4.7e-99	329.2	COG2303	Choline dehydrogenase or related flavoprotein	542
2852597471	291	91.37	2	291	5	290	3.4e-71	236.4	COG1216	Glycosyltransferase, GT2 family	305
2852597472	353	99.21	1	349	3	377	6.0e-102	337.9	COG1208	NDP-sugar pyrophosphorylase, includes eIF-2Bgamma, eIF-2Bepsilon, and LPS biosynthesis proteins	358
2852597473	183	74.42	10	177	15	142	2.2e-08	30.7	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2852597474	446	90.28	254	442	12	206	7.9e-20	67.2	COG0778	Nitroreductase	207
2852597474	446	98.05	8	251	3	254	1.8e-85	282.5	COG1478	F420-0:Gamma-glutamyl ligase (F420 biosynthesis)	257
2852597475	331	93.15	1	329	8	306	1.5e-87	290.1	COG0391	Archaeal 2-phospho-L-lactate transferase/Bacterial gluconeogenesis factor, CofD/UPF0052 family	323
2852597477	154	82.35	26	153	14	125	7.1e-03	11.1	COG3824	Predicted Zn-dependent protease, minimal metalloprotease (MMP)-like domain	136
2852597479	461	94.77	5	459	14	466	7.8e-117	387.3	COG1109	Phosphomannomutase	464
2852597481	408	98.38	1	405	5	368	6.0e-112	370.7	COG1482	Mannose-6-phosphate isomerase, class I	312
2852597482	314	98.35	1	308	1	298	3.0e-119	394.1	COG2354	Uncharacterized membrane protein MutK, may be involved in DNA repair	303
2852597484	638	97.49	38	440	7	395	1.2e-100	334.1	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852597485	456	89.06	6	416	5	354	2.4e-13	43.2	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2852597486	494	97.97	18	493	4	485	1.2e-98	327.3	COG0531	Amino acid transporter	466
2852597488	62	98.18	1	56	1	54	3.8e-22	74.6	COG1773	Rubredoxin	55
2852597489	60	92.73	4	58	3	53	9.9e-26	86	COG1773	Rubredoxin	55
2852597490	210	77.03	8	205	14	174	1.3e-16	58.3	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852597491	485	99.52	10	477	3	419	0.0e+00	648.4	COG0499	S-adenosylhomocysteine hydrolase	420
2852597492	183	89.78	5	180	14	180	1.4e-53	177.7	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2852597493	392	74.18	164	355	51	231	3.9e-24	82.1	COG2114	Adenylate cyclase, class 3	227
2852597495	209	92.79	1	209	5	197	4.6e-40	134.1	COG0125	Thymidylate kinase	208
2852597496	225	98.28	3	225	2	229	8.0e-85	280.3	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2852597497	522	82.49	111	493	66	390	2.0e-72	241.6	COG0642	Signal transduction histidine kinase	336
2852597501	150	47.78	20	150	82	167	4.0e-19	62	COG0723	Rieske Fe-S protein	177
2852597502	209	91.52	1	209	18	222	5.3e-39	130.6	COG1040	Predicted amidophosphoribosyltransferases	225
2852597503	227	91.82	26	140	2	102	3.4e-30	100.7	COG1544	Ribosome-associated translation inhibitor RaiA	110
2852597504	940	96.43	1	896	5	814	0.0e+00	1243.1	COG0653	Preprotein translocase subunit SecA (ATPase, RNA helicase)	822
2852597505	156	96.82	1	155	6	157	1.5e-07	28	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
2852597509	413	99.25	91	356	1	266	2.4e-67	223.5	COG1018	Ferredoxin-NADP reductase	266
2852597510	409	98.56	8	380	4	345	5.1e-92	305	COG3239	Fatty acid desaturase	343
2852597511	214	53.76	3	212	45	194	1.4e-19	67.5	COG0500	SAM-dependent methyltransferase	257
2852597512	282	97.52	3	279	6	280	3.9e-102	337.3	COG0656	Aldo/keto reductase, related to diketogulonate reductase	280
2852597514	329	97.68	29	329	2	296	2.0e-71	237.1	COG1162	Putative ribosome biogenesis GTPase RsgA	301
2852597515	433	98.84	1	424	4	428	1.1e-119	396.3	COG0128	5-enolpyruvylshikimate-3-phosphate synthase	428
2852597516	259	99.56	1	252	1	225	9.1e-72	237.5	COG2135	Putative SOS response-associated peptidase YedK	226
2852597517	199	90.43	1	194	11	199	2.9e-14	50.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852597518	274	94.72	16	274	5	255	8.7e-63	208.5	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2852597520	288	85.33	13	288	45	300	1.2e-71	238	COG3662	Uncharacterized conserved protein, DUF2236 family	300
2852597522	515	96.24	2	472	14	474	0.0e+00	448.8	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2852597523	387	100	1	386	1	366	1.6e-106	349.4	COG1062	Zn-dependent alcohol dehydrogenase	366
2852597524	282	91.04	1	248	1	244	8.8e-43	143.3	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852597525	166	98.06	5	166	2	153	1.1e-47	157.8	COG2606	Cys-tRNA(Pro) deacylase, prolyl-tRNA editing enzyme YbaK/EbsC	155
2852597526	265	93.01	63	250	8	180	3.0e-54	179.8	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2852597527	101	13.69	22	99	12	44	3.8e-04	16.4	COG5660	Predicted anti-sigma-YlaC factor YlaD, contains Zn-finger domain	238
2852597529	79	48.98	1	79	75	146	2.7e-22	76.8	COG0511	Biotin carboxyl carrier protein	140
2852597530	498	98.25	271	495	2	225	4.0e-54	179.2	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
2852597532	321	98.01	1	318	4	299	1.5e-59	197.9	COG1597	Diacylglycerol kinase family enzyme	301
2852597533	141	27.51	1	132	182	288	2.7e-02	9.9	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
2852597534	159	81.48	10	148	28	159	3.7e-12	43.3	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2852597535	368	79.06	12	365	89	424	1.2e-109	363.8	COG1169	Isochorismate synthase EntC	423
2852597536	203	93.3	4	199	4	198	6.4e-45	149.9	COG0406	Broad specificity phosphatase PhoE	208
2852597537	267	98.11	5	259	3	261	6.6e-73	242.2	COG1192	Cellulose biosynthesis protein BcsQ	259
2852597538	245	91.42	3	244	5	249	4.5e-46	153.9	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852597539	315	73.46	47	313	30	220	9.3e-19	64.2	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2852597540	136	92.42	6	117	2	123	4.9e-20	68.4	COG0789	DNA-binding transcriptional regulator, MerR family	124
2852597542	486	87.12	1	485	28	480	0.0e+00	494.2	COG0513	Superfamily II DNA and RNA helicase	513
2852597543	230	47.78	35	181	63	159	1.5e-08	30.9	COG4445	tRNA isopentenyl-2-thiomethyl-A-37 hydroxylase MiaE (synthesis of 2-methylthio-cis-ribozeatin)	203
2852597546	266	91.87	63	264	11	202	5.6e-28	95.2	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852597548	392	92.98	284	392	6	111	4.2e-20	67.3	COG0607	Rhodanese-related sulfurtransferase	110
2852597548	392	95.79	13	265	2	251	3.7e-91	301.1	COG0476	Molybdopterin or thiamine biosynthesis adenylyltransferase	254
2852597550	98	97.09	2	98	2	101	9.7e-32	105.8	COG3695	Alkylated DNA nucleotide flippase Atl1, participates in nucleotide excision repair, Ada-like DNA-binding domain	103
2852597551	258	94.92	1	258	11	290	3.9e-28	95.6	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852597552	1037	96.13	6	715	14	658	1.0e-59	199.1	COG0210	Superfamily I DNA or RNA helicase	655
2852597552	1037	96.28	793	1032	1	259	5.7e-41	135.7	COG2887	RecB family exonuclease	269
2852597553	1074	76.95	853	1071	46	252	1.5e-19	67.3	COG2887	RecB family exonuclease	269
2852597553	1074	97.02	18	790	4	654	2.7e-122	405.9	COG0210	Superfamily I DNA or RNA helicase	655
2852597554	134	84.73	12	134	14	124	1.7e-20	70.1	COG4270	Uncharacterized membrane protein	131
2852597555	367	34.98	22	141	91	168	5.3e-31	4.9	COG1226	Voltage-gated potassium channel Kch	212
2852597555	367	78.92	133	337	15	190	5.3e-31	103.7	COG1226	Voltage-gated potassium channel Kch	212
2852597556	310	99.3	19	308	2	283	1.8e-77	257.3	COG2816	NADH pyrophosphatase NudC, Nudix superfamily	279
2852597557	922	75	842	916	11	70	2.1e-15	51.1	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2852597558	82	90	2	79	3	74	3.6e-13	46.1	COG0695	Glutaredoxin	80
2852597559	701	13.41	478	586	563	652	0.0e+00	75.5	COG0210	Superfamily I DNA or RNA helicase	655
2852597559	701	71.54	14	491	3	482	0.0e+00	405.9	COG0210	Superfamily I DNA or RNA helicase	655
2852597562	441	86.52	1	441	9	451	3.9e-105	349.1	COG0661	Predicted unusual protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family	517
2852597564	451	100	45	422	1	359	0.0e+00	517.3	COG5282	Uncharacterized conserved protein, DUF2342 family	359
2852597565	340	96.49	2	340	1	330	2.1e-112	372.1	COG3480	Predicted secreted protein containing a PDZ domain	342
2852597566	1001	99.89	12	999	1	907	0.0e+00	1287.9	COG1615	Uncharacterized membrane protein, UPF0182 family	885
2852597567	603	96.31	1	588	17	617	2.0e-124	412.8	COG3387	Glucoamylase (glucan-1,4-alpha-glucosidase), GH15 family	612
2852597568	352	99.72	1	348	1	352	4.0e-43	143.8	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
2852597569	155	84.21	12	145	18	129	1.1e-21	73.6	COG1846	DNA-binding transcriptional regulator, MarR family	126
2852597570	315	77.27	192	313	18	119	2.6e-19	65.1	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2852597573	83	26.87	12	82	196	267	8.3e-06	22.1	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852597574	395	91.45	3	394	32	416	9.6e-92	304.3	COG2124	Cytochrome P450	411
2852597575	256	97.39	5	251	3	263	3.6e-63	210.1	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852597576	247	98.13	1	246	4	266	1.9e-64	214.3	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852597577	278	76.12	1	238	10	213	1.6e-33	112.9	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852597578	256	98.51	4	254	3	266	1.3e-55	185.4	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852597579	215	73.21	1	205	6	158	7.1e-17	59.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852597584	138	43.08	3	119	17	72	6.7e-08	30.1	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2852597586	304	76.92	25	302	19	218	1.6e-26	89.9	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2852597587	149	22.12	4	148	79	174	1.8e-03	14	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
2852597589	965	98.09	6	948	6	929	0.0e+00	1052.4	COG2409	Uncharacterized membrane protein YdfJ, MMPL/SSD domain	937
2852597591	207	81.82	5	204	4	174	3.0e-17	60.3	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852597592	537	96.64	5	537	17	562	1.5e-129	429.8	COG2936	Predicted acyl esterase	563
2852597593	287	10.15	3	52	44	77	3.4e-18	8.4	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2852597593	287	51.04	84	274	126	296	3.4e-18	52.6	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2852597594	247	98.51	1	246	4	267	2.6e-58	194.2	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852597595	325	93.62	9	308	6	269	2.1e-83	275.8	COG0656	Aldo/keto reductase, related to diketogulonate reductase	280
2852597596	238	96.12	19	231	1	198	5.3e-19	65.1	COG1335	Nicotinamidase-related amidase	205
2852597597	196	89.95	1	196	9	196	2.3e-25	87.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852597598	230	92.35	16	230	10	190	3.5e-34	114.7	COG0693	Putative intracellular protease/amidase	188
2852597599	279	96.98	2	260	7	263	4.2e-45	150.5	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2852597600	321	98.64	39	319	4	294	3.2e-35	118.7	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852597601	97	90.91	1	95	3	92	1.8e-11	40.3	COG1359	Quinol monooxygenase YgiN	100
2852597602	763	98.89	9	755	9	809	8.6e-115	379.5	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2852597603	474	99.57	1	471	3	470	0.0e+00	653.8	COG1282	NAD/NADP transhydrogenase beta subunit	463
2852597604	99	29.48	1	99	98	204	7.3e-23	78.1	COG3288	NAD/NADP transhydrogenase alpha subunit	356
2852597605	359	99.45	3	358	2	362	0.0e+00	472.8	COG3288	NAD/NADP transhydrogenase alpha subunit	356
2852597606	335	96.44	1	321	2	299	4.6e-71	235.9	COG1893	Ketopantoate reductase	307
2852597607	473	99.16	1	472	4	477	0.0e+00	543	COG0469	Pyruvate kinase	477
2852597608	153	49.59	6	136	123	242	4.1e-14	49.2	COG2202	PAS domain	232
2852597609	317	95.35	8	300	3	289	8.6e-55	183.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2852597610	580	96.4	23	574	3	537	0.0e+00	453	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
2852597611	418	98.5	1	417	7	401	3.8e-129	427.6	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2852597612	152	88.55	2	152	18	164	2.0e-46	153.8	COG1905	NADH:ubiquinone oxidoreductase 24 kD subunit (chain E)	160
2852597613	523	98.11	96	517	4	419	0.0e+00	544	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
2852597614	806	21.88	15	237	5	218	0.0e+00	270.4	COG3383	Predicted molibdopterin-dependent oxidoreductase YjgC	978
2852597614	806	52.56	235	773	262	775	0.0e+00	753.8	COG3383	Predicted molibdopterin-dependent oxidoreductase YjgC	978
2852597615	148	12.99	1	138	811	937	2.0e-40	135	COG3383	Predicted molibdopterin-dependent oxidoreductase YjgC	978
2852597619	445	49.09	253	444	6	193	1.8e-17	43.6	COG0477	MFS family permease	338
2852597619	445	62.66	31	273	8	247	1.8e-17	19.1	COG0477	MFS family permease	338
2852597620	280	99.25	1	274	2	266	1.7e-89	296.1	COG1526	Formate dehydrogenase assembly factor FdhD	266
2852597621	239	93.97	13	238	7	224	8.0e-56	185.5	COG1802	DNA-binding transcriptional regulator, GntR family	230
2852597622	463	49.09	30	251	11	198	2.5e-21	21.4	COG0477	MFS family permease	338
2852597622	463	54.05	256	461	5	211	2.5e-21	57.4	COG0477	MFS family permease	338
2852597623	408	98.25	2	408	8	401	2.3e-116	385.4	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2852597624	427	99	14	427	5	401	3.0e-121	401.5	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2852597625	461	51.96	254	456	8	206	3.2e-22	47.3	COG0477	MFS family permease	338
2852597625	461	63.19	29	281	9	250	3.2e-22	30.3	COG0477	MFS family permease	338
2852597626	240	93.97	15	240	12	229	2.8e-53	177.2	COG1802	DNA-binding transcriptional regulator, GntR family	230
2852597627	249	98.78	6	246	1	243	1.1e-69	230.6	COG1414	DNA-binding transcriptional regulator, IclR family	246
2852597628	598	99.66	1	597	1	590	0.0e+00	1114.5	COG3960	Glyoxylate carboligase	592
2852597629	295	98.25	2	286	2	282	1.0e-100	333.1	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
2852597630	276	94.23	1	265	1	245	3.3e-52	174.1	COG3622	Hydroxypyruvate isomerase	260
2852597631	379	98.15	3	374	2	372	2.6e-105	348.8	COG1929	Glycerate kinase	378
2852597632	324	99.7	1	323	1	330	2.0e-79	263.9	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2852597633	320	97.29	27	314	7	293	1.4e-41	139.5	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852597634	461	98.24	11	461	6	451	4.3e-123	408.1	COG1231	Monoamine oxidase	450
2852597635	329	86.01	4	326	19	313	7.8e-36	120.2	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852597636	493	98.43	2	450	8	446	5.0e-130	431.1	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
2852597637	505	97.98	2	448	7	443	4.0e-128	424.9	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
2852597638	253	76.52	112	247	21	121	2.5e-17	59	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2852597642	376	97.86	15	372	4	323	5.6e-83	275.3	COG3173	Predicted  kinase, aminoglycoside phosphotransferase (APT) family	321
2852597643	203	84.21	3	200	7	182	1.4e-17	61.5	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852597644	226	62.2	5	219	9	161	7.3e-29	97.5	COG2120	N-acetylglucosaminyl deacetylase, LmbE family	237
2852597645	263	99.25	2	253	2	267	1.1e-64	215.1	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852597646	259	93.21	1	253	7	253	7.6e-65	215.4	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2852597647	524	17.44	7	114	6	88	0.0e+00	12.6	COG1007	NADH:ubiquinone oxidoreductase subunit 2 (chain N)	475
2852597647	524	82.35	117	523	82	473	0.0e+00	447.3	COG1007	NADH:ubiquinone oxidoreductase subunit 2 (chain N)	475
2852597648	522	98.8	3	518	2	493	0.0e+00	576.6	COG1008	NADH:ubiquinone oxidoreductase subunit 4 (chain M)	497
2852597649	636	99.84	5	629	1	616	0.0e+00	644	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
2852597650	99	94	1	99	6	99	1.1e-37	124.6	COG0713	NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K)	100
2852597651	256	98.81	18	185	3	168	3.1e-41	137.2	COG0839	NADH:ubiquinone oxidoreductase subunit 6 (chain J)	166
2852597652	174	85.71	2	172	14	163	6.6e-50	165.5	COG1143	Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)	172
2852597653	413	96.1	7	348	10	329	2.8e-123	407.3	COG1005	NADH:ubiquinone oxidoreductase subunit 1 (chain H)	332
2852597654	795	99.73	15	750	1	729	0.0e+00	605.2	COG1034	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)	693
2852597655	438	96.46	1	421	13	421	0.0e+00	613.3	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
2852597656	289	93.98	18	182	9	164	1.0e-56	185.9	COG1905	NADH:ubiquinone oxidoreductase 24 kD subunit (chain E)	160
2852597657	439	98.49	24	439	7	398	0.0e+00	545	COG0649	NADH:ubiquinone oxidoreductase 49 kD subunit (chain D)	398
2852597658	230	76.67	58	225	20	157	3.2e-51	170.3	COG0852	NADH:ubiquinone oxidoreductase 27 kD subunit (chain C)	176
2852597659	184	77.84	2	179	17	167	4.2e-75	247.5	COG0377	NADH:ubiquinone oxidoreductase 20 kD subunit (chhain B) or related Fe-S oxidoreductase	194
2852597660	123	95.9	1	123	5	121	1.1e-42	141.4	COG0838	NADH:ubiquinone oxidoreductase subunit 3 (chain A)	123
2852597661	131	49.57	6	129	2	116	2.7e-08	29.6	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2852597662	177	84.97	1	174	16	179	4.1e-32	107.8	COG2353	Polyisoprenoid-binding periplasmic protein YceI	192
2852597663	129	86.03	3	122	11	127	5.8e-07	22.7	COG3631	Ketosteroid isomerase-related protein	133
2852597664	209	53.41	3	207	46	194	2.0e-16	57.3	COG0500	SAM-dependent methyltransferase	257
2852597666	143	84.21	12	139	16	127	2.5e-21	72.5	COG1846	DNA-binding transcriptional regulator, MarR family	126
2852597668	315	91.13	3	303	25	322	4.1e-45	150.6	COG3173	Predicted  kinase, aminoglycoside phosphotransferase (APT) family	321
2852597669	412	95.99	2	411	12	394	2.7e-98	326	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852597670	203	79.43	3	199	9	174	3.6e-26	89.5	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852597671	302	69.01	6	300	2	286	3.7e-51	170.9	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
2852597672	401	98.25	1	401	7	400	4.4e-127	420.9	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2852597673	399	86.44	11	373	21	275	3.1e-10	34.8	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852597674	367	65.57	59	366	122	401	1.8e-35	118.9	COG3508	Homogentisate 1,2-dioxygenase	427
2852597676	188	88.04	1	188	14	197	7.4e-12	43.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852597677	324	93.52	8	324	17	319	6.2e-89	294.9	COG0627	S-formylglutathione hydrolase FrmB	316
2852597678	332	98.19	4	329	3	327	1.1e-57	192.4	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2852597679	404	98.75	3	402	3	396	8.2e-81	268.6	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852597680	458	94.74	87	458	3	380	1.6e-81	270.8	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852597681	262	99.23	4	260	2	258	4.0e-68	226	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
2852597683	454	98.25	1	453	5	454	8.2e-69	228.6	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
2852597684	371	99.58	129	366	1	238	1.4e-100	331.7	COG1186	Protein chain release factor B	239
2852597685	318	78.36	3	303	47	314	2.2e-44	148.4	COG0668	Small-conductance mechanosensitive channel	316
2852597687	230	99.55	2	225	1	222	4.9e-101	333.6	COG2884	ABC-type ATPase involved in cell division	223
2852597688	297	98.32	1	297	5	296	2.7e-83	275.9	COG2177	Cell division protein FtsX	297
2852597689	164	96.73	7	161	4	151	1.2e-65	216.3	COG0691	tmRNA-binding protein	153
2852597690	273	93.02	1	273	15	294	5.3e-16	51.4	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2852597692	172	93.94	10	143	8	131	3.4e-33	110.4	COG2343	Uncharacterized conserved protein, DUF427 family	132
2852597696	130	43.39	3	130	2	129	5.3e-16	55.9	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852597697	362	77.87	96	307	46	235	1.5e-29	99.1	COG2114	Adenylate cyclase, class 3	227
2852597700	323	90.17	67	282	9	274	6.6e-17	53.5	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852597702	281	98.13	6	278	4	266	1.1e-63	211.8	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852597704	246	94.92	6	244	4	227	3.1e-45	151.1	COG5522	Uncharacterized membrane protein YwaF	236
2852597705	593	66.17	7	403	2	312	1.1e-58	195.6	COG0515	Serine/threonine protein kinase	384
2852597706	551	66.28	33	468	101	446	2.1e-15	50.4	COG3540	Phosphodiesterase/alkaline phosphatase D	522
2852597707	309	91.72	19	309	21	297	3.1e-58	193.6	COG1597	Diacylglycerol kinase family enzyme	301
2852597708	338	92.41	19	323	9	288	1.7e-37	125.6	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
2852597709	241	58.62	6	231	78	213	3.0e-23	79.1	COG0671	Membrane-associated phospholipid phosphatase	232
2852597710	252	73.71	4	236	42	212	6.5e-19	65	COG0671	Membrane-associated phospholipid phosphatase	232
2852597712	287	88.5	2	287	7	283	6.4e-81	268.1	COG3509	Poly(3-hydroxybutyrate) depolymerase	312
2852597713	117	93.84	4	113	7	143	1.2e-09	34.2	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2852597714	292	98.31	7	287	5	294	7.9e-32	107.6	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852597716	397	98.22	5	396	2	388	1.5e-29	97.3	COG0183	Acetyl-CoA acetyltransferase	392
2852597717	147	85.11	14	144	17	136	6.9e-24	80.3	COG1545	Uncharacterized OB-fold protein, contains Zn-ribbon domain	140
2852597718	141	100	8	139	1	146	2.9e-10	37.7	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2852597720	312	81.87	2	308	35	314	6.2e-43	143.5	COG0208	Ribonucleotide reductase beta subunit, ferritin-like domain	348
2852597721	229	90.43	5	218	13	201	3.9e-22	76.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852597723	201	68.99	4	200	87	284	1.0e-16	57.6	COG4976	Predicted methyltransferase, contains TPR repeat	287
2852597724	464	98.34	4	464	2	474	1.7e-123	409.7	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
2852597725	121	72.92	29	115	17	86	4.7e-06	23	COG5470	Uncharacterized conserved protein, DUF1330 family	96
2852597728	142	57.23	1	102	10	104	6.0e-10	35.7	COG3467	Nitroimidazol reductase NimA or a related FMN-containing flavoprotein, pyridoxamine 5'-phosphate oxidase superfamily	166
2852597729	424	87.19	134	398	30	240	7.3e-28	95	COG1376	Lipoprotein-anchoring transpeptidase ErfK/SrfK	232
2852597731	162	96.23	1	162	5	157	2.7e-24	82.9	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2852597732	245	97.77	18	242	4	222	2.0e-47	158	COG0398	Uncharacterized membrane protein YdjX, TVP38/TMEM64 family, SNARE-associated domain	223
2852597733	276	89.93	1	262	6	246	1.1e-51	172.6	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852597734	521	98.64	3	291	3	293	2.9e-38	125.9	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852597735	525	85.39	450	525	3	78	1.0e-26	88	COG1264	Phosphotransferase system IIB components	88
2852597735	525	96.67	18	427	6	411	1.4e-116	386.2	COG1263	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific	393
2852597736	156	86.54	1	156	6	140	4.6e-41	136.7	COG2190	Phosphotransferase system IIA component	156
2852597737	261	99.17	1	244	1	238	6.5e-59	195.8	COG0363	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase	238
2852597738	379	98.95	1	377	3	379	6.9e-112	370.3	COG1820	N-acetylglucosamine-6-phosphate deacetylase	380
2852597739	259	65.31	7	257	10	137	4.2e-13	44.6	COG0693	Putative intracellular protease/amidase	188
2852597741	188	75.12	8	186	4	160	3.8e-13	47	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852597742	414	94.06	1	405	24	419	1.9e-84	280.5	COG2124	Cytochrome P450	411
2852597744	196	88.52	2	194	10	194	5.1e-21	72.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852597746	514	99.2	3	504	3	496	0.0e+00	559.4	COG2986	Histidine ammonia-lyase	498
2852597747	398	96.56	3	396	12	404	8.2e-88	291.4	COG1228	Imidazolonepropionase or related amidohydrolase	406
2852597748	448	93.16	8	438	24	418	1.3e-65	217.9	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
2852597749	408	91.39	20	407	34	415	3.6e-28	95	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2852597750	553	98.04	1	553	7	556	0.0e+00	924.5	COG2987	Urocanate hydratase	561
2852597751	261	98.78	6	254	2	244	6.3e-54	179	COG1414	DNA-binding transcriptional regulator, IclR family	246
2852597753	147	47.93	2	130	75	178	3.5e-05	19.8	COG5637	Uncharacterized membrane protein	217
2852597754	177	89.47	1	176	12	198	7.7e-16	55.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852597758	811	96.15	1	130	1	125	7.5e-34	112.2	COG3412	PTS-EIIA-like component DhaM of the dihydroxyacetone kinase DhaKLM complex	129
2852597758	811	97.75	152	242	2	88	3.4e-21	69.9	COG1925	Phosphotransferase system, HPr and related phosphotransfer proteins	88
2852597758	811	97.91	255	810	5	566	0.0e+00	558.5	COG1080	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria)	574
2852597759	210	66.46	1	208	15	232	6.7e-36	120.4	COG2376	Dihydroxyacetone kinase	323
2852597760	332	99.39	1	330	1	326	2.0e-128	424.5	COG2376	Dihydroxyacetone kinase	323
2852597761	253	97.14	3	233	4	241	4.5e-55	183	COG0580	Glycerol uptake facilitator and related aquaporins (Major Intrinsic Protein Family)	241
2852597762	247	99.59	3	239	1	245	5.5e-57	189	COG1414	DNA-binding transcriptional regulator, IclR family	246
2852597764	181	67.57	42	124	18	92	1.7e-04	15.7	COG2337	mRNA-degrading endonuclease, toxin component of the MazEF toxin-antitoxin module	112
2852597765	176	83.87	30	174	24	153	1.8e-23	79.4	COG2606	Cys-tRNA(Pro) deacylase, prolyl-tRNA editing enzyme YbaK/EbsC	155
2852597767	119	95.73	3	119	3	114	1.5e-38	128.3	COG3189	Uncharacterized conserved protein YeaO, DUF488 family	117
2852597769	472	91.52	199	467	10	268	9.2e-27	90	COG5607	CHAD domain (function unknown)	283
2852597770	210	85.56	22	204	19	178	2.5e-11	40.4	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2852597771	354	89.91	230	339	4	101	2.4e-61	100.9	COG1993	PII-like signaling protein	109
2852597771	354	90.83	2	106	5	103	2.4e-61	44.2	COG1993	PII-like signaling protein	109
2852597771	354	92.66	110	216	5	105	2.4e-61	52.6	COG1993	PII-like signaling protein	109
2852597772	121	93.65	2	121	7	124	4.0e-32	107.3	COG0239	Fluoride ion exporter CrcB/FEX, affects chromosome condensation	126
2852597773	132	96.83	5	129	3	124	8.2e-36	119.3	COG0239	Fluoride ion exporter CrcB/FEX, affects chromosome condensation	126
2852597774	544	99.05	25	544	2	520	0.0e+00	762.2	COG0033	Phosphoglucomutase	524
2852597775	419	53.52	17	216	3	207	2.7e-43	88.5	COG0477	MFS family permease	338
2852597775	419	54.83	214	415	2	211	2.7e-43	62.6	COG0477	MFS family permease	338
2852597777	216	93.3	10	210	8	202	1.4e-22	77.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852597779	182	34.93	6	175	10	82	1.2e-14	52.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852597780	423	94.54	18	419	23	420	1.6e-98	326.8	COG2124	Cytochrome P450	411
2852597781	96	50.38	1	94	12	77	4.6e-05	20.3	COG4270	Uncharacterized membrane protein	131
2852597782	173	72.83	2	172	3	136	7.9e-29	97.2	COG0431	NAD(P)H-dependent FMN reductase	184
2852597784	446	31.83	19	423	87	326	2.3e-01	6.5	COG0643	Chemotaxis protein histidine kinase CheA	716
2852597785	185	77.51	1	182	13	174	6.1e-19	65.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852597786	438	43.34	200	403	26	191	2.8e-13	18.4	COG0477	MFS family permease	338
2852597786	438	57.96	6	233	8	229	2.8e-13	31	COG0477	MFS family permease	338
2852597788	306	95.54	1	178	6	155	1.1e-40	128.3	COG1225	Peroxiredoxin	157
2852597790	331	16.63	241	328	37	103	1.1e-20	25.9	COG3391	DNA-binding beta-propeller fold protein YncE	381
2852597790	331	38.96	52	234	127	283	1.1e-20	50.4	COG3391	DNA-binding beta-propeller fold protein YncE	381
2852597792	267	97.01	2	263	3	262	2.9e-65	217	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852597793	155	92.95	2	154	4	148	1.1e-51	171.4	COG0328	Ribonuclease HI	154
2852597795	267	97.74	2	263	7	265	1.6e-62	207.7	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2852597796	1042	32.75	47	319	76	207	1.6e-60	50.7	COG3391	DNA-binding beta-propeller fold protein YncE	381
2852597796	1042	44.17	224	404	81	258	1.6e-60	90.5	COG3391	DNA-binding beta-propeller fold protein YncE	381
2852597796	1042	55.58	270	538	28	251	1.6e-60	91.2	COG3391	DNA-binding beta-propeller fold protein YncE	381
2852597798	567	84.47	7	438	2	398	2.0e-59	198.2	COG0515	Serine/threonine protein kinase	384
2852597799	631	63.18	5	175	28	154	2.5e-05	19.5	COG2112	Predicted Ser/Thr protein kinase	201
2852597800	635	63.18	6	176	28	154	6.2e-06	21.5	COG2112	Predicted Ser/Thr protein kinase	201
2852597801	286	93.82	43	286	11	268	4.9e-30	101.8	COG0575	CDP-diglyceride synthetase	265
2852597803	786	78.1	235	530	6	244	3.9e-67	223	COG1131	ABC-type multidrug transport system, ATPase component	293
2852597804	209	68.58	2	207	37	215	5.9e-35	117.2	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
2852597805	224	81.44	15	205	9	166	2.0e-09	34	COG0558	Phosphatidylglycerophosphate synthase	192
2852597806	227	97.77	6	219	2	220	2.7e-51	170.6	COG4565	Response regulator of citrate/malate metabolism	224
2852597807	562	98.14	3	555	8	534	2.6e-122	405.4	COG3290	Sensor histidine kinase regulating citrate/malate metabolism	537
2852597811	505	48.88	1	410	11	228	1.8e-48	157.6	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
2852597812	387	96.5	10	362	9	339	1.1e-48	162.4	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852597813	770	99.06	2	767	4	741	0.0e+00	629.7	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
2852597814	159	96.15	3	158	3	152	1.7e-65	216	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
2852597815	288	98.6	2	286	3	284	2.9e-66	220.5	COG1319	CO or xanthine dehydrogenase, FAD-binding subunit	284
2852597816	297	96.35	2	285	7	296	2.6e-38	128.4	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2852597817	154	94.84	5	154	5	151	6.4e-29	97.2	COG2606	Cys-tRNA(Pro) deacylase, prolyl-tRNA editing enzyme YbaK/EbsC	155
2852597818	369	97.49	1	368	1	389	1.4e-64	215.2	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852597819	412	98.75	1	412	1	394	4.9e-77	256.2	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852597820	185	28.57	76	148	101	154	2.5e-06	10.5	COG3945	Hemerythrin-like domain	189
2852597820	185	36.51	8	91	98	166	2.5e-06	14.9	COG3945	Hemerythrin-like domain	189
2852597821	133	48.76	2	128	121	238	9.1e-11	38.5	COG2202	PAS domain	232
2852597822	219	91.39	1	207	9	199	1.2e-22	78.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852597823	226	89	3	215	11	196	7.5e-18	62.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852597825	615	64.56	96	611	215	642	3.5e-103	342.3	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2852597826	713	74.71	60	253	57	251	8.5e-17	53.7	COG0476	Molybdopterin or thiamine biosynthesis adenylyltransferase	254
2852597828	298	97.21	13	298	8	286	3.4e-115	380.9	COG0788	Formyltetrahydrofolate hydrolase	287
2852597829	150	88.05	2	148	16	155	1.4e-41	137.7	COG2030	Acyl dehydratase	159
2852597830	273	99.25	3	271	2	267	1.5e-56	188.4	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852597831	389	97.74	1	386	7	396	4.9e-118	391.2	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852597832	249	98.88	2	249	3	267	1.7e-73	244.1	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852597833	404	100	1	402	1	394	6.8e-127	420.3	COG0183	Acetyl-CoA acetyltransferase	392
2852597834	397	98.25	6	396	4	395	3.4e-119	394.9	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852597835	222	90.52	2	220	16	225	4.7e-50	166.5	COG1802	DNA-binding transcriptional regulator, GntR family	230
2852597836	496	96.83	1	496	11	560	2.0e-76	253.4	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2852597837	492	96.3	1	492	11	557	3.9e-86	285.5	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2852597838	476	93.84	3	470	23	555	2.4e-56	183	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2852597839	261	88.68	2	259	6	240	1.3e-51	171.8	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2852597840	265	98.11	1	262	6	265	5.5e-64	212.6	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2852597841	265	98.11	2	262	6	265	6.3e-76	251.7	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2852597843	253	92.53	1	237	12	234	1.1e-38	129.4	COG2186	DNA-binding transcriptional regulator, FadR family	241
2852597844	286	87.17	1	273	5	235	2.6e-48	161.3	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2852597845	391	98.48	1	391	5	392	2.6e-100	332.8	COG0183	Acetyl-CoA acetyltransferase	392
2852597846	256	82.78	5	232	9	181	7.6e-16	55.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852597847	253	98.49	1	250	5	265	3.7e-71	235.9	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2852597848	265	98.51	3	263	3	266	3.5e-54	180.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852597849	335	14.38	246	335	254	296	8.8e-25	6.7	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
2852597849	335	54.85	11	221	4	167	8.8e-25	75.3	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
2852597851	275	99.25	4	268	3	265	5.2e-72	238.9	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2852597852	400	66.12	20	399	101	301	5.8e-18	61.8	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
2852597854	535	96.13	1	531	8	553	5.2e-65	216	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2852597855	278	66.12	9	272	99	299	2.2e-30	102.5	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
2852597856	350	24.81	7	121	4	102	3.2e-27	32.1	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852597856	350	37.09	134	345	242	389	3.2e-27	61.9	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852597857	398	98.25	2	388	5	396	4.7e-56	182.6	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852597858	213	46.95	5	209	44	174	2.6e-12	43.9	COG0500	SAM-dependent methyltransferase	257
2852597859	381	99.49	1	381	1	392	1.4e-63	211.8	COG0183	Acetyl-CoA acetyltransferase	392
2852597860	137	81.56	8	136	25	139	7.7e-23	77	COG1545	Uncharacterized OB-fold protein, contains Zn-ribbon domain	140
2852597861	124	71.68	2	123	7	130	1.5e-11	40.4	COG3688	Predicted RNA-binding protein containing a PIN domain	173
2852597862	408	98	2	407	9	401	6.2e-77	255.7	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2852597863	515	98.33	27	511	2	472	0.0e+00	475.3	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2852597864	399	92.4	4	397	32	420	5.1e-86	285.6	COG2124	Cytochrome P450	411
2852597865	258	98.13	1	250	5	267	2.0e-42	141.8	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852597866	492	90.61	4	454	40	473	1.4e-96	317.2	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2852597867	552	96.3	1	550	12	558	2.5e-68	227.1	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2852597868	204	76.6	77	201	27	134	1.1e-08	30.9	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
2852597869	203	92.72	10	203	12	202	3.2e-24	82.2	COG1335	Nicotinamidase-related amidase	205
2852597870	337	93.46	8	119	5	104	4.5e-10	35.4	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
2852597873	304	77.84	7	304	17	283	5.0e-44	146.8	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852597874	540	96.64	1	494	5	435	3.9e-99	329.2	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
2852597875	371	62.71	93	367	19	203	6.8e-04	15.8	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852597876	258	98.78	14	254	3	245	3.8e-56	186.2	COG1414	DNA-binding transcriptional regulator, IclR family	246
2852597877	312	59.56	9	301	5	250	4.4e-45	150.8	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
2852597878	402	96.76	2	402	8	395	6.9e-123	407	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2852597879	467	98.66	4	467	5	447	1.1e-68	228.2	COG2610	H+/gluconate symporter or related permease	442
2852597880	204	28.71	3	200	12	71	1.1e-16	58.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852597881	352	56.13	67	312	81	277	1.8e-05	20.1	COG3178	Predicted phosphotransferase, aminoglycoside/choline kinase (APH/ChoK) family	351
2852597882	124	79.84	2	124	11	113	4.8e-07	26.5	COG4922	Predicted SnoaL-like aldol condensation-catalyzing enzyme	129
2852597883	345	92.42	9	344	12	328	8.0e-37	123.4	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852597884	498	94.87	1	496	9	507	4.4e-123	407.7	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component	526
