Polymorphisms in the MTHFR gene have been studied as possible risk factors for a variety of common conditions.
MTHFR gene mutation is a highly significant public health problem that is not commonly looked into. The MTHFR mutation influences the health outcomes of people with Type 2 diabetes, cardiovascular disease, autism, fibromyalgia, miscarriages, schizophrenia, severe depression, and cancer to name a few.
The function of the MTHFR gene is simply to produce the MTHFR enzyme. However, if the MTHFR gene is mutated, the enzyme produced is not entirely correct. As a result, things don’t function properly.
The MTHFR gene is responsible for making a functional MTHFR enzyme. If the MTHFR gene is slightly altered (mutated), the MTHFR enzyme’s shape becomes distorted. Enzyme function depends a lot on shape. It is similar to the grooves on a key. If the grooves on a key are slightly different than the lock, the key may fit and turn the lock a little but it does not unlock the door.
The genetic code of the MTHFR enzyme must be perfect in order for it to function properly. A dysfunctional MTHFR enzyme may lead to a slew of health problems.
Here at Darwin Dietitians we are able to help interpret and provided necessary nutritional and lifestyle advice based on your methylation status.
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