Adjusted analysis1: when groups differ on baseline characteristics (eg, age), analyses of outcome data are statistically modified to account for these differences.
Blinding (masking): in an experimental study, refers to whether patients, clinicians providing an intervention, and people assessing outcomes were aware or unaware of the group to which patients were assigned. In the design section of Evidence-Based Nursing abstracts of treatment studies, the study will be identified as blinded, with specification of who was blinded; unblinded, if all parties were aware of patients' group assignments; or blinded (unclear) if the authors did not report or provide us with an indication of who was aware or unaware of patients' group assignments.
Case control1: an observational study that begins with patients who have the health problem (cases), and control participants who do not have the health problem and then looks backward to identify possible causal factors (eg, comparing patients with and without lung cancer for past exposure to tobacco).
Cluster randomisation2: randomisation of groups of people rather than individuals; this approach is often used to avoid “contamination” when the way in which people in one group are treated or assessed is likely to modify the treatment or …