2852597885	348	94.17	1	346	16	338	7.2e-44	146.7	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852597886	411	95.49	3	409	18	419	1.5e-89	297.2	COG2124	Cytochrome P450	411
2852597888	430	81.91	52	377	54	302	2.3e-12	42.5	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
2852597889	63	90.77	1	63	7	65	4.0e-09	32.8	COG2879	Uncharacterized short protein YbdD, DUF466 family	65
2852597890	763	97.55	69	727	1	596	0.0e+00	802.7	COG1966	Carbon starvation protein CstA	575
2852597891	261	97.63	1	258	5	292	7.7e-32	107.6	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852597892	515	94.51	41	512	28	492	1.2e-125	416.5	COG1793	ATP-dependent DNA ligase	444
2852597893	121	29.05	5	61	4	46	2.7e-05	16.2	COG1610	Uncharacterized conserved protein YqeY	148
2852597893	121	44.59	47	120	23	88	2.7e-05	8.6	COG1610	Uncharacterized conserved protein YqeY	148
2852597894	516	92.39	156	419	2	268	1.6e-39	131.5	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
2852597895	255	99.25	1	252	2	267	8.5e-50	166.3	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852597896	578	98.74	1	552	3	550	0.0e+00	518.9	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
2852597897	446	34.8	241	437	84	186	1.1e-22	9.3	COG2321	Predicted metalloprotease	295
2852597897	446	81.42	1	237	49	289	1.1e-22	63.3	COG2321	Predicted metalloprotease	295
2852597898	224	82.5	1	110	10	108	2.9e-29	96.6	COG1733	DNA-binding transcriptional regulator, HxlR family	120
2852597899	275	55.91	6	267	25	180	7.6e-14	48.8	COG0500	SAM-dependent methyltransferase	257
2852597900	353	92.66	10	341	9	311	1.8e-51	171.6	COG3173	Predicted  kinase, aminoglycoside phosphotransferase (APT) family	321
2852597901	251	96.91	1	251	5	255	5.1e-30	101.2	COG0730	Uncharacterized membrane protein YfcA	258
2852597902	514	94.11	23	510	8	470	1.5e-58	194.9	COG0531	Amino acid transporter	466
2852597903	342	41.97	32	336	339	594	7.9e-25	83.7	COG2905	Signal-transduction protein containing cAMP-binding, CBS, and nucleotidyltransferase domains	610
2852597904	272	80.77	60	263	12	179	1.7e-26	89.4	COG2184	Fido, protein-threonine AMPylation domain	201
2852597906	493	93.59	53	492	25	418	1.8e-90	300.2	COG2124	Cytochrome P450	411
2852597907	206	92.34	3	205	8	200	2.6e-17	60.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852597908	285	91.79	4	259	4	249	4.0e-51	170.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852597909	394	98.93	1	394	2	371	3.8e-93	308.7	COG4637	Predicted ATPase	373
2852597910	349	96.26	4	347	1	360	2.9e-70	233.8	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
2852597911	202	67.94	12	199	7	148	1.5e-21	74.5	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852597912	180	73.91	4	179	1	136	4.6e-46	153.3	COG0431	NAD(P)H-dependent FMN reductase	184
2852597913	184	87.25	2	184	6	183	6.4e-51	169.4	COG3226	DNA-binding transcriptional regulator YbjK	204
2852597914	107	96.23	1	106	3	104	1.6e-28	95.8	COG2076	Multidrug transporter EmrE and related cation transporters	106
2852597915	80	93.75	1	75	1	75	2.6e-18	62.5	COG0695	Glutaredoxin	80
2852597916	147	97.2	1	144	3	141	1.6e-59	196.4	COG1780	Protein involved in ribonucleotide reduction	141
2852597917	722	99.61	21	721	3	762	0.0e+00	718.7	COG0209	Ribonucleotide reductase alpha subunit	696
2852597920	395	92.87	2	395	3	380	2.2e-69	231	COG0644	Dehydrogenase (flavoprotein)	396
2852597921	246	86.6	16	225	5	185	1.2e-20	71.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852597923	504	97.31	9	459	6	439	0.0e+00	440.8	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
2852597924	324	92.98	3	322	23	340	6.8e-99	327.5	COG0208	Ribonucleotide reductase beta subunit, ferritin-like domain	348
2852597925	57	85.07	1	57	1	57	6.6e-15	51.6	COG3237	Uncharacterized conserved protein YjbJ, UPF0337 family	67
2852597926	282	93	1	282	9	287	2.0e-50	168.2	COG3315	O-Methyltransferase involved in polyketide biosynthesis	297
2852597927	113	25.55	31	113	98	132	7.1e-08	29.1	COG2764	Uncharacterized conserved protein PhnB, glyoxalase superfamily	136
2852597928	54	35.14	3	47	71	109	2.8e-03	14.6	COG4226	Predicted nuclease of the RNAse H fold, HicB family	111
2852597929	531	92.68	13	526	11	466	7.6e-38	126.7	COG0531	Amino acid transporter	466
2852597930	349	99.41	1	346	2	340	1.3e-125	415.4	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
2852597931	91	83.7	1	86	5	81	6.4e-13	45.6	COG2350	Uncharacterized conserved protein YciI, contains a putative active-site phosphohistidine	92
2852597932	361	96.6	10	361	7	319	5.6e-48	160.3	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
2852597933	581	95.25	22	571	6	547	0.0e+00	743.6	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
2852597934	413	97.78	5	95	2	89	4.5e-25	80.1	COG3830	ACT domain, binds amino acids and other small ligands	90
2852597934	413	99.06	178	388	2	211	7.6e-75	247.2	COG0560	Phosphoserine phosphatase	212
2852597935	309	90.2	1	309	3	315	1.3e-101	336.6	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
2852597936	481	98.68	27	471	3	452	6.8e-92	305.1	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
2852597938	231	91.9	1	201	4	196	8.0e-48	159.1	COG2364	Uncharacterized membrane protein YczE	210
2852597939	217	68.79	4	213	79	272	1.9e-44	148.1	COG1072	Panthothenate kinase	283
2852597940	281	91.44	2	239	22	256	4.2e-89	294.6	COG1119	ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA	257
2852597941	274	40.7	1	221	12	81	3.0e-07	26.2	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2852597942	215	80.38	1	214	7	219	2.4e-58	194.1	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2852597943	322	59	31	263	16	156	6.0e-22	74.3	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
2852597946	442	91.67	66	442	27	389	8.6e-28	92.4	COG1520	Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat	370
2852597947	245	92.63	32	229	9	184	7.3e-40	133.2	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
2852597948	255	78.81	5	111	11	103	6.5e-14	48.3	COG0640	DNA-binding transcriptional regulator, ArsR family	110
2852597949	123	28.9	1	113	4	79	8.6e-16	55.6	COG2214	Curved DNA-binding protein CbpA, contains a DnaJ-like domain	237
2852597950	140	86.99	1	130	19	145	3.0e-27	91.8	COG0071	Molecular chaperone IbpA, HSP20 family	146
2852597951	130	79.55	14	129	1	105	2.0e-25	86	COG0789	DNA-binding transcriptional regulator, MerR family	124
2852597952	413	97.8	1	395	4	403	5.7e-57	190.5	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2852597953	507	99.6	7	507	2	503	0.0e+00	587.7	COG1543	Predicted glycosyl hydrolase, contains GH57 and DUF1957 domains	504
2852597954	263	59.5	14	258	44	209	7.1e-21	71.6	COG0500	SAM-dependent methyltransferase	257
2852597955	266	99.23	2	266	2	260	5.8e-82	271.3	COG2086	Electron transfer flavoprotein, alpha and beta subunits	260
2852597956	318	99.37	2	316	2	317	2.3e-107	355.9	COG2025	Electron transfer flavoprotein, alpha subunit	313
2852597957	133	48.85	4	121	54	117	2.2e-11	40.3	COG1917	Cupin domain protein related to quercetin dioxygenase	131
2852597958	217	95.83	1	215	3	209	2.3e-26	88.1	COG0778	Nitroreductase	207
2852597959	282	88.05	2	276	30	287	2.1e-73	243.6	COG3176	Putative hemolysin	292
2852597960	275	66.67	33	235	14	187	7.9e-33	110.2	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
2852597961	399	98.45	5	393	2	381	0.0e+00	476.2	COG1104	Cysteine sulfinate desulfinase/cysteine desulfurase or related enzyme	386
2852597962	355	98.32	1	355	4	354	5.4e-112	371	COG0482	tRNA U34 2-thiouridine synthase MnmA/TrmU, contains the PP-loop ATPase domain	356
2852597964	336	61.93	92	332	125	329	2.1e-08	29.8	COG0620	Methionine synthase II (cobalamin-independent)	330
2852597965	162	94.27	1	157	8	155	5.6e-13	44.6	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
2852597966	113	65.25	7	113	12	88	5.1e-11	39.6	COG0640	DNA-binding transcriptional regulator, ArsR family	110
2852597968	872	85	794	871	10	77	2.5e-18	61	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2852597969	535	93.31	18	535	26	555	7.4e-114	377.5	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2852597970	134	89.92	14	133	5	111	1.8e-06	24.3	COG2315	Predicted DNA-binding protein with ?double-wing? structural motif, MmcQ/YjbR family	118
2852597971	699	99.26	16	693	5	673	0.0e+00	823.2	COG0272	NAD-dependent DNA ligase	667
2852597974	99	97.92	2	97	2	95	5.4e-33	109.8	COG0721	Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit	96
2852597975	493	98.54	1	492	1	474	0.0e+00	591.5	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
2852597976	343	90.76	1	340	3	326	1.3e-113	376	COG0205	6-phosphofructokinase	347
2852597977	292	67.54	60	284	78	258	8.3e-14	47.7	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
2852597978	126	96.97	4	126	1	128	4.8e-20	68.7	COG0789	DNA-binding transcriptional regulator, MerR family	124
2852597980	232	27.9	140	216	124	200	1.9e-21	19.7	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
2852597980	232	40.94	1	117	1	113	1.9e-21	56.2	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
2852597981	157	84.21	18	147	16	127	3.8e-23	78.4	COG1846	DNA-binding transcriptional regulator, MarR family	126
2852597982	500	98.76	13	500	4	480	0.0e+00	627.5	COG0064	Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit	483
2852597983	209	93.78	4	208	4	199	2.7e-18	63.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852597984	246	98.51	2	245	3	266	1.5e-66	221.3	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852597985	105	98.11	1	105	2	105	8.8e-33	109.5	COG2076	Multidrug transporter EmrE and related cation transporters	106
2852597986	373	98.55	3	373	6	412	6.8e-55	183.2	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
2852597987	266	95.14	87	236	6	142	5.1e-23	78.7	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
2852597990	621	99.46	40	607	2	553	0.0e+00	748.2	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
2852597991	168	98.15	2	164	3	161	1.4e-65	216.6	COG0440	Acetolactate synthase, small subunit	163
2852597992	337	97.04	1	336	3	330	0.0e+00	505.7	COG0059	Ketol-acid reductoisomerase	338
2852597993	199	92.02	1	198	3	198	1.4e-34	116.4	COG0655	Multimeric flavodoxin WrbA	207
2852597994	481	98.39	2	475	4	492	1.3e-90	301.3	COG1233	Phytoene dehydrogenase-related protein	487
2852597995	528	95.4	2	317	5	315	2.3e-115	381	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
2852597996	336	97.41	1	336	5	343	1.1e-119	396.1	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
2852598000	397	44.91	211	396	20	191	2.9e-19	26.3	COG0477	MFS family permease	338
2852598000	397	49.87	10	217	3	193	2.9e-19	45.5	COG0477	MFS family permease	338
2852598001	261	88.28	10	260	31	271	9.0e-88	290.8	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
2852598002	491	97.5	1	481	9	476	1.8e-126	419.5	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
2852598005	405	92.82	1	396	7	394	1.3e-65	218.4	COG4102	Uncharacterized conserved protein, DUF1501 family	418
2852598006	438	63.1	52	397	134	446	1.2e-59	198.6	COG5267	Uncharacterized conserved protein, DUF1800 family	496
2852598008	233	98.78	8	233	2	244	4.0e-57	189.3	COG1414	DNA-binding transcriptional regulator, IclR family	246
2852598009	477	99.3	5	476	3	428	0.0e+00	631.1	COG0065	Homoaconitase/3-isopropylmalate dehydratase large subunit	423
2852598010	197	98.45	1	192	1	190	4.2e-68	225.4	COG0066	3-isopropylmalate dehydratase small subunit	191
2852598011	309	80.81	10	145	17	155	4.9e-18	61.3	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2852598012	717	97.14	29	716	8	686	0.0e+00	970.3	COG0855	Polyphosphate kinase	696
2852598013	217	91.47	12	217	2	194	4.0e-59	196.2	COG1920	2-phospho-L-lactate guanylyltransferase, coenzyme F420 biosynthesis enzyme, CobY/MobA/RfbA family	210
2852598014	332	98.78	2	332	5	329	1.1e-122	405.9	COG0240	Glycerol-3-phosphate dehydrogenase	329
2852598015	367	96.73	4	367	10	393	7.7e-95	314.2	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
2852598016	373	99.06	10	366	4	318	6.5e-119	393.2	COG1181	D-alanine-D-alanine ligase and related ATP-grasp enzymes	317
2852598018	220	98.58	8	218	3	210	5.0e-63	209	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2852598019	415	94.67	40	401	21	375	1.2e-40	136.2	COG4585	Signal transduction histidine kinase	365
2852598021	80	48.73	1	79	69	145	1.3e-03	15.5	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2852598022	317	99.38	10	317	3	320	2.9e-90	298.9	COG0611	Thiamine monophosphate kinase	317
2852598023	227	98.65	8	227	3	221	6.3e-79	261.3	COG0692	Uracil DNA glycosylase	223
2852598025	263	93.9	11	251	3	233	1.9e-31	104.9	COG1414	DNA-binding transcriptional regulator, IclR family	246
2852598027	64	84.42	1	64	1	65	1.7e-24	82.4	COG0227	Ribosomal protein L28	77
2852598028	544	99.45	2	544	4	543	3.8e-130	431.6	COG1461	Predicted kinase related to dihydroxyacetone kinase	542
2852598029	736	95.28	4	727	22	667	0.0e+00	764.9	COG1200	RecG-like helicase	677
2852598032	279	97.16	6	278	5	278	1.4e-98	325.7	COG0656	Aldo/keto reductase, related to diketogulonate reductase	280
2852598033	276	97.52	1	274	6	280	1.2e-107	355.6	COG0656	Aldo/keto reductase, related to diketogulonate reductase	280
2852598034	368	92.14	43	366	25	317	7.3e-76	252.2	COG0657	Acetyl esterase/lipase	312
2852598035	276	81.53	1	240	43	245	2.0e-28	95.8	COG1651	Protein-disulfide isomerase	244
2852598036	210	88.46	19	203	11	148	1.8e-43	143	COG4243	Uncharacterized membrane protein	156
2852598037	1127	99.3	1	1127	7	1147	0.0e+00	1727.1	COG1038	Pyruvate carboxylase	1149
2852598038	173	88.3	1	169	20	185	4.1e-47	156.7	COG0742	16S rRNA G966 N2-methylase RsmD	187
2852598039	240	75.42	11	140	14	102	2.5e-14	49.7	COG0640	DNA-binding transcriptional regulator, ArsR family	110
2852598040	137	86.76	1	129	7	124	5.9e-04	15.3	COG3631	Ketosteroid isomerase-related protein	133
2852598041	158	98.11	1	157	3	158	4.7e-63	208.3	COG0669	Phosphopantetheine adenylyltransferase	159
2852598042	188	37.43	73	157	79	142	8.7e-05	6.2	COG5592	Hemerythrin superfamily protein	171
2852598042	188	43.27	3	101	73	146	8.7e-05	15	COG5592	Hemerythrin superfamily protein	171
2852598043	245	95.91	2	225	9	219	3.1e-42	141.3	COG3599	Cell division septum initiation DivIVA, interacts with FtsZ, MinD and other proteins	212
2852598044	194	97.21	11	191	5	178	4.5e-43	143.8	COG1399	Uncharacterized metal-binding protein YceD, DUF177 family	176
2852598045	233	93.22	2	230	11	230	2.0e-69	229.7	COG0571	dsRNA-specific ribonuclease	235
2852598046	285	100	1	278	1	274	3.7e-88	292.3	COG0266	Formamidopyrimidine-DNA glycosylase	273
2852598047	138	97.08	1	134	1	133	4.8e-23	77.9	COG1765	Uncharacterized OsmC-related protein	137
2852598048	94	93.55	4	94	4	90	5.7e-26	87.5	COG1254	Acylphosphatase	92
2852598049	1195	99.66	1	1190	1	1164	0.0e+00	1008.4	COG1196	Chromosome segregation ATPase	1163
2852598050	341	93.63	6	340	12	349	2.3e-82	272.8	COG1304	FMN-dependent dehydrogenase, includes L-lactate dehydrogenase and type II isopentenyl diphosphate isomerase	360
2852598051	434	90.56	86	434	34	359	5.2e-112	371	COG0552	Signal recognition particle GTPase	340
2852598052	460	98.54	10	447	2	407	0.0e+00	496.1	COG0004	Ammonia channel protein AmtB	409
2852598053	112	100	1	112	1	112	3.5e-47	156.1	COG0347	Nitrogen regulatory protein PII	112
2852598054	840	98.04	28	830	10	859	0.0e+00	641.9	COG2844	UTP:GlnB (protein PII) uridylyltransferase	867
2852598055	519	97.79	1	467	1	442	0.0e+00	611.8	COG0541	Signal recognition particle GTPase	451
2852598056	363	25.8	24	148	57	161	8.4e-49	50.9	COG1228	Imidazolonepropionase or related amidohydrolase	406
2852598056	363	44.96	160	363	219	401	8.4e-49	113.5	COG1228	Imidazolonepropionase or related amidohydrolase	406
2852598057	278	69.21	1	278	12	283	9.4e-73	242.2	COG1686	D-alanyl-D-alanine carboxypeptidase	389
2852598058	292	69.72	2	291	9	282	3.9e-75	249.9	COG1686	D-alanyl-D-alanine carboxypeptidase	389
2852598060	209	47.28	30	184	43	155	2.9e-16	55.6	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
2852598062	174	88.89	2	89	1	80	2.2e-30	100.4	COG0228	Ribosomal protein S16	87
2852598063	80	98.68	5	80	1	75	1.9e-27	91.4	COG1837	Predicted RNA-binding protein YlqC, contains KH domain, UPF0109 family	76
2852598064	172	95.4	1	170	8	173	5.9e-49	162.5	COG0806	Ribosomal 30S subunit maturation factor RimM, required for 16S rRNA processing	174
2852598065	225	91.8	1	225	1	224	1.8e-97	321.6	COG0336	tRNA G37 N-methylase TrmD	240
2852598067	113	90.98	1	113	12	122	4.3e-49	162.1	COG0335	Ribosomal protein L19	115
2852598068	281	96.59	35	178	6	175	4.4e-29	94.7	COG0681	Signal peptidase I	166
2852598069	230	94.06	22	211	2	191	9.2e-58	192.1	COG0164	Ribonuclease HII	199
2852598071	365	98	5	365	4	346	4.5e-81	268.9	COG3804	Uncharacterized protein	350
2852598072	399	93.11	2	398	25	416	2.7e-84	279.9	COG2124	Cytochrome P450	411
2852598073	447	62.2	257	443	19	148	2.9e-29	52.2	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852598073	447	74.64	12	239	12	167	2.9e-29	49.2	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852598075	213	98.15	1	210	4	215	1.8e-19	66.8	COG0778	Nitroreductase	207
2852598077	324	92.54	2	258	3	250	1.2e-48	162.4	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852598078	560	66.06	294	522	48	228	2.2e-06	23.9	COG1240	Mg-chelatase subunit ChlD	261
2852598079	283	74.55	8	259	23	268	3.1e-42	141.3	COG0714	MoxR-like ATPase	329
2852598080	370	81.42	5	353	46	343	2.2e-12	42.6	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2852598082	339	78.73	1	274	4	214	3.4e-47	157.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852598083	494	98.54	11	494	2	473	0.0e+00	476.2	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2852598084	404	95.49	4	403	18	419	1.4e-95	317.1	COG2124	Cytochrome P450	411
2852598085	434	92.87	8	432	29	419	6.7e-76	252.3	COG2124	Cytochrome P450	411
2852598086	139	92.31	1	127	6	125	5.3e-26	87.6	COG4308	Limonene-1,2-epoxide hydrolase	130
2852598087	356	96.88	1	309	3	313	5.3e-41	137.7	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2852598089	408	88.6	5	402	48	420	6.7e-81	268.8	COG2124	Cytochrome P450	411
2852598090	335	99.09	7	331	3	330	1.3e-61	205.3	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2852598091	64	95.59	1	61	1	65	5.6e-19	64.8	COG1141	Ferredoxin	68
2852598092	201	66.99	1	188	20	159	1.1e-15	55.5	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852598093	567	95.77	24	562	13	556	1.7e-77	256.9	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2852598094	399	62.89	283	399	53	152	4.0e-13	19.6	COG2030	Acyl dehydratase	159
2852598094	399	85.53	4	168	13	148	4.0e-13	21.6	COG2030	Acyl dehydratase	159
2852598095	332	22.06	2	91	4	91	1.2e-33	10.1	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852598095	332	62.41	95	329	143	391	1.2e-33	106.7	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852598096	390	26.32	273	390	293	397	2.5e-74	39.4	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852598096	390	62.66	2	260	5	254	2.5e-74	209.2	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852598097	276	86.04	1	267	6	233	4.2e-33	111.3	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2852598098	122	61.61	4	115	9	77	6.8e-04	16.2	COG4538	Uncharacterized protein	112
2852598099	541	94.54	2	527	10	546	5.0e-68	226.2	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2852598100	441	94.06	11	432	25	420	3.7e-76	253.1	COG2124	Cytochrome P450	411
2852598101	616	87.89	59	554	2	393	1.5e-74	247.9	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
2852598103	293	98.88	3	284	2	266	1.9e-43	145.4	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852598104	216	92.82	11	216	9	202	5.4e-18	62.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852598107	457	89.63	21	457	32	446	9.0e-80	264.8	COG0076	Glutamate or tyrosine decarboxylase or a related PLP-dependent protein	460
2852598108	169	78.2	16	151	16	119	9.0e-17	57.7	COG1846	DNA-binding transcriptional regulator, MarR family	126
2852598110	968	97.77	14	958	8	928	0.0e+00	924.3	COG2409	Uncharacterized membrane protein YdfJ, MMPL/SSD domain	937
2852598111	294	97.01	2	294	4	295	2.9e-57	191.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
2852598112	396	94.68	1	383	9	382	8.9e-35	116.5	COG2814	Predicted arabinose efflux permease, MFS family	394
2852598113	157	77.78	4	152	2	120	8.9e-16	54.2	COG1246	N-acetylglutamate synthase or related acetyltransferase, GNAT family	153
2852598114	257	95.19	1	257	8	264	2.0e-74	246.8	COG0647	Ribonucleotide monophosphatase NagD, HAD superfamily	269
2852598116	301	89.32	1	298	27	302	4.8e-30	101.1	COG0010	Arginase family enzyme	305
2852598117	715	88.27	5	364	20	335	4.0e-37	123.9	COG1071	TPP-dependent pyruvate or acetoin dehydrogenase subunit alpha	358
2852598117	715	98.46	380	713	3	321	6.5e-61	202.2	COG0022	Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component	324
2852598118	399	98.25	2	398	7	400	6.0e-64	212.8	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2852598119	266	96.55	1	266	5	284	7.3e-54	174.9	COG1946	Acyl-CoA thioesterase	289
2852598120	836	19.75	2	108	18	126	1.6e-42	14.8	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2852598120	836	52.17	92	440	181	468	1.6e-42	125.9	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2852598121	347	89.8	1	346	4	320	1.1e-99	330.5	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2852598122	532	97.24	24	531	8	536	1.7e-109	363	COG1178	ABC-type Fe3+ transport system, permease component	540
2852598123	338	95.68	47	337	1	288	2.0e-60	201.1	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
2852598126	122	88.6	6	120	3	103	1.6e-34	114.7	COG0792	Predicted endonuclease distantly related to archaeal Holliday junction resolvase	114
2852598127	503	98.98	15	503	2	488	0.0e+00	560.3	COG0606	Predicted ATPase with chaperone activity	490
2852598128	374	99.16	1	373	1	356	8.9e-97	320.8	COG0758	Predicted Rossmann fold nucleotide-binding protein DprA/Smf involved in DNA uptake	350
2852598130	282	94.36	1	267	15	265	8.8e-82	270.9	COG2375	NADPH-dependent ferric siderophore reductase, contains FAD-binding and SIP domains	265
2852598131	591	97.74	14	464	7	396	7.4e-87	288.7	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852598132	194	80.86	1	193	11	179	1.9e-19	67.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852598133	386	96.4	26	386	3	350	1.1e-92	307	COG1304	FMN-dependent dehydrogenase, includes L-lactate dehydrogenase and type II isopentenyl diphosphate isomerase	360
2852598134	300	98	1	300	7	300	7.2e-89	294.5	COG4974	Site-specific recombinase XerD	300
2852598135	162	37.34	15	157	172	289	3.0e-26	89.6	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
2852598136	276	89.84	1	264	3	232	3.9e-110	363.3	COG0052	Ribosomal protein S2	252
2852598137	271	93.27	1	271	2	278	9.2e-94	310.4	COG0264	Translation elongation factor EF-Ts	296
2852598138	468	98.13	9	468	6	477	1.8e-104	347	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
2852598139	254	57.35	3	243	44	203	6.0e-11	39.5	COG0500	SAM-dependent methyltransferase	257
2852598141	189	24.12	27	187	385	507	1.3e-11	41.1	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
2852598142	243	96.46	23	243	2	219	6.0e-80	264.2	COG1136	ABC-type lipoprotein export system, ATPase component	226
2852598143	500	92.48	18	492	25	479	3.0e-33	111.4	COG0531	Amino acid transporter	466
2852598144	657	95.41	2	650	28	651	0.0e+00	752.1	COG3733	Cu2+-containing amine oxidase	654
2852598145	312	73.75	51	229	39	156	8.1e-03	11.6	COG4244	Uncharacterized membrane protein	160
2852598146	143	91.73	10	140	5	126	1.7e-17	60.2	COG1846	DNA-binding transcriptional regulator, MarR family	126
2852598147	228	58.42	5	226	48	210	1.6e-10	38.1	COG0500	SAM-dependent methyltransferase	257
2852598148	252	99.16	18	252	2	237	9.6e-90	296.8	COG0528	Uridylate kinase	238
2852598149	185	97.86	1	185	5	187	1.2e-74	246.3	COG0233	Ribosome recycling factor	187
2852598150	286	97.09	21	286	6	272	3.5e-55	184	COG0575	CDP-diglyceride synthetase	265
2852598151	315	93.69	3	292	15	296	1.3e-24	83.4	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2852598152	363	97.71	16	363	2	342	3.9e-125	413.8	COG0820	Adenine C2-methylase RlmN of 23S rRNA A2503 and tRNA A37	349
2852598153	275	85.61	5	141	2	114	8.4e-21	71	COG0789	DNA-binding transcriptional regulator, MerR family	124
2852598155	283	92.16	1	254	5	251	2.8e-48	161.3	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852598157	494	98.33	15	493	2	472	0.0e+00	468.2	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2852598158	182	65.07	5	180	13	148	1.1e-13	48.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852598159	388	95.01	1	388	6	386	8.7e-104	344.1	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2852598160	174	78.47	3	173	14	177	6.1e-15	52.2	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852598161	417	96.2	11	416	12	416	3.2e-86	286.1	COG2124	Cytochrome P450	411
2852598162	63	98.53	1	63	1	67	1.4e-18	63.6	COG1141	Ferredoxin	68
2852598164	297	87.06	14	297	18	286	5.3e-40	133.9	COG3386	Sugar lactone lactonase YvrE	307
2852598166	404	94.06	1	404	23	418	2.2e-68	227.6	COG2124	Cytochrome P450	411
2852598167	308	18.41	1	84	21	85	1.2e-41	34.3	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
2852598167	308	65.16	79	308	122	351	1.2e-41	104.9	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
2852598168	252	98.04	1	248	5	254	4.1e-49	163.3	COG3836	2-keto-3-deoxy-L-rhamnonate aldolase RhmA	255
2852598169	235	98.88	1	233	3	267	8.0e-61	202.4	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852598170	504	93.27	1	437	8	423	2.6e-100	333.2	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
2852598171	312	85.53	5	302	46	317	4.0e-63	210.3	COG0657	Acetyl esterase/lipase	312
2852598173	376	98.75	5	370	4	397	6.4e-57	181.3	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852598174	310	93.59	5	310	18	338	8.8e-62	205.5	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852598175	277	26.42	15	122	91	132	5.8e-14	8.4	COG2030	Acyl dehydratase	159
2852598175	277	51.57	142	273	34	115	5.8e-14	39.1	COG2030	Acyl dehydratase	159
2852598176	305	60.64	5	301	18	225	5.2e-59	196.2	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852598177	437	98.35	1	416	1	417	2.8e-62	204.5	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
2852598178	525	88.8	4	398	3	351	2.1e-71	237.7	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2852598179	298	95.59	22	292	12	293	7.9e-28	94.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852598180	275	98.64	8	269	3	293	7.9e-41	137.1	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852598181	223	70.33	12	217	3	149	6.3e-16	56.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852598182	396	93.35	3	395	27	419	9.2e-78	258.5	COG2124	Cytochrome P450	411
2852598183	515	97.46	4	393	3	385	1.3e-70	235	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2852598184	621	96.65	9	573	12	560	9.4e-86	284.6	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2852598185	312	89.38	6	311	21	264	1.4e-48	162.1	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
2852598187	219	90.91	8	214	8	197	2.9e-15	53.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852598188	361	70	1	303	43	301	2.9e-55	184.3	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852598189	341	85.95	4	338	11	328	8.0e-67	222.3	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852598190	361	92.16	3	361	12	352	3.9e-59	197.1	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852598191	486	94.32	1	368	1	349	1.9e-72	240.8	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852598192	459	86.22	1	368	1	319	1.1e-57	192.2	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852598193	545	98.38	1	365	1	364	5.3e-67	222.9	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852598196	195	65.55	7	192	15	151	3.8e-17	59.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852598197	338	81.36	1	334	2	337	2.4e-62	207.7	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
2852598198	318	97.74	1	317	6	308	0.0e+00	476.9	COG4569	Acetaldehyde dehydrogenase (acetylating)	310
2852598199	210	86.12	4	207	4	183	3.4e-25	86.3	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852598200	505	96.95	3	385	2	382	5.6e-71	236.3	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2852598201	288	98.98	7	282	3	294	7.5e-46	153.6	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852598204	608	96.74	13	469	10	395	7.3e-81	269	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852598205	225	33.33	21	74	19	62	6.0e-40	20.2	COG2343	Uncharacterized conserved protein, DUF427 family	132
2852598205	225	84.85	94	223	13	124	6.0e-40	110.4	COG2343	Uncharacterized conserved protein, DUF427 family	132
2852598209	277	99.25	3	276	2	267	9.3e-48	159.6	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852598210	427	99.35	1	427	3	462	0.0e+00	450.6	COG0415	Deoxyribodipyrimidine photolyase	461
2852598211	290	60.93	4	281	18	226	5.3e-45	150.4	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852598212	137	93.13	3	135	9	130	3.2e-20	68.9	COG5485	Predicted ester cyclase	131
2852598215	288	85.03	2	166	9	167	3.0e-22	75.9	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2852598217	280	97.46	2	273	2	270	3.6e-35	118	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
2852598218	282	85.48	1	167	15	173	8.3e-36	119.1	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2852598219	234	91.95	43	215	6	165	4.5e-61	202.2	COG0225	Peptide methionine sulfoxide reductase MsrA	174
2852598220	162	88.65	36	162	3	127	5.0e-52	171.8	COG0229	Peptide methionine sulfoxide reductase MsrB	140
2852598221	560	50	254	484	25	99	6.2e-09	32.1	COG0526	Thiol-disulfide isomerase or thioredoxin	127
2852598221	560	94.27	1	206	13	226	1.3e-40	135.7	COG0785	Cytochrome c biogenesis protein CcdA	220
2852598222	213	79.02	23	213	40	201	1.0e-45	152.8	COG2335	Uncaracterized surface protein containing fasciclin (FAS1) repeats	187
2852598223	385	98.45	3	382	3	382	0.0e+00	492.1	COG0743	1-deoxy-D-xylulose 5-phosphate reductoisomerase	385
2852598224	408	99.25	3	405	1	399	3.5e-67	224	COG0750	Membrane-associated protease RseP, regulator of RpoE activity	375
2852598225	387	98.65	19	379	2	366	0.0e+00	490.8	COG0821	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase IspG/GcpE	361
2852598226	284	100	1	283	1	268	5.0e-71	235.9	COG3393	Predicted acetyltransferase, GNAT family	268
2852598229	219	37.65	64	216	47	107	1.7e-03	15.1	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2852598235	199	88.04	8	198	8	191	1.6e-18	64.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852598236	148	83.82	3	126	13	126	7.0e-06	22.5	COG3631	Ketosteroid isomerase-related protein	133
2852598237	285	97.42	37	285	5	306	5.1e-86	285	COG0024	Methionine aminopeptidase	255
2852598238	489	99.18	2	475	3	484	0.0e+00	541.6	COG1492	Cobyric acid synthase	486
2852598239	344	99.7	2	328	1	333	8.0e-85	281.5	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2852598240	339	31.08	2	142	18	132	1.4e-25	44.1	COG1482	Mannose-6-phosphate isomerase, class I	312
2852598240	339	43.51	143	326	205	365	1.4e-25	40.2	COG1482	Mannose-6-phosphate isomerase, class I	312
2852598241	253	47.7	1	253	7	245	2.1e-87	290.3	COG1129	ABC-type sugar transport system, ATPase component	500
2852598242	357	96.24	24	347	8	314	8.6e-85	280.7	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
2852598243	352	92.66	37	349	14	316	1.9e-60	200.6	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
2852598244	217	90.5	7	213	2	201	3.4e-44	147.8	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
2852598245	242	99.25	2	240	2	267	3.0e-56	187.4	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852598247	187	57.97	2	185	5	175	8.8e-09	32.1	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852598248	586	74.69	115	250	39	159	5.6e-09	30.4	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2852598248	586	94.03	269	570	3	301	1.9e-33	112.1	COG1181	D-alanine-D-alanine ligase and related ATP-grasp enzymes	317
2852598249	599	99.45	1	594	2	546	0.0e+00	476	COG0367	Asparagine synthetase B (glutamine-hydrolyzing)	542
2852598250	522	96.75	7	518	7	482	1.1e-45	152.5	COG0531	Amino acid transporter	466
2852598251	524	93.9	18	502	7	468	4.3e-61	203.4	COG0531	Amino acid transporter	466
2852598252	497	98.01	2	489	5	496	2.9e-123	408.5	COG1070	Sugar (pentulose or hexulose) kinase	502
2852598253	451	87.96	26	449	23	336	2.7e-42	141.1	COG0371	Glycerol dehydrogenase or related enzyme, iron-containing ADH family	360
2852598255	249	95.4	2	235	10	237	5.6e-53	176.3	COG2188	DNA-binding transcriptional regulator, GntR family	236
2852598256	452	98.88	5	451	4	444	1.4e-122	406.1	COG0174	Glutamine synthetase	443
2852598257	248	96.72	3	247	2	237	4.7e-71	235.5	COG2071	Gamma-glutamyl-gamma-aminobutyrate hydrolase PuuD (putrescine degradation), contains GATase1-like domain	243
2852598258	454	94.99	2	453	19	473	0.0e+00	524.5	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2852598259	257	99.25	5	252	2	267	7.1e-72	238.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852598260	239	91.29	16	239	13	232	2.9e-40	134.6	COG2186	DNA-binding transcriptional regulator, FadR family	241
2852598261	259	99.58	1	242	1	239	3.1e-64	213.2	COG0363	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase	238
2852598262	402	96.77	80	386	3	302	7.8e-55	182.4	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
2852598263	481	94.11	10	472	8	470	5.0e-56	186.6	COG0531	Amino acid transporter	466
2852598265	154	66.45	9	146	50	150	2.9e-14	49.7	COG0782	Transcription elongation factor, GreA/GreB family	151
2852598266	149	90.79	1	141	9	146	1.6e-13	47.5	COG0782	Transcription elongation factor, GreA/GreB family	151
2852598267	421	96.65	9	421	5	379	6.5e-63	209.5	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2852598268	253	10.77	38	116	21	76	2.1e+00	3	COG0815	Apolipoprotein N-acyltransferase	518
2852598268	253	17.5	123	237	18	108	2.1e+00	8.6	COG0815	Apolipoprotein N-acyltransferase	518
2852598270	109	78.81	13	108	10	102	5.3e-15	52.2	COG0640	DNA-binding transcriptional regulator, ArsR family	110
2852598271	267	97.07	13	254	6	237	1.5e-65	217.5	COG2188	DNA-binding transcriptional regulator, GntR family	236
2852598272	246	88.24	15	233	4	198	2.5e-38	128.6	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
2852598273	306	85.46	13	292	16	256	4.1e-23	78.6	COG0510	Thiamine kinase and related kinases	269
2852598274	815	98.71	6	392	2	384	1.4e-83	277.4	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2852598274	815	99.48	419	815	2	384	6.9e-102	337.3	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
2852598275	367	96.2	5	358	10	338	2.2e-114	378.7	COG3376	High-affinity nickel permease	342
2852598276	471	99.34	1	456	3	454	1.1e-123	410	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
2852598277	340	91.56	28	330	24	305	1.7e-55	184.6	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
2852598278	500	99.3	6	474	3	429	2.3e-118	392	COG0579	L-2-hydroxyglutarate oxidase LhgO	429
2852598279	153	96.77	1	152	1	150	2.0e-52	173.7	COG2153	Predicted N-acyltransferase, GNAT family	155
2852598280	610	12.77	1	60	13	66	1.6e-128	72.2	COG1239	Mg-chelatase subunit ChlI	423
2852598280	610	68.79	57	380	105	395	1.6e-128	360.6	COG1239	Mg-chelatase subunit ChlI	423
2852598281	204	95.96	1	204	9	198	1.9e-70	233.2	COG2109	ATP:corrinoid adenosyltransferase	198
2852598282	452	99.34	4	445	2	451	0.0e+00	497.5	COG1797	Cobyrinic acid a,c-diamide synthase	451
2852598283	398	95.49	157	397	3	235	4.7e-86	283.9	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
2852598284	499	75.72	15	301	8	297	4.1e-35	118.4	COG0477	MFS family permease	338
2852598285	497	74.93	14	296	8	294	4.5e-29	98.6	COG0477	MFS family permease	338
2852598286	223	77.23	6	99	19	96	8.7e-03	12.2	COG2154	Pterin-4a-carbinolamine dehydratase	101
2852598288	576	99.24	1	572	3	525	0.0e+00	593.4	COG0442	Prolyl-tRNA synthetase	500
2852598291	177	96.75	6	168	5	153	7.4e-32	106.6	COG0779	Ribosome maturation factor RimP	153
2852598292	344	93.47	141	340	3	188	1.2e-75	249.4	COG0195	Transcription antitermination factor NusA, contains S1 and KH domains	190
2852598294	908	99.11	402	908	2	557	0.0e+00	530.9	COG0532	Translation initiation factor IF-2, a GTPase	509
2852598295	168	95.8	2	121	5	118	1.2e-29	99	COG0858	Ribosome-binding factor A	118
2852598296	342	96.1	26	342	6	325	1.0e-70	234.8	COG0618	nanoRNase/pAp phosphatase, hydrolyzes c-di-AMP and oligoRNAs	332
2852598297	442	95	5	442	16	452	4.2e-84	279.1	COG0534	Na+-driven multidrug efflux pump	455
2852598299	433	93.55	15	191	5	178	3.7e-34	114.1	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2852598300	434	94.09	16	193	4	178	1.5e-31	105.5	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2852598302	188	50.21	2	156	39	158	1.8e-15	50.7	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
2852598303	253	96.23	2	252	5	259	1.9e-64	213.7	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2852598304	88	100	1	86	1	88	3.7e-33	110.4	COG5552	Uncharacterized protein	88
2852598305	181	98.91	1	181	1	182	5.4e-76	250.8	COG4293	Uncharacterized protein	184
2852598307	564	96.81	8	555	16	562	4.3e-129	428.3	COG2936	Predicted acyl esterase	563
2852598309	316	96.96	8	303	2	384	1.3e-26	90.2	COG1409	3',5'-cyclic AMP phosphodiesterase CpdA	301
2852598310	224	95.18	1	224	11	227	8.5e-69	228.2	COG2977	4'-phosphopantetheinyl transferase EntD (siderophore biosynthesis)	228
2852598311	293	87.42	1	289	12	282	5.4e-92	305	COG0130	tRNA U55 pseudouridine synthase TruB, may also work on U342 of tmRNA	271
2852598312	135	45.69	1	125	28	133	5.0e-02	9.4	COG0670	Integral membrane protein, interacts with FtsH	233
2852598313	234	97.4	7	161	3	152	3.1e-51	169.4	COG1321	Mn-dependent transcriptional regulator, DtxR family	154
2852598314	324	99.35	1	322	2	306	3.2e-112	371.1	COG0196	FAD synthase	304
2852598315	89	97.75	1	89	3	89	1.0e-34	115	COG0184	Ribosomal protein S15P/S13E	89
2852598316	271	59.86	5	248	54	220	1.3e-14	51.4	COG0500	SAM-dependent methyltransferase	257
2852598318	753	99.14	12	733	4	691	0.0e+00	968.6	COG1185	Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase)	692
2852598319	448	96.57	11	441	12	433	8.5e-117	386.8	COG0612	Predicted Zn-dependent peptidase	438
2852598320	297	82.63	9	297	35	310	1.4e-54	182.1	COG2367	Beta-lactamase class A	329
2852598321	232	96.68	16	228	3	206	1.2e-18	63.8	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2852598323	371	100	1	371	1	370	0.0e+00	563.2	COG0686	Alanine dehydrogenase	371
2852598324	171	93.04	19	169	4	150	5.0e-36	120.6	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2852598325	907	76.25	835	905	11	71	3.0e-15	50.6	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2852598326	338	90.38	6	330	11	320	1.4e-60	201.6	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852598327	544	98.22	4	386	1	386	4.1e-70	233.5	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2852598328	296	96.27	1	260	6	263	4.3e-41	137.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852598329	210	75.81	113	210	21	114	2.0e-22	38	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
2852598329	210	79.84	4	107	23	121	2.0e-22	39.1	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
2852598332	245	98.88	1	244	3	266	5.1e-76	248.6	COG0289	Dihydrodipicolinate reductase	266
2852598334	151	18.31	1	49	6	44	4.7e-12	5.4	COG0655	Multimeric flavodoxin WrbA	207
2852598334	151	50.23	46	151	75	181	4.7e-12	36.2	COG0655	Multimeric flavodoxin WrbA	207
2852598336	214	88.16	1	213	10	225	7.5e-44	146.4	COG0704	Phosphate uptake regulator	240
2852598337	152	8.24	7	140	455	496	3.0e-03	13.7	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
2852598339	246	97.05	5	246	6	235	2.7e-49	164.2	COG0412	Dienelactone hydrolase	236
2852598340	266	98.53	2	266	5	273	2.8e-120	397.2	COG0207	Thymidylate synthase	268
2852598341	162	98.82	2	160	2	169	1.2e-42	142.1	COG0262	Dihydrofolate reductase	167
2852598342	404	98	1	403	4	396	1.2e-117	389.8	COG3214	Uncharacterized conserved protein YcaQ, contains winged helix DNA-binding domain	400
2852598343	478	93.09	11	459	8	465	1.5e-55	185	COG0531	Amino acid transporter	466
2852598344	303	97.63	4	297	7	294	1.4e-38	129.8	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852598345	259	90.87	17	254	7	225	1.5e-39	132.3	COG2186	DNA-binding transcriptional regulator, FadR family	241
2852598346	250	91.3	1	250	3	254	9.0e-73	241.8	COG1351	Thymidylate synthase ThyX	273
2852598347	300	97.99	8	300	3	295	7.7e-95	313.7	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
2852598348	558	98.72	8	556	8	547	0.0e+00	592.8	COG0595	mRNA degradation ribonuclease J1/J2	555
2852598351	290	95.33	1	290	11	296	5.6e-61	202.8	COG3315	O-Methyltransferase involved in polyketide biosynthesis	297
2852598352	272	99.25	2	269	2	267	3.7e-60	200.2	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852598353	104	96.97	1	95	2	97	6.3e-23	77.1	COG1359	Quinol monooxygenase YgiN	100
2852598355	824	15.19	458	705	24	59	9.9e-03	11	COG1122	Energy-coupling factor transporter ATP-binding protein EcfA2	235
2852598357	169	98.04	8	156	2	151	5.5e-47	155.8	COG1246	N-acetylglutamate synthase or related acetyltransferase, GNAT family	153
2852598358	198	95.88	8	195	8	193	3.1e-48	160.9	COG0558	Phosphatidylglycerophosphate synthase	192
2852598359	162	93.87	4	161	10	162	4.1e-44	146.3	COG1546	Nicotinamide mononucleotide (NMN) deamidase PncC	162
2852598360	108	58.46	8	102	2	77	2.3e-11	41.2	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2852598361	270	98.67	2	246	1	223	9.0e-64	211.5	COG1842	Phage shock protein A	225
2852598364	147	92.31	7	133	6	125	4.0e-44	146.1	COG4308	Limonene-1,2-epoxide hydrolase	130
2852598365	390	96.57	1	389	3	396	3.0e-67	224.1	COG1819	UDP:flavonoid glycosyltransferase YjiC, YdhE family	406
2852598369	270	98.71	1	258	2	307	1.3e-61	205	COG0024	Methionine aminopeptidase	255
2852598370	88	47	11	78	47	93	1.5e-04	18.1	COG3636	DNA-binding prophage protein	100
2852598371	374	99.46	1	364	1	365	0.0e+00	514.8	COG0409	Hydrogenase maturation factor	364
2852598372	90	95.12	1	84	1	78	7.9e-29	96	COG0298	Hydrogenase maturation factor	82
2852598373	361	99.41	28	361	3	339	3.7e-104	344.5	COG0309	Hydrogenase maturation factor	339
2852598374	226	96.05	31	206	7	176	8.5e-41	136.1	COG0279	Phosphoheptose isomerase	176
2852598377	757	99.07	7	756	2	746	0.0e+00	833.7	COG0068	Hydrogenase maturation factor HypF (carbamoyltransferase)	750
2852598378	84	91.46	1	83	1	75	6.8e-19	64.2	COG0298	Hydrogenase maturation factor	82
2852598379	121	70.62	1	116	41	153	9.8e-13	45	COG0680	Ni,Fe-hydrogenase maturation factor	160
2852598384	296	80.65	92	175	11	85	1.9e-19	65.3	COG0694	Fe-S cluster biogenesis protein NfuA, 4Fe-4S-binding domain	93
2852598384	296	96.26	190	292	4	106	7.6e-09	31.5	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
2852598385	598	98.05	19	589	6	559	1.4e-77	250.8	COG0374	Ni,Fe-hydrogenase I large subunit	545
2852598386	351	76.34	2	329	44	314	7.1e-55	182.2	COG1740	Ni,Fe-hydrogenase I small subunit	355
2852598387	197	94.44	2	192	9	195	6.9e-64	211.4	COG0378	Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase	202
2852598388	106	93.91	1	106	5	112	8.8e-26	86.8	COG0375	Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)	115
2852598389	293	89.67	6	278	24	240	1.1e-38	130	COG1376	Lipoprotein-anchoring transpeptidase ErfK/SrfK	232
2852598390	350	100	1	283	1	291	0.0e+00	522.4	COG0468	RecA/RadA recombinase	279
2852598391	181	93.02	8	180	12	171	1.7e-42	141.7	COG2137	SOS response regulatory protein OraA/RecX, interacts with RecA	174
2852598392	294	92.11	44	270	18	227	1.3e-54	181.9	COG0765	ABC-type amino acid transport system, permease component	222
2852598393	226	90.35	2	226	21	226	2.8e-54	180.7	COG0765	ABC-type amino acid transport system, permease component	222
2852598394	270	86.22	3	266	32	275	7.3e-53	176.1	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2852598395	250	99.17	8	248	2	241	5.9e-111	365.9	COG1126	ABC-type polar amino acid transport system, ATPase component	240
2852598396	509	98.64	18	465	3	437	0.0e+00	514	COG0621	tRNA A37 methylthiotransferase MiaB	437
2852598397	202	55.22	141	187	25	61	7.7e-02	9.6	COG3114	Heme exporter protein D	67
2852598399	289	75.08	36	284	66	291	1.9e-09	31.4	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2852598401	301	94.81	1	300	6	297	1.2e-99	329.7	COG0324	tRNA A37 N6-isopentenylltransferase MiaA	308
2852598402	286	99.26	1	278	2	270	2.0e-70	233.5	COG0253	Diaminopimelate epimerase	272
2852598403	470	99.03	45	469	3	410	0.0e+00	517.6	COG2262	50S ribosomal subunit-associated GTPase HflX	411
2852598404	565	99.38	2	560	3	480	0.0e+00	442.5	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
2852598406	79	82.09	1	74	5	59	1.3e-07	28	COG3237	Uncharacterized conserved protein YjbJ, UPF0337 family	67
2852598408	762	88.15	33	745	96	809	0.0e+00	477.7	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2852598409	386	96.99	7	386	7	393	2.5e-119	395.4	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852598410	661	98.3	13	653	10	586	1.7e-66	215.9	COG5479	Uncharacterized conserved protein, contains LGFP repeats	556
2852598411	236	98.52	23	236	3	202	1.5e-70	233.3	COG1974	SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase)	201
2852598413	154	96.79	1	153	1	151	4.7e-62	205.1	COG1327	Transcriptional regulator NrdR, contains Zn-ribbon and ATP-cone domains	156
2852598414	228	28.08	125	227	207	288	7.6e-44	38.2	COG0384	Predicted epimerase YddE/YHI9, PhzF superfamily	291
2852598414	228	50.34	1	152	2	148	7.6e-44	107.7	COG0384	Predicted epimerase YddE/YHI9, PhzF superfamily	291
2852598415	340	97.29	18	295	7	293	2.8e-51	171.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852598416	322	90.2	28	279	17	237	6.1e-06	19.4	COG1938	Predicted ATP-dependent carboligase, ATP-grasp superfamily	244
2852598418	471	99.78	3	456	2	455	0.0e+00	456.9	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
2852598420	229	87.01	1	159	1	134	1.9e-53	176.3	COG1321	Mn-dependent transcriptional regulator, DtxR family	154
2852598421	319	97.65	13	319	8	340	6.4e-114	375.4	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
2852598424	331	95.38	5	303	11	299	6.7e-67	222.2	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
2852598426	118	93.91	3	118	3	110	4.3e-37	123.2	COG3502	Uncharacterized conserved protein, DUF952 family	115
2852598427	121	93.38	1	121	8	134	4.3e-19	65.3	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
2852598429	270	60.93	6	266	18	226	2.1e-34	115.3	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852598430	364	46.59	154	359	47	176	8.9e-04	14	COG0500	SAM-dependent methyltransferase	257
2852598432	504	92.08	110	504	28	341	2.1e-123	405.2	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
2852598433	269	25.48	177	268	223	301	8.9e-34	22.5	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
2852598433	269	52.9	16	187	7	170	8.9e-34	95.3	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
2852598434	277	87.64	12	272	32	258	2.3e-65	217	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
2852598438	154	93.96	1	151	9	148	6.2e-52	171.7	COG0756	dUTPase	148
2852598440	232	86.1	3	232	25	278	1.6e-09	34.5	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852598441	123	12.83	9	123	52	138	9.1e-03	11	COG1200	RecG-like helicase	677
2852598443	476	46.21	262	463	13	189	1.4e-34	8.7	COG0477	MFS family permease	338
2852598443	476	87.47	9	315	5	339	1.4e-34	109.9	COG0477	MFS family permease	338
2852598444	221	98.21	1	220	2	221	6.3e-51	169.6	COG0569	Trk K+ transport system, NAD-binding component	225
2852598445	224	95.98	1	214	2	216	4.5e-46	153.6	COG0569	Trk K+ transport system, NAD-binding component	225
2852598446	664	90.85	24	503	35	481	1.0e-33	113	COG0531	Amino acid transporter	466
2852598447	408	35.55	16	186	15	169	3.0e-77	112.2	COG2265	tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family	432
2852598447	408	42.89	196	402	250	436	3.0e-77	143.1	COG2265	tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family	432
2852598448	702	97.21	9	515	8	494	0.0e+00	716.1	COG0753	Catalase	496
2852598452	860	32.88	272	571	189	309	6.4e-06	18.2	COG0457	Tetratricopeptide (TPR) repeat	291
2852598452	860	88.75	781	859	9	79	4.6e-18	59.2	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2852598453	158	94.3	8	155	4	152	4.1e-26	88.4	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2852598454	154	96.73	2	154	5	152	6.2e-10	33.5	COG4276	Ligand-binding SRPBCC domain	153
2852598455	428	97.2	17	405	6	387	1.3e-110	366.1	COG3004	Na+/H+ antiporter NhaA	390
2852598456	637	98.88	1	624	4	623	0.0e+00	799.4	COG1154	Deoxyxylulose-5-phosphate synthase	627
2852598457	298	96.61	11	297	6	290	1.5e-26	89.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852598458	423	99.17	30	412	3	361	7.8e-106	350.7	COG0349	Ribonuclease D	361
2852598460	371	97.73	23	371	5	349	1.7e-122	405.3	COG0407	Uroporphyrinogen-III decarboxylase	352
2852598461	449	99.33	1	444	2	446	9.7e-106	350.7	COG1232	Protoporphyrinogen oxidase	444
2852598462	230	99.13	5	230	2	229	3.1e-78	259.1	COG3253	Chlorite dismutase	230
2852598463	548	98.87	40	548	3	439	3.2e-127	421.6	COG0281	Malic enzyme	432
2852598465	138	90.07	7	138	4	130	5.2e-58	191.2	COG0229	Peptide methionine sulfoxide reductase MsrB	140
2852598466	2386	17.52	1424	1457	10	33	5.0e-06	6.8	COG4319	Ketosteroid isomerase homolog	137
2852598466	2386	30.74	199	305	81	155	6.5e-37	6.5	COG2114	Adenylate cyclase, class 3	227
2852598466	2386	36.5	1299	1371	19	68	5.0e-06	7.4	COG4319	Ketosteroid isomerase homolog	137
2852598466	2386	77.87	2	201	49	238	6.5e-37	123.9	COG2114	Adenylate cyclase, class 3	227
2852598469	521	90.85	62	496	9	276	1.5e-22	75.8	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852598470	257	90.91	31	256	5	204	1.8e-37	125.4	COG1985	Pyrimidine reductase, riboflavin biosynthesis	218
2852598471	349	26.61	226	344	266	364	9.7e-65	57.6	COG1485	Predicted ATPase	367
2852598471	349	59.68	6	241	7	228	9.7e-65	156.8	COG1485	Predicted ATPase	367
2852598472	176	80.95	4	176	32	184	7.8e-17	58.1	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2852598475	197	97.62	34	197	4	167	8.5e-42	139.9	COG0350	O6-methylguanine-DNA--protein-cysteine methyltransferase	168
2852598476	158	88.71	2	158	16	180	6.8e-32	107.1	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2852598479	118	31.69	4	118	214	316	6.1e-22	74.5	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
2852598482	52	23.81	1	51	48	77	4.0e-03	13.6	COG5349	Uncharacterized conserved protein, DUF983 family	126
2852598495	330	12.5	2	35	24	50	1.5e-08	17.7	COG0778	Nitroreductase	207
2852598495	330	33.33	141	324	140	211	1.5e-08	9.5	COG0778	Nitroreductase	207
2852598496	179	74.87	10	159	14	153	2.2e-06	24.2	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2852598497	271	94.97	1	142	8	158	1.0e-19	68	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2852598499	294	94.34	157	294	8	157	4.4e-43	60.8	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2852598499	294	96.86	1	150	5	158	4.4e-43	89.6	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2852598500	232	97.16	18	225	2	206	1.0e-60	201.3	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2852598501	288	94.97	147	286	7	157	2.3e-18	10.9	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2852598501	288	95.6	5	144	6	157	2.3e-18	55.9	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2852598503	499	72.43	325	493	3	136	2.0e-09	33.3	COG0563	Adenylate kinase or related kinase	178
2852598503	499	93.18	8	324	21	334	5.4e-97	320.9	COG2187	Aminoglycoside phosphotransferase family enzyme	337
2852598504	277	77.36	2	119	36	158	4.5e-26	34.8	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2852598504	277	96.23	121	265	5	157	4.5e-26	59.5	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2852598507	82	68.38	1	78	37	116	1.4e-11	40.9	COG3462	Uncharacterized membrane protein	117
2852598508	125	35.74	1	120	26	134	4.0e-25	85.6	COG3118	Negative regulator of GroEL, contains thioredoxin-like and TPR-like domains	304
2852598509	459	43.86	253	347	10	59	2.8e-29	8	COG0607	Rhodanese-related sulfurtransferase	110
2852598509	459	88.6	358	457	6	106	2.8e-29	88.6	COG0607	Rhodanese-related sulfurtransferase	110
2852598509	459	89.23	1	252	19	250	8.8e-37	122.7	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2852598510	290	95.37	1	249	7	253	9.9e-53	175.8	COG0730	Uncharacterized membrane protein YfcA	258
2852598511	89	92.13	1	89	6	87	2.0e-26	88.8	COG1937	DNA-binding transcriptional regulator, FrmR family	89
2852598514	774	82.76	3	615	123	727	0.0e+00	550.7	COG2217	Cation transport ATPase	713
2852598515	868	93.06	22	842	52	950	0.0e+00	565.9	COG0474	Magnesium-transporting ATPase (P-type)	917
2852598516	756	99.62	3	749	3	786	0.0e+00	647.6	COG0574	Phosphoenolpyruvate synthase/pyruvate phosphate dikinase	740
2852598517	329	97.1	8	315	2	302	7.5e-82	271.1	COG1105	Fructose-1-phosphate kinase or kinase (PfkB)	310
2852598518	1318	21.27	279	337	80	126	1.6e-43	4.2	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
2852598518	1318	97.29	11	252	2	216	1.6e-43	138.5	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
2852598518	1318	98.97	515	1318	5	769	0.0e+00	735.7	COG1554	Trehalose and maltose hydrolase (possible phosphorylase)	772
2852598519	293	94.34	158	293	7	156	2.1e-30	45.7	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2852598519	293	94.97	7	149	7	157	2.1e-30	61	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2852598522	299	95.6	6	156	6	157	7.3e-45	80.8	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2852598522	299	96.23	160	298	4	156	7.3e-45	75.2	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2852598523	301	99.68	1	301	1	311	3.2e-118	390.9	COG0549	Carbamate kinase	312
2852598524	334	99.04	2	334	3	310	1.7e-126	418.2	COG0078	Ornithine carbamoyltransferase	310
2852598525	419	99.26	4	417	4	407	0.0e+00	439.5	COG2235	Arginine deiminase	409
2852598526	492	92.68	17	488	13	468	8.6e-68	225.1	COG0531	Amino acid transporter	466
2852598527	331	13.43	4	37	22	50	1.2e-07	18.2	COG0778	Nitroreductase	207
2852598527	331	37.5	167	331	131	211	1.2e-07	4.6	COG0778	Nitroreductase	207
2852598528	196	54.84	17	64	20	53	1.3e-03	13.4	COG4459	Periplasmic nitrate reductase system, NapE component	62
2852598530	331	85.65	5	331	28	212	9.2e-10	33.8	COG0778	Nitroreductase	207
2852598532	76	25.93	6	72	134	182	1.9e-02	10.8	COG3506	Regulation of enolase protein 1 (function unknown), concanavalin A-like superfamily	189
2852598533	149	93.75	3	149	4	153	3.3e-19	66	COG0680	Ni,Fe-hydrogenase maturation factor	160
2852598534	430	96.26	5	430	4	440	7.8e-92	305	COG3259	Coenzyme F420-reducing hydrogenase, alpha subunit	441
2852598535	252	91.57	1	241	4	231	7.0e-46	153	COG1941	Coenzyme F420-reducing hydrogenase, gamma subunit	247
2852598536	285	96.5	10	278	8	255	4.4e-47	156.8	COG0543	NAD(P)H-flavin reductase	252
2852598537	365	66.13	217	364	22	103	1.2e-07	26.8	COG1145	Ferredoxin	99
2852598538	144	75.3	1	143	7	131	7.8e-11	39	COG3467	Nitroimidazol reductase NimA or a related FMN-containing flavoprotein, pyridoxamine 5'-phosphate oxidase superfamily	166
2852598541	681	14.78	112	173	111	140	1.3e-12	18	COG0461	Orotate phosphoribosyltransferase	201
2852598541	681	33	14	99	57	123	1.3e-12	24.1	COG0461	Orotate phosphoribosyltransferase	201
2852598541	681	97.78	224	663	9	405	0.0e+00	460.8	COG2312	Erythromycin esterase homolog	405
2852598542	293	85.58	12	289	47	325	6.0e-29	97.1	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
2852598543	305	84.66	1	294	49	324	9.7e-50	165.8	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
2852598545	573	93.33	138	571	26	375	7.3e-66	219	COG4585	Signal transduction histidine kinase	365
2852598546	255	96.23	6	140	5	157	1.6e-14	51.7	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2852598548	136	27.51	2	126	40	124	2.0e-05	20.2	COG4965	Flp pilus assembly protein TadB	309
2852598550	289	92.98	10	280	16	240	4.2e-53	177.4	COG1376	Lipoprotein-anchoring transpeptidase ErfK/SrfK	232
2852598551	236	49.69	12	195	17	178	1.6e-07	27.4	COG2203	GAF domain	175
2852598552	165	97.62	1	165	3	166	6.0e-53	175.7	COG4762	Uncharacterized protein, UPF0548 family	168
2852598553	290	95.31	10	289	7	311	8.6e-85	274.9	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2852598554	208	78.01	77	205	25	134	1.0e-07	27.7	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
2852598556	684	99.33	39	674	2	591	0.0e+00	846.6	COG0441	Threonyl-tRNA synthetase	589
2852598557	185	94.33	44	183	5	137	1.1e-37	125.4	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
2852598558	227	94.85	21	213	4	187	1.4e-30	103.2	COG0558	Phosphatidylglycerophosphate synthase	192
2852598559	301	92.21	4	299	18	301	1.9e-70	233.7	COG1560	Lauroyl/myristoyl acyltransferase	308
2852598560	394	99.27	1	367	1	406	4.1e-53	177.9	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2852598561	348	79.65	164	334	17	153	1.4e-15	54.4	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2852598562	305	99.32	10	305	3	296	0.0e+00	509.9	COG0214	Pyridoxal biosynthesis lyase PdxS	296
2852598563	279	96.9	1	278	8	288	1.9e-102	338.8	COG1946	Acyl-CoA thioesterase	289
2852598564	194	96.91	4	194	2	189	1.1e-73	243.6	COG0311	Glutamine amidotransferase PdxT (pyridoxal biosynthesis)	194
2852598565	224	87.31	1	221	7	240	1.0e-44	149.6	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852598567	251	99.18	1	242	1	241	1.6e-94	312.4	COG0217	Transcriptional and/or translational regulatory protein YebC/TACO1	241
2852598568	142	91.6	2	140	12	131	8.9e-20	66.8	COG5485	Predicted ester cyclase	131
2852598570	655	15.43	530	655	680	804	3.3e-73	29.1	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2852598570	655	64.32	1	521	45	565	3.3e-73	212.7	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2852598571	278	98.31	1	277	5	294	2.0e-24	83.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852598572	198	81.34	1	193	13	182	5.8e-16	56.3	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852598574	188	96.89	1	164	1	156	2.5e-58	192.6	COG0817	Holliday junction resolvasome RuvABC endonuclease subunit	160
2852598575	195	99	1	193	1	199	1.3e-57	191.1	COG0632	Holliday junction resolvasome RuvABC DNA-binding subunit	201
2852598576	355	99.1	13	344	2	330	0.0e+00	484.5	COG2255	Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit	332
2852598577	128	96.69	1	125	4	120	2.4e-27	91.9	COG3759	Uncharacterized membrane protein	121
2852598578	1169	71.6	648	725	20	77	3.9e-03	12.8	COG0236	Acyl carrier protein	80
2852598578	1169	99.18	44	646	3	610	6.3e-122	403.5	COG1022	Long-chain acyl-CoA synthetase (AMP-forming)	613
2852598578	1169	99.74	774	1169	1	382	0.0e+00	451.3	COG3320	Thioester reductase domain of alpha aminoadipate reductase Lys2 and NRPSs	382
2852598580	1093	80.33	3	192	47	242	4.9e-44	145.5	COG2114	Adenylate cyclase, class 3	227
2852598580	1093	83.75	1012	1090	11	77	5.7e-22	72.6	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2852598580	1093	96.62	212	617	6	405	0.0e+00	505.4	COG3903	Predicted ATPase	414
2852598582	150	57.89	9	147	22	98	1.5e-12	44.1	COG1846	DNA-binding transcriptional regulator, MarR family	126
2852598583	281	96.61	6	274	9	293	4.2e-24	82.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852598584	477	98.75	4	477	2	474	0.0e+00	500.6	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2852598585	446	97.53	3	446	10	444	0.0e+00	533.9	COG0160	4-aminobutyrate aminotransferase or related aminotransferase	447
2852598586	136	97.95	1	131	3	145	9.3e-08	29.6	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2852598587	120	80.41	1	101	9	86	1.7e-23	79.1	COG1862	Preprotein translocase subunit YajC	97
2852598588	604	22.18	7	137	7	122	0.0e+00	71.4	COG0342	Preprotein translocase subunit SecD	506
2852598588	604	63.86	226	582	187	520	0.0e+00	403	COG0342	Preprotein translocase subunit SecD	506
2852598589	404	98.38	26	349	2	304	1.2e-88	293.7	COG0341	Preprotein translocase subunit SecF	305
2852598590	551	97.58	1	549	9	572	4.4e-35	117.9	COG0747	ABC-type transport system, periplasmic component	556
2852598591	174	96.09	1	174	4	175	4.0e-47	156.4	COG0503	Adenine/guanine phosphoribosyltransferase or related PRPP-binding protein	179
2852598592	785	99.45	51	781	5	724	0.0e+00	960.9	COG0317	(p)ppGpp synthase/hydrolase, HD superfamily	701
2852598594	97	23.9	13	83	127	175	7.2e-03	12.3	COG0062	NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate epimerase domain	203
2852598595	335	98.09	168	335	2	155	6.2e-36	120.1	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
2852598596	292	96.82	126	292	2	153	7.3e-38	126	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
2852598597	227	92.69	2	227	17	257	1.1e-49	165.8	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2852598598	421	99.07	1	419	3	430	0.0e+00	434.6	COG0124	Histidyl-tRNA synthetase	429
2852598600	241	55.83	6	205	8	189	2.2e-14	49.9	COG2203	GAF domain	175
2852598603	209	96.13	1	177	5	178	8.7e-37	122.9	COG3038	Cytochrome b561	181
2852598604	351	59.08	55	341	61	356	4.2e-33	108.5	COG0753	Catalase	496
2852598605	553	89.96	37	493	32	434	2.0e-23	79	COG1457	Purine-cytosine permease or related protein	442
2852598607	296	97.63	11	292	7	294	4.1e-33	111.7	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852598608	195	82.78	1	193	10	182	7.5e-14	49.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852598609	408	94.15	3	393	4	373	1.4e-52	175.9	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2852598610	211	62.77	2	142	9	94	1.1e-15	53.8	COG1695	DNA-binding transcriptional regulator, PadR family	138
2852598611	338	87.54	31	320	6	265	3.4e-73	242.9	COG1533	DNA repair photolyase	297
2852598613	226	75.12	9	215	8	164	9.8e-18	61.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852598614	417	97.49	2	401	7	395	4.1e-52	173.8	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852598615	375	97.24	1	372	1	388	1.5e-54	182.1	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852598616	407	80.92	33	393	56	301	3.0e-15	52.9	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
2852598617	210	82.3	1	207	11	182	6.8e-16	56.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852598618	293	96.55	8	284	8	287	1.1e-25	81.5	COG1946	Acyl-CoA thioesterase	289
2852598619	274	98.88	5	272	3	267	6.9e-61	202.6	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852598621	548	95.41	2	547	23	583	1.4e-116	386.9	COG4805	Uncharacterized conserved protein, DUF885 familyt	588
2852598622	295	97.64	1	295	5	293	1.2e-99	329.9	COG2321	Predicted metalloprotease	295
2852598623	501	98.58	7	501	3	489	3.3e-127	422.1	COG2272	Carboxylesterase type B	491
2852598624	165	95.21	17	161	6	144	6.9e-05	19.2	COG3427	Carbon monoxide dehydrogenase subunit G	146
2852598625	295	97.41	3	295	2	302	9.8e-60	198.9	COG1893	Ketopantoate reductase	307
2852598626	589	99.49	2	586	2	584	0.0e+00	786.5	COG0173	Aspartyl-tRNA synthetase	585
2852598627	862	91.82	543	858	24	315	2.6e-70	233.5	COG0657	Acetyl esterase/lipase	312
2852598627	862	95.74	2	486	8	434	2.7e-112	372.1	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
2852598629	296	93	8	296	19	337	4.5e-44	147.2	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852598631	393	99.49	6	393	2	393	9.0e-120	396.9	COG0183	Acetyl-CoA acetyltransferase	392
2852598632	156	82.5	9	134	10	108	1.7e-23	78.7	COG1733	DNA-binding transcriptional regulator, HxlR family	120
2852598633	158	57.07	14	145	38	146	6.8e-20	67.5	COG4420	Uncharacterized membrane protein	191
2852598634	125	97.58	3	125	1	121	1.6e-39	131	COG3801	Uncharacterized protein	124
2852598635	1105	100	292	1103	1	808	0.0e+00	1378.3	COG4196	Uncharacterized conserved protein, DUF2126 family	808
2852598636	883	97.54	28	525	4	479	0.0e+00	545.4	COG2308	Uncharacterized conserved protein, circularly permuted ATPgrasp superfamily	488
2852598636	883	99.04	540	870	2	311	2.2e-88	293	COG2307	Uncharacterized conserved protein, Alpha-E superfamily	313
2852598637	307	91.42	14	305	13	321	2.1e-59	198.2	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
2852598638	341	96.56	1	341	1	337	0.0e+00	498.6	COG4307	Uncharacterized protein	349
2852598639	250	88.13	1	249	13	257	3.3e-16	55.8	COG1082	Sugar phosphate isomerase/epimerase	274
2852598642	131	61.24	11	122	43	121	3.6e-14	49	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
2852598643	442	96.8	16	442	12	434	0.0e+00	580.4	COG2256	Replication-associated recombination protein RarA (DNA-dependent ATPase)	436
2852598644	120	79.66	8	111	18	111	4.5e-14	49.2	COG0640	DNA-binding transcriptional regulator, ArsR family	110
2852598645	157	97.45	8	156	4	156	9.1e-23	77.3	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
2852598646	132	81.51	3	125	4	122	9.2e-12	42.9	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2852598647	102	96.34	4	89	2	80	1.3e-13	47.3	COG2261	Uncharacterized membrane protein YeaQ/YmgE, transglycosylase-associated protein family	82
2852598648	207	40.57	8	98	25	67	2.0e-04	9.9	COG2329	Heme-degrading monooxygenase HmoA and related ABM domain proteins	105
2852598648	207	58.49	105	199	9	70	2.0e-04	6.2	COG2329	Heme-degrading monooxygenase HmoA and related ABM domain proteins	105
2852598649	136	96.35	4	135	6	137	1.2e-37	125.3	COG0432	Thiamin phosphate synthase YjbQ, UPF0047 family	137
2852598650	895	98.64	1	894	7	876	0.0e+00	1023.5	COG0013	Alanyl-tRNA synthetase	879
2852598651	180	97.87	19	162	2	139	1.5e-39	131.7	COG0816	RNase H-fold protein, predicted Holliday junction resolvase in Firmicutes and mycoplasms, involved in anti-termination at Rho-dependent terminators	141
2852598652	416	98.84	38	412	3	342	3.6e-92	305.6	COG1559	Cell division protein YceG, involved in septum cleavage	342
2852598653	267	96.48	5	267	7	280	6.2e-71	235.1	COG0169	Shikimate 5-dehydrogenase	283
2852598654	260	55.1	3	251	17	205	2.5e-28	95.2	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852598655	295	94.52	2	289	12	287	1.2e-79	263.8	COG5006	Threonine/homoserine efflux transporter RhtA	292
2852598656	143	56.25	1	143	98	241	4.2e-17	59.4	COG1989	Prepilin signal peptidase PulO (type II secretory pathway) or related peptidase	254
2852598657	127	55.36	3	111	4	65	3.3e-06	23.5	COG4538	Uncharacterized protein	112
2852598660	200	84.21	2	199	9	184	1.5e-26	90.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852598661	405	98.11	1	388	5	367	0.0e+00	453.3	COG0082	Chorismate synthase	369
2852598662	216	96.51	1	172	3	168	7.4e-49	162.5	COG0703	Shikimate kinase	172
2852598663	361	98.33	2	359	4	357	5.1e-118	390.9	COG0337	3-dehydroquinate synthetase	360
2852598664	145	95.21	4	145	2	140	1.4e-61	202.9	COG0757	3-dehydroquinate dehydratase	146
2852598665	187	26.11	1	155	18	117	9.5e-04	15.4	COG0477	MFS family permease	338
2852598666	371	96.92	1	371	11	388	4.3e-103	342	COG0006	Xaa-Pro aminopeptidase	384
2852598667	187	96.95	1	129	5	131	3.7e-47	155.7	COG0231	Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)	131
2852598668	159	89.54	2	145	11	147	7.7e-39	129.3	COG0781	Transcription termination factor NusB	151
2852598671	246	94.14	8	241	11	235	3.5e-50	167.1	COG2188	DNA-binding transcriptional regulator, GntR family	236
2852598672	75	89.04	10	72	2	66	4.0e-12	40.2	COG1146	NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit	68
2852598673	476	89.85	1	356	6	306	7.1e-40	133.4	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2852598674	287	97.67	23	283	4	255	3.5e-68	226.3	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2852598675	248	96.41	8	248	4	245	2.0e-81	269.7	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2852598676	895	49.58	611	799	85	259	1.1e-12	26.1	COG1413	HEAT repeat	335
2852598676	895	58.36	679	895	52	257	1.1e-12	26.8	COG1413	HEAT repeat	335
2852598676	895	99.12	8	560	3	563	1.1e-105	350.3	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
2852598679	973	24.32	851	972	101	198	2.7e-80	32.7	COG3391	DNA-binding beta-propeller fold protein YncE	381
2852598679	973	25.56	722	878	150	252	2.7e-80	6	COG3391	DNA-binding beta-propeller fold protein YncE	381
2852598679	973	26.05	623	724	160	264	2.7e-80	32.7	COG3391	DNA-binding beta-propeller fold protein YncE	381
2852598679	973	34.99	201	356	121	261	2.7e-80	69.9	COG3391	DNA-binding beta-propeller fold protein YncE	381
2852598679	973	44.42	255	445	80	258	2.7e-80	107	COG3391	DNA-binding beta-propeller fold protein YncE	381
2852598679	973	67.25	344	625	67	337	2.7e-80	85.2	COG3391	DNA-binding beta-propeller fold protein YncE	381
2852598681	991	29.53	856	991	81	199	8.2e-51	24.3	COG3391	DNA-binding beta-propeller fold protein YncE	381
2852598681	991	38.46	22	360	105	259	8.2e-51	16.1	COG3391	DNA-binding beta-propeller fold protein YncE	381
2852598681	991	42.18	675	860	131	300	8.2e-51	29.1	COG3391	DNA-binding beta-propeller fold protein YncE	381
2852598681	991	73.2	354	673	28	322	8.2e-51	111.4	COG3391	DNA-binding beta-propeller fold protein YncE	381
2852598682	400	95.17	1	390	4	377	8.2e-53	176.6	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2852598683	401	87.13	2	394	43	394	1.9e-67	224.7	COG1680	CubicO group peptidase, beta-lactamase class C family	390
2852598684	1525	22.08	369	470	123	211	2.8e-118	30.8	COG3391	DNA-binding beta-propeller fold protein YncE	381
2852598684	1525	35.24	1318	1524	61	202	2.8e-118	36.7	COG3391	DNA-binding beta-propeller fold protein YncE	381
2852598684	1525	36.48	951	1094	94	240	2.8e-118	118.8	COG3391	DNA-binding beta-propeller fold protein YncE	381
2852598684	1525	37.97	786	956	26	178	2.8e-118	11.2	COG3391	DNA-binding beta-propeller fold protein YncE	381
2852598684	1525	39.7	1059	1213	67	226	2.8e-118	83.1	COG3391	DNA-binding beta-propeller fold protein YncE	381
2852598684	1525	41.69	457	621	70	237	2.8e-118	106.1	COG3391	DNA-binding beta-propeller fold protein YncE	381
2852598684	1525	45.16	1183	1379	72	253	2.8e-118	69.9	COG3391	DNA-binding beta-propeller fold protein YncE	381
2852598684	1525	60.55	591	900	80	323	2.8e-118	15.7	COG3391	DNA-binding beta-propeller fold protein YncE	381
2852598685	180	94.41	1	175	7	175	7.9e-71	233.7	COG2065	Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase	179
2852598686	314	97.46	1	310	7	313	2.4e-111	368.1	COG0540	Aspartate carbamoyltransferase, catalytic chain	316
2852598687	430	98.61	1	429	1	425	0.0e+00	512.6	COG0044	Dihydroorotase or related cyclic amidohydrolase	430
2852598689	372	98.11	1	372	2	365	0.0e+00	463.5	COG0505	Carbamoylphosphate synthase small subunit	368
2852598690	1112	93.9	571	975	1	385	0.0e+00	253.1	COG0458	Carbamoylphosphate synthase large subunit	400
2852598690	1112	97.8	13	430	1	401	0.0e+00	650.9	COG0458	Carbamoylphosphate synthase large subunit	400
2852598691	272	98.33	3	269	2	237	5.6e-54	179.4	COG0284	Orotidine-5'-phosphate decarboxylase	240
2852598692	105	25.15	1	94	152	233	1.1e-03	14.9	COG3547	Transposase	303
2852598693	142	69.74	1	142	49	184	8.3e-48	159.2	COG0194	Guanylate kinase	191
2852598694	105	97.3	30	104	2	73	2.9e-20	67.9	COG1758	DNA-directed RNA polymerase, subunit K/omega	74
2852598695	417	98.75	2	413	4	399	3.5e-124	411.2	COG0452	Phosphopantothenoylcysteine synthetase/decarboxylase	392
2852598696	402	98.97	1	402	3	387	0.0e+00	589.4	COG0192	S-adenosylmethionine synthetase	388
2852598697	496	98.88	1	455	5	445	3.8e-124	411.9	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
2852598699	318	97.23	1	318	7	322	4.7e-88	291.9	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
2852598700	315	89.94	7	314	31	316	5.2e-82	272.4	COG0657	Acetyl esterase/lipase	312
2852598701	226	98.11	7	220	3	210	2.2e-57	190.7	COG3714	Uncharacterized membrane protein YhhN	212
2852598702	664	14.31	13	147	6	110	0.0e+00	75.6	COG1198	Primosomal protein N' (replication factor Y) - superfamily II helicase	730
2852598702	664	72.89	121	663	200	734	0.0e+00	380.9	COG1198	Primosomal protein N' (replication factor Y) - superfamily II helicase	730
2852598704	178	91.35	1	178	4	172	9.3e-49	161.9	COG1704	Uncharacterized conserved protein	185
2852598705	309	99.03	1	306	2	306	2.4e-102	338.8	COG0223	Methionyl-tRNA formyltransferase	307
2852598706	456	98.88	106	454	1	354	8.4e-79	261.8	COG0144	16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family	355
2852598707	225	98.18	1	219	2	217	3.3e-82	271.3	COG0036	Pentose-5-phosphate-3-epimerase	220
2852598708	333	87.67	1	144	7	134	3.8e-49	162.1	COG0117	Pyrimidine deaminase domain of riboflavin biosynthesis protein RibD	146
2852598708	333	98.18	145	333	2	217	3.1e-48	156.7	COG1985	Pyrimidine reductase, riboflavin biosynthesis	218
2852598709	144	88.55	2	131	16	131	4.9e-07	26.3	COG5485	Predicted ester cyclase	131
2852598710	330	93.81	3	223	3	214	7.2e-72	237.6	COG1136	ABC-type lipoprotein export system, ATPase component	226
2852598711	349	26.47	13	145	1	135	9.3e-18	8.4	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
2852598711	349	28.82	164	348	361	507	9.3e-18	56.4	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
2852598712	187	95.41	6	186	6	192	7.8e-41	136.4	COG0693	Putative intracellular protease/amidase	188
2852598714	537	49.61	280	517	6	195	3.7e-34	8.4	COG0477	MFS family permease	338
2852598714	537	80.16	18	315	8	314	3.7e-34	108.5	COG0477	MFS family permease	338
2852598716	197	94.63	1	197	1	194	1.5e-70	232.9	COG0307	Riboflavin synthase alpha chain	204
2852598719	423	98.52	2	207	4	203	2.3e-84	278.1	COG0108	3,4-dihydroxy-2-butanone 4-phosphate synthase	203
2852598720	158	94.08	9	155	9	151	1.9e-50	167	COG0054	6,7-dimethyl-8-ribityllumazine synthase (Riboflavin synthase beta chain)	152
2852598722	158	60.43	6	142	44	156	6.4e-14	48.8	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2852598723	646	97.8	52	644	12	544	0.0e+00	596.7	COG0405	Gamma-glutamyltranspeptidase	539
2852598724	660	99.67	3	638	3	598	0.0e+00	754.7	COG0322	Excinuclease UvrABC, nuclease subunit	581
2852598725	303	99.3	20	303	2	285	1.4e-115	382	COG1660	RNase adaptor protein for sRNA GlmZ degradation, contains a P-loop ATPase domain	286
2852598726	341	97.82	1	308	6	319	2.8e-93	309	COG0391	Archaeal 2-phospho-L-lactate transferase/Bacterial gluconeogenesis factor, CofD/UPF0052 family	323
2852598727	327	99.03	1	311	2	306	6.7e-99	327.6	COG1481	DNA-binding transcriptional regulator WhiA, involved in cell division	308
2852598730	878	77.87	2	172	54	243	5.4e-33	111.1	COG2114	Adenylate cyclase, class 3	227
2852598730	878	92.03	191	593	9	389	1.1e-85	283.6	COG3903	Predicted ATPase	414
2852598731	885	93	188	600	3	387	1.9e-86	286.4	COG3903	Predicted ATPase	414
2852598732	875	91.06	188	586	3	379	1.2e-85	283.3	COG3903	Predicted ATPase	414
2852598733	236	82.33	2	236	46	278	1.3e-30	103.1	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2852598734	340	99.1	2	340	1	332	0.0e+00	470	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
2852598735	403	97.24	3	403	8	394	0.0e+00	502.7	COG0126	3-phosphoglycerate kinase	395
2852598736	261	96.83	2	257	2	245	6.9e-91	300.4	COG0149	Triosephosphate isomerase	251
2852598737	77	79.57	1	77	2	75	6.5e-19	64.1	COG1314	Preprotein translocase subunit SecG	86
2852598742	931	99.56	20	931	5	913	0.0e+00	1168	COG2352	Phosphoenolpyruvate carboxylase	910
2852598743	124	26.49	10	123	167	264	1.4e-06	24.1	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852598744	245	98.33	4	245	3	238	3.6e-63	209.6	COG0363	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase	238
2852598745	308	94.59	19	308	2	298	1.7e-100	332.7	COG3429	Glucose-6-phosphate dehydrogenase assembly protein OpcA, contains a peptidoglycan-binding domain	314
2852598746	519	98.77	27	519	6	485	0.0e+00	621.7	COG0364	Glucose-6-phosphate 1-dehydrogenase	483
2852598747	372	99.34	12	365	2	303	1.7e-95	316.7	COG0176	Transaldolase	239
2852598748	696	99.55	18	695	3	662	0.0e+00	899.7	COG0021	Transketolase	663
2852598749	310	93.16	7	307	18	303	5.4e-111	367.2	COG0109	Polyprenyltransferase (heme O synthase)	304
2852598750	323	100	1	323	1	331	3.3e-87	289.5	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2852598752	318	94.43	9	317	14	335	1.2e-66	221	COG1612	Heme A synthase	323
2852598753	180	90.91	1	180	14	203	1.9e-11	41.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852598754	518	49.61	253	506	3	192	1.6e-30	14.6	COG0477	MFS family permease	338
2852598754	518	83.29	2	299	6	324	1.6e-30	92.7	COG0477	MFS family permease	338
2852598757	465	14.5	317	461	400	467	3.0e-35	18.6	COG0277	FAD/FMN-containing dehydrogenase	459
2852598757	465	40.94	14	293	24	215	3.0e-35	99.1	COG0277	FAD/FMN-containing dehydrogenase	459
2852598758	493	93.9	20	488	7	468	2.8e-57	190.7	COG0531	Amino acid transporter	466
2852598759	257	67.24	35	257	92	288	2.2e-10	36.6	COG0842	ABC-type multidrug transport system, permease component	286
2852598760	310	98.69	6	306	5	306	4.2e-78	259.3	COG1131	ABC-type multidrug transport system, ATPase component	293
2852598762	249	96.8	10	229	5	216	8.7e-70	231.6	COG2345	Predicted transcriptional regulator, ArsR family	218
2852598763	481	100	48	479	1	434	0.0e+00	878.8	COG0719	Fe-S cluster assembly scaffold protein SufB	412
2852598764	389	68.89	51	382	134	432	9.5e-58	192.5	COG0719	Fe-S cluster assembly scaffold protein SufB	412
2852598765	255	98.41	1	255	1	248	8.3e-107	352.6	COG0396	Fe-S cluster assembly ATPase SufC	251
2852598766	418	99.02	9	418	3	407	0.0e+00	514.5	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
2852598767	156	94.04	1	152	3	144	1.6e-46	154.4	COG0822	NifU homolog involved in Fe-S cluster formation	150
2852598768	115	91.15	1	114	9	111	5.3e-35	116.3	COG2151	Metal-sulfur cluster biosynthetic enzyme	111
2852598770	292	70.37	151	280	41	154	2.7e-11	39.4	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2852598770	292	82.71	8	140	22	131	2.2e-17	59.3	COG1846	DNA-binding transcriptional regulator, MarR family	126
2852598772	238	92.49	12	224	12	208	6.7e-25	84.7	COG0655	Multimeric flavodoxin WrbA	207
2852598773	209	93.01	6	209	8	180	1.5e-36	122.3	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2852598774	80	19.09	6	62	1	46	1.9e-05	20.5	COG5660	Predicted anti-sigma-YlaC factor YlaD, contains Zn-finger domain	238
2852598775	121	37.38	1	120	27	140	1.6e-21	73.8	COG3118	Negative regulator of GroEL, contains thioredoxin-like and TPR-like domains	304
2852598776	269	96.6	2	265	10	265	3.7e-70	232.8	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2852598777	542	98.32	1	542	4	529	0.0e+00	501.3	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
2852598778	64	3.73	10	57	714	742	5.5e-03	11.7	COG5295	Autotransporter adhesin	715
2852598779	189	91.87	1	188	12	203	9.1e-23	78.5	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852598780	952	99.89	25	951	2	870	0.0e+00	1338.3	COG1048	Aconitase A	861
2852598782	462	89.16	20	459	24	245	1.2e-31	100.1	COG0791	Cell wall-associated hydrolase, NlpC family	197
2852598783	232	70.28	17	230	70	244	2.0e-38	129.4	COG0791	Cell wall-associated hydrolase, NlpC family	197
2852598784	382	97.27	37	357	9	329	6.6e-101	334.1	COG0714	MoxR-like ATPase	329
2852598785	315	66.67	6	307	139	416	6.4e-66	219.6	COG1721	Uncharacterized conserved protein, DUF58 family, contains vWF domain	416
2852598786	335	93.52	5	335	2	376	5.1e-41	137.6	COG2304	Secreted protein containing bacterial Ig-like domain and vWFA domain	399
2852598787	335	93.52	5	334	2	376	1.0e-36	123.2	COG2304	Secreted protein containing bacterial Ig-like domain and vWFA domain	399
2852598788	238	98.13	3	236	5	267	4.4e-71	235.9	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852598789	269	97.3	2	269	2	253	3.5e-88	291.8	COG0623	Enoyl-[acyl-carrier-protein] reductase (NADH)	259
2852598790	340	98.13	1	301	4	318	3.5e-84	279.2	COG0276	Protoheme ferro-lyase (ferrochelatase)	320
2852598792	143	97.87	1	142	4	141	3.2e-37	124.6	COG1585	Membrane protein implicated in regulation of membrane protease activity	140
2852598793	408	32.89	216	316	193	291	8.3e-85	47.8	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
2852598793	408	78.74	3	235	6	242	8.3e-85	247.4	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
2852598794	248	94.2	20	235	12	222	3.7e-54	179.9	COG0398	Uncharacterized membrane protein YdjX, TVP38/TMEM64 family, SNARE-associated domain	223
2852598795	596	91.61	1	530	33	534	3.9e-124	411.7	COG1884	Methylmalonyl-CoA mutase, N-terminal domain/subunit	548
2852598796	741	96.03	588	738	4	148	7.3e-58	190.6	COG2185	Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding)	143
2852598796	741	99.45	27	573	4	548	0.0e+00	819.3	COG1884	Methylmalonyl-CoA mutase, N-terminal domain/subunit	548
2852598797	329	98.45	2	325	4	321	1.1e-127	422.1	COG1703	Putative periplasmic protein kinase ArgK or related GTPase of G3E family	323
2852598798	423	89.6	5	405	33	394	2.4e-59	197.9	COG1680	CubicO group peptidase, beta-lactamase class C family	390
2852598801	214	15.59	62	214	107	207	1.9e-03	11.3	COG1020	Non-ribosomal peptide synthetase component F	642
2852598802	71	98.59	1	71	1	70	1.3e-34	115.2	COG3360	Flavin-binding protein dodecin	71
2852598803	1036	98.31	5	973	17	947	0.0e+00	1037.6	COG0060	Isoleucyl-tRNA synthetase	933
2852598804	68	89.04	1	68	3	67	1.1e-26	89	COG2501	Ribosome-associated protein YbcJ, S4-like RNA binding protein	73
2852598805	156	86.62	1	154	6	128	1.3e-47	157.4	COG4101	Uncharacterized protein, RmlC-like cupin domain	142
2852598806	461	98.66	4	355	1	369	9.1e-94	311.1	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
2852598807	309	90.78	1	309	27	351	2.1e-83	276.7	COG0252	L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D	351
2852598808	187	93.41	18	183	6	161	1.5e-42	141.1	COG0597	Lipoprotein signal peptidase	167
2852598809	304	97.95	1	290	6	291	2.1e-78	260.2	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
2852598810	300	96.95	2	292	7	292	9.1e-93	307.1	COG2962	Uncharacterized membrane protein RarD, contains two EamA domains	293
2852598811	125	93.5	1	120	1	115	4.8e-32	107.2	COG3795	Uncharacterized conserved protein	123
2852598812	406	97.35	5	406	4	407	8.2e-106	350.7	COG4941	Predicted RNA polymerase sigma factor, contains C-terminal TPR domain	415
2852598813	244	79.9	9	239	10	176	3.7e-20	69.3	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852598815	107	83.33	7	107	8	107	1.7e-16	55.9	COG1733	DNA-binding transcriptional regulator, HxlR family	120
2852598816	186	66.13	15	179	63	185	2.4e-07	27.5	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
2852598817	1176	99.14	2	1173	2	1148	0.0e+00	1329	COG0587	DNA polymerase III, alpha subunit	1139
2852598818	277	70.33	1	258	8	218	6.9e-46	153.2	COG3315	O-Methyltransferase involved in polyketide biosynthesis	297
2852598819	248	24.12	174	248	168	222	2.0e-01	9.1	COG4291	Uncharacterized membrane protein	228
2852598819	248	32.46	38	151	27	100	2.0e-01	2.3	COG4291	Uncharacterized membrane protein	228
2852598823	429	98.55	12	356	6	346	7.1e-122	403.2	COG1171	Threonine dehydratase	347
2852598824	580	93.84	1	573	39	632	0.0e+00	542.2	COG0296	1,4-alpha-glucan branching enzyme	628
2852598825	734	16.09	1	147	1	143	0.0e+00	212.7	COG3280	Maltooligosyltrehalose synthase	889
2852598825	734	72.55	151	732	244	888	0.0e+00	625	COG3280	Maltooligosyltrehalose synthase	889
2852598826	715	98.58	1	715	5	698	0.0e+00	912.3	COG1523	Pullulanase/glycogen debranching enzyme	697
2852598827	725	94.34	19	416	8	374	2.8e-89	295.9	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
2852598828	429	97.09	4	429	6	439	0.0e+00	521.2	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
2852598829	381	93.33	8	377	26	389	2.3e-116	385.1	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
2852598830	223	89.24	1	215	4	202	5.7e-50	166.6	COG0132	Dethiobiotin synthetase	223
2852598832	111	87.9	1	110	8	116	5.9e-12	41.8	COG3801	Uncharacterized protein	124
2852598833	878	14.21	679	869	754	880	6.9e-20	41.8	COG2909	ATP-, maltotriose- and DNA-dependent transcriptional regulator MalT	894
2852598833	878	15.88	558	717	537	678	6.9e-20	8.9	COG2909	ATP-, maltotriose- and DNA-dependent transcriptional regulator MalT	894
2852598833	878	51.01	53	611	194	649	6.9e-20	24.5	COG2909	ATP-, maltotriose- and DNA-dependent transcriptional regulator MalT	894
2852598834	192	81.82	3	188	15	185	3.9e-17	57.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852598835	331	95.27	5	330	3	324	2.3e-113	375	COG0502	Biotin synthase or related enzyme	335
2852598837	221	14.48	109	191	225	267	7.3e+00	3	COG2177	Cell division protein FtsX	297
2852598837	221	20.2	24	103	225	284	7.3e+00	4.3	COG2177	Cell division protein FtsX	297
2852598838	445	62.66	143	387	89	281	3.6e-05	17.1	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
2852598839	230	93.15	6	175	9	144	1.5e-31	105.8	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
2852598840	347	94.46	10	342	17	323	3.2e-118	390.9	COG0379	Quinolinate synthase	324
2852598841	515	96.35	10	513	7	507	0.0e+00	598.5	COG0029	Aspartate oxidase	518
2852598842	285	96.79	7	285	6	276	1.7e-96	319	COG0157	Nicotinate-nucleotide pyrophosphorylase	280
2852598845	190	89.95	1	190	12	199	4.2e-21	73.2	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852598846	344	95.75	1	338	3	340	1.4e-47	158.4	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
2852598847	145	86.47	10	141	14	128	5.6e-17	58.4	COG1846	DNA-binding transcriptional regulator, MarR family	126
2852598849	212	98.08	1	207	1	204	4.5e-50	166.2	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2852598851	442	96.5	10	442	13	426	0.0e+00	539.5	COG0141	Histidinol dehydrogenase	425
2852598852	371	96.95	11	371	7	356	2.8e-100	332.1	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
2852598853	204	98.97	2	204	3	195	2.0e-80	265.5	COG0131	Imidazoleglycerol phosphate dehydratase HisB	195
2852598854	206	97.55	2	205	2	200	6.7e-70	231.5	COG0118	Imidazoleglycerol phosphate synthase glutamine amidotransferase subunit HisH	204
2852598855	244	98.34	2	244	3	239	1.0e-80	267	COG0106	Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase	241
2852598856	271	96.14	4	263	10	258	7.2e-61	202.2	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
2852598857	260	98.83	5	260	2	255	6.9e-114	375.9	COG0107	Imidazole glycerol phosphate synthase subunit HisF	256
2852598858	115	91.96	2	110	8	110	1.9e-41	137	COG0139	Phosphoribosyl-AMP cyclohydrolase	111
2852598860	261	98.88	2	255	3	267	2.2e-69	230.5	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852598861	265	87.94	1	228	30	255	4.0e-69	229.2	COG1119	ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA	257
2852598862	382	66.85	70	378	99	344	8.8e-39	129.9	COG2208	Serine phosphatase RsbU, regulator of sigma subunit	367
2852598863	266	94.58	4	266	15	293	6.7e-38	127.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852598864	156	97.45	1	155	3	155	2.7e-51	170	COG1225	Peroxiredoxin	157
2852598866	508	99.36	27	507	2	465	0.0e+00	529.7	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
2852598868	272	99.61	7	260	1	253	2.2e-92	305.3	COG0134	Indole-3-glycerol phosphate synthase	254
2852598869	419	97.98	22	416	3	390	0.0e+00	647.4	COG0133	Tryptophan synthase beta chain	396
2852598870	262	99.62	1	258	1	264	1.1e-84	280	COG0159	Tryptophan synthase alpha chain	265
2852598871	646	28.32	428	476	66	97	1.3e+00	3	COG2151	Metal-sulfur cluster biosynthetic enzyme	111
2852598871	646	35.4	474	527	66	105	1.3e+00	3.3	COG2151	Metal-sulfur cluster biosynthetic enzyme	111
2852598871	646	36.28	382	433	66	106	1.3e+00	4.3	COG2151	Metal-sulfur cluster biosynthetic enzyme	111
2852598871	646	96.53	2	303	5	282	5.2e-73	241.8	COG0682	Prolipoprotein diacylglyceryltransferase	287
2852598873	147	89.69	55	147	8	94	1.3e-09	34.7	COG2314	Uncharacterized membrane protein YozV, TM2 domain	95
2852598875	1485	10.02	611	667	358	406	0.0e+00	2.6	COG0069	Glutamate synthase domain 2	485
2852598875	1485	96.24	1	367	15	372	3.2e-121	401	COG0067	Glutamate synthase domain 1	371
2852598875	1485	96.71	1180	1479	6	299	1.4e-99	329.7	COG0070	Glutamate synthase domain 3	301
2852598875	1485	98.98	685	1174	4	487	0.0e+00	680.6	COG0069	Glutamate synthase domain 2	485
2852598876	502	98.91	22	488	4	456	0.0e+00	483.8	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
2852598877	472	99.37	1	467	4	478	0.0e+00	582.7	COG0469	Pyruvate kinase	477
2852598878	289	97.59	2	288	5	287	2.0e-92	305.9	COG1946	Acyl-CoA thioesterase	289
2852598879	465	77.45	18	460	106	524	5.6e-92	305.3	COG2898	Lysylphosphatidylglycerol synthetase, C-terminal domain, DUF2156 family	538
2852598881	491	30.37	318	483	360	533	1.0e-77	113.7	COG4987	ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components	573
2852598881	491	53.58	2	321	17	323	1.0e-77	144.8	COG4987	ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components	573
2852598882	492	33.81	308	492	339	527	0.0e+00	149.2	COG4988	ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components	559
2852598882	492	54.74	4	317	2	307	0.0e+00	294.1	COG4988	ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components	559
2852598883	346	97.39	1	338	7	342	2.2e-101	336.2	COG1294	Cytochrome bd-type quinol oxidase, subunit 2	346
2852598884	488	97.59	1	479	2	446	0.0e+00	539.1	COG1271	Cytochrome bd-type quinol oxidase, subunit 1	457
2852598885	201	91.94	1	182	13	183	1.2e-39	132.1	COG3247	Uncharacterized membrane protein HdeD, DUF308 family	185
2852598887	305	97.53	10	301	2	277	7.1e-45	150	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2852598888	309	91.23	25	286	19	226	3.6e-63	209.5	COG0765	ABC-type amino acid transport system, permease component	222
2852598889	254	99.17	4	254	2	241	1.9e-110	364.2	COG1126	ABC-type polar amino acid transport system, ATPase component	240
2852598890	373	78.67	10	372	80	374	7.2e-21	67.3	COG4585	Signal transduction histidine kinase	365
2852598891	220	98.1	7	218	3	209	2.5e-56	187.1	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2852598893	163	91.72	5	161	12	155	6.1e-32	107.3	COG0783	DNA-binding ferritin-like protein (oxidative damage protectant)	156
2852598894	199	82.3	15	197	22	193	1.5e-13	48.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852598895	271	93.9	2	264	18	294	2.4e-46	155	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852598896	437	93.03	185	425	11	237	4.9e-48	159.8	COG2114	Adenylate cyclase, class 3	227
2852598897	651	64.63	376	459	11	63	2.2e-01	9.6	COG4423	Uncharacterized protein	81
2852598899	314	99.03	16	314	2	307	2.9e-89	295.8	COG0010	Arginase family enzyme	305
2852598900	525	95.68	4	525	2	532	0.0e+00	468.2	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
2852598901	482	94.8	1	477	5	478	2.4e-78	260.4	COG0591	Na+/proline symporter	493
2852598902	136	27.44	10	134	363	508	2.6e-04	16.5	COG5651	PPE-repeat protein	490
2852598904	203	97.94	7	200	4	193	4.9e-74	244.6	COG3707	Two-component response regulator, AmiR/NasT family, consists of REC and RNA-binding antiterminator (ANTAR) domains	194
2852598905	385	90.98	15	385	9	341	7.6e-45	150	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2852598906	348	97.01	28	345	5	296	5.7e-71	235.7	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2852598907	390	95.98	24	371	11	320	5.5e-85	281.8	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2852598908	275	98.82	17	269	3	253	3.1e-104	344.2	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2852598909	246	99.16	8	245	3	237	7.0e-95	313.2	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2852598910	76	71.57	1	76	14	86	5.1e-22	74.3	COG1872	Uncharacterized conserved protein YggU, UPF0235/DUF167 family	102
2852598912	208	74.58	5	208	50	225	5.6e-40	133.8	COG5522	Uncharacterized membrane protein YwaF	236
2852598913	399	99.49	3	399	2	393	9.3e-74	245.1	COG0183	Acetyl-CoA acetyltransferase	392
2852598914	145	87.94	3	144	17	140	4.6e-26	87.6	COG1545	Uncharacterized OB-fold protein, contains Zn-ribbon domain	140
2852598917	221	52.2	2	221	32	185	1.2e-13	44.9	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852598918	378	91.86	1	372	2	362	1.9e-58	195.1	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2852598919	304	98.67	1	295	1	297	3.5e-65	217.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2852598920	853	60.6	319	670	119	341	5.4e-04	12.6	COG0457	Tetratricopeptide (TPR) repeat	291
2852598920	853	62.5	792	851	11	60	7.0e-13	42.9	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2852598922	908	95.14	325	907	29	596	0.0e+00	676.1	COG0749	DNA polymerase I - 3'-5' exonuclease and polymerase domains	593
2852598923	168	94.85	10	155	6	134	1.3e-14	51	COG3631	Ketosteroid isomerase-related protein	133
2852598924	282	98.55	3	271	2	273	2.6e-31	105.5	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
2852598925	192	90.91	1	192	8	197	7.3e-18	62.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852598926	387	84.7	17	290	25	262	7.6e-26	87.1	COG2339	Membrane proteinase PrsW, cleaves anti-sigma factor RsiW, M82 family	274
2852598927	481	84.91	14	480	4	470	0.0e+00	555.7	COG0539	Ribosomal protein S1	541
2852598928	386	95.52	1	198	2	193	2.4e-58	193.4	COG0237	Dephospho-CoA kinase	201
2852598931	256	100	1	255	1	274	5.5e-52	168.9	COG0266	Formamidopyrimidine-DNA glycosylase	273
2852598932	298	98.34	1	297	4	300	7.2e-93	307.5	COG3285	Eukaryotic-type DNA primase	299
2852598933	314	65.45	1	314	154	475	5.5e-85	282.6	COG1793	ATP-dependent DNA ligase	444
2852598934	146	84.7	1	146	22	176	1.6e-44	148.3	COG2306	Predicted RNA-binding protein, associated with RNAse of E/G family	183
2852598935	184	87.56	1	182	19	201	5.2e-15	53.2	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852598936	259	98.49	1	256	5	265	1.8e-67	224	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2852598937	716	99.1	24	711	4	660	0.0e+00	1078.9	COG0556	Excinuclease UvrABC helicase subunit UvrB	663
2852598939	480	37.34	304	473	52	194	2.5e-26	9.5	COG0477	MFS family permease	338
2852598939	480	87.47	12	330	7	341	2.5e-26	82.6	COG0477	MFS family permease	338
2852598940	238	97.89	1	238	4	235	8.3e-62	205.1	COG0775	Nucleoside phosphorylase	234
2852598941	242	74.34	16	235	10	177	5.1e-48	160.2	COG1285	Uncharacterized membrane protein YhiD, involved in acid resistance	221
2852598942	252	90	3	245	11	226	3.1e-68	226.3	COG4312	Predicted dithiol-disulfide oxidoreductase, DUF899 family	247
2852598944	346	51.25	87	344	42	184	5.9e-08	29.7	COG0500	SAM-dependent methyltransferase	257
2852598945	143	71.34	2	131	9	120	3.4e-05	20.2	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
2852598946	265	96.4	1	265	2	269	2.2e-57	190.8	COG0388	Predicted amidohydrolase	274
2852598947	286	95.59	8	286	8	289	1.2e-24	84.1	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852598948	215	94.06	7	212	7	196	2.6e-41	137.4	COG1573	Uracil-DNA glycosylase	202
2852598949	512	89.33	26	512	59	552	3.9e-78	260	COG5305	Uncharacterized membrane protein	552
2852598951	148	96.23	1	148	5	157	7.7e-29	98.1	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2852598952	294	96.39	1	294	5	324	1.8e-90	299.5	COG3588	Fructose-bisphosphate aldolase class 1	332
2852598953	435	96.2	21	433	16	420	1.6e-101	336.6	COG2124	Cytochrome P450	411
2852598954	226	92.31	2	226	18	257	5.0e-38	127.7	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2852598955	969	99.47	1	951	4	939	0.0e+00	1466.3	COG0178	Excinuclease UvrABC ATPase subunit	935
2852598963	86	26.55	9	84	163	222	1.3e-10	37.9	COG1842	Phage shock protein A	225
2852598964	472	51.54	282	442	157	323	2.0e-45	88.7	COG0627	S-formylglutathione hydrolase FrmB	316
2852598964	472	59.88	50	297	8	201	2.0e-45	69.5	COG0627	S-formylglutathione hydrolase FrmB	316
2852598965	1098	97.05	603	1098	14	507	0.0e+00	579.8	COG1190	Lysyl-tRNA synthetase (class II)	502
2852598965	1098	99.82	32	568	2	541	0.0e+00	434.8	COG2898	Lysylphosphatidylglycerol synthetase, C-terminal domain, DUF2156 family	538
2852598967	180	80.11	1	143	34	174	6.0e-62	204.8	COG0290	Translation initiation factor IF-3	176
2852598968	64	96.92	1	64	1	63	1.2e-27	92.7	COG0291	Ribosomal protein L35	65
2852598969	129	99.15	1	118	1	117	1.4e-50	166.9	COG0292	Ribosomal protein L20	118
2852598970	247	93.92	1	247	15	261	1.4e-58	194.8	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
2852598972	412	97.99	1	412	3	393	4.2e-97	322.3	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852598973	340	91	1	287	28	300	4.6e-114	376.5	COG3662	Uncharacterized conserved protein, DUF2236 family	300
2852598974	290	84.43	47	282	26	231	1.0e-33	113	COG2114	Adenylate cyclase, class 3	227
2852598976	347	98.22	9	342	5	335	6.1e-112	370.8	COG0016	Phenylalanyl-tRNA synthetase alpha subunit	335
2852598977	832	99.69	150	831	2	651	0.0e+00	620.8	COG0072	Phenylalanyl-tRNA synthetase beta subunit	650
2852598978	400	90.74	4	399	28	409	3.9e-76	252.9	COG2124	Cytochrome P450	411
2852598979	344	99.71	1	344	2	349	1.4e-110	366.2	COG0002	N-acetyl-gamma-glutamylphosphate reductase	349
2852598980	404	99.01	5	404	5	405	0.0e+00	466.9	COG1364	N-acetylglutamate synthase (N-acetylornithine aminotransferase)	404
2852598981	290	99.62	23	289	1	264	5.4e-99	327.1	COG0548	Acetylglutamate kinase	265
2852598982	390	96.54	1	390	10	400	0.0e+00	488	COG4992	Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase	404
2852598983	307	98.07	1	305	6	310	1.1e-120	399.1	COG0078	Ornithine carbamoyltransferase	310
2852598984	162	97.33	3	158	3	148	3.4e-47	156.7	COG1438	Arginine repressor	150
2852598985	403	98.26	3	403	4	399	0.0e+00	558.3	COG0137	Argininosuccinate synthase	403
2852598986	470	98.69	4	463	3	455	0.0e+00	590.8	COG0165	Argininosuccinate lyase	459
2852598987	583	99.07	2	498	2	531	0.0e+00	462	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
2852598988	989	92.48	2	413	33	450	2.2e-104	345.9	COG3243	Poly(3-hydroxyalkanoate) synthetase	445
2852598988	989	97.18	438	964	6	557	9.9e-42	139	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2852598990	71	98.48	2	60	1	65	5.1e-21	70.7	COG2835	Uncharacterized conserved protein YbaR, Trm112 family	60
2852598991	204	36.84	6	198	3	79	3.7e-18	63	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852598992	272	66.89	17	271	94	289	4.0e-25	83.9	COG0842	ABC-type multidrug transport system, permease component	286
2852598993	254	73.86	14	250	4	229	3.4e-71	236.7	COG1131	ABC-type multidrug transport system, ATPase component	293
2852598994	203	96	1	196	8	199	3.3e-66	218.9	COG2094	3-methyladenine DNA glycosylase Mpg	200
2852598996	424	98.51	1	423	5	402	0.0e+00	455.9	COG0162	Tyrosyl-tRNA synthetase	401
2852598998	144	64.97	2	111	10	111	8.1e-04	13.9	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
2852598999	164	97.02	3	157	5	167	1.2e-54	181.8	COG0350	O6-methylguanine-DNA--protein-cysteine methyltransferase	168
2852599000	491	95.77	1	190	4	184	3.4e-62	205.8	COG2169	Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), contains Zn-binding and two AraC-type DNA-binding domains	187
2852599000	491	99.31	207	491	2	288	2.6e-68	226.7	COG0122	3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase	285
2852599001	44	9.83	3	42	265	293	3.2e-03	14.1	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852599003	260	97	4	255	8	266	7.9e-36	120	COG0725	ABC-type molybdate transport system, periplasmic component	258
2852599005	529	91.39	270	529	6	228	2.8e-55	182.4	COG2114	Adenylate cyclase, class 3	227
2852599006	223	88.54	1	223	29	252	7.1e-80	264.2	COG1637	Endonuclease NucS, RecB family	253
2852599008	156	98.63	18	151	3	146	1.2e-16	58.8	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2852599009	376	94.67	1	376	20	392	9.0e-117	387	COG0183	Acetyl-CoA acetyltransferase	392
2852599011	296	98.36	15	296	6	305	4.1e-73	243.1	COG3118	Negative regulator of GroEL, contains thioredoxin-like and TPR-like domains	304
2852599012	735	99.68	109	734	2	632	0.0e+00	827.1	COG0296	1,4-alpha-glucan branching enzyme	628
2852599013	695	95.55	212	651	7	500	4.7e-39	122	COG0366	Glycosidase	505
2852599014	870	98.8	11	811	6	748	0.0e+00	743.3	COG0058	Glucan phosphorylase	750
2852599015	283	13.03	162	215	182	227	4.9e-36	17.7	COG4257	Streptogramin lyase	353
2852599015	283	19.55	210	283	62	130	4.9e-36	28.1	COG4257	Streptogramin lyase	353
2852599015	283	24.65	2	99	61	147	4.9e-36	50.3	COG4257	Streptogramin lyase	353
2852599015	283	24.65	79	173	51	137	4.9e-36	39.3	COG4257	Streptogramin lyase	353
2852599017	482	85.47	2	273	41	293	3.9e-27	89	COG2321	Predicted metalloprotease	295
2852599018	630	95.87	1	629	23	672	0.0e+00	452.1	COG1199	Rad3-related DNA helicase	654
2852599019	431	97.07	4	401	13	410	3.7e-102	338.4	COG1488	Nicotinic acid phosphoribosyltransferase	405
2852599020	100	85.98	1	100	11	102	1.8e-31	104.8	COG2127	ATP-dependent Clp protease adapter protein ClpS	107
2852599022	339	93.97	1	339	15	341	8.6e-108	357	COG3191	L-aminopeptidase/D-esterase	348
2852599023	137	88.89	1	136	2	121	3.3e-28	95	COG1310	Proteasome lid subunit RPN8/RPN11, contains Jab1/MPN domain metalloenzyme (JAMM) motif	134
2852599024	90	98.81	2	90	2	84	9.2e-21	71	COG1977	Molybdopterin converting factor, small subunit	84
2852599025	320	99.34	3	301	2	301	4.4e-97	321.2	COG0031	Cysteine synthase	300
2852599026	227	87.72	9	221	22	221	1.0e-28	97.1	COG0705	Membrane associated serine protease, rhomboid family	228
2852599027	274	96.64	2	270	5	263	1.3e-89	296.4	COG0796	Glutamate racemase	269
2852599028	224	88.45	1	222	34	301	6.9e-45	148.2	COG1234	Ribonuclease BN, tRNA processing enzyme	292
2852599029	260	96.54	1	240	8	230	4.8e-91	300.7	COG0689	Ribonuclease PH	230
2852599030	181	83.59	1	179	31	193	3.3e-60	199.6	COG0127	Inosine/xanthosine triphosphate pyrophosphatase, all-alpha NTP-PPase family	194
2852599031	394	89.46	13	369	8	355	8.7e-67	222	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
2852599033	124	93.75	1	123	1	120	4.4e-36	120.5	COG4578	DNA-binding transcriptional regulator of glucitol operon	128
2852599036	209	83.25	12	204	16	189	3.3e-15	53.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852599038	287	77.27	148	286	24	125	8.7e-22	73.5	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2852599039	420	70.39	67	377	89	302	3.9e-11	38.3	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
2852599040	135	92.75	64	131	4	67	1.1e-13	47.5	COG3585	Molybdopterin-binding protein	69
2852599041	250	97.75	1	250	6	266	1.2e-60	201.5	COG0725	ABC-type molybdate transport system, periplasmic component	258
2852599042	792	26.54	693	787	225	310	2.6e-23	48.2	COG0392	Uncharacterized membrane protein YbhN, UPF0104 family	322
2852599042	792	75.93	387	697	47	292	2.6e-23	46.2	COG0392	Uncharacterized membrane protein YbhN, UPF0104 family	322
2852599043	445	47.26	242	442	10	190	7.4e-39	30.6	COG0477	MFS family permease	338
2852599043	445	75.72	20	283	4	293	7.4e-39	105.9	COG0477	MFS family permease	338
2852599044	482	91.39	249	482	5	227	1.9e-45	151	COG2114	Adenylate cyclase, class 3	227
2852599046	497	96.65	1	497	12	560	3.9e-83	276.2	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2852599047	273	79.1	2	257	3	214	7.4e-45	150.1	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852599048	525	95.8	3	523	24	548	0.0e+00	629.1	COG1884	Methylmalonyl-CoA mutase, N-terminal domain/subunit	548
2852599049	132	84.77	1	132	21	148	1.9e-43	144.3	COG2185	Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding)	143
2852599050	318	86.88	4	307	19	316	8.5e-44	146.4	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852599051	348	93.02	1	347	7	379	8.5e-91	301.3	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2852599052	342	98.51	11	279	5	268	2.0e-57	190.9	COG1018	Ferredoxin-NADP reductase	266
2852599053	465	93.84	2	464	26	558	1.3e-95	314.2	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2852599055	362	97.49	1	361	7	395	5.9e-70	231.3	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852599056	252	95.85	1	252	6	259	4.4e-62	206.4	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2852599057	152	45.05	3	146	10	132	1.3e-13	43.4	COG2514	Catechol-2,3-dioxygenase	265
2852599058	279	98.13	1	267	5	267	1.7e-37	125.8	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852599059	246	97.01	1	241	1	260	6.7e-51	169.9	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852599060	254	99.25	1	250	1	266	1.9e-43	145.5	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852599061	379	99.49	1	377	2	393	8.1e-107	354.2	COG0183	Acetyl-CoA acetyltransferase	392
2852599062	291	98.14	1	290	2	318	4.9e-85	280.5	COG1703	Putative periplasmic protein kinase ArgK or related GTPase of G3E family	323
2852599063	199	88.52	8	198	14	198	1.3e-22	77.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852599066	198	84.04	2	198	32	210	3.0e-41	137.6	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
2852599068	533	11.84	396	533	346	412	1.2e-33	16.5	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
2852599068	533	18.73	1	146	4	109	1.2e-33	64.8	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
2852599068	533	20.85	185	364	158	275	1.2e-33	34.4	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
2852599069	238	86.99	22	237	1	214	6.4e-34	107	COG1414	DNA-binding transcriptional regulator, IclR family	246
2852599070	287	98.31	17	287	4	293	1.4e-42	142.8	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852599071	556	97.96	3	381	3	387	7.8e-73	242.4	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2852599073	581	10.6	501	577	356	415	3.8e-38	17.3	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
2852599073	581	12.54	409	502	400	470	3.8e-38	8.4	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
2852599073	581	17.84	4	128	6	106	3.8e-38	71.9	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
2852599073	581	26.68	204	375	138	288	3.8e-38	24.5	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
2852599074	442	95.34	14	354	15	341	1.5e-46	155	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852599075	270	98.13	8	262	4	266	4.2e-35	117.8	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852599076	329	80.82	88	329	40	216	4.7e-12	40.8	COG1878	Kynurenine formamidase	218
2852599077	196	94.02	11	195	3	175	5.6e-23	78.1	COG0431	NAD(P)H-dependent FMN reductase	184
2852599078	285	98.31	5	274	4	293	3.0e-29	98.9	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852599079	266	98.51	3	259	3	266	1.4e-67	224.6	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852599080	217	93.3	2	217	8	202	2.3e-10	38	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852599081	64	98.53	1	64	2	68	1.4e-14	50.7	COG1141	Ferredoxin	68
2852599082	407	88.36	3	407	48	419	3.0e-82	273.2	COG2124	Cytochrome P450	411
2852599083	392	69.41	88	392	92	302	1.4e-12	43.7	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
2852599084	411	96.41	16	410	8	383	6.7e-47	155.6	COG0006	Xaa-Pro aminopeptidase	384
2852599085	376	95.38	7	371	11	382	1.3e-30	102.7	COG0006	Xaa-Pro aminopeptidase	384
2852599086	319	79.62	6	295	7	217	9.8e-34	112.1	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2852599087	789	93.52	1	364	7	381	0.0e+00	151.1	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2852599087	789	98	364	778	9	401	0.0e+00	325.3	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2852599088	268	98.51	8	251	3	266	2.7e-60	200.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852599089	279	90.3	2	269	3	244	3.7e-49	164.2	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852599090	358	95.02	1	309	3	307	5.1e-36	121.2	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2852599091	268	76.25	5	260	46	244	1.4e-27	93	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
2852599093	279	98.13	3	277	4	266	3.2e-64	213.6	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852599094	403	93.59	5	403	23	416	2.1e-81	270.1	COG2124	Cytochrome P450	411
2852599095	273	38.28	24	146	21	131	9.4e-39	60.4	COG1946	Acyl-CoA thioesterase	289
2852599095	273	42.07	139	273	164	285	9.4e-39	67.9	COG1946	Acyl-CoA thioesterase	289
2852599096	217	75.12	14	208	11	167	1.9e-16	57.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852599097	391	26.32	273	391	293	397	3.4e-73	40.7	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852599097	391	61.65	2	257	7	252	3.4e-73	203.6	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852599098	260	87.55	2	241	8	239	7.8e-58	192.2	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2852599099	264	34.34	41	256	248	384	1.4e-24	83.3	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852599100	374	97.24	1	374	8	395	2.5e-71	237.3	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852599102	405	95.58	3	405	15	403	1.5e-80	267.5	COG1228	Imidazolonepropionase or related amidohydrolase	406
2852599104	427	52.13	21	388	9	204	2.0e-46	155.3	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
2852599105	179	80.65	5	173	33	182	1.2e-15	54.5	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
2852599106	430	81.91	52	377	54	302	1.3e-12	43.4	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
2852599107	392	99.75	5	392	1	398	4.4e-107	355.2	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852599108	252	99.25	5	251	2	267	2.2e-68	227.2	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852599109	399	98.25	1	398	8	401	1.4e-112	373.1	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2852599110	263	98.11	1	253	6	265	2.4e-70	233.5	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2852599111	381	99.49	1	380	1	392	6.3e-123	407.2	COG0183	Acetyl-CoA acetyltransferase	392
2852599112	382	96.99	3	382	7	393	3.6e-114	378.4	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852599113	305	96.01	7	304	2	290	4.1e-53	177.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2852599114	423	64.36	25	420	10	251	7.5e-44	146.7	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
2852599116	276	97.56	4	276	4	283	7.4e-48	159.9	COG2175	Taurine dioxygenase, alpha-ketoglutarate-dependent	286
2852599117	107	21.57	6	104	18	91	2.0e-15	53.3	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852599119	195	74.19	18	186	39	176	2.6e-11	40.5	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
2852599120	200	77.99	3	196	12	174	4.2e-21	73	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852599122	321	100	1	320	1	331	9.1e-81	268.3	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2852599123	339	90.83	2	316	7	303	2.1e-57	191	COG3173	Predicted  kinase, aminoglycoside phosphotransferase (APT) family	321
2852599124	433	99	3	402	2	396	5.0e-87	289	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852599125	218	78.47	10	213	11	174	6.3e-20	69.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852599126	189	56.94	1	185	15	133	7.8e-16	56	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852599127	276	99.25	2	273	2	267	5.8e-57	189.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852599128	267	98.13	3	265	4	266	5.3e-58	193.2	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852599129	294	62.9	158	259	38	115	7.6e-30	44.7	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
2852599129	294	66.13	7	123	37	118	7.6e-30	53.7	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
2852599130	278	98.13	3	276	4	266	9.4e-62	205.5	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852599131	398	92.16	2	398	31	418	2.3e-88	293.3	COG2124	Cytochrome P450	411
2852599132	387	100	1	386	1	366	3.8e-110	361.3	COG1062	Zn-dependent alcohol dehydrogenase	366
2852599133	489	98.33	5	486	2	472	0.0e+00	479.3	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2852599134	262	75.37	7	235	8	209	8.9e-36	120.3	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852599135	210	92.34	6	205	9	201	9.5e-23	78.3	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852599136	380	82.24	10	337	30	330	1.5e-09	33.4	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2852599137	367	95.71	1	359	2	336	3.9e-52	173.7	COG3804	Uncharacterized protein	350
2852599138	412	92.4	4	412	31	419	8.7e-86	284.9	COG2124	Cytochrome P450	411
2852599139	349	96.86	1	348	3	341	7.7e-60	199.2	COG3804	Uncharacterized protein	350
2852599140	308	92.54	6	272	3	250	9.1e-45	149.8	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852599141	364	97.43	6	358	3	343	1.4e-59	198.1	COG3804	Uncharacterized protein	350
2852599142	280	98.51	6	261	4	267	3.9e-34	114.5	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852599143	287	91.42	3	271	3	247	2.6e-45	151.6	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852599144	252	90.3	6	245	7	248	2.5e-32	109.1	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852599146	398	93.82	1	398	24	418	4.4e-85	282.6	COG2124	Cytochrome P450	411
2852599148	368	94	8	354	4	332	5.6e-65	215.9	COG3804	Uncharacterized protein	350
2852599149	273	98.88	2	271	2	266	1.1e-58	195.4	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852599150	59	19.92	1	57	3	51	2.1e-11	40.6	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
2852599151	189	71.64	1	179	76	267	2.4e-32	109	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852599152	359	98	4	357	3	345	3.4e-80	266	COG3804	Uncharacterized protein	350
2852599153	545	96.3	5	540	12	558	1.6e-87	290.3	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2852599154	187	83.94	13	139	11	125	6.2e-03	12.6	COG4319	Ketosteroid isomerase homolog	137
2852599155	395	96.51	1	394	15	401	3.9e-87	289.3	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2852599156	409	95.49	2	409	19	420	1.7e-89	297.1	COG2124	Cytochrome P450	411
2852599158	204	93.3	2	202	5	199	7.9e-23	78.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852599159	389	96.45	6	386	3	382	3.6e-44	147.9	COG0183	Acetyl-CoA acetyltransferase	392
2852599160	150	85.53	2	145	11	146	3.6e-06	22.5	COG2030	Acyl dehydratase	159
2852599161	369	97.49	1	364	1	389	3.4e-70	233.6	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852599162	137	79.43	3	134	14	125	1.3e-25	86	COG1545	Uncharacterized OB-fold protein, contains Zn-ribbon domain	140
2852599163	192	22.01	115	179	108	142	4.3e-04	4.5	COG2030	Acyl dehydratase	159
2852599163	192	23.9	14	74	29	66	4.3e-04	9.9	COG2030	Acyl dehydratase	159
2852599164	393	99.5	1	387	1	397	8.8e-90	298.2	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852599165	400	92.87	2	398	29	419	1.5e-110	366.5	COG2124	Cytochrome P450	411
2852599166	486	97.91	11	485	4	472	0.0e+00	494.3	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2852599167	789	92.27	1	366	8	377	0.0e+00	230.3	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2852599167	789	98.5	378	782	7	401	0.0e+00	327.9	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2852599168	1177	96.41	45	639	8	598	2.5e-100	327.5	COG1022	Long-chain acyl-CoA synthetase (AMP-forming)	613
2852599168	1177	99.48	768	1164	2	382	4.4e-120	397.8	COG3320	Thioester reductase domain of alpha aminoadipate reductase Lys2 and NRPSs	382
2852599171	89	34.7	1	89	140	215	6.7e-04	15.4	COG1878	Kynurenine formamidase	218
2852599172	465	66.36	36	278	67	283	3.2e-18	61.8	COG3173	Predicted  kinase, aminoglycoside phosphotransferase (APT) family	321
2852599173	419	90.26	14	413	41	420	4.1e-93	308.9	COG2124	Cytochrome P450	411
2852599175	261	93.1	42	261	10	225	1.0e-33	113.1	COG1802	DNA-binding transcriptional regulator, GntR family	230
2852599176	410	85.18	1	409	66	473	0.0e+00	481.2	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2852599177	374	96.86	1	359	2	340	8.2e-62	205.6	COG3804	Uncharacterized protein	350
2852599178	385	95.14	1	327	16	367	3.0e-60	200.6	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852599179	342	88.38	2	342	9	335	1.9e-63	211.3	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852599180	364	91.35	2	357	13	350	1.0e-59	198.9	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852599181	466	97.03	1	364	4	362	2.8e-74	246.8	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852599182	348	77.57	1	328	48	334	1.2e-52	175.7	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852599183	520	98.11	1	364	1	363	4.4e-68	226.4	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852599185	157	85.53	6	156	19	154	1.1e-35	118.6	COG2030	Acyl dehydratase	159
2852599186	397	82.57	57	395	51	301	2.2e-20	69.6	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
2852599187	210	99.03	10	207	1	204	2.5e-29	99	COG1335	Nicotinamidase-related amidase	205
2852599189	300	76.38	6	298	18	279	9.8e-43	142.8	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852599190	368	96.24	1	367	8	391	3.1e-63	210.7	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852599191	399	80.92	67	399	56	301	5.4e-20	68.2	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
2852599192	322	30.58	4	115	11	132	2.0e-37	38.3	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852599192	322	37.84	162	322	242	392	2.0e-37	93.2	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852599193	399	96.99	7	399	10	396	1.9e-71	237.6	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852599194	512	95.95	1	511	13	557	4.4e-78	259.5	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2852599195	293	98.88	3	284	2	266	1.4e-44	149.1	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852599196	287	18.29	231	287	194	238	3.1e-24	11.9	COG1414	DNA-binding transcriptional regulator, IclR family	246
2852599196	287	74.8	7	204	3	186	3.1e-24	70.8	COG1414	DNA-binding transcriptional regulator, IclR family	246
2852599197	346	93.2	1	340	13	341	7.4e-54	178.2	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
2852599199	277	84.53	4	268	4	227	1.7e-50	168.1	COG0300	Short-chain dehydrogenase	265
2852599200	318	65.6	6	296	22	246	4.8e-32	107.3	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852599202	113	6.29	76	111	117	138	6.3e-17	4.7	COG3804	Uncharacterized protein	350
2852599202	113	18.29	3	82	13	76	6.3e-17	52.6	COG3804	Uncharacterized protein	350
2852599204	392	90.13	38	392	28	301	3.2e-18	62.5	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
2852599205	483	89.67	12	480	43	537	4.4e-68	223.5	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2852599206	266	98.87	1	259	4	265	7.7e-53	176	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2852599207	270	98.87	1	261	4	265	1.0e-60	201.9	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2852599208	415	96.99	6	401	11	397	6.7e-63	209.5	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852599209	268	96.98	5	265	9	265	5.0e-58	193	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2852599210	416	25.16	16	160	38	77	2.4e-05	17.4	COG2030	Acyl dehydratase	159
2852599211	271	96.98	3	268	9	265	1.1e-59	198.4	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2852599212	298	79.48	14	278	1	213	6.0e-50	166.9	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852599213	520	96.13	29	517	15	560	5.4e-60	198.9	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2852599214	431	93.42	52	377	19	302	1.0e-11	40.5	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
2852599215	142	75.89	5	135	16	122	7.1e-22	73.9	COG1545	Uncharacterized OB-fold protein, contains Zn-ribbon domain	140
2852599216	381	99.49	3	381	2	393	1.6e-52	175.4	COG0183	Acetyl-CoA acetyltransferase	392
2852599217	235	87.06	2	228	33	254	5.7e-56	186	COG3836	2-keto-3-deoxy-L-rhamnonate aldolase RhmA	255
2852599219	363	83.13	34	337	45	315	3.1e-85	282.2	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
2852599220	274	99.62	1	271	2	265	3.5e-60	200.1	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2852599221	395	71.38	46	395	84	300	3.2e-17	59.3	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
2852599222	262	50.72	35	232	15	120	9.5e-14	48.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852599223	386	98.5	1	386	4	396	1.8e-65	217.8	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852599224	339	29.57	2	138	14	131	2.2e-29	22.9	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852599224	339	31.33	174	336	248	372	2.2e-29	81.9	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852599225	145	78.72	4	137	30	140	1.8e-23	79.3	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
2852599226	302	81.89	1	268	11	227	2.8e-51	170.8	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2852599227	370	98	8	359	4	346	1.4e-77	257.3	COG3804	Uncharacterized protein	350
2852599228	219	94.44	11	210	7	210	2.6e-25	85.5	COG0778	Nitroreductase	207
2852599229	312	62.1	7	311	12	224	5.8e-49	163.3	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852599230	184	81.82	1	182	5	175	6.5e-16	56.2	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852599231	143	43.8	4	105	7	66	3.0e-07	26.8	COG4319	Ketosteroid isomerase homolog	137
2852599232	288	25.2	201	288	181	242	7.3e-30	17	COG1414	DNA-binding transcriptional regulator, IclR family	246
2852599232	288	74.8	6	209	4	187	7.3e-30	82.4	COG1414	DNA-binding transcriptional regulator, IclR family	246
2852599234	344	97.82	8	335	5	318	1.0e-53	179.3	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2852599235	126	85	5	125	9	110	1.7e-35	117.7	COG1733	DNA-binding transcriptional regulator, HxlR family	120
2852599236	192	76.56	1	191	5	164	2.7e-23	80.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852599237	218	23.17	156	215	185	241	4.8e-27	10.4	COG1414	DNA-binding transcriptional regulator, IclR family	246
2852599237	218	55.28	17	151	2	137	4.8e-27	84.1	COG1414	DNA-binding transcriptional regulator, IclR family	246
2852599238	112	45.54	16	95	29	79	1.0e-03	15.5	COG4538	Uncharacterized protein	112
2852599239	366	97.86	6	366	5	369	2.7e-69	230.1	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
2852599240	531	97.66	1	531	1	542	7.5e-104	344.7	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
2852599241	343	100	5	330	1	331	8.2e-82	271.7	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2852599242	356	92.23	15	353	13	297	1.5e-25	86.1	COG3386	Sugar lactone lactonase YvrE	307
2852599243	413	97.3	4	410	11	370	2.6e-93	309.4	COG5276	Uncharacterized conserved protein	370
2852599244	343	100	1	337	1	331	3.3e-68	227	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2852599245	240	68.85	2	231	33	242	2.5e-24	82.3	COG2113	ABC-type proline/glycine betaine transport system, periplasmic component	302
2852599246	424	93.82	1	422	24	418	5.3e-81	269.2	COG2124	Cytochrome P450	411
2852599247	279	98.13	3	277	4	266	2.9e-61	203.9	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852599248	317	90.67	3	310	21	331	2.0e-37	125.5	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852599250	306	97.2	4	300	3	314	4.7e-41	137.7	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2852599251	391	97.99	2	391	7	397	9.6e-71	232.3	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852599253	200	80.86	2	198	11	179	4.2e-24	82.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852599254	307	93	9	306	18	336	2.5e-59	191.4	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852599255	481	98.54	4	481	3	474	0.0e+00	522.2	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2852599256	421	96.28	22	420	10	371	6.1e-47	156.9	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
2852599258	416	97.05	1	416	8	402	1.3e-74	248.1	COG1228	Imidazolonepropionase or related amidohydrolase	406
2852599259	146	85.71	2	130	15	128	5.5e-22	74.6	COG1846	DNA-binding transcriptional regulator, MarR family	126
2852599260	99	79.61	5	99	12	93	4.6e-16	55	COG0633	Ferredoxin	102
2852599261	246	97.76	1	245	5	266	1.7e-68	227.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852599262	423	53.72	19	419	6	207	5.8e-44	147.4	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
2852599264	281	97.21	1	281	5	283	1.8e-42	142.3	COG2175	Taurine dioxygenase, alpha-ketoglutarate-dependent	286
2852599265	424	90.74	2	422	28	409	1.5e-77	257.7	COG2124	Cytochrome P450	411
2852599266	64	95.59	1	61	1	65	1.8e-20	69.5	COG1141	Ferredoxin	68
2852599267	94	97.92	1	94	2	95	2.9e-24	81.8	COG5470	Uncharacterized conserved protein, DUF1330 family	96
2852599268	66	97.06	3	65	2	67	9.0e-15	51.3	COG1141	Ferredoxin	68
2852599269	400	93.59	2	399	26	419	2.0e-88	293.5	COG2124	Cytochrome P450	411
2852599270	272	76.92	2	269	2	221	7.9e-63	208.8	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
2852599271	272	89.16	1	270	1	255	4.1e-68	226.1	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
2852599272	304	75.25	2	290	23	244	8.7e-12	41.6	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852599273	551	82.27	9	134	17	132	3.8e-18	61.3	COG1545	Uncharacterized OB-fold protein, contains Zn-ribbon domain	140
2852599273	551	97.97	167	550	3	388	5.1e-34	114.2	COG0183	Acetyl-CoA acetyltransferase	392
2852599274	103	94.12	5	67	2	65	1.4e-13	47.1	COG1141	Ferredoxin	68
2852599275	422	88.68	27	400	46	421	2.5e-73	242.3	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
2852599277	290	96.95	4	290	7	292	7.7e-19	65	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852599278	130	93.46	11	130	6	105	7.8e-24	76.5	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
2852599279	380	80.26	38	369	59	302	5.5e-27	91.5	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
2852599280	364	80.26	16	358	59	302	4.8e-29	97.6	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
2852599281	332	20.55	2	92	6	87	1.5e-33	9.1	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852599281	332	64.16	94	329	136	391	1.5e-33	105.1	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852599282	395	97.74	2	395	8	397	3.0e-73	240.8	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852599283	255	90.57	2	255	10	249	5.2e-65	216	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2852599284	432	96.74	4	401	11	396	4.8e-79	262.7	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852599285	259	88.43	2	259	4	240	6.4e-52	173.3	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852599286	453	25.16	317	452	360	480	1.5e-117	64.9	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
2852599286	453	63.62	2	319	4	309	1.5e-117	323.5	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
2852599288	458	91.45	4	420	36	420	1.6e-72	241.2	COG2124	Cytochrome P450	411
2852599289	64	100	1	64	1	68	7.2e-17	58	COG1141	Ferredoxin	68
2852599290	286	98.51	2	278	3	266	3.1e-54	180.8	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852599291	232	97.76	2	231	6	267	1.3e-70	234.1	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852599292	495	98.33	19	494	3	473	0.0e+00	507.8	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2852599293	401	98.25	1	400	8	401	4.6e-81	269.3	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2852599294	391	70.92	285	388	41	140	4.2e-11	38.6	COG1545	Uncharacterized OB-fold protein, contains Zn-ribbon domain	140
2852599295	389	98.98	1	383	1	390	6.7e-80	265.5	COG0183	Acetyl-CoA acetyltransferase	392
2852599296	270	93.63	11	269	17	266	1.1e-80	267.1	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
2852599297	285	97.38	12	279	6	265	9.3e-72	237.8	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
2852599298	426	95.14	32	366	14	365	5.1e-64	213	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852599299	343	87.3	1	335	1	323	2.5e-67	224.1	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852599300	364	91.89	2	359	12	351	4.0e-59	197	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852599301	492	95.14	1	364	11	362	1.9e-75	250.6	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852599302	437	78.65	1	359	4	294	1.4e-61	205.1	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852599303	563	99.73	1	366	1	369	6.7e-76	252.1	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852599307	426	94.06	2	424	24	419	1.6e-83	277.3	COG2124	Cytochrome P450	411
2852599308	212	53.11	1	209	9	119	2.2e-17	61	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852599310	380	99.75	1	380	1	393	7.7e-64	212.6	COG0183	Acetyl-CoA acetyltransferase	392
2852599311	96	55.32	1	95	58	135	2.1e-08	30.3	COG1545	Uncharacterized OB-fold protein, contains Zn-ribbon domain	140
2852599312	141	18.9	2	42	7	37	6.5e-03	4.8	COG5517	3-phenylpropionate/cinnamic acid dioxygenase, small subunit	164
2852599312	141	36.59	48	131	88	147	6.5e-03	6.8	COG5517	3-phenylpropionate/cinnamic acid dioxygenase, small subunit	164
2852599313	266	91.7	4	259	4	246	4.7e-53	176.5	COG0300	Short-chain dehydrogenase	265
2852599314	173	92.47	7	143	4	138	3.9e-04	16.6	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2852599315	238	81.89	1	235	8	224	4.9e-55	183.2	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2852599316	512	90.67	18	509	42	556	2.0e-73	243.8	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2852599317	396	67.76	74	396	94	299	3.1e-12	43	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
2852599318	484	95.95	2	484	11	555	1.9e-100	331.5	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2852599321	331	92.79	1	330	12	307	4.5e-41	137.8	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
2852599322	219	76.72	16	219	52	229	1.7e-25	86.1	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	230
2852599323	238	96.55	7	238	6	229	1.1e-45	152	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	230
2852599324	140	54.82	1	131	13	103	5.1e-07	26.6	COG3467	Nitroimidazol reductase NimA or a related FMN-containing flavoprotein, pyridoxamine 5'-phosphate oxidase superfamily	166
2852599326	193	52.14	4	156	3	148	9.8e-13	44.5	COG3629	DNA-binding transcriptional activator of the SARP family	280
2852599327	335	97.2	1	331	4	315	1.8e-54	181.8	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2852599328	420	92.51	8	411	12	369	1.2e-38	129.1	COG4292	Low temperature requirement protein LtrA (function unknown)	387
2852599329	139	92.11	9	70	6	75	6.9e-04	16.6	COG4572	Cation transport regulator ChaB	76
2852599330	423	37.11	226	410	275	441	2.4e-17	34.8	COG2271	Sugar phosphate permease	448
2852599330	423	40.44	2	190	31	212	2.4e-17	29.9	COG2271	Sugar phosphate permease	448
2852599331	250	56.82	4	235	4	78	3.6e-15	52.9	COG0789	DNA-binding transcriptional regulator, MerR family	124
2852599332	267	94.01	3	266	10	260	1.9e-79	263	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
2852599333	293	92.01	17	292	11	275	3.6e-66	219.7	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
2852599334	400	91.53	1	400	14	359	3.8e-51	170.8	COG0687	Spermidine/putrescine-binding periplasmic protein	363
2852599335	349	98.3	7	346	4	350	2.0e-117	387.8	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2852599337	3073	67.92	1180	1330	17	124	1.1e-25	86.4	COG2030	Acyl dehydratase	159
2852599337	3073	99.66	1724	2589	4	871	0.0e+00	1296.7	COG4982	3-oxoacyl-ACP reductase domain of yeast-type FAS1	866
2852599337	3073	99.86	387	1091	2	717	0.0e+00	1049.9	COG4981	Enoyl reductase domain of yeast-type FAS1	717
2852599338	130	97.64	2	130	2	125	5.4e-36	120	COG0736	Phosphopantetheinyl transferase (holo-ACP synthase)	127
2852599339	448	99.04	1	443	4	417	5.7e-75	249.5	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2852599340	157	95.54	4	157	3	152	2.2e-61	202.8	COG1225	Peroxiredoxin	157
2852599343	88	9.2	5	83	449	508	2.9e-03	12.3	COG2433	Possible nuclease of RNase H fold, RuvC/YqgF family	652
2852599346	408	99.17	117	381	2	241	2.2e-54	181.2	COG1376	Lipoprotein-anchoring transpeptidase ErfK/SrfK	232
2852599348	215	96.2	1	183	6	182	1.1e-81	269.2	COG1949	Oligoribonuclease (3'-5' exoribonuclease)	184
2852599349	527	83.8	43	453	8	457	3.5e-61	204	COG0433	Archaeal DNA helicase HerA or a related bacterial ATPase, contains HAS-barrel and ATPase domains	520
2852599350	268	97.74	4	267	4	262	1.1e-82	273.8	COG0300	Short-chain dehydrogenase	265
2852599351	415	95.58	1	414	13	445	1.0e-109	362.8	COG2270	MFS-type transporter involved in bile tolerance, Atg22 family	438
2852599353	625	52.98	76	622	315	670	2.8e-68	227.1	COG1506	Dipeptidyl aminopeptidase/acylaminoacyl peptidase	620
2852599355	51	15.17	1	49	173	216	4.9e-02	9.5	COG1398	Fatty-acid desaturase	289
2852599356	205	91.39	1	203	5	195	2.2e-23	80.5	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852599357	517	97.15	2	517	6	516	0.0e+00	665.4	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component	526
2852599358	663	99.69	2	655	2	645	0.0e+00	842.2	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
2852599359	386	96.74	3	386	7	392	3.5e-120	398	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852599360	160	94.34	2	159	9	158	1.6e-44	147.3	COG2030	Acyl dehydratase	159
2852599361	271	96.84	9	270	2	277	2.2e-78	259.5	COG2301	Citrate lyase beta subunit	283
2852599362	367	98.04	18	361	7	357	9.3e-111	366.3	COG1071	TPP-dependent pyruvate or acetoin dehydrogenase subunit alpha	358
2852599363	353	99.38	31	352	2	323	7.5e-127	419	COG0022	Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component	324
2852599364	407	99.54	14	406	2	433	1.2e-102	340.6	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
2852599366	250	95.85	2	250	6	259	4.4e-59	196.2	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2852599367	400	96.46	7	399	11	391	2.6e-25	84.9	COG2814	Predicted arabinose efflux permease, MFS family	394
2852599377	567	80.46	260	507	27	236	5.2e-41	136.6	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
2852599377	567	93.4	28	250	7	204	4.0e-52	172.4	COG0560	Phosphoserine phosphatase	212
2852599378	782	96.54	2	772	26	807	0.0e+00	758.1	COG2937	Glycerol-3-phosphate O-acyltransferase	810
2852599379	668	93.08	59	342	19	287	8.2e-22	74.6	COG1276	Putative copper export protein	289
2852599379	668	98	357	665	3	296	4.3e-98	323.3	COG3336	Cytochrome c oxidase assembly factor CtaG	299
2852599380	244	60.57	3	240	42	210	4.7e-10	36.4	COG0500	SAM-dependent methyltransferase	257
2852599381	536	85.03	2	398	59	467	7.6e-87	288.4	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
2852599382	156	76.02	1	151	4	133	2.8e-26	89.3	COG0629	Single-stranded DNA-binding protein	167
2852599383	558	99.25	3	539	3	533	0.0e+00	587.9	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
2852599384	1615	96.67	29	1609	53	1592	0.0e+00	1988.8	COG2902	NAD-specific glutamate dehydrogenase	1592
2852599385	135	94.96	2	135	5	136	4.0e-26	87.9	COG0824	Acyl-CoA thioesterase FadM	137
2852599387	525	96.91	13	515	2	502	7.6e-121	401.2	COG0366	Glycosidase	505
2852599388	131	93.98	1	131	4	128	5.7e-48	158.8	COG2346	Truncated hemoglobin YjbI	133
2852599389	218	91.61	60	203	1	142	6.3e-33	109.8	COG1403	5-methylcytosine-specific restriction endonuclease McrA	146
2852599392	113	30.97	3	98	75	122	3.3e-06	23.3	COG1403	5-methylcytosine-specific restriction endonuclease McrA	146
2852599393	861	99.19	2	860	3	862	0.0e+00	684.9	COG0308	Aminopeptidase N	859
2852599396	203	66.51	5	190	6	146	3.4e-08	28	COG3531	Predicted protein-disulfide isomerase , contains CxxC motif	212
2852599397	212	56.34	1	169	2	121	9.9e-27	90.6	COG0655	Multimeric flavodoxin WrbA	207
2852599398	468	95.98	15	467	12	441	2.6e-75	249.8	COG1457	Purine-cytosine permease or related protein	442
2852599399	146	80.39	1	143	7	129	2.7e-25	85.6	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
2852599400	317	85.85	1	305	7	285	1.4e-52	175.3	COG3491	Isopenicillin N synthase and related dioxygenases	322
2852599401	162	98.68	4	154	1	149	3.1e-56	185.7	COG0698	Ribose 5-phosphate isomerase RpiB	151
2852599402	264	100	1	264	1	274	4.4e-59	196.8	COG0266	Formamidopyrimidine-DNA glycosylase	273
2852599404	96	97.92	1	96	3	96	3.1e-29	97.5	COG5470	Uncharacterized conserved protein, DUF1330 family	96
2852599407	402	51.61	83	395	242	514	6.3e-77	255.5	COG0464	AAA+-type ATPase, SpoVK/Ycf46/Vps4 family	494
2852599408	343	66.03	2	304	103	345	4.0e-19	66.1	COG0457	Tetratricopeptide (TPR) repeat	291
2852599411	465	97.99	2	444	3	441	4.4e-126	417.4	COG0544	FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)	441
2852599412	203	88.5	2	195	18	194	6.5e-75	247.7	COG0740	ATP-dependent protease ClpP, protease subunit	200
2852599413	215	96.5	14	215	5	197	1.5e-75	249.8	COG0740	ATP-dependent protease ClpP, protease subunit	200
2852599414	294	96.33	4	294	8	296	9.3e-103	339.9	COG2040	Homocysteine/selenocysteine methylase (S-methylmethionine-dependent)	300
2852599415	426	98.78	14	424	1	404	0.0e+00	674.8	COG1219	ATP-dependent protease Clp, ATPase subunit	408
2852599417	435	98.04	1	431	4	403	1.0e-53	175	COG1819	UDP:flavonoid glycosyltransferase YjiC, YdhE family	406
2852599418	315	96.95	22	307	5	290	1.1e-33	113.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852599419	270	92.51	1	262	20	266	1.8e-91	302.5	COG1526	Formate dehydrogenase assembly factor FdhD	266
2852599420	785	97.41	29	775	20	808	1.5e-130	431.3	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2852599421	366	97.44	1	363	1	342	4.7e-66	219.8	COG0673	Predicted dehydrogenase	342
2852599422	725	95.86	2	725	30	723	0.0e+00	1082.1	COG3968	Glutamine synthetase type III	724
2852599423	497	99.16	5	484	3	477	0.0e+00	507.4	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2852599424	291	94.6	1	288	13	275	9.8e-55	182.3	COG1082	Sugar phosphate isomerase/epimerase	274
2852599425	336	99.72	1	330	1	350	2.5e-58	194.5	COG0673	Predicted dehydrogenase	342
2852599426	300	91.73	6	290	4	258	3.9e-36	121.2	COG1082	Sugar phosphate isomerase/epimerase	274
2852599427	643	99.35	13	638	3	616	0.0e+00	852.1	COG3962	TPP-dependent trihydroxycyclohexane-1,2-dione (THcHDO) dehydratase, myo-inositol metabolism	617
2852599428	286	95.56	2	272	11	268	2.2e-76	252.9	COG3718	5-deoxy-D-glucuronate isomerase	270
2852599429	293	93.31	21	293	9	259	1.0e-08	30.5	COG1830	Fructose-bisphosphate aldolase class Ia, DhnA family	265
2852599430	323	99.37	8	317	1	314	1.5e-70	234.1	COG0524	Sugar or nucleoside kinase, ribokinase family	311
2852599431	243	97.49	5	240	5	237	1.5e-63	210.8	COG2188	DNA-binding transcriptional regulator, GntR family	236
2852599432	258	98.85	3	258	2	258	9.5e-71	234.7	COG3622	Hydroxypyruvate isomerase	260
2852599433	328	96.02	1	326	11	324	2.9e-43	144.2	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
2852599434	352	96.24	24	352	8	314	5.7e-70	232	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
2852599435	370	51.1	15	298	7	262	1.3e-80	267.4	COG1129	ABC-type sugar transport system, ATPase component	500
2852599436	485	14.89	85	188	131	190	5.4e-25	25.5	COG3391	DNA-binding beta-propeller fold protein YncE	381
2852599436	485	66.5	135	485	16	283	5.4e-25	73.3	COG3391	DNA-binding beta-propeller fold protein YncE	381
2852599437	880	71.25	790	865	16	72	1.0e-15	52.3	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2852599440	533	11.27	355	529	496	559	1.2e-47	51.9	COG2303	Choline dehydrogenase or related flavoprotein	542
2852599440	533	50.88	1	283	5	293	1.2e-47	106.3	COG2303	Choline dehydrogenase or related flavoprotein	542
2852599441	320	97.15	1	320	2	342	3.2e-67	223.8	COG0673	Predicted dehydrogenase	342
2852599442	290	93.88	6	286	14	274	7.0e-40	133.5	COG1082	Sugar phosphate isomerase/epimerase	274
2852599443	334	98.86	1	331	4	350	5.6e-63	209.8	COG0673	Predicted dehydrogenase	342
2852599444	387	86.96	51	367	27	286	4.9e-51	169.9	COG5285	Ectoine hydroxylase-related dioxygenase, phytanoyl-CoA dioxygenase (PhyH) family	299
2852599446	334	96.33	9	334	4	318	2.5e-33	111.5	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
2852599447	649	96.86	242	631	3	372	7.1e-87	288.1	COG0674	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, alpha subunit	365
2852599447	649	99.02	19	233	2	203	6.3e-41	136.1	COG1014	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, gamma subunit	203
2852599448	358	74.25	24	337	4	225	5.7e-82	271.6	COG1013	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, beta subunit	294
2852599449	196	96.39	3	193	4	190	4.0e-48	159.7	COG0746	Molybdopterin-guanine dinucleotide biosynthesis protein A	192
2852599453	363	61.32	1	278	2	242	2.3e-39	132.2	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2852599454	176	85.82	42	176	17	137	5.7e-30	99.6	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
2852599455	130	83.33	4	121	10	109	2.3e-29	97.6	COG1733	DNA-binding transcriptional regulator, HxlR family	120
2852599456	656	98.96	4	646	5	669	2.3e-75	250.5	COG1506	Dipeptidyl aminopeptidase/acylaminoacyl peptidase	620
2852599457	419	99.74	3	418	2	382	0.0e+00	480.6	COG3268	Uncharacterized conserved protein, related to short-chain dehydrogenases	382
2852599458	199	63.51	1	199	17	197	2.6e-16	56.4	COG5403	Uncharacterized protein	285
2852599459	886	99.66	12	886	2	881	0.0e+00	1132.9	COG0525	Valyl-tRNA synthetase	877
2852599460	467	99.07	8	467	3	427	0.0e+00	442.8	COG0285	Folylpolyglutamate synthase/Dihydropteroate synthase	427
2852599461	129	43.78	15	114	63	143	4.3e-03	12.8	COG1268	Biotin transporter BioY	184
2852599462	136	98.52	1	136	2	134	2.3e-55	182.5	COG0105	Nucleoside diphosphate kinase	135
2852599463	936	89.16	289	790	3	438	0.0e+00	520.5	COG1530	Ribonuclease G or E	487
2852599464	103	99.03	3	103	1	102	3.3e-36	120.3	COG0261	Ribosomal protein L21	103
2852599465	88	95.4	1	85	1	83	3.4e-40	132.1	COG0211	Ribosomal protein L27	87
2852599466	479	92.01	2	365	2	335	2.4e-128	424.4	COG0536	GTPase involved in cell partioning and DNA repair	369
2852599467	367	99.19	7	367	3	369	8.5e-126	416.3	COG0263	Glutamate 5-kinase	369
2852599469	278	93.77	5	275	13	253	6.0e-52	169.5	COG0846	NAD-dependent protein deacetylase, SIR2 family	250
2852599470	184	73.29	7	146	39	145	2.6e-27	91.5	COG0071	Molecular chaperone IbpA, HSP20 family	146
2852599472	188	15.44	1	175	801	951	9.3e-28	92.8	COG3383	Predicted molibdopterin-dependent oxidoreductase YjgC	978
2852599473	621	76.05	23	618	53	668	9.1e-119	394	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2852599474	179	95.15	1	179	4	199	5.9e-20	67.4	COG1335	Nicotinamidase-related amidase	205
2852599475	680	95.68	10	299	2	267	1.2e-44	148.4	COG0388	Predicted amidohydrolase	274
2852599475	680	99.27	336	656	2	273	5.0e-84	278	COG0171	NH3-dependent NAD+ synthetase	268
2852599477	179	88.27	20	179	21	178	4.4e-30	100.8	COG1881	Uncharacterized conserved protein, phosphatidylethanolamine-binding protein (PEBP) family	174
2852599478	200	61.97	5	195	11	199	2.1e-15	52.3	COG0053	Divalent metal cation (Fe/Co/Zn/Cd) transporter	304
2852599479	101	72.03	4	97	21	105	2.5e-15	53.2	COG0640	DNA-binding transcriptional regulator, ArsR family	110
2852599480	273	97.74	15	262	7	265	7.1e-58	192.3	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2852599481	293	97.78	4	285	2	310	3.1e-56	185.2	COG0524	Sugar or nucleoside kinase, ribokinase family	311
2852599482	415	99.28	11	414	3	416	0.0e+00	563.2	COG0014	Gamma-glutamyl phosphate reductase	417
2852599483	291	80.3	3	285	9	273	5.6e-66	219.1	COG0714	MoxR-like ATPase	329
2852599484	481	99.75	1	481	1	396	0.0e+00	474.6	COG3552	Uncharacterized conserved protein, contains von Willebrand factor type A (vWA) domain	395
2852599485	213	98.49	3	203	3	198	6.2e-64	211.9	COG1057	Nicotinic acid mononucleotide adenylyltransferase	197
2852599486	122	95.65	5	119	3	112	2.7e-41	136.3	COG0799	Ribosomal silencing factor RsfS, regulates association of 30S and 50S subunits	115
2852599487	222	97.13	2	213	3	205	2.6e-55	183.7	COG0406	Broad specificity phosphatase PhoE	208
2852599489	279	98.94	1	278	1	279	7.1e-63	208.7	COG1307	Fatty acid-binding protein DegV (function unknown)	282
2852599490	838	69.29	439	703	92	346	9.8e-37	122.5	COG2208	Serine phosphatase RsbU, regulator of sigma subunit	367
2852599490	838	91.1	711	838	8	140	2.2e-17	58.1	COG2172	Anti-sigma regulatory factor (Ser/Thr protein kinase)	146
2852599491	112	58.12	3	95	7	74	4.6e-10	35.6	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
2852599492	106	69.49	7	101	21	102	1.2e-16	57.4	COG0640	DNA-binding transcriptional regulator, ArsR family	110
2852599493	158	92.36	1	155	5	149	2.8e-06	22.1	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
2852599495	872	73.75	797	866	15	73	1.1e-14	48.8	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2852599496	348	98.29	4	348	3	346	3.2e-62	206.8	COG3804	Uncharacterized protein	350
2852599497	498	83.1	2	495	4	480	2.3e-128	425.4	COG3263	NhaP-type Na+/H+ and K+/H+ antiporter with C-terminal TrkAC and CorC domains	574
2852599498	258	93.3	29	246	1	209	1.4e-44	148.5	COG0569	Trk K+ transport system, NAD-binding component	225
2852599499	268	97.76	6	267	5	266	1.7e-60	201.1	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852599501	189	75.89	51	188	31	137	1.9e-10	36.7	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
2852599502	163	84.32	3	160	12	167	4.5e-41	136.7	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
2852599503	224	57.66	12	155	12	90	1.9e-19	65.4	COG1695	DNA-binding transcriptional regulator, PadR family	138
2852599505	379	55.85	7	346	16	225	1.2e-47	157.3	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
2852599506	96	8.91	6	84	172	238	1.4e-02	9.9	COG0068	Hydrogenase maturation factor HypF (carbamoyltransferase)	750
2852599507	265	77.99	1	236	5	213	5.2e-34	114.3	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852599509	311	87.11	6	306	41	317	9.3e-70	231.9	COG0657	Acetyl esterase/lipase	312
2852599510	287	81.72	7	276	5	223	2.4e-44	148.2	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852599512	519	97.01	1	518	11	561	3.2e-123	408.3	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2852599513	385	96.99	2	385	6	392	3.8e-109	361.7	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852599514	628	95.29	120	585	5	429	1.2e-87	291	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
2852599515	295	79.1	3	259	2	213	2.8e-53	177.5	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852599517	225	68.9	4	189	4	147	1.4e-11	41	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852599520	311	90.88	1	307	13	301	1.8e-79	264	COG0657	Acetyl esterase/lipase	312
2852599521	279	93.5	12	243	2	231	1.4e-60	200.4	COG1414	DNA-binding transcriptional regulator, IclR family	246
2852599522	488	72.44	15	488	4	413	1.3e-26	88.1	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
2852599523	302	42.47	7	122	82	143	1.1e-07	12.9	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2852599523	302	96.58	142	267	2	142	1.1e-07	16.3	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2852599524	393	88.47	2	367	26	378	1.7e-31	105.3	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852599525	89	73.79	1	89	17	92	5.2e-15	51.6	COG0633	Ferredoxin	102
2852599526	539	98.65	3	493	5	444	1.6e-110	365.2	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
2852599527	267	98.13	2	264	5	267	6.3e-64	212.4	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852599528	277	98.88	3	275	2	266	2.1e-65	217.3	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852599529	292	96.27	15	290	11	294	1.4e-43	145.8	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852599531	352	97.44	14	348	3	307	2.6e-71	235.8	COG2421	Acetamidase/formamidase	305
2852599532	141	87.5	7	132	13	131	3.4e-25	84.7	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
2852599533	301	73.42	4	252	11	231	9.0e-52	171.5	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
2852599539	220	68.66	116	219	31	122	2.4e-06	23.2	COG3255	Putative sterol carrier protein	134
2852599539	220	81.67	1	108	6	103	6.3e-24	79.9	COG1733	DNA-binding transcriptional regulator, HxlR family	120
2852599541	298	97.46	1	268	2	270	4.7e-55	183.2	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
2852599543	267	84.81	89	267	25	158	7.0e-33	110.2	COG1555	DNA uptake protein ComE and related DNA-binding proteins	149
2852599544	514	97.05	4	502	8	468	3.3e-49	164.1	COG0658	Predicted membrane metal-binding protein	453
2852599545	320	94.31	4	319	18	332	2.9e-65	216.9	COG1466	DNA polymerase III, delta subunit	334
2852599546	86	95.45	1	86	2	85	1.4e-30	102.1	COG0268	Ribosomal protein S20	88
2852599547	563	97.13	31	517	8	481	0.0e+00	722.6	COG2308	Uncharacterized conserved protein, circularly permuted ATPgrasp superfamily	488
2852599548	325	100	1	307	1	313	1.1e-100	333.5	COG2307	Uncharacterized conserved protein, Alpha-E superfamily	313
2852599549	279	92.01	1	279	10	320	5.4e-59	196.9	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
2852599550	160	85.71	12	143	15	128	7.1e-25	83.8	COG1846	DNA-binding transcriptional regulator, MarR family	126
2852599552	285	60.06	5	284	18	223	3.8e-47	157.4	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852599554	286	99.67	1	277	1	302	4.8e-52	171.2	COG1234	Ribonuclease BN, tRNA processing enzyme	292
2852599555	386	90.96	17	378	3	344	2.4e-50	168.1	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
2852599556	456	99.33	13	455	3	445	3.1e-118	391.6	COG0174	Glutamine synthetase	443
2852599557	247	94.38	4	245	13	247	2.9e-50	167.3	COG1402	 Creatinine amidohydrolase/Fe(II)-dependent formamide hydrolase involved in riboflavin and F420 biosynthesis	250
2852599558	243	72.73	13	236	13	164	1.3e-18	64.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852599559	340	97.19	7	327	3	313	1.9e-97	322.3	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2852599560	143	92.02	4	121	14	163	7.4e-25	84.4	COG0517	CBS domain	117
2852599561	201	52.47	19	198	69	153	4.0e-05	20.4	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2852599563	579	95.02	1	573	29	601	0.0e+00	920.7	COG0481	Translation elongation factor EF-4, membrane-bound GTPase	603
2852599565	237	30.38	6	81	7	30	1.2e-03	15.8	COG4238	Outer membrane murein-binding lipoprotein Lpp	78
2852599566	103	16.28	5	103	23	43	3.1e-05	19	COG2149	Uncharacterized membrane protein YidH, DUF202 family	120
2852599567	119	92.25	2	117	10	128	3.0e-38	127.1	COG2149	Uncharacterized membrane protein YidH, DUF202 family	120
2852599570	676	97.44	33	666	7	614	0.0e+00	548.5	COG3387	Glucoamylase (glucan-1,4-alpha-glucosidase), GH15 family	612
2852599571	414	90.08	9	394	2	355	2.9e-65	217.4	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2852599573	342	95.7	2	342	14	347	3.3e-111	368	COG1613	ABC-type sulfate transport system, periplasmic component	348
2852599574	294	95.62	30	291	12	273	9.3e-92	303	COG0555	ABC-type sulfate transport system, permease component	274
2852599575	270	91.29	1	270	18	279	2.2e-107	354.8	COG4208	ABC-type sulfate transport system, permease component	287
2852599576	352	97.71	3	333	3	344	1.5e-121	402.2	COG1118	ABC-type sulfate/molybdate transport systems, ATPase component	345
2852599577	483	97.08	10	425	9	341	7.5e-83	274.7	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852599578	234	99.2	1	233	3	251	3.5e-41	137.8	COG2138	Sirohydrochlorin ferrochelatase	245
2852599579	234	88.43	1	234	13	249	7.1e-63	208.8	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
2852599580	557	97.28	21	557	5	504	0.0e+00	546.1	COG0155	Sulfite reductase, beta subunit (hemoprotein)	510
2852599582	390	90.48	2	390	35	414	2.6e-113	375.1	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
2852599583	171	89.78	1	171	15	181	1.6e-37	125.4	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2852599585	607	89.86	32	597	57	588	1.6e-129	429.4	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2852599586	576	94.59	2	568	29	588	2.8e-125	415.5	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2852599587	444	91.86	3	443	31	459	4.9e-86	286	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
2852599590	496	99.16	12	487	2	476	0.0e+00	576.1	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2852599591	286	87.76	3	277	17	317	1.5e-17	56.2	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852599592	127	60.29	10	121	46	127	5.3e-03	13.2	COG3631	Ketosteroid isomerase-related protein	133
2852599593	247	75	123	243	21	119	6.9e-17	57.1	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2852599594	297	84.7	3	278	27	264	4.2e-39	130.9	COG3000	Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily	271
2852599595	101	51.89	2	89	15	69	3.7e-04	16.8	COG2329	Heme-degrading monooxygenase HmoA and related ABM domain proteins	105
2852599596	851	15.55	538	713	728	889	1.1e-116	21.2	COG4581	Superfamily II RNA helicase	1041
2852599596	851	17.27	228	414	369	548	1.1e-116	166.7	COG4581	Superfamily II RNA helicase	1041
2852599596	851	19.96	12	244	108	315	1.1e-116	197.9	COG4581	Superfamily II RNA helicase	1041
2852599597	528	97.79	1	524	7	536	0.0e+00	722.6	COG1021	Non-ribosomal peptide synthetase component E (peptide arylation enzyme)	542
2852599598	1159	91.89	9	81	2	69	5.1e-27	84.4	COG3433	Aryl carrier domain	74
2852599598	1159	99.69	311	957	3	648	0.0e+00	436.3	COG1020	Non-ribosomal peptide synthetase component F	642
2852599599	248	89.75	20	248	11	229	7.4e-70	230.9	COG3208	Surfactin synthase thioesterase subunit	244
2852599600	436	36.06	2	436	6	433	0.0e+00	588.8	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
2852599601	968	55.41	887	949	14	54	6.1e-03	11.3	COG3433	Aryl carrier domain	74
2852599601	968	66.26	644	832	9	171	1.4e-09	33.5	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
2852599601	968	88.82	90	365	3	304	3.4e-32	106.2	COG0331	Malonyl CoA-acyl carrier protein transacylase	310
2852599602	1681	10.49	1497	1556	555	622	0.0e+00	11.8	COG1020	Non-ribosomal peptide synthetase component F	642
2852599602	1681	25.06	1057	1209	33	142	7.1e-04	7.4	COG4908	Uncharacterized protein, contains a NRPS condensation (elongation) domain	439
2852599602	1681	28.25	43	197	33	156	7.1e-04	4.9	COG4908	Uncharacterized protein, contains a NRPS condensation (elongation) domain	439
2852599602	1681	34.26	1277	1501	4	225	0.0e+00	89.6	COG1020	Non-ribosomal peptide synthetase component F	642
2852599602	1681	75.68	1576	1643	6	61	3.0e-05	16.3	COG3433	Aryl carrier domain	74
2852599602	1681	87.65	965	1037	7	77	2.3e-05	16	COG0236	Acyl carrier protein	80
2852599602	1681	99.54	245	880	2	646	0.0e+00	483.8	COG1020	Non-ribosomal peptide synthetase component F	642
2852599603	1431	74.32	938	1010	6	60	7.7e-06	19.3	COG3433	Aryl carrier domain	74
2852599603	1431	98.77	223	853	9	648	4.9e-111	368.9	COG1020	Non-ribosomal peptide synthetase component F	642
2852599604	428	36.24	81	425	71	228	1.4e-10	36.2	COG3486	Lysine/ornithine N-monooxygenase	436
2852599605	71	98.59	1	71	1	70	8.5e-36	118	COG3251	Uncharacterized conserved protein YbdZ, MbtH family	71
2852599606	226	92.35	10	212	9	177	6.7e-08	27.1	COG3371	Uncharacterized membrane protein	181
2852599607	104	100	12	97	1	84	7.6e-24	80	COG5450	Transcription regulator of the Arc/MetJ class	84
2852599608	343	98.84	1	343	3	343	6.7e-106	351	COG1420	Transcriptional regulator of heat shock response	346
2852599609	380	99.22	1	379	3	384	3.5e-126	417.9	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
2852599610	247	97.97	2	243	5	245	3.5e-62	206.1	COG1385	16S rRNA U1498 N3-methylase RsmE	246
2852599611	344	92.06	4	336	19	331	0.0e+00	439.3	COG1702	Phosphate starvation-inducible protein PhoH, predicted ATPase	348
2852599612	178	96.1	1	157	4	151	1.3e-46	154.3	COG0319	ssRNA-specific RNase YbeY, 16S rRNA maturation enzyme	153
2852599613	429	98.4	2	428	5	435	1.1e-105	350.2	COG1253	Hemolysin or related protein, contains CBS domains	429
2852599614	105	37.96	1	84	32	83	1.2e-02	11.8	COG0295	Cytidine deaminase	134
2852599615	299	98.66	1	299	2	295	1.1e-111	369.1	COG1159	GTPase Era, involved in 16S rRNA processing	298
2852599616	181	35.81	10	139	84	160	3.0e-05	20.3	COG2340	Uncharacterized conserved protein YkwD, contains CAP (CSP/antigen 5/PR1) domain	207
2852599617	512	98.54	7	479	7	480	1.7e-125	416	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
2852599618	280	97.62	1	250	3	248	1.6e-68	227.1	COG1381	Recombinational DNA repair protein (RecF pathway)	251
2852599619	293	95.63	44	292	12	252	1.0e-92	306.3	COG0020	Undecaprenyl pyrophosphate synthase	245
2852599621	132	87.59	3	132	15	141	2.9e-43	143.5	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
2852599622	119	76.27	21	119	17	106	8.3e-16	54.8	COG0640	DNA-binding transcriptional regulator, ArsR family	110
2852599623	463	14.74	226	315	266	349	0.0e+00	79.2	COG0423	Glycyl-tRNA synthetase (class II)	558
2852599623	463	25.26	307	463	421	564	0.0e+00	192.4	COG0423	Glycyl-tRNA synthetase (class II)	558
2852599623	463	39.3	2	231	5	228	0.0e+00	324.5	COG0423	Glycyl-tRNA synthetase (class II)	558
2852599624	238	75	19	197	18	146	1.2e-15	53.8	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2852599625	674	99.85	11	673	2	676	0.0e+00	725.3	COG1505	Prolyl oligopeptidase PreP, S9A serine peptidase family	648
2852599626	664	57.74	282	450	24	161	4.8e-03	10.5	COG1579	Predicted  nucleic acid-binding protein, contains Zn-ribbon domain	239
2852599627	418	93.59	9	417	19	412	5.9e-111	368	COG0232	dGTP triphosphohydrolase	412
2852599628	633	99.83	4	623	1	595	0.0e+00	515.1	COG0358	DNA primase (bacterial type)	568
2852599632	257	69.4	2	245	57	217	7.3e-12	41.3	COG0671	Membrane-associated phospholipid phosphatase	232
2852599633	129	95.59	1	124	5	134	1.7e-18	62.9	COG3631	Ketosteroid isomerase-related protein	133
2852599635	640	88.97	3	441	42	396	1.1e-51	172.2	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852599636	243	98.27	11	243	3	229	8.9e-39	129.6	COG1814	Predicted Fe2+/Mn2+ transporter, VIT1/CCC1 family	229
2852599637	403	95.7	2	377	10	387	1.6e-32	108.7	COG2814	Predicted arabinose efflux permease, MFS family	394
2852599638	145	93.98	8	137	7	131	9.5e-20	67.3	COG1846	DNA-binding transcriptional regulator, MarR family	126
2852599639	679	89.03	232	446	5	215	1.9e-84	121.1	COG1122	Energy-coupling factor transporter ATP-binding protein EcfA2	235
2852599639	679	91.98	458	676	3	220	1.9e-84	155.4	COG1122	Energy-coupling factor transporter ATP-binding protein EcfA2	235
2852599640	275	97.4	11	271	4	265	1.2e-38	129.1	COG0619	Energy-coupling factor transporter transmembrane protein EcfT	252
2852599641	1053	75.41	14	229	48	231	8.1e-42	138.2	COG2114	Adenylate cyclase, class 3	227
2852599644	439	97.74	8	439	8	440	1.1e-51	172.9	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2852599645	275	98.23	1	275	6	283	2.8e-79	262.9	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
2852599646	290	95.97	1	287	7	292	1.4e-84	280.3	COG1175	ABC-type sugar transport system, permease component	295
2852599647	505	99.34	15	499	3	455	3.9e-112	371.6	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
2852599648	457	98.46	5	453	6	454	3.5e-53	177.2	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
2852599649	280	65.59	107	260	61	182	6.1e-13	44.8	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
2852599650	119	26.24	1	103	5	73	3.7e-21	73	COG2214	Curved DNA-binding protein CbpA, contains a DnaJ-like domain	237
2852599654	385	96.76	8	384	9	366	2.0e-63	210.5	COG0387	Ca2+/H+ antiporter	368
2852599656	271	51.88	2	88	64	132	4.3e-05	2.6	COG2009	Succinate dehydrogenase/fumarate reductase, cytochrome b subunit	132
2852599656	271	72.93	99	221	22	118	4.3e-05	18	COG2009	Succinate dehydrogenase/fumarate reductase, cytochrome b subunit	132
2852599657	145	36.11	3	144	7	123	1.9e-05	20.8	COG3115	Cell division protein ZipA, interacts with FtsZ	324
2852599658	59	22.58	1	54	24	65	2.2e-03	13.8	COG3247	Uncharacterized membrane protein HdeD, DUF308 family	185
2852599659	57	77.61	1	57	6	57	1.8e-11	40.4	COG3237	Uncharacterized conserved protein YjbJ, UPF0337 family	67
2852599661	242	89.95	2	240	11	198	3.9e-12	43.5	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852599663	568	67.87	7	357	2	320	7.7e-62	206	COG0515	Serine/threonine protein kinase	384
2852599665	204	9.32	9	196	233	265	4.3e-03	12.3	COG0306	Phosphate/sulfate permease	326
2852599667	444	50.24	22	185	41	143	2.0e-04	16.6	COG3642	tRNA A-37 threonylcarbamoyl transferase component Bud32	204
2852599670	950	98.83	16	950	6	936	0.0e+00	991.7	COG2409	Uncharacterized membrane protein YdfJ, MMPL/SSD domain	937
2852599671	88	29	5	73	137	194	2.3e-10	36.8	COG4430	Uncharacterized conserved protein YdeI, YjbR/CyaY-like superfamily, DUF1801 family	200
2852599672	125	15.38	89	123	98	115	1.1e-02	4.7	COG3462	Uncharacterized membrane protein	117
2852599672	125	39.32	2	68	7	52	1.1e-02	5.8	COG3462	Uncharacterized membrane protein	117
2852599673	322	94.38	1	306	12	313	1.0e-78	260.7	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2852599674	463	63.43	225	456	35	230	8.1e-09	27.2	COG3386	Sugar lactone lactonase YvrE	307
2852599675	206	94.66	8	206	8	202	6.0e-33	110.5	COG1335	Nicotinamidase-related amidase	205
2852599681	246	98.88	2	244	2	266	6.8e-63	209.1	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852599682	541	99.09	1	532	3	549	0.0e+00	643.5	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
2852599683	293	95.3	1	286	13	296	4.7e-99	327.5	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2852599684	322	99.06	9	322	2	316	1.5e-111	369.2	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2852599685	511	94.98	3	505	12	560	1.9e-122	406.3	COG0747	ABC-type transport system, periplasmic component	556
2852599688	247	99.25	3	246	2	267	4.5e-69	229.3	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852599689	361	97.71	7	360	4	345	8.0e-66	218.4	COG3804	Uncharacterized protein	350
2852599691	579	84.46	4	471	8	344	1.7e-36	122.4	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852599693	208	57.54	1	206	11	197	1.5e-23	78.2	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
2852599695	391	51.44	189	388	4	200	2.1e-18	10.6	COG0477	MFS family permease	338
2852599695	391	59.27	1	220	19	245	2.1e-18	56.1	COG0477	MFS family permease	338
2852599696	308	95.77	1	303	15	331	1.3e-61	203.7	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2852599697	148	77.1	14	144	19	119	9.4e-19	63.8	COG1917	Cupin domain protein related to quercetin dioxygenase	131
2852599698	319	96.31	1	318	9	321	7.4e-88	291	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
2852599699	921	71.25	852	917	14	70	2.3e-17	57.4	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2852599700	936	71.25	856	927	14	70	1.0e-18	61.9	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2852599701	217	41.26	20	181	38	129	1.8e-05	20.9	COG1418	HD superfamily phosphodieaserase, includes HD domain of RNase Y	222
2852599702	155	84.08	1	147	15	146	8.3e-06	22.2	COG0783	DNA-binding ferritin-like protein (oxidative damage protectant)	156
2852599703	487	95.21	1	485	13	489	0.0e+00	622.3	COG0753	Catalase	496
2852599704	186	90.32	1	181	10	177	1.1e-41	138.9	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2852599705	558	36.4	1	207	2	203	3.7e-86	141.5	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
2852599705	558	63.42	213	558	183	534	3.7e-86	143.1	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
2852599706	320	96.62	1	320	9	322	1.6e-92	306.3	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
2852599708	328	84.33	11	292	2	227	2.3e-46	154.9	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852599709	222	80.86	3	219	6	174	6.1e-14	49.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852599711	209	79.23	6	208	19	224	2.6e-37	125	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2852599712	362	99.45	3	361	2	365	0.0e+00	436.3	COG1062	Zn-dependent alcohol dehydrogenase	366
2852599713	256	92.57	1	255	9	257	2.1e-61	204.1	COG3384	Aromatic ring-opening dioxygenase, catalytic subunit, LigB family	268
2852599714	356	43.85	105	305	59	165	1.2e-15	53.4	COG2227	2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase	243
2852599715	309	95.67	4	309	10	296	1.4e-50	168.5	COG2040	Homocysteine/selenocysteine methylase (S-methylmethionine-dependent)	300
2852599716	274	78.22	2	268	61	376	5.1e-26	80.4	COG1680	CubicO group peptidase, beta-lactamase class C family	390
2852599718	304	97.02	5	302	3	295	7.6e-75	247.9	COG1597	Diacylglycerol kinase family enzyme	301
2852599719	540	94.88	70	540	23	467	5.9e-72	239.3	COG0277	FAD/FMN-containing dehydrogenase	459
2852599720	192	81.82	6	190	17	187	6.8e-16	55.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852599721	512	94.23	12	512	2	507	0.0e+00	454.6	COG0578	Glycerol-3-phosphate dehydrogenase	532
2852599722	504	96.32	11	465	6	450	0.0e+00	512.7	COG1113	L-asparagine transporter and related permeases	462
2852599723	353	97.84	47	352	3	228	1.5e-56	185	COG1814	Predicted Fe2+/Mn2+ transporter, VIT1/CCC1 family	229
2852599724	261	91.86	4	259	23	293	1.6e-26	90	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852599725	473	88.4	9	473	47	511	0.0e+00	548.1	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component	526
2852599726	398	97.1	1	398	12	413	1.2e-125	415.9	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
2852599727	416	99.28	10	416	3	413	5.2e-128	423.7	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
2852599728	99	97.53	3	82	2	80	1.6e-25	85.2	COG0236	Acyl carrier protein	80
2852599729	310	97.35	4	309	3	333	7.2e-54	179.2	COG0331	Malonyl CoA-acyl carrier protein transacylase	310
2852599730	428	94.85	3	401	19	423	5.7e-65	216.4	COG2508	DNA-binding transcriptional regulator, PucR family	421
2852599731	929	99.1	29	923	3	881	0.0e+00	1439.6	COG2609	Pyruvate dehydrogenase complex, dehydrogenase (E1) component	887
2852599734	154	96.82	1	153	4	155	2.3e-36	121.3	COG1225	Peroxiredoxin	157
2852599738	131	42.12	4	130	11	125	1.5e-10	37	COG2514	Catechol-2,3-dioxygenase	265
2852599740	275	87	4	275	39	299	4.3e-89	295.1	COG3662	Uncharacterized conserved protein, DUF2236 family	300
2852599741	320	95.62	6	315	8	313	3.9e-90	298.3	COG1270	Cobalamin biosynthesis protein CobD/CbiB	320
2852599742	272	97.24	1	250	5	251	2.0e-66	220.1	COG3346	Cytochrome oxidase assembly protein ShyY1	252
2852599743	164	95.27	3	154	4	144	6.8e-37	123.2	COG0394	Protein-tyrosine-phosphatase	139
2852599744	225	97.3	11	225	5	220	1.6e-42	142.3	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
2852599746	375	32.68	291	374	77	159	2.1e-70	35.9	COG0327	Putative GTP cyclohydrolase 1 type 2, NIF3 family	250
2852599746	375	79.92	3	315	3	205	2.1e-70	203	COG0327	Putative GTP cyclohydrolase 1 type 2, NIF3 family	250
2852599747	245	96.65	3	244	5	235	1.1e-63	211.1	COG1579	Predicted  nucleic acid-binding protein, contains Zn-ribbon domain	239
2852599748	366	94.87	1	148	3	150	7.0e-37	122.3	COG0328	Ribonuclease HI	154
2852599748	366	96.17	161	365	3	203	3.7e-60	199.7	COG0406	Broad specificity phosphatase PhoE	208
2852599749	193	62.31	14	155	4	84	3.1e-16	56.6	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2852599750	319	97.72	2	305	3	302	1.5e-47	158.3	COG0492	Thioredoxin reductase	305
2852599751	207	64.16	1	204	18	196	3.3e-16	56.5	COG0500	SAM-dependent methyltransferase	257
2852599752	73	24.87	8	72	31	77	3.2e-10	36.2	COG2169	Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), contains Zn-binding and two AraC-type DNA-binding domains	187
2852599753	238	96.61	3	238	9	236	1.0e-102	338.5	COG3826	Uncharacterized protein	236
2852599754	170	98.21	2	161	3	167	1.2e-46	155.6	COG0350	O6-methylguanine-DNA--protein-cysteine methyltransferase	168
2852599755	730	6.01	664	718	704	748	6.6e-95	36.5	COG3973	DNA helicase IV	747
2852599755	730	78.24	11	623	59	644	6.6e-95	277.2	COG3973	DNA helicase IV	747
2852599757	137	35.98	2	127	67	134	9.9e-09	31.7	COG2020	Protein-S-isoprenylcysteine O-methyltransferase Ste14	187
2852599759	145	89.05	5	136	4	125	1.0e-06	25	COG2764	Uncharacterized conserved protein PhnB, glyoxalase superfamily	136
2852599760	150	78.79	2	130	22	125	4.9e-27	90.6	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2852599762	499	83.75	222	493	12	248	9.3e-21	70	COG5607	CHAD domain (function unknown)	283
2852599763	664	93.99	4	320	1	297	8.4e-81	267.5	COG1984	Allophanate hydrolase subunit 2	314
2852599764	210	77.27	1	209	43	246	2.1e-57	190.6	COG3665	Uncharacterized conserved protein YcgI, DUF1989 family	264
2852599765	229	77.27	2	206	44	247	2.2e-20	61.9	COG3665	Uncharacterized conserved protein YcgI, DUF1989 family	264
2852599767	222	84.69	2	220	6	182	5.3e-24	82.2	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852599768	259	99.62	1	258	2	265	5.5e-68	225.5	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2852599769	278	97.76	17	278	2	263	4.2e-111	366.9	COG0413	Ketopantoate hydroxymethyltransferase	268
2852599771	502	88.14	55	435	2	261	1.9e-30	99.1	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852599772	149	70.37	7	144	39	152	4.0e-12	42.9	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2852599773	509	88.47	60	500	2	262	2.5e-26	88	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852599774	446	99.55	3	446	2	445	0.0e+00	533.4	COG0174	Glutamine synthetase	443
2852599775	988	99.38	33	974	6	962	0.0e+00	932.9	COG1391	Glutamine synthetase adenylyltransferase	963
2852599776	211	56.03	96	205	48	126	3.3e-08	28.8	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
2852599777	286	62.1	3	260	12	224	2.6e-46	154.2	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852599778	698	43.18	446	649	104	277	6.1e-30	44.7	COG3391	DNA-binding beta-propeller fold protein YncE	381
2852599778	698	43.92	304	474	26	202	6.1e-30	65.8	COG3391	DNA-binding beta-propeller fold protein YncE	381
2852599779	142	95.14	2	141	5	141	6.5e-25	84.5	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
2852599780	478	99.78	4	478	2	446	0.0e+00	576.1	COG0174	Glutamine synthetase	443
2852599783	310	95.1	3	305	13	303	2.9e-127	420.2	COG0320	Lipoate synthase	306
2852599784	223	93.78	2	222	4	214	5.8e-70	231.4	COG0321	Lipoate-protein ligase B	221
2852599785	303	98.65	6	300	1	293	3.0e-100	331.7	COG1090	NAD dependent epimerase/dehydratase family enzyme	297
2852599786	587	28.11	1	128	1	122	0.0e+00	131.4	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
2852599786	587	98.85	129	584	2	430	0.0e+00	467.3	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
2852599788	490	97.63	3	293	5	292	1.9e-30	103.1	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852599790	508	91.38	18	506	42	486	0.0e+00	509.2	COG0260	Leucyl aminopeptidase	485
2852599791	361	43.44	37	208	2	107	2.8e-50	44.5	COG2114	Adenylate cyclase, class 3	227
2852599791	361	70.9	203	361	59	231	2.8e-50	127.1	COG2114	Adenylate cyclase, class 3	227
2852599792	369	97.92	5	369	3	379	3.4e-117	387.8	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
2852599793	368	98.95	46	357	2	283	1.6e-92	306.7	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
2852599794	241	96.39	1	241	5	244	3.8e-51	170.7	COG0368	Cobalamin synthase	246
2852599795	345	94	2	345	9	337	8.2e-112	369.8	COG2038	NaMN:DMB phosphoribosyltransferase	347
2852599796	177	98.86	1	175	2	174	8.5e-50	165.2	COG2087	Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase	175
2852599798	351	39.42	1	157	2	150	3.3e-101	145.5	COG1929	Glycerate kinase	378
2852599798	351	51.59	153	351	179	373	3.3e-101	194.5	COG1929	Glycerate kinase	378
2852599799	118	94.55	10	118	6	109	5.6e-38	125.7	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
2852599801	324	98.42	2	311	2	312	1.2e-42	142.4	COG0524	Sugar or nucleoside kinase, ribokinase family	311
2852599802	643	99.64	1	635	2	547	0.0e+00	592	COG0367	Asparagine synthetase B (glutamine-hydrolyzing)	542
2852599803	344	98.43	10	329	4	253	2.1e-71	236.3	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
2852599805	286	22.65	73	285	34	122	2.2e-01	4.6	COG2948	Type IV secretory pathway, VirB10 components	360
2852599806	210	18.84	5	19	9	21	2.3e-02	7.1	COG1983	Phage shock protein PspC (stress-responsive transcriptional regulator)	70
2852599806	210	40.58	141	175	28	55	2.3e-02	2.6	COG1983	Phage shock protein PspC (stress-responsive transcriptional regulator)	70
2852599807	562	97.53	12	457	6	400	3.3e-92	305.2	COG1290	Cytochrome b subunit of the bc complex	381
2852599808	401	92.22	234	393	8	173	5.1e-27	90.2	COG0723	Rieske Fe-S protein	177
2852599809	268	54.27	135	235	54	142	1.2e-40	48.1	COG2010	Cytochrome c, mono- and diheme variants	150
2852599809	268	84.76	1	148	10	148	1.2e-40	86.7	COG2010	Cytochrome c, mono- and diheme variants	150
2852599810	203	89.2	2	203	21	210	1.2e-63	210.6	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
2852599811	352	99.12	6	351	3	339	1.2e-116	385.7	COG0547	Anthranilate phosphoribosyltransferase	338
2852599812	611	85.04	4	255	15	230	4.7e-49	163.4	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
2852599814	351	86.75	106	348	23	238	1.3e-40	136.7	COG0791	Cell wall-associated hydrolase, NlpC family	197
2852599816	375	97.8	1	375	3	402	2.3e-53	178.5	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2852599817	600	98.37	1	600	7	609	0.0e+00	626.4	COG1022	Long-chain acyl-CoA synthetase (AMP-forming)	613
2852599818	129	35.03	2	121	13	67	2.3e-03	14.1	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
2852599819	145	92.47	2	144	4	138	5.8e-08	28.7	COG2867	Ribosome association toxin PasT (RatA) of the RatAB toxin-antitoxin module	146
2852599820	399	94.28	1	323	19	331	4.8e-61	202.9	COG0003	Anion-transporting ATPase, ArsA/GET3 family	322
2852599822	241	80.08	1	224	32	240	9.3e-51	169	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
2852599823	425	54.65	68	413	151	444	1.1e-01	4.2	COG5650	Uncharacterized membrane protein	536
2852599824	295	22.64	14	257	57	190	1.6e-02	9.5	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2852599826	465	98.43	18	465	8	446	0.0e+00	723.7	COG3200	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase, class II	445
2852599827	564	98.47	5	397	4	390	1.9e-81	270.3	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2852599829	404	64.26	17	359	2	303	3.1e-62	207.3	COG0515	Serine/threonine protein kinase	384
2852599832	362	93.29	14	362	22	327	7.0e-70	229.8	COG0142	Geranylgeranyl pyrophosphate synthase	322
2852599834	203	95.77	15	203	4	184	3.4e-18	62.5	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2852599836	143	97.26	1	143	1	142	1.2e-49	164.2	COG2001	MraZ, DNA-binding transcriptional regulator and inhibitor of RsmH methyltransferase activity	146
2852599838	326	98.41	4	325	4	313	1.5e-112	372.5	COG0275	16S rRNA C1402 N4-methylase RsmH	314
2852599840	595	96.04	2	585	22	628	9.1e-129	426.9	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
2852599841	506	96.28	14	502	15	480	0.0e+00	520.4	COG0769	UDP-N-acetylmuramyl tripeptide synthase	475
2852599842	498	99.34	2	491	2	452	0.0e+00	531.8	COG0770	UDP-N-acetylmuramyl pentapeptide synthase	451
2852599843	359	97.24	1	355	8	324	1.3e-92	306.8	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
2852599844	466	98.89	1	463	5	449	0.0e+00	472	COG0771	UDP-N-acetylmuramoylalanine-D-glutamate ligase	448
2852599845	500	96.6	30	408	8	376	8.6e-115	379.6	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
2852599846	369	99.16	1	363	3	357	1.1e-101	336.9	COG0707	UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase	357
2852599847	486	98.7	4	471	5	459	0.0e+00	500.7	COG0773	UDP-N-acetylmuramate-alanine ligase	459
2852599848	302	92.99	50	302	6	257	5.4e-46	153.2	COG1589	Cell division septal protein FtsQ	269
2852599850	378	89.94	1	351	9	321	0.0e+00	471.3	COG0206	Cell division GTPase FtsZ	338
2852599851	228	92.83	1	228	18	250	3.4e-79	262.1	COG1496	Copper oxidase (laccase) domain	249
2852599852	249	99.13	10	246	2	228	1.5e-65	217.5	COG0325	Uncharacterized pyridoxal phosphate-containing protein, affects Ilv metabolism, UPF0001 family	228
2852599853	214	98.88	1	212	1	177	1.5e-49	163.7	COG1799	FtsZ-interacting cell division protein YlmF	167
2852599854	96	95.83	2	96	3	94	2.1e-18	62.9	COG0762	Uncharacterized conserved protein YggT, Ycf19 family	96
2852599855	272	100	1	225	1	220	7.8e-51	167.2	COG3599	Cell division septum initiation DivIVA, interacts with FtsZ, MinD and other proteins	212
2852599857	223	95	13	223	2	210	2.1e-90	298.3	COG1926	Predicted phosphoribosyltransferase	220
2852599858	446	98.99	151	445	1	294	1.6e-88	292.6	COG1090	NAD dependent epimerase/dehydratase family enzyme	297
2852599859	241	92.42	3	233	4	186	4.4e-29	98.1	COG0518	GMP synthase - Glutamine amidotransferase domain	198
2852599860	410	93.81	3	404	19	397	1.9e-47	158.6	COG1680	CubicO group peptidase, beta-lactamase class C family	390
2852599861	514	79.59	5	498	58	443	1.6e-30	98.7	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
2852599862	510	84.74	7	488	65	475	6.6e-33	108.8	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
2852599864	222	98.21	2	222	2	221	3.2e-69	229.1	COG4565	Response regulator of citrate/malate metabolism	224
2852599865	559	97.39	28	550	10	532	6.1e-105	347.7	COG3290	Sensor histidine kinase regulating citrate/malate metabolism	537
2852599866	325	97.49	3	325	7	317	2.8e-79	262.8	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2852599868	513	98.61	1	503	1	497	0.0e+00	629.5	COG3333	TctA family transporter	504
2852599869	130	94.97	2	129	8	158	2.4e-17	60.2	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2852599870	378	94.86	18	378	18	368	9.5e-100	330.1	COG0387	Ca2+/H+ antiporter	368
2852599871	1331	91.79	759	1331	50	597	0.0e+00	517	COG0369	Sulfite reductase, alpha subunit (flavoprotein)	587
2852599871	1331	94.44	1	719	45	809	0.0e+00	556.8	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2852599872	272	99.25	1	253	1	266	5.8e-60	199.4	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852599873	158	90	1	156	1	135	7.3e-34	113.3	COG1959	DNA-binding transcriptional regulator, IscR family	150
2852599874	249	84.78	1	248	1	234	1.4e-27	93.2	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
2852599876	444	96.41	2	444	11	413	1.2e-78	261.4	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2852599877	176	90.5	4	176	18	179	9.9e-53	174.7	COG1881	Uncharacterized conserved protein, phosphatidylethanolamine-binding protein (PEBP) family	174
2852599879	354	98.39	44	354	4	308	5.3e-105	347.1	COG0167	Dihydroorotate dehydrogenase	310
2852599881	327	16.41	84	162	120	184	1.1e-04	5.5	COG1520	Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat	370
2852599881	327	26.26	159	324	29	132	1.1e-04	11	COG1520	Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat	370
2852599883	282	98.9	4	277	3	272	5.9e-88	291.1	COG1968	Undecaprenyl pyrophosphate phosphatase UppP	270
2852599884	238	96.17	1	206	3	203	2.5e-46	154.2	COG0406	Broad specificity phosphatase PhoE	208
2852599887	257	91.3	2	256	11	262	3.6e-52	173.3	COG1218	3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase	276
2852599888	414	84.09	18	413	2	392	1.4e-116	386.5	COG0215	Cysteinyl-tRNA synthetase	464
2852599889	269	62.78	44	253	88	281	8.4e-26	86.8	COG0010	Arginase family enzyme	305
2852599890	292	86.19	2	239	3	233	4.5e-49	163.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852599891	478	94.32	16	478	27	474	3.2e-108	358.9	COG5361	Uncharacterized conserved protein	458
2852599894	296	56.33	62	261	90	227	6.2e-09	31.5	COG1938	Predicted ATP-dependent carboligase, ATP-grasp superfamily	244
2852599895	52	10.26	6	50	4	35	5.2e-03	12.6	COG0646	Methionine synthase I (cobalamin-dependent), methyltransferase domain	311
2852599896	1248	98.08	14	337	6	311	1.4e-121	401.4	COG0646	Methionine synthase I (cobalamin-dependent), methyltransferase domain	311
2852599896	1248	99.88	338	1212	2	857	0.0e+00	1270.3	COG1410	Methionine synthase I, cobalamin-binding domain	842
2852599897	267	98.19	1	257	1	271	3.4e-31	104.3	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
2852599898	226	96.83	1	222	2	215	4.5e-45	150.5	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
2852599899	487	34.2	297	469	46	176	2.8e-42	24.1	COG0477	MFS family permease	338
2852599899	487	75.46	23	316	6	294	2.8e-42	122.7	COG0477	MFS family permease	338
2852599900	87	86.46	4	87	2	84	3.7e-24	81.2	COG0140	Phosphoribosyl-ATP pyrophosphohydrolase	92
2852599901	288	99.32	5	288	2	292	3.1e-90	298.7	COG0040	ATP phosphoribosyltransferase	290
2852599902	163	97.39	5	158	2	150	2.8e-58	192.7	COG3918	Uncharacterized membrane protein	153
2852599903	456	99.56	1	449	2	454	0.0e+00	462.4	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
2852599904	215	91.55	10	195	6	200	6.4e-23	72.5	COG0655	Multimeric flavodoxin WrbA	207
2852599905	165	95.54	9	145	6	155	1.4e-15	53.5	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
2852599906	105	80.51	1	102	17	111	1.2e-18	64	COG0640	DNA-binding transcriptional regulator, ArsR family	110
2852599908	292	98.51	14	280	1	265	1.2e-72	241	COG2887	RecB family exonuclease	269
2852599909	279	98.44	6	263	2	254	1.5e-94	312.3	COG2519	tRNA A58 N-methylase Trm61	256
2852599910	98	93.68	1	94	2	90	2.5e-35	117	COG1550	Uncharacterized conserved protein YlxP, DUF503 family	95
2852599913	593	25.37	10	150	24	126	2.4e-73	19.6	COG1222	ATP-dependent 26S proteasome regulatory subunit	406
2852599913	593	43.42	532	587	36	68	1.0e-02	10.1	COG1837	Predicted RNA-binding protein YlqC, contains KH domain, UPF0109 family	76
2852599913	593	56.65	188	467	105	334	2.4e-73	220.5	COG1222	ATP-dependent 26S proteasome regulatory subunit	406
2852599915	384	70.5	27	373	26	295	1.9e-02	10.8	COG0477	MFS family permease	338
2852599916	380	80.42	29	360	13	320	2.9e-03	13.4	COG0477	MFS family permease	338
2852599917	412	94.8	2	241	14	250	1.3e-23	80	COG2966	Uncharacterized membrane protein YjjP, DUF1212 family	250
2852599921	269	83.47	17	241	28	224	1.3e-46	155	COG0638	20S proteasome, alpha and beta subunits	236
2852599922	245	94.92	2	238	6	229	1.1e-35	119.2	COG0638	20S proteasome, alpha and beta subunits	236
2852599923	238	95.42	2	230	10	238	1.3e-55	183.1	COG3361	Uncharacterized protein YqjF, DUF2071 family	240
2852599924	221	88.79	5	221	16	221	6.6e-46	152.9	COG1802	DNA-binding transcriptional regulator, GntR family	230
2852599925	410	98.97	23	400	3	386	6.2e-84	278.8	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2852599926	91	89.9	1	91	1	89	2.8e-37	123.3	COG4311	Sarcosine oxidase delta subunit	97
2852599927	946	98.96	549	946	3	383	2.9e-119	394.3	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
2852599927	946	99.53	21	431	1	428	5.6e-50	166.7	COG0446	NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase	415
2852599928	194	89.95	6	194	19	188	2.6e-39	131.4	COG4583	Sarcosine oxidase gamma subunit	189
2852599929	681	98.62	4	367	4	361	5.6e-97	321.2	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
2852599930	361	99.45	3	361	2	365	0.0e+00	437.8	COG1062	Zn-dependent alcohol dehydrogenase	366
2852599931	208	88.46	3	207	19	248	1.0e-39	132.9	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2852599932	820	97.68	1	396	4	382	6.7e-60	199.3	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2852599932	820	99.22	423	820	3	384	1.9e-100	332.2	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
2852599933	567	98.59	3	548	6	565	0.0e+00	482	COG2303	Choline dehydrogenase or related flavoprotein	542
2852599934	259	99.59	13	257	1	245	4.8e-74	244.7	COG1414	DNA-binding transcriptional regulator, IclR family	246
2852599935	383	96.28	18	383	4	365	6.4e-73	242.2	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
2852599936	389	85.58	4	367	2	369	6.3e-51	170.3	COG0446	NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase	415
2852599937	120	91.59	1	100	7	104	2.4e-24	81.6	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
2852599938	326	97.7	1	325	5	302	3.0e-40	134.5	COG2113	ABC-type proline/glycine betaine transport system, periplasmic component	302
2852599939	654	88.66	32	328	30	287	0.0e+00	281.9	COG4176	ABC-type proline/glycine betaine transport system, permease component	290
2852599939	654	92.1	372	654	13	280	0.0e+00	228.6	COG4176	ABC-type proline/glycine betaine transport system, permease component	290
2852599940	364	77.32	21	354	4	303	0.0e+00	443.9	COG4175	ABC-type proline/glycine betaine transport system, ATPase component	386
2852599941	492	99.16	5	485	3	477	0.0e+00	555.2	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2852599942	422	98.8	2	420	5	414	0.0e+00	602.2	COG0112	Glycine/serine hydroxymethyltransferase	413
2852599943	460	27.27	5	86	50	124	6.1e-117	11.1	COG1760	L-serine deaminase	262
2852599943	460	99.27	169	452	3	275	6.1e-117	375.1	COG1760	L-serine deaminase	262
2852599944	290	96.95	3	285	4	289	9.7e-40	133.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852599952	331	98.08	7	330	1	307	5.4e-67	222.6	COG2378	Predicted DNA-binding transcriptional regulator YafY, contains an HTH and WYL domains	311
2852599953	324	98.4	3	317	5	312	3.3e-74	246.4	COG2378	Predicted DNA-binding transcriptional regulator YafY, contains an HTH and WYL domains	311
2852599954	72	43.62	1	70	15	55	6.4e-14	48.7	COG1826	Sec-independent protein translocase protein TatA	94
2852599955	316	95.75	15	287	6	253	6.0e-75	248.2	COG0805	Sec-independent protein secretion pathway component TatC	255
2852599956	914	89.44	1	914	108	1039	0.0e+00	978.7	COG4581	Superfamily II RNA helicase	1041
2852599958	316	83.49	1	313	12	284	2.2e-52	174.8	COG0258	5'-3' exonuclease	310
2852599960	295	87.63	1	179	17	179	9.2e-30	99.7	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2852599961	154	66.13	10	148	61	183	9.0e-31	103.7	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
2852599963	131	98.63	6	126	2	145	3.6e-13	46.9	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2852599964	375	98.46	2	373	4	387	1.4e-98	326.9	COG0006	Xaa-Pro aminopeptidase	384
2852599966	249	93.21	2	249	8	254	6.1e-30	100.5	COG0300	Short-chain dehydrogenase	265
2852599967	401	98.1	1	205	1	206	1.4e-58	193.6	COG2241	Precorrin-6B methylase 1	210
2852599967	401	98.4	210	401	3	186	5.6e-58	191.5	COG2242	Precorrin-6B methylase 2	187
2852599968	266	97.65	14	266	2	250	5.9e-104	343.1	COG2875	Precorrin-4 methylase	254
2852599969	240	97.28	1	240	3	252	4.1e-76	252.1	COG2099	Precorrin-6x reductase	257
2852599971	492	12.8	2	43	2	33	4.8e-111	18.3	COG1010	Precorrin-3B methylase	249
2852599971	492	34.8	78	183	65	151	4.8e-111	30.3	COG1010	Precorrin-3B methylase	249
2852599971	492	97.6	246	492	2	245	4.8e-111	314.7	COG1010	Precorrin-3B methylase	249
2852599972	208	95.73	1	208	4	205	5.1e-72	238.2	COG2082	Precorrin isomerase	210
2852599973	291	93.69	4	291	10	291	6.3e-26	87.7	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2852599974	195	89.8	3	195	16	191	2.0e-26	89.4	COG5516	Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding	196
2852599975	371	79.96	1	364	29	439	9.5e-55	175.6	COG0155	Sulfite reductase, beta subunit (hemoprotein)	510
2852599978	306	98.95	1	282	1	284	4.9e-78	258.8	COG2175	Taurine dioxygenase, alpha-ketoglutarate-dependent	286
2852599980	1190	85.99	5	1190	53	1273	0.0e+00	1273.5	COG1429	Cobalamin biosynthesis protein CobN, Mg-chelatase	1388
2852599981	126	63.79	2	125	39	149	2.3e-14	50.1	COG3576	Predicted flavin-nucleotide-binding protein, pyridoxine 5'-phosphate oxidase superfamily	173
2852599982	127	44.25	1	98	23	99	7.3e-09	32	COG3576	Predicted flavin-nucleotide-binding protein, pyridoxine 5'-phosphate oxidase superfamily	173
2852599983	160	94.41	1	160	6	157	1.2e-25	86.4	COG3030	Protein affecting phage T7 exclusion by the F plasmid, UPF0716 family	158
2852599984	528	94.39	1	510	7	511	5.4e-130	430.6	COG1574	Predicted amidohydrolase YtcJ	535
2852599985	589	96.35	54	580	18	518	1.2e-126	419.7	COG0815	Apolipoprotein N-acyltransferase	518
2852599986	254	49.03	10	248	7	182	8.9e-20	68.4	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2852599989	403	96.95	133	403	7	292	1.0e-33	113.1	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852599991	271	96.9	17	271	5	254	1.5e-77	256.8	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2852599992	241	93.63	10	240	5	239	1.5e-75	250.1	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2852599993	338	93.73	1	333	9	322	3.7e-51	170.6	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2852599994	363	96.21	19	363	10	339	5.4e-77	255.4	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852599995	127	81.36	8	121	6	101	3.5e-20	68.8	COG0640	DNA-binding transcriptional regulator, ArsR family	110
2852599996	308	95.08	13	307	4	293	1.6e-82	273.4	COG0053	Divalent metal cation (Fe/Co/Zn/Cd) transporter	304
2852599998	502	98.99	4	500	4	492	0.0e+00	523.5	COG2272	Carboxylesterase type B	491
2852599999	644	95.26	1	637	29	651	0.0e+00	637.6	COG3733	Cu2+-containing amine oxidase	654
2852600001	268	81.34	1	264	7	224	6.6e-37	123.9	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852600002	109	97.25	3	109	2	107	1.8e-38	127.4	COG1742	Uncharacterized inner membrane protein YnfA, drug/metabolite transporter superfamily	109
2852600005	238	95.02	2	238	10	238	6.5e-48	159.5	COG2186	DNA-binding transcriptional regulator, FadR family	241
2852600006	172	96.89	8	166	1	156	1.1e-61	203.3	COG3265	Gluconate kinase	161
2852600007	489	99.33	22	489	3	448	3.9e-122	404.3	COG2610	H+/gluconate symporter or related permease	442
2852600008	156	78.41	11	156	16	153	8.4e-13	44.7	COG1714	Uncharacterized membrane protein YckC, RDD family	172
2852600009	284	86.81	2	148	18	142	3.9e-15	52.5	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
2852600010	168	15.35	40	163	123	196	1.4e-03	13.6	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
2852600011	465	93.63	2	462	6	475	1.7e-83	277.2	COG1070	Sugar (pentulose or hexulose) kinase	502
2852600013	439	97.57	1	439	7	448	1.1e-122	406.3	COG2270	MFS-type transporter involved in bile tolerance, Atg22 family	438
2852600016	310	66.33	53	278	2	263	1.7e-15	52.1	COG1409	3',5'-cyclic AMP phosphodiesterase CpdA	301
2852600017	153	69.53	48	153	39	127	9.7e-26	86.6	COG3794	Plastocyanin	128
2852600018	147	76.88	1	141	32	174	7.9e-23	77.4	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2852600020	188	97.65	3	188	3	168	3.5e-18	62.3	COG0262	Dihydrofolate reductase	167
2852600021	597	9.28	375	587	384	428	1.7e-10	3.3	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
2852600021	597	27.01	121	356	311	441	1.7e-10	31.6	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
2852600022	306	97.01	1	296	1	292	6.2e-43	143.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
2852600023	288	93.84	1	285	13	286	1.6e-68	227.2	COG5006	Threonine/homoserine efflux transporter RhtA	292
2852600025	222	98.71	2	221	2	230	8.6e-72	237.5	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2852600026	449	84.52	3	449	56	388	1.4e-63	209.4	COG0642	Signal transduction histidine kinase	336
2852600028	133	49.71	6	127	10	95	3.5e-03	13	COG1495	Disulfide bond formation protein DsbB	170
2852600029	280	95.51	17	279	7	261	2.5e-80	265.7	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
2852600030	291	93.4	4	289	10	278	2.8e-82	272.5	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
2852600031	393	96.3	16	391	6	369	1.2e-60	201.5	COG0687	Spermidine/putrescine-binding periplasmic protein	363
2852600032	357	93.48	1	341	22	351	4.9e-128	423.6	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2852600034	488	52.48	271	483	9	209	8.1e-30	27.8	COG0477	MFS family permease	338
2852600034	488	83.03	15	326	8	325	8.1e-30	75.1	COG0477	MFS family permease	338
2852600035	383	98.56	16	378	2	344	3.3e-93	308.7	COG3191	L-aminopeptidase/D-esterase	348
2852600036	220	55.2	13	216	43	196	8.8e-25	84.1	COG0500	SAM-dependent methyltransferase	257
2852600037	462	97.1	20	460	5	439	1.3e-66	221.2	COG1457	Purine-cytosine permease or related protein	442
2852600038	299	96.95	5	279	9	294	6.8e-49	163.3	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852600039	183	72.49	23	178	40	176	7.1e-18	61.4	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2852600040	297	88.71	1	167	14	178	9.9e-37	122.4	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2852600041	386	92.44	1	377	4	382	2.6e-68	226.8	COG1252	NADH dehydrogenase, FAD-containing subunit	405
2852600042	160	93.79	1	160	9	159	3.0e-27	91.7	COG3476	Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)	161
2852600043	325	94.19	1	323	8	315	9.7e-40	132.7	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
2852600044	357	96.51	1	353	10	368	6.8e-75	248.5	COG2843	Poly-gamma-glutamate biosynthesis protein CapA/YwtB (capsule formation), metallophosphatase superfamily	372
2852600045	248	78.9	13	243	15	201	2.0e-05	20.3	COG0412	Dienelactone hydrolase	236
2852600046	190	89	1	189	12	197	3.6e-22	76.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852600047	233	98.13	1	232	5	267	7.0e-70	231.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852600053	146	32	2	118	217	320	3.7e-26	88.1	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
2852600054	136	97.26	4	134	3	144	1.5e-11	41.4	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2852600055	808	13.39	15	162	3	128	0.0e+00	151.5	COG0178	Excinuclease UvrABC ATPase subunit	935
2852600055	808	71.63	155	793	266	939	0.0e+00	693.5	COG0178	Excinuclease UvrABC ATPase subunit	935
2852600057	587	97.09	49	538	6	438	2.7e-79	263.3	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
2852600058	498	97.09	15	458	9	441	8.1e-111	367.5	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
2852600059	219	95.33	2	219	3	206	1.6e-55	184.4	COG2258	Uncharacterized conserved protein YiiM, contains MOSC domain	210
2852600060	133	84.09	5	126	1	111	8.9e-24	80.5	COG0789	DNA-binding transcriptional regulator, MerR family	124
2852600061	153	46.99	9	124	37	114	1.1e-02	11.7	COG3467	Nitroimidazol reductase NimA or a related FMN-containing flavoprotein, pyridoxamine 5'-phosphate oxidase superfamily	166
2852600062	235	58.54	6	212	10	153	7.0e-16	54.7	COG2120	N-acetylglucosaminyl deacetylase, LmbE family	237
2852600063	385	95.84	14	377	11	402	1.6e-25	86.7	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2852600065	372	87.98	149	362	19	179	1.1e-41	138.6	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2852600068	230	71.57	1	228	4	227	3.5e-52	174.1	COG2378	Predicted DNA-binding transcriptional regulator YafY, contains an HTH and WYL domains	311
2852600070	130	92.37	2	129	10	130	1.3e-41	137.9	COG5485	Predicted ester cyclase	131
2852600071	339	97.81	1	313	1	313	1.2e-102	339.5	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2852600072	200	73.21	16	199	17	169	9.4e-15	52.2	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852600073	485	23.62	394	483	158	230	4.9e-10	9.8	COG3386	Sugar lactone lactonase YvrE	307
2852600073	485	66.34	228	448	31	235	4.9e-10	35.1	COG3386	Sugar lactone lactonase YvrE	307
2852600074	307	68.27	38	306	104	344	1.0e-05	19.1	COG4257	Streptogramin lyase	353
2852600080	109	89.83	2	103	9	114	1.4e-16	57.2	COG0640	DNA-binding transcriptional regulator, ArsR family	110
2852600081	149	94.9	1	144	5	153	1.2e-19	67.1	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
2852600082	118	87.4	1	114	13	123	4.7e-05	19.8	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
2852600085	316	89.67	17	303	24	240	2.9e-46	154.9	COG1376	Lipoprotein-anchoring transpeptidase ErfK/SrfK	232
2852600087	329	92.43	7	325	18	298	7.7e-44	146.5	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
2852600088	643	68.3	7	337	2	322	1.9e-62	207.9	COG0515	Serine/threonine protein kinase	384
2852600095	478	96.3	1	478	11	557	1.6e-88	290	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2852600097	160	67.74	8	154	56	181	4.6e-18	62.3	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
2852600098	209	97.69	2	206	5	215	1.3e-21	73.5	COG0778	Nitroreductase	207
2852600102	258	93.65	2	251	11	246	5.6e-64	211.9	COG2134	CDP-diacylglycerol pyrophosphatase	252
2852600104	468	86.53	1	443	10	465	1.6e-100	333.5	COG0442	Prolyl-tRNA synthetase	500
2852600105	523	49.55	26	209	57	165	1.0e-06	24	COG4122	Predicted O-methyltransferase YrrM	219
2852600105	523	83.27	263	505	6	229	1.2e-23	79.9	COG4797	Predicted regulatory domain of a methyltransferase	268
2852600106	311	65.33	179	307	32	129	5.9e-16	54.3	COG0526	Thiol-disulfide isomerase or thioredoxin	127
2852600108	232	86.04	1	222	35	262	1.6e-39	132	COG0300	Short-chain dehydrogenase	265
2852600109	209	46.18	17	208	127	241	1.4e-31	106.7	COG0791	Cell wall-associated hydrolase, NlpC family	197
2852600110	244	77.91	79	232	7	140	2.8e-03	12.3	COG2318	Uncharacterized damage-inducible protein DinB (forms a four-helix bundle)	172
2852600111	449	91.62	75	449	27	387	4.1e-48	161.5	COG0642	Signal transduction histidine kinase	336
2852600112	766	99.79	10	596	2	472	0.0e+00	657.4	COG2224	Isocitrate lyase	433
2852600113	143	40.91	9	136	133	231	1.1e-05	21.9	COG2202	PAS domain	232
2852600114	685	21.44	461	685	730	931	1.7e-104	154.7	COG2409	Uncharacterized membrane protein YdfJ, MMPL/SSD domain	937
2852600114	685	49.47	8	477	15	480	1.7e-104	197.1	COG2409	Uncharacterized membrane protein YdfJ, MMPL/SSD domain	937
2852600115	272	42.65	36	266	54	172	1.9e-18	63.6	COG0500	SAM-dependent methyltransferase	257
2852600120	251	76.26	21	250	29	179	7.5e-29	97.2	COG0518	GMP synthase - Glutamine amidotransferase domain	198
2852600122	318	98.37	3	313	4	304	4.2e-87	288.6	COG1131	ABC-type multidrug transport system, ATPase component	293
2852600123	246	68.94	44	246	86	287	1.7e-10	36.7	COG0842	ABC-type multidrug transport system, permease component	286
2852600124	254	68.6	17	251	87	287	8.6e-07	24.5	COG0842	ABC-type multidrug transport system, permease component	286
2852600127	1108	98.73	20	1026	3	932	0.0e+00	878.1	COG2409	Uncharacterized membrane protein YdfJ, MMPL/SSD domain	937
2852600128	188	81.82	5	187	15	185	8.7e-17	58.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852600129	304	93.46	1	290	2	301	2.7e-36	121.9	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2852600130	440	98.83	12	419	4	342	1.4e-99	329.7	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852600131	348	91.34	2	342	16	321	1.5e-50	168.5	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2852600132	239	94.82	8	238	4	241	1.2e-75	250.5	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2852600133	289	93.8	30	287	15	256	8.4e-76	251.1	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2852600134	151	94.48	2	147	7	143	1.0e-30	102.8	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
2852600135	748	96.61	10	748	25	737	0.0e+00	1206.9	COG0376	Catalase (peroxidase I)	730
2852600136	230	92.76	31	228	13	217	2.5e-06	20.2	COG2755	Lysophospholipase L1 or related esterase	216
2852600137	414	92.29	2	397	14	372	1.3e-69	231.1	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
2852600138	194	44.67	5	183	92	221	8.1e-03	11.9	COG1426	Cytoskeletal protein RodZ, contains Xre-like HTH and DUF4115 domains	284
2852600139	428	77.04	74	408	45	195	4.4e-40	133.9	COG0807	GTP cyclohydrolase II	193
2852600141	209	99.05	1	209	3	210	6.6e-86	283.7	COG0035	Uracil phosphoribosyltransferase	210
2852600143	219	54.85	56	215	93	222	3.2e-09	28.1	COG0412	Dienelactone hydrolase	236
2852600144	247	96.67	1	224	7	238	1.5e-71	230.5	COG4312	Predicted dithiol-disulfide oxidoreductase, DUF899 family	247
2852600145	239	18.75	143	216	185	229	2.0e-38	25.2	COG4312	Predicted dithiol-disulfide oxidoreductase, DUF899 family	247
2852600145	239	56.67	1	145	10	145	2.0e-38	102.4	COG4312	Predicted dithiol-disulfide oxidoreductase, DUF899 family	247
2852600146	258	76.27	1	109	16	105	1.7e-13	46.7	COG0640	DNA-binding transcriptional regulator, ArsR family	110
2852600147	3856	43.38	3201	3303	66	124	1.1e+00	9.4	COG3631	Ketosteroid isomerase-related protein	133
2852600147	3856	95.9	203	440	9	242	7.3e-37	123.6	COG2114	Adenylate cyclase, class 3	227
2852600150	248	87.75	1	246	2	223	9.3e-35	116.8	COG3022	Cytoplasmic iron level regulating protein YaaA, DUF328/UPF0246 family	253
2852600151	97	94.79	1	95	4	94	1.2e-20	69.9	COG5470	Uncharacterized conserved protein, DUF1330 family	96
2852600154	291	72	27	283	37	252	6.5e-44	146.7	COG3662	Uncharacterized conserved protein, DUF2236 family	300
2852600155	543	97.71	1	540	6	560	1.8e-117	389.4	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2852600158	475	98.54	6	474	7	480	2.8e-104	346	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
2852600160	304	98.31	11	301	4	293	6.9e-29	97.8	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852600161	323	92.65	1	296	4	318	1.1e-39	131.5	COG0331	Malonyl CoA-acyl carrier protein transacylase	310
2852600163	569	79.25	4	259	46	278	2.2e-37	124.4	COG0777	Acetyl-CoA carboxylase beta subunit	294
2852600165	280	95.86	7	272	6	283	1.9e-47	157.3	COG1767	Triphosphoribosyl-dephospho-CoA synthetase	288
2852600167	259	92.54	8	259	19	291	2.8e-11	39.9	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852600168	403	88.95	31	401	40	385	1.1e-77	257.6	COG4552	Predicted acetyltransferase	389
2852600169	124	82.39	1	124	6	122	2.2e-16	55.3	COG4747	Uncharacterized conserved protein, contains tandem ACT domains	142
2852600171	164	95.05	1	164	4	176	2.3e-50	167.3	COG2110	O-acetyl-ADP-ribose deacetylase (regulator of RNase III), contains Macro domain	179
2852600172	366	97.29	4	366	3	361	2.0e-63	211.1	COG2170	Gamma-glutamyl:cysteine ligase YbdK, ATP-grasp superfamily	369
2852600173	236	86.73	11	235	21	216	6.2e-41	136.4	COG4340	Uncharacterized protein	226
2852600175	424	95.33	2	264	3	247	5.5e-63	208.8	COG1058	Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA	255
2852600176	128	83.69	2	128	18	135	4.1e-28	94.2	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
2852600178	447	71.06	57	446	51	379	5.1e-60	199.4	COG0076	Glutamate or tyrosine decarboxylase or a related PLP-dependent protein	460
2852600179	248	98.51	2	244	4	267	2.3e-69	230.3	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852600180	357	98.86	1	356	1	346	6.9e-117	386.5	COG3804	Uncharacterized protein	350
2852600181	253	93.4	18	244	7	204	2.1e-49	164.1	COG0560	Phosphoserine phosphatase	212
2852600182	377	98.84	1	372	3	343	5.3e-82	271.6	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
2852600184	198	82.3	1	193	15	186	1.0e-09	35.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852600185	748	94.69	1	743	43	809	9.2e-112	370.2	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2852600186	133	93.84	5	131	7	143	9.5e-08	27.8	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2852600187	182	86.6	6	182	19	199	5.8e-13	46.3	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852600191	416	95.96	1	409	15	418	6.8e-93	308.1	COG2124	Cytochrome P450	411
2852600193	131	25.98	2	98	158	223	7.3e-03	12.1	COG4121	tRNA U34 5-methylaminomethyl-2-thiouridine-forming methyltransferase MnmC	252
2852600194	260	50.77	11	177	2	67	6.7e-12	42.4	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2852600196	189	84.67	1	134	9	124	3.8e-20	68.1	COG1695	DNA-binding transcriptional regulator, PadR family	138
2852600197	124	66.92	1	97	11	97	4.4e-03	13.2	COG4308	Limonene-1,2-epoxide hydrolase	130
2852600198	240	93.78	1	237	2	227	1.8e-50	167.9	COG2186	DNA-binding transcriptional regulator, FadR family	241
2852600199	224	62.63	20	206	69	244	5.8e-02	7	COG3000	Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily	271
2852600200	238	92.56	2	238	17	240	4.2e-44	147.7	COG1376	Lipoprotein-anchoring transpeptidase ErfK/SrfK	232
2852600202	488	99.2	1	488	4	498	0.0e+00	461.9	COG3104	Dipeptide/tripeptide permease	498
2852600204	315	92.2	1	315	7	325	1.6e-100	333	COG1171	Threonine dehydratase	347
2852600206	138	92.81	2	137	7	135	1.2e-30	102.5	COG0824	Acyl-CoA thioesterase FadM	137
2852600207	343	94.82	22	330	16	308	3.0e-84	279.1	COG0010	Arginase family enzyme	305
2852600209	327	77.97	2	325	10	278	3.3e-50	167.1	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
2852600210	125	84.67	1	123	11	126	5.6e-17	58.5	COG3011	Predicted thiol-disulfide oxidoreductase YuxK, DCC family	137
2852600211	169	96.45	5	169	2	164	6.1e-51	169	COG1247	L-amino acid N-acyltransferase YncA	169
2852600213	152	94.7	7	123	2	126	5.2e-28	94.2	COG0789	DNA-binding transcriptional regulator, MerR family	124
2852600214	239	90.3	7	235	6	247	8.4e-40	133.2	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852600215	354	94.56	6	351	17	346	2.2e-59	197.1	COG0809	S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase)	348
2852600216	210	92.82	10	210	9	202	4.5e-26	89.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852600217	279	96.61	1	278	5	289	2.3e-33	112.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852600218	294	97.2	2	293	9	286	7.8e-117	385.7	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
2852600219	307	85.19	153	294	23	160	1.1e-13	48.2	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2852600219	307	87.97	7	140	15	131	4.4e-21	71.2	COG1846	DNA-binding transcriptional regulator, MarR family	126
2852600220	324	87.96	4	321	37	321	9.3e-83	274.3	COG0627	S-formylglutathione hydrolase FrmB	316
2852600223	193	77.23	35	116	23	100	5.3e-15	48.1	COG1605	Chorismate mutase	101
2852600224	95	66.67	1	91	4	69	1.1e-11	41	COG1359	Quinol monooxygenase YgiN	100
2852600226	294	93.39	2	217	14	225	3.5e-33	111.6	COG0785	Cytochrome c biogenesis protein CcdA	220
2852600227	167	54	12	162	24	104	3.3e-11	40.1	COG0526	Thiol-disulfide isomerase or thioredoxin	127
2852600228	293	93.88	3	293	15	336	2.0e-41	136.9	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852600230	396	93.32	3	386	22	398	3.0e-67	224	COG1680	CubicO group peptidase, beta-lactamase class C family	390
2852600233	319	85.85	7	319	42	314	5.0e-63	209.9	COG0657	Acetyl esterase/lipase	312
2852600235	167	42.34	5	135	14	71	1.4e-03	14.5	COG4319	Ketosteroid isomerase homolog	137
2852600237	637	98.88	128	597	5	445	1.4e-89	296.2	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
2852600238	427	97.86	16	425	9	420	5.1e-109	361.2	COG2124	Cytochrome P450	411
2852600239	441	83.21	1	341	6	332	1.3e-27	93.3	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2852600240	214	85.17	5	214	9	186	5.5e-17	59.3	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852600241	226	96.4	6	218	6	219	2.2e-43	145	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
2852600242	149	17.15	1	120	440	533	5.4e-04	15.1	COG1766	Flagellar biosynthesis/type III secretory pathway M-ring protein FliF/YscJ	545
2852600244	137	85.16	15	137	19	127	1.0e-12	44.8	COG3794	Plastocyanin	128
2852600245	409	91.48	16	389	14	378	1.7e-47	158.5	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852600246	338	95.63	10	338	9	336	7.5e-64	212.2	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852600247	435	99.55	1	434	2	445	3.7e-103	341.9	COG0174	Glutamine synthetase	443
2852600248	476	93.9	14	472	6	467	2.7e-41	137.6	COG0531	Amino acid transporter	466
2852600249	250	89.63	2	250	29	270	1.2e-56	188	COG1464	ABC-type metal ion transport system, periplasmic component/surface antigen	268
2852600250	175	44.83	29	168	127	230	1.7e-26	89.3	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2852600252	223	93.81	3	223	8	219	1.0e-42	142.5	COG3619	Uncharacterized membrane protein YoaK, UPF0700 family	226
2852600253	368	96.33	1	367	3	396	7.6e-33	111	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2852600254	303	96.2	79	303	7	234	3.3e-41	137.8	COG0412	Dienelactone hydrolase	236
2852600255	307	96.27	8	300	3	260	1.9e-29	99.4	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852600256	594	99.14	1	589	5	578	0.0e+00	534.6	COG3653	N-acyl-D-aspartate/D-glutamate deacylase	579
2852600257	147	89.23	1	127	10	125	1.7e-06	24.2	COG4308	Limonene-1,2-epoxide hydrolase	130
2852600258	587	97.24	1	587	6	568	0.0e+00	456.6	COG3653	N-acyl-D-aspartate/D-glutamate deacylase	579
2852600259	370	95.39	1	370	12	301	1.2e-48	162.5	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
2852600260	453	96.86	9	448	5	436	2.1e-86	286.5	COG0174	Glutamine synthetase	443
2852600261	160	66.67	12	153	54	177	2.8e-12	43.4	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
2852600262	684	50.91	278	525	8	202	6.0e-42	10.5	COG0477	MFS family permease	338
2852600262	684	87.47	24	335	4	338	6.0e-42	134.4	COG0477	MFS family permease	338
2852600263	161	98.73	1	157	1	155	5.6e-66	217.6	COG2193	Bacterioferritin (cytochrome b1)	157
2852600265	63	85.71	1	61	1	54	1.2e-18	63.5	COG2906	Bacterioferritin-associated ferredoxin	63
2852600266	349	88.69	3	341	15	304	1.3e-37	125.9	COG3173	Predicted  kinase, aminoglycoside phosphotransferase (APT) family	321
2852600267	252	94.72	2	252	9	259	8.2e-61	201.9	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2852600273	663	97.67	16	663	7	676	1.3e-22	75.6	COG1289	Uncharacterized membrane protein YccC	674
2852600276	207	60.28	90	204	47	131	6.7e-09	31.6	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
2852600277	182	80.86	1	182	6	174	6.5e-15	52.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852600278	266	95.93	1	261	10	292	2.4e-35	118.9	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852600280	464	96.05	11	456	10	471	3.0e-91	303	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
2852600281	229	94.66	17	221	5	199	4.5e-44	146.8	COG1335	Nicotinamidase-related amidase	205
2852600282	531	31.4	105	177	17	54	7.5e-01	2.5	COG2456	Uncharacterized protein	121
2852600282	531	32.23	161	231	42	80	7.5e-01	6.2	COG2456	Uncharacterized protein	121
2852600283	206	92.82	1	201	8	201	1.0e-52	175.1	COG2860	Uncharacterized membrane protein YeiH	209
2852600285	196	76.08	2	192	7	165	1.1e-13	48.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852600287	557	76.9	5	542	49	331	6.4e-11	32.2	COG0457	Tetratricopeptide (TPR) repeat	291
2852600288	159	71.9	2	154	5	114	1.5e-23	79.9	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
2852600289	425	23.6	10	128	2	123	5.5e-46	66.2	COG0366	Glycosidase	505
2852600289	425	69.05	113	399	143	499	5.5e-46	93.3	COG0366	Glycosidase	505
2852600290	156	97.2	10	155	3	141	1.1e-61	203.2	COG5579	Uncharacterized protein, DUF1810 family	143
2852600291	728	92.21	494	728	7	231	6.9e-37	122.9	COG2114	Adenylate cyclase, class 3	227
2852600292	464	64.91	7	359	37	258	4.2e-36	121	COG0668	Small-conductance mechanosensitive channel	316
2852600293	418	97.23	35	409	2	352	2.7e-119	394.3	COG1304	FMN-dependent dehydrogenase, includes L-lactate dehydrogenase and type II isopentenyl diphosphate isomerase	360
2852600294	331	97.22	4	329	9	323	6.8e-91	301.2	COG0627	S-formylglutathione hydrolase FrmB	316
2852600295	243	97.15	1	243	6	244	8.3e-75	248	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
2852600297	779	98.34	1	777	7	777	0.0e+00	856.5	COG0466	ATP-dependent Lon protease, bacterial type	782
2852600298	341	91.84	14	329	18	332	6.0e-31	103.8	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852600299	110	50.41	1	106	1	61	1.0e-02	11.9	COG3070	Transcriptional regulator of competence genes, TfoX/Sxy family	121
2852600300	256	94.36	12	256	2	252	4.2e-60	200	COG1801	Uncharacterized conserved protein YecE, DUF72 family	263
2852600301	396	88.37	7	396	2	381	1.3e-80	268.2	COG0446	NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase	415
2852600303	264	91.04	3	255	4	247	6.7e-43	143.4	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852600304	491	90.1	2	463	12	366	1.3e-24	81.7	COG0183	Acetyl-CoA acetyltransferase	392
2852600305	763	25.94	645	755	297	400	0.0e+00	60.8	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2852600305	763	64.84	375	650	7	266	0.0e+00	224	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2852600305	763	93.52	1	384	7	381	0.0e+00	213.2	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2852600306	294	65.6	4	290	17	241	1.1e-52	175.4	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852600307	792	98.87	1	788	9	792	0.0e+00	1267.4	COG3957	Phosphoketolase	793
2852600308	249	92.61	15	249	16	228	4.2e-25	85.1	COG1266	Membrane protease YdiL, CAAX protease family	226
2852600309	194	89.29	8	194	18	192	4.6e-22	75.3	COG5516	Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding	196
2852600311	338	98.24	3	338	3	337	2.3e-98	325.6	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
2852600312	92	96.34	3	89	2	80	2.8e-18	61.9	COG2261	Uncharacterized membrane protein YeaQ/YmgE, transglycosylase-associated protein family	82
2852600315	352	94.57	4	350	19	349	1.5e-90	300.3	COG1118	ABC-type sulfate/molybdate transport systems, ATPase component	345
2852600316	259	93.33	38	257	3	212	1.8e-71	236.1	COG4149	ABC-type molybdate transport system, permease component	225
2852600317	241	96.64	19	237	8	266	1.2e-25	86.4	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852600318	308	89.21	12	295	14	319	8.5e-58	187.3	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852600319	456	99.27	9	424	2	408	0.0e+00	463.1	COG1252	NADH dehydrogenase, FAD-containing subunit	405
2852600321	225	96.46	15	222	7	197	2.6e-67	222.3	COG0378	Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase	202
2852600322	211	98.69	1	211	4	229	2.4e-45	151.7	COG0830	Urease accessory protein UreF	229
2852600323	573	100	1	573	1	569	0.0e+00	983	COG0804	Urease alpha subunit	568
2852600325	104	96.23	1	104	2	103	9.2e-43	141	COG0832	Urease beta subunit	106
2852600326	100	99	1	100	1	99	2.1e-50	165.4	COG0831	Urease gamma subunit	100
2852600327	134	82.98	2	134	18	134	1.1e-28	96.1	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
2852600328	125	92.11	16	125	7	111	8.2e-20	67.1	COG0607	Rhodanese-related sulfurtransferase	110
2852600330	138	97.6	1	126	3	124	2.2e-40	134.4	COG3682	Predicted transcriptional regulator	123
2852600331	316	93.91	2	312	11	303	2.8e-20	68.2	COG0501	Zn-dependent protease with chaperone function	302
2852600332	487	99.16	10	484	3	472	0.0e+00	709.1	COG0362	6-phosphogluconate dehydrogenase	473
2852600333	478	96.33	1	214	4	213	2.9e-73	98.3	COG0516	IMP dehydrogenase/GMP reductase	170
2852600333	478	97.71	254	476	2	214	2.9e-73	144.3	COG0516	IMP dehydrogenase/GMP reductase	170
2852600334	455	98.86	4	450	3	435	3.5e-126	417.8	COG1253	Hemolysin or related protein, contains CBS domains	429
2852600335	350	77.85	1	350	4	344	1.0e-94	314.1	COG1253	Hemolysin or related protein, contains CBS domains	429
2852600337	728	99.65	4	727	1	574	0.0e+00	774.8	COG2225	Malate synthase	545
2852600339	291	95.59	11	289	12	293	2.9e-29	98.9	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852600340	943	17.1	47	167	42	126	0.0e+00	1.5	COG1003	Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain	496
2852600340	943	28.17	227	413	225	364	0.0e+00	39.4	COG1003	Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain	496
2852600340	943	94.16	433	915	25	492	0.0e+00	705.8	COG1003	Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain	496
2852600342	206	93.18	50	180	6	128	9.8e-21	70.4	COG0789	DNA-binding transcriptional regulator, MerR family	124
2852600343	164	98.03	1	157	3	151	3.0e-53	176.2	COG1259	Bifunctional DNase/RNase	151
2852600344	243	73.48	12	225	1	97	6.9e-21	70.6	COG0789	DNA-binding transcriptional regulator, MerR family	124
2852600345	158	63.51	2	155	28	161	1.1e-33	113.2	COG1716	Forkhead associated (FHA) domain, binds pSer, pThr, pTyr	191
2852600346	131	96.18	1	131	4	129	1.3e-49	163.7	COG0509	Glycine cleavage system H protein (lipoate-binding)	131
2852600347	273	93.12	21	273	17	246	2.3e-60	200.3	COG3879	Uncharacterized conserved protein YlxW, UPF0749 family	247
2852600348	110	94.69	1	110	2	108	3.2e-49	162.2	COG3856	Small basic protein (function unknown)	113
2852600349	299	99.6	25	299	2	247	2.3e-64	213.5	COG3879	Uncharacterized conserved protein YlxW, UPF0749 family	247
2852600350	198	93.81	4	195	10	191	2.8e-37	124.9	COG0558	Phosphatidylglycerophosphate synthase	192
2852600351	777	14.88	634	768	692	816	0.0e+00	62.2	COG0653	Preprotein translocase subunit SecA (ATPase, RNA helicase)	822
2852600351	777	74.76	12	643	3	630	0.0e+00	734.2	COG0653	Preprotein translocase subunit SecA (ATPase, RNA helicase)	822
2852600352	279	35.82	79	275	173	268	2.7e-14	49.8	COG3393	Predicted acetyltransferase, GNAT family	268
2852600353	545	97.84	8	545	2	544	0.0e+00	462.9	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
2852600354	629	95.22	23	628	19	596	0.0e+00	583.4	COG4178	ABC-type uncharacterized transport system, permease and ATPase components	604
2852600355	642	97.69	22	639	4	596	0.0e+00	611.1	COG4178	ABC-type uncharacterized transport system, permease and ATPase components	604
2852600356	624	98.19	20	624	2	597	0.0e+00	600.8	COG4178	ABC-type uncharacterized transport system, permease and ATPase components	604
2852600357	482	72.44	14	482	4	413	1.5e-44	148.1	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
2852600358	159	41.78	89	157	2	62	4.6e-03	11	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2852600358	159	73.97	8	136	10	117	4.6e-03	12.7	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2852600359	215	88.54	22	153	10	148	1.3e-08	30.7	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
2852600360	112	78.81	3	97	19	111	1.0e-15	54.2	COG0640	DNA-binding transcriptional regulator, ArsR family	110
2852600363	228	66.99	1	226	10	149	7.7e-12	42.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852600366	467	98.2	41	430	5	385	6.2e-48	160.1	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2852600367	307	93.59	10	272	17	279	3.1e-47	157.8	COG3000	Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily	271
2852600368	512	98.99	1	510	2	490	0.0e+00	488.4	COG2272	Carboxylesterase type B	491
2852600369	83	14.62	22	80	104	147	2.8e-06	23.2	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2852600370	108	96.23	1	106	3	104	3.3e-27	91.4	COG2076	Multidrug transporter EmrE and related cation transporters	106
2852600371	390	48.56	192	390	24	209	1.3e-07	14.3	COG0477	MFS family permease	338
2852600371	390	81.98	4	256	6	319	1.3e-07	12.8	COG0477	MFS family permease	338
2852600372	302	75	1	269	3	203	8.4e-35	117	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852600373	205	73.68	3	201	11	164	3.6e-26	89.3	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852600374	430	98.23	24	406	7	394	1.9e-101	335.8	COG0019	Diaminopimelate decarboxylase	394
2852600375	715	97.92	162	708	6	523	0.0e+00	578.3	COG1640	4-alpha-glucanotransferase	520
2852600377	144	63.59	1	144	72	209	1.7e-09	33.8	COG5637	Uncharacterized membrane protein	217
2852600378	277	65.9	27	274	41	212	6.8e-20	66.6	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
2852600381	161	95.03	1	160	1	153	1.9e-69	228.7	COG4119	Predicted NTP pyrophosphohydrolase, NUDIX family	161
2852600382	339	97.65	1	335	8	339	6.1e-110	363.6	COG2130	NADPH-dependent curcumin reductase CurA	340
2852600383	345	96.92	5	321	4	318	1.4e-85	283.7	COG3491	Isopenicillin N synthase and related dioxygenases	322
2852600385	326	32.34	217	325	75	182	6.7e-80	41.8	COG4266	Allantoicase	334
2852600385	326	74.55	1	257	17	265	6.7e-80	229.3	COG4266	Allantoicase	334
2852600386	248	99.13	1	232	1	228	1.1e-57	191.4	COG4126	Asp/Glu/hydantoin racemase	230
2852600387	429	97.91	1	429	2	423	3.3e-114	378.4	COG0044	Dihydroorotase or related cyclic amidohydrolase	430
2852600388	268	73.85	8	267	26	217	3.6e-27	91.6	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2852600389	523	87.89	1	505	11	518	1.2e-60	202.4	COG0747	ABC-type transport system, periplasmic component	556
2852600390	209	96.12	9	198	6	203	9.5e-40	132.7	COG1335	Nicotinamidase-related amidase	205
2852600391	334	99.37	1	333	1	316	4.8e-89	295.2	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2852600392	288	89.26	10	288	27	292	7.2e-76	251.3	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2852600393	649	94.77	361	647	16	323	0.0e+00	245.8	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
2852600393	649	97.85	19	324	3	320	0.0e+00	360.5	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
2852600394	224	73.21	7	223	6	158	2.0e-21	73.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852600396	436	98.29	1	412	5	407	1.5e-96	320.2	COG1252	NADH dehydrogenase, FAD-containing subunit	405
2852600398	202	94.74	1	200	3	200	7.3e-27	91.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852600401	434	75.82	250	434	47	231	1.6e-34	114.8	COG2114	Adenylate cyclase, class 3	227
2852600405	256	92.76	2	202	11	215	5.1e-18	61.4	COG2755	Lysophospholipase L1 or related esterase	216
2852600407	187	34.4	48	102	28	70	1.7e-02	6.8	COG1844	Uncharacterized protein	125
2852600407	187	40.8	109	180	23	73	1.7e-02	3.8	COG1844	Uncharacterized protein	125
2852600411	327	97.53	1	323	7	322	9.2e-84	277.8	COG0627	S-formylglutathione hydrolase FrmB	316
2852600412	383	89.36	32	382	28	363	6.0e-50	161.7	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
2852600413	387	11.83	7	72	44	85	2.5e-11	13.2	COG5621	Predicted secreted hydrolase	354
2852600413	387	38.87	136	368	157	294	2.5e-11	24.3	COG5621	Predicted secreted hydrolase	354
2852600414	321	48.14	13	269	26	206	6.0e-36	120.7	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
2852600415	485	98.75	7	481	2	474	0.0e+00	522.2	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2852600416	275	98.49	1	272	5	265	1.5e-70	233.9	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2852600417	476	98.58	3	470	3	489	3.4e-106	351.9	COG2272	Carboxylesterase type B	491
2852600418	141	77.99	1	140	27	150	4.0e-10	35.5	COG2030	Acyl dehydratase	159
2852600419	176	86.79	3	172	13	150	1.7e-10	36.4	COG2030	Acyl dehydratase	159
2852600421	519	97.18	1	512	11	562	3.8e-82	272.7	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2852600422	370	92.52	28	139	4	102	1.0e-12	43.7	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
2852600423	413	97.62	1	413	10	420	1.6e-85	284	COG2124	Cytochrome P450	411
2852600425	762	26.43	646	755	296	401	0.0e+00	48.3	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2852600425	762	66.08	367	650	6	270	0.0e+00	229.4	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2852600425	762	92.27	11	368	8	377	0.0e+00	164.4	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2852600426	269	95.02	9	255	5	233	1.5e-42	141.9	COG2186	DNA-binding transcriptional regulator, FadR family	241
2852600427	242	89.18	2	220	6	244	1.4e-48	162	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852600429	385	83.88	14	373	48	302	3.3e-37	124.9	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
2852600430	347	76.32	9	343	70	301	2.8e-31	105.4	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
2852600431	119	96.26	1	119	2	104	9.3e-28	89.6	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
2852600432	407	93.59	4	405	27	420	1.5e-86	287.2	COG2124	Cytochrome P450	411
2852600433	385	100	1	382	1	366	3.4e-108	357.8	COG1062	Zn-dependent alcohol dehydrogenase	366
2852600434	354	80.92	5	354	56	301	7.8e-33	110.6	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
2852600435	532	96.13	2	515	12	557	1.2e-73	244.6	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2852600436	494	95.07	2	492	20	559	8.0e-90	294.7	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2852600437	287	96.6	4	270	4	259	3.3e-51	170.3	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2852600438	78	17.05	2	78	3	76	4.0e-12	42.6	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
2852600439	332	99.69	5	327	1	323	2.7e-120	397.4	COG0022	Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component	324
2852600440	326	87.99	2	324	30	344	4.2e-102	337.8	COG1071	TPP-dependent pyruvate or acetoin dehydrogenase subunit alpha	358
2852600442	288	98.13	2	279	4	266	2.6e-52	174.3	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852600443	380	99.25	1	380	2	397	6.0e-80	265.5	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852600444	354	98.25	1	354	3	394	1.5e-41	137.2	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852600445	406	98.75	1	405	6	401	4.4e-87	288.9	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2852600446	283	96.23	4	271	6	260	6.3e-48	159.6	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2852600447	572	22.08	1	161	4	128	4.6e-27	40	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
2852600447	572	51.06	193	571	134	422	4.6e-27	50.1	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
2852600448	449	67.29	38	153	4	75	4.7e-10	35	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
2852600450	218	68.9	1	212	3	146	2.0e-20	70.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852600452	968	98.73	6	946	6	935	0.0e+00	1085.8	COG2409	Uncharacterized membrane protein YdfJ, MMPL/SSD domain	937
2852600455	209	53.14	7	178	36	162	9.2e-28	92.2	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
2852600460	491	93.6	61	491	24	462	3.9e-37	123.9	COG0277	FAD/FMN-containing dehydrogenase	459
2852600464	332	83.33	17	327	45	314	1.0e-41	139.2	COG0627	S-formylglutathione hydrolase FrmB	316
2852600465	434	51.51	21	253	8	178	2.8e-02	12	COG3274	Surface polysaccharide O-acyltransferase, integral membrane enzyme	332
2852600469	211	75.6	9	210	11	168	4.5e-13	46.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852600470	299	7.49	233	267	318	343	3.9e-08	6.4	COG2951	Membrane-bound lytic murein transglycosylase B	343
2852600470	299	16.14	185	238	194	249	3.9e-08	28.3	COG2951	Membrane-bound lytic murein transglycosylase B	343
2852600470	299	21.61	3	187	75	149	3.9e-08	4.8	COG2951	Membrane-bound lytic murein transglycosylase B	343
2852600471	362	90.67	8	351	12	322	9.0e-58	192.2	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852600472	334	92.54	16	321	3	275	2.6e-36	122.1	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852600474	260	95.37	1	259	5	251	5.0e-44	146.8	COG0730	Uncharacterized membrane protein YfcA	258
2852600475	467	98.88	26	465	4	443	0.0e+00	538.3	COG1160	Predicted GTPases	444
2852600476	228	97.32	1	226	4	221	3.3e-80	265.2	COG0283	Cytidylate kinase	222
2852600477	247	97.97	5	247	3	243	6.7e-83	274	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
2852600478	238	93.48	26	209	4	175	6.2e-55	182	COG1386	Chromosome segregation and condensation protein ScpB	184
2852600479	272	97.58	11	266	2	243	3.1e-60	200.2	COG1354	Chromatin segregation and condensation protein Rec8/ScpA/Scc1, kleisin family	248
2852600480	286	97.73	31	286	2	259	3.0e-84	279.3	COG1192	Cellulose biosynthesis protein BcsQ	259
2852600481	251	79.09	27	250	15	188	1.2e-45	152	COG4122	Predicted O-methyltransferase YrrM	219
2852600482	103	40.77	3	94	18	70	4.9e-04	17.6	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2852600483	315	98.33	5	314	6	300	5.3e-112	370.2	COG4974	Site-specific recombinase XerD	300
2852600484	206	84.3	28	180	9	153	1.0e-18	63.8	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2852600485	591	99.63	16	559	1	533	0.0e+00	796	COG0504	CTP synthase (UTP-ammonia lyase)	533
2852600486	313	78.48	7	82	9	70	8.0e-03	13.1	COG4238	Outer membrane murein-binding lipoprotein Lpp	78
2852600487	394	99.75	1	394	1	394	0.0e+00	643.2	COG4825	Uncharacterized membrane-anchored protein	395
2852600488	127	95.89	5	123	6	145	4.6e-09	33.8	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2852600489	192	92.82	6	191	5	198	4.0e-18	63	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852600490	583	99.64	1	579	2	557	0.0e+00	597.9	COG0497	DNA repair ATPase RecN	557
2852600491	307	98.25	5	301	4	283	1.8e-76	253.2	COG0061	NAD kinase	281
2852600492	269	98.78	3	248	2	243	9.8e-96	316.1	COG1189	Predicted rRNA methylase YqxC, contains S4 and FtsJ domains	245
2852600494	340	97.04	1	265	4	265	1.0e-64	214.8	COG0647	Ribonucleotide monophosphatase NagD, HAD superfamily	269
2852600495	260	55.16	34	254	63	265	2.1e-05	21.2	COG0457	Tetratricopeptide (TPR) repeat	291
2852600498	769	76.25	697	769	17	77	9.5e-18	58.4	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2852600498	769	97.1	25	453	8	409	1.8e-70	234.2	COG3903	Predicted ATPase	414
2852600499	862	83.33	540	855	50	314	9.9e-79	260.7	COG0657	Acetyl esterase/lipase	312
2852600499	862	95.74	1	489	5	431	1.7e-95	317.1	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
2852600501	218	82.19	1	215	32	234	9.3e-16	54.1	COG4689	Acetoacetate decarboxylase	247
2852600502	215	84.21	4	207	8	183	2.2e-13	47.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852600503	475	96.21	9	474	11	441	6.0e-49	163	COG1457	Purine-cytosine permease or related protein	442
2852600504	250	82.31	4	244	19	232	3.6e-36	120	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2852600505	483	95.98	22	481	11	440	3.3e-44	147.3	COG1457	Purine-cytosine permease or related protein	442
2852600507	135	73.28	13	115	29	113	5.4e-17	57.7	COG3450	Predicted enzyme of the cupin superfamily	116
2852600508	321	79.7	2	320	64	385	5.0e-41	137.5	COG1680	CubicO group peptidase, beta-lactamase class C family	390
2852600509	238	76.05	1	233	72	306	7.9e-72	238.4	COG0010	Arginase family enzyme	305
2852600510	165	16.53	3	127	59	118	4.2e-03	12.5	COG3185	4-hydroxyphenylpyruvate dioxygenase and related hemolysins	363
2852600513	176	91.4	1	176	12	181	2.6e-13	46.5	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2852600518	1066	53.06	640	691	8	33	5.1e-04	4.6	COG1996	DNA-directed RNA polymerase, subunit RPC12/RpoP, contains C4-type Zn-finger	49
2852600518	1066	53.06	871	915	7	32	5.1e-04	9.4	COG1996	DNA-directed RNA polymerase, subunit RPC12/RpoP, contains C4-type Zn-finger	49
2852600518	1066	55.1	719	751	8	34	5.1e-04	7.6	COG1996	DNA-directed RNA polymerase, subunit RPC12/RpoP, contains C4-type Zn-finger	49
2852600518	1066	55.1	796	867	8	34	5.1e-04	2.8	COG1996	DNA-directed RNA polymerase, subunit RPC12/RpoP, contains C4-type Zn-finger	49
2852600518	1066	59.18	120	159	7	35	5.1e-04	11.3	COG1996	DNA-directed RNA polymerase, subunit RPC12/RpoP, contains C4-type Zn-finger	49
2852600518	1066	61.22	41	84	7	36	5.1e-04	4.8	COG1996	DNA-directed RNA polymerase, subunit RPC12/RpoP, contains C4-type Zn-finger	49
2852600518	1066	61.22	275	311	4	33	5.1e-04	3.2	COG1996	DNA-directed RNA polymerase, subunit RPC12/RpoP, contains C4-type Zn-finger	49
2852600521	132	22.37	8	120	68	118	3.0e-03	13.5	COG0765	ABC-type amino acid transport system, permease component	222
2852600522	505	64.26	7	445	2	303	1.4e-51	172.4	COG0515	Serine/threonine protein kinase	384
2852600523	180	68.56	2	180	42	174	3.0e-27	91.4	COG1525	Endonuclease YncB, thermonuclease family	192
2852600524	58	37.84	1	50	61	102	1.1e-02	12.4	COG4226	Predicted nuclease of the RNAse H fold, HicB family	111
2852600529	281	67.8	29	254	7	185	4.7e-15	52.1	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
2852600530	239	29.17	1	111	4	80	1.8e-21	39.2	COG1192	Cellulose biosynthesis protein BcsQ	259
2852600530	239	44.32	112	235	139	255	1.8e-21	32.5	COG1192	Cellulose biosynthesis protein BcsQ	259
2852600531	243	41.42	65	195	3	72	4.2e-03	13.4	COG5352	Uncharacterized protein	169
2852600532	516	97.77	4	495	5	487	2.2e-116	386.1	COG2272	Carboxylesterase type B	491
2852600533	180	88.42	1	169	18	185	3.3e-28	94.9	COG2320	GrpB domain, predicted nucleotidyltransferase, UPF0157 family	185
2852600534	264	98.11	2	257	2	260	1.3e-53	178.9	COG1192	Cellulose biosynthesis protein BcsQ	259
2852600539	107	95.88	1	100	1	93	7.4e-09	32	COG4842	Uncharacterized conserved protein YukE	97
2852600540	175	25.81	17	172	221	316	5.4e-04	15.5	COG3524	Capsule polysaccharide export protein KpsE/RkpR	372
2852600542	61	98.31	1	59	1	58	7.2e-29	95.8	COG3422	Uncharacterized conserved protein YegP, UPF0339 family	59
2852600543	549	94.36	291	548	3	253	4.0e-43	144	COG0455	MinD-like ATPase involved in chromosome partitioning or flagellar assembly	262
2852600549	457	98.54	3	417	3	406	1.9e-108	359.2	COG1252	NADH dehydrogenase, FAD-containing subunit	405
2852600550	192	30.73	25	187	10	143	7.3e-08	27.4	COG0305	Replicative DNA helicase	435
2852600552	78	88.75	2	75	2	72	2.8e-17	59.1	COG0695	Glutaredoxin	80
2852600553	512	67.8	28	291	32	210	7.8e-10	35.4	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
2852600555	496	80.59	57	446	33	385	5.7e-30	100.5	COG1541	Phenylacetate-coenzyme A ligase PaaK, adenylate-forming domain family	438
2852600558	876	86.25	791	869	9	77	2.5e-21	70.3	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2852600559	63	18.31	1	57	218	269	8.1e-07	25.2	COG2801	Transposase InsO and inactivated derivatives	232
2852600562	870	78.75	789	866	13	75	1.1e-20	68.2	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2852600563	189	88.36	7	189	21	187	3.4e-32	108.1	COG2020	Protein-S-isoprenylcysteine O-methyltransferase Ste14	187
2852600565	155	15.04	9	47	7	26	4.2e-10	3.9	COG3607	Predicted lactoylglutathione lyase	133
2852600565	155	42.11	67	135	75	130	4.2e-10	30.4	COG3607	Predicted lactoylglutathione lyase	133
2852600567	192	98.4	1	187	3	186	1.7e-62	206.9	COG4185	Predicted ABC-type ATPase	187
2852600573	145	70.94	25	130	15	97	5.0e-12	41.8	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
2852600575	238	40	12	167	3	54	2.3e-07	21	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2852600575	238	41.54	181	238	2	55	2.3e-07	6.3	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2852600578	346	49	64	342	126	247	2.5e-28	95.8	COG0791	Cell wall-associated hydrolase, NlpC family	197
2852600589	181	91.35	6	175	1	169	2.9e-26	88.6	COG0717	Deoxycytidine triphosphate deaminase	183
2852600590	202	60	44	197	39	149	7.9e-21	70.7	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
2852600591	192	93.33	1	191	7	188	3.3e-17	59	COG0194	Guanylate kinase	191
2852600594	336	93.51	11	189	3	175	2.1e-14	49.7	COG0717	Deoxycytidine triphosphate deaminase	183
2852600596	1391	95.82	81	1317	9	901	2.7e-97	321.5	COG1674	DNA segregation ATPase FtsK/SpoIIIE and related proteins	858
2852600599	258	66.08	55	257	88	274	3.2e-19	65.8	COG5486	Predicted metal-binding membrane protein	283
2852600600	452	11.34	342	436	386	440	2.9e-19	23	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
2852600600	452	19.18	220	352	54	146	2.9e-19	3.9	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
2852600600	452	30.72	52	257	295	443	2.9e-19	35.3	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
2852600601	479	58.91	56	477	120	453	2.2e-27	92.7	COG1404	Serine protease, subtilisin family	508
2852600604	336	19.96	16	139	56	155	1.3e-06	13.1	COG0753	Catalase	496
2852600604	336	22.75	180	321	245	358	1.3e-06	8.8	COG0753	Catalase	496
2852600606	358	86.73	1	358	2	354	1.2e-30	102.3	COG0644	Dehydrogenase (flavoprotein)	396
2852600611	926	22.93	218	373	15	61	3.5e-14	8.7	COG2078	Uncharacterized conserved protein, AMMECR1 domain	203
2852600611	926	61.95	418	581	45	171	3.5e-14	37.6	COG2078	Uncharacterized conserved protein, AMMECR1 domain	203
2852600611	926	76.85	14	215	28	183	4.3e-17	58.2	COG0461	Orotate phosphoribosyltransferase	201
2852600612	609	78.92	112	551	96	488	6.8e-23	77.5	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
2852600613	57	25.82	1	53	128	174	5.2e-06	22.8	COG2110	O-acetyl-ADP-ribose deacetylase (regulator of RNase III), contains Macro domain	179
2852600615	391	95.42	5	383	9	383	3.5e-57	190.8	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2852600617	120	28.33	23	120	21	105	5.7e-11	38.5	COG4974	Site-specific recombinase XerD	300
2852600619	740	21.47	136	266	47	157	1.6e-09	19.6	COG0366	Glycosidase	505
2852600619	740	24.95	272	706	143	271	1.6e-09	11.2	COG0366	Glycosidase	505
2852600621	340	96.25	4	334	3	310	4.0e-64	212.8	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2852600623	609	98.55	17	609	6	549	0.0e+00	566.9	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
2852600624	310	92.62	6	293	15	290	1.4e-62	207.5	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2852600625	335	98.11	20	335	5	316	2.0e-87	289.8	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2852600626	535	97.92	19	534	10	575	3.3e-80	266.8	COG0747	ABC-type transport system, periplasmic component	556
2852600627	594	97.48	3	567	2	542	0.0e+00	524.4	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
2852600629	521	96.13	19	516	8	553	7.3e-64	205.1	COG2303	Choline dehydrogenase or related flavoprotein	542
2852600630	671	98.62	8	370	4	361	1.4e-107	356.2	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
2852600631	338	88.7	1	271	25	283	3.5e-64	212.8	COG5006	Threonine/homoserine efflux transporter RhtA	292
2852600632	445	94.64	2	425	22	427	0.0e+00	472.1	COG0141	Histidinol dehydrogenase	425
2852600633	183	83.56	13	173	3	124	5.7e-13	46.3	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2852600634	454	92.36	1	441	31	465	0.0e+00	654.6	COG1027	Aspartate ammonia-lyase	471
2852600635	220	89.12	1	220	4	216	1.7e-54	181.5	COG3828	Type 1 glutamine amidotransferase (GATase1)-like domain	239
2852600637	543	96.34	21	497	8	481	5.7e-53	176.3	COG0531	Amino acid transporter	466
2852600638	353	99.7	2	351	1	333	1.1e-76	254.5	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2852600639	277	99.25	2	274	2	267	1.7e-59	197.9	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852600640	87	24.34	1	87	118	200	1.4e-21	73.3	COG3938	Proline racemase	341
2852600642	309	91.55	4	300	18	331	6.0e-38	127	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852600644	407	71.99	22	406	34	416	1.6e-14	50	COG5651	PPE-repeat protein	490
2852600645	111	92.78	6	110	4	93	3.8e-07	26.5	COG4842	Uncharacterized conserved protein YukE	97
2852600646	100	93.81	2	99	5	95	1.4e-07	28	COG4842	Uncharacterized conserved protein YukE	97
2852600649	455	93.98	200	455	3	252	5.7e-42	140.3	COG0455	MinD-like ATPase involved in chromosome partitioning or flagellar assembly	262
2852600651	545	81.83	1	537	22	485	1.6e-39	132.5	COG1404	Serine protease, subtilisin family	508
2852600654	726	67.45	7	409	2	318	2.5e-51	171.3	COG0515	Serine/threonine protein kinase	384
2852600658	235	97.69	15	235	5	215	9.6e-14	47.6	COG0778	Nitroreductase	207
2852600659	278	77.99	3	276	68	315	2.4e-55	184.7	COG0657	Acetyl esterase/lipase	312
2852600660	433	18.66	194	293	153	216	2.4e-49	35	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852600660	433	41.11	29	198	19	159	2.4e-49	131.1	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852600661	484	98.75	4	475	2	474	0.0e+00	539.1	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2852600662	341	80.87	7	339	2	335	2.7e-49	164.6	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
2852600663	301	98.06	2	301	4	307	3.7e-127	420.1	COG4569	Acetaldehyde dehydrogenase (acetylating)	310
2852600664	200	89.47	1	197	9	195	1.7e-22	77.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852600665	399	74.05	12	373	10	263	2.1e-40	134.6	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852600666	248	97.15	10	248	2	240	2.1e-65	216.4	COG1414	DNA-binding transcriptional regulator, IclR family	246
2852600667	277	98.88	3	275	3	267	6.9e-62	205.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852600668	194	84.86	20	189	9	165	3.4e-29	97.9	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
2852600673	176	75.12	1	174	27	183	3.3e-19	66.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852600674	406	96.49	20	405	12	396	1.5e-91	303.7	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852600675	350	90.67	9	347	19	329	1.4e-44	148.7	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852600676	520	96.83	3	517	8	557	2.7e-101	335.8	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2852600677	67	94.2	1	67	1	65	2.3e-16	55.7	COG1942	Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family	69
2852600678	256	98.11	1	255	1	259	1.2e-69	230.7	COG3971	2-keto-4-pentenoate hydratase	264
2852600679	261	96.97	1	261	6	261	1.0e-74	247.5	COG3971	2-keto-4-pentenoate hydratase	264
2852600680	326	24.08	3	96	5	89	1.5e-37	32.5	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
2852600680	326	61.47	90	319	123	339	1.5e-37	94.9	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
2852600681	340	69.18	152	278	2	102	9.2e-13	13.7	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2852600681	340	97.95	10	123	3	145	9.2e-13	32.4	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2852600682	757	23.94	629	742	295	390	7.8e-129	40	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2852600682	757	62.59	379	629	6	256	7.8e-129	172	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2852600682	757	93.77	1	383	16	391	7.8e-129	215.8	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2852600684	268	92.51	12	268	19	265	2.0e-80	266.1	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
2852600685	285	94.38	8	279	14	265	1.5e-70	233.6	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
2852600686	446	96.22	7	349	15	370	4.9e-67	222.8	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852600687	318	86.49	1	318	28	347	2.5e-71	237.1	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852600688	450	93.24	2	353	10	354	8.0e-71	235.1	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852600689	451	94.86	2	367	13	363	7.7e-78	258.2	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852600690	380	92.43	7	374	8	349	7.8e-71	235.3	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852600691	486	98.92	2	372	3	368	2.4e-76	253.4	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852600694	152	53.02	3	151	88	201	8.0e-06	22.2	COG2340	Uncharacterized conserved protein YkwD, contains CAP (CSP/antigen 5/PR1) domain	207
2852600696	296	92.59	2	296	19	318	3.0e-65	216.9	COG0627	S-formylglutathione hydrolase FrmB	316
2852600698	386	97.74	5	386	4	393	0.0e+00	442.9	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852600699	284	79.1	7	255	2	213	1.1e-38	129.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852600704	929	19.6	364	450	151	199	9.3e-03	7.7	COG3063	Tfp pilus assembly protein PilF	250
2852600704	929	22.8	583	674	48	104	9.3e-03	3.6	COG3063	Tfp pilus assembly protein PilF	250
2852600704	929	66.25	850	912	18	70	3.8e-15	50.1	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2852600708	533	92.21	5	533	40	572	7.4e-58	193	COG0747	ABC-type transport system, periplasmic component	556
2852600713	146	98.58	1	140	1	139	9.7e-23	77.8	COG1848	Predicted nucleic acid-binding protein, contains PIN domain	140
2852600716	932	14.26	482	598	259	329	2.7e-72	54.3	COG2319	WD40 repeat	466
2852600716	932	33.73	256	459	197	364	2.7e-72	74.6	COG2319	WD40 repeat	466
2852600716	932	60.84	596	910	160	462	2.7e-72	105	COG2319	WD40 repeat	466
2852600717	546	39.41	198	361	241	400	6.4e-38	65.7	COG4252	Extracellular (periplasmic) sensor domain CHASE2 (specificity unknown)	400
2852600717	546	41.87	2	197	5	174	6.4e-38	67.3	COG4252	Extracellular (periplasmic) sensor domain CHASE2 (specificity unknown)	400
2852600731	864	45.28	290	402	36	107	4.4e-03	12.6	COG1617	tRNA threonylcarbamoyladenosine modification (KEOPS) complex,  Cgi121 subunit	158
2852600733	589	49.18	237	517	117	297	2.5e-05	19.4	COG1223	Predicted ATPase, AAA+ superfamily	368
2852600734	216	92.54	2	215	17	227	2.6e-44	148	COG4291	Uncharacterized membrane protein	228
2852600736	105	17.66	9	100	2	84	5.4e-17	58.7	COG0515	Serine/threonine protein kinase	384
2852600745	428	92.48	59	315	3	248	8.2e-43	143	COG0455	MinD-like ATPase involved in chromosome partitioning or flagellar assembly	262
2852600748	53	22.27	1	52	157	203	2.0e-13	46.8	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2852600750	654	51.56	353	601	44	208	6.9e-14	47.3	COG4607	ABC-type enterochelin transport system, periplasmic component	320
2852600750	654	67.66	10	347	2	319	2.4e-59	197.5	COG0515	Serine/threonine protein kinase	384
2852600764	353	34.62	296	350	3	47	1.5e-09	13.5	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2852600764	353	53.85	126	266	3	72	1.5e-09	19.9	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2852600780	395	97.55	3	336	3	320	1.5e-29	99.5	COG3547	Transposase	303
2852600783	67	18.77	13	66	116	164	3.6e-03	12.6	COG2086	Electron transfer flavoprotein, alpha and beta subunits	260
2852600794	539	96.81	3	538	17	563	2.7e-103	342.8	COG2936	Predicted acyl esterase	563
2852600795	281	98.13	2	274	4	266	2.6e-66	220.3	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852600796	316	14.02	173	293	252	296	2.7e-21	8	COG3458	Cephalosporin-C deacetylase or related acetyl esterase	321
2852600796	316	49.53	2	168	58	216	2.7e-21	56.1	COG3458	Cephalosporin-C deacetylase or related acetyl esterase	321
2852600797	529	97.46	5	527	6	543	1.2e-115	383.1	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2852600798	482	98.65	3	373	5	369	3.2e-77	256.2	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852600799	379	94.32	4	369	5	353	5.0e-70	232.7	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852600800	444	95.41	3	369	11	363	1.4e-77	257.5	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852600801	436	93.24	1	355	9	353	6.4e-74	245.3	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852600802	342	90	3	342	15	347	1.5e-77	257.5	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852600803	451	99.46	6	348	3	370	1.4e-73	244.3	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852600804	269	89.51	3	263	27	265	1.6e-71	236.9	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
2852600805	283	93.63	19	283	16	265	7.7e-79	260.9	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
2852600806	257	98.87	1	254	4	265	3.1e-72	239.4	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2852600807	339	96.25	10	330	5	312	5.0e-92	304.3	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2852600808	519	96.87	5	507	3	466	4.7e-68	226	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2852600809	172	93.79	1	172	9	174	2.1e-48	160.5	COG0663	Carbonic anhydrase or acetyltransferase, isoleucine patch superfamily	176
2852600810	279	85.11	1	279	4	283	7.0e-90	297.9	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
2852600811	280	70.07	46	278	87	299	2.2e-37	125.3	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
2852600812	113	91.78	1	65	6	72	1.2e-13	47.1	COG1146	NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit	68
2852600813	342	98.7	10	326	4	306	5.0e-74	245.3	COG0492	Thioredoxin reductase	305
2852600815	576	32.08	321	545	130	214	1.6e-36	12.7	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2852600815	576	76.98	42	340	25	228	1.6e-36	107.9	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2852600818	683	97.88	29	636	7	559	1.5e-95	316.5	COG0146	N-methylhydantoinase B/oxoprolinase/acetone carboxylase, alpha subunit	563
2852600819	725	99.12	2	707	5	677	0.0e+00	498	COG0145	N-methylhydantoinase A/oxoprolinase/acetone carboxylase, beta subunit	674
2852600820	124	49.7	3	112	71	152	8.1e-11	38.3	COG4647	Acetone carboxylase, gamma subunit	165
2852600821	634	77.76	1	632	2	529	1.7e-78	256.5	COG0145	N-methylhydantoinase A/oxoprolinase/acetone carboxylase, beta subunit	674
2852600822	316	78.03	190	316	23	125	4.2e-14	48.4	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2852600823	388	97.72	1	387	8	392	2.4e-53	178	COG0183	Acetyl-CoA acetyltransferase	392
2852600824	601	39.15	313	583	354	593	3.3e-62	102.9	COG1022	Long-chain acyl-CoA synthetase (AMP-forming)	613
2852600824	601	42.9	35	307	28	290	3.3e-62	101.8	COG1022	Long-chain acyl-CoA synthetase (AMP-forming)	613
2852600825	301	90.17	6	288	14	279	4.6e-13	45.8	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2852600826	291	87.63	25	290	6	260	2.6e-59	197.3	COG3327	DNA-binding transcriptional regulator PaaX (phenylacetic acid degradation)	291
2852600827	258	98.11	3	252	3	262	6.9e-63	208.7	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2852600828	302	98.13	1	255	1	263	1.7e-62	207.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852600829	153	89.94	1	151	15	157	2.4e-39	130.5	COG2030	Acyl dehydratase	159
2852600830	316	80.45	1	316	73	393	3.5e-105	348.7	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852600831	402	99.75	1	402	1	393	3.9e-126	417.6	COG0183	Acetyl-CoA acetyltransferase	392
2852600832	316	85.25	1	315	55	366	5.5e-86	285.4	COG1062	Zn-dependent alcohol dehydrogenase	366
2852600834	786	77.5	702	775	13	74	3.1e-16	53.8	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2852600834	786	97.1	27	453	6	407	1.6e-91	303.4	COG3903	Predicted ATPase	414
2852600835	314	97.76	1	253	6	267	2.0e-57	190.9	COG1018	Ferredoxin-NADP reductase	266
2852600836	338	98.18	10	331	3	326	2.6e-70	233.5	COG2423	Ornithine cyclodeaminase/archaeal alanine dehydrogenase, mu-crystallin family	330
2852600837	339	65.89	59	307	53	249	1.3e-18	62.8	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
2852600838	480	98.96	8	480	2	475	0.0e+00	571.7	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2852600839	331	99	9	306	1	298	1.6e-31	106.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2852600840	265	98.51	1	263	4	267	1.3e-68	227.8	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852600842	193	95.12	25	193	2	157	6.2e-15	51.9	COG5517	3-phenylpropionate/cinnamic acid dioxygenase, small subunit	164
2852600843	436	84.57	5	435	7	324	1.2e-57	190.5	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
2852600845	86	13.64	1	78	235	276	3.5e-04	16.5	COG1073	Fermentation-respiration switch protein FrsA, has esterase activity, DUF1100 family	299
2852600847	312	97.26	7	122	3	144	7.1e-15	18.6	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2852600847	312	98.63	140	258	2	145	7.1e-15	32.5	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2852600848	330	57.99	160	330	90	216	1.1e-06	24.1	COG1878	Kynurenine formamidase	218
2852600849	299	84.98	5	288	40	271	2.2e-50	168	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
2852600850	224	87.56	5	222	3	185	1.1e-06	25.5	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852600851	247	86.42	1	246	6	234	2.9e-46	154	COG0300	Short-chain dehydrogenase	265
2852600852	470	49.87	23	275	4	194	9.5e-18	38.8	COG0477	MFS family permease	338
2852600852	470	50.39	279	470	3	195	9.5e-18	28	COG0477	MFS family permease	338
2852600853	825	91.85	46	498	1	383	1.8e-84	280.5	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
2852600854	725	85.85	13	420	47	404	2.8e-67	223	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
2852600855	352	84.35	20	352	30	320	1.1e-55	185.1	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
2852600856	258	89.07	13	253	9	228	2.0e-22	75.9	COG4689	Acetoacetate decarboxylase	247
2852600862	275	96.64	3	260	9	267	2.0e-29	99.1	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2852600863	301	84.53	3	270	8	231	1.1e-51	171.9	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2852600864	257	92.13	2	256	21	266	1.6e-76	253.4	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
2852600865	287	95.13	6	281	12	265	4.5e-70	232.1	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
2852600866	385	94.86	1	326	16	366	9.0e-58	192.2	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852600867	342	86.76	1	341	11	331	7.3e-66	219.1	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852600868	370	93.78	3	358	5	351	1.2e-57	191.9	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852600869	480	94.32	1	364	14	362	3.8e-70	233	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852600870	417	81.62	1	347	32	333	7.7e-63	209	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852600871	537	99.73	1	365	1	369	1.1e-71	238.2	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2852600873	219	64.15	1	215	95	298	1.8e-51	172	COG0657	Acetyl esterase/lipase	312
2852600875	331	90.5	2	331	21	344	6.4e-105	347	COG1071	TPP-dependent pyruvate or acetoin dehydrogenase subunit alpha	358
2852600876	333	97.84	10	333	6	322	2.2e-121	401	COG0022	Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component	324
2852600877	76	17.74	1	76	1	77	1.6e-21	73.4	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
2852600878	511	95.25	1	509	18	558	1.3e-85	284.1	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2852600879	104	76.7	1	103	18	96	2.3e-15	52.3	COG0633	Ferredoxin	102
2852600881	481	73.83	72	190	4	82	3.0e-06	23	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
2852600882	736	16.79	625	736	331	397	2.8e-111	20.8	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852600882	736	61.9	360	609	11	257	2.8e-111	201.1	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852600882	736	92.98	1	359	5	375	2.8e-111	151.8	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2852600883	209	77.03	2	199	12	172	9.0e-25	84.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852600884	420	68.42	117	420	93	300	6.7e-11	37	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
2852600886	473	8.56	303	392	129	156	7.3e-34	4.5	COG3173	Predicted  kinase, aminoglycoside phosphotransferase (APT) family	321
2852600886	473	84.1	1	302	9	283	7.3e-34	112.4	COG3173	Predicted  kinase, aminoglycoside phosphotransferase (APT) family	321
2852600888	266	60.64	2	241	19	226	1.8e-57	191.2	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2852600889	237	68.42	6	220	11	153	2.6e-21	73.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2852600891	95	26.35	1	95	261	353	1.7e-09	33.3	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
2852600892	470	99.25	212	467	3	265	2.4e-67	223.1	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
