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Findings from a retrospective cohort study conducted at a single hospital suggest that patients with sickle cell disease have a lower — and not higher — risk for Clostridioides difficile infection compared with the hospitalwide patient population, researchers reported in The New England Journal of Medicine.
In introducing their study, Seah H. Lim, MD, PhD, and colleagues from New York Medical College said health care-associated C. difficile infections “might be expected to be more common” in patients with sickle cell disease, and not less common, as the study found.
“Patients with sickle cell disease have defects in immune function; they are frequently hospitalized for painful vaso-occlusive crisis and are often given empirical antibiotic treatment for fever in this setting. They also have intestinal dysbiosis,” they wrote.
people & placesChildren’s Healthcare of Atlanta Sickle Cell Disease ProgramChildren's Healthcare of Atlanta's Sickl...
people & placesTexas Children’s HospitalThe Sickle Cell Center at Texas Children...
Community CenterCalifornia Sickle Cell ResourcesThe Comprehensive Sickle Cell Center at ...
education & researchPneumococcal vaccination coverage among children with sickle cell anemia, sickle cell trait, and normal hemoglobinBackground: Children with sickle cell a...
news & eventsHospitals See No Link Between US Opioid Crisis and Patients’ Use of Treatment, Study ReportsThe U.S. opioid epidemic is not linked t...
education & researchImmunoglobulin G Responses Against Falciparum Malaria Specific Antigens are Higher in Children with Homozygous Sickl...Background: High Immunoglobulin G (IgG)...
news & eventsRandomized Trials Needed to Assess Benefits of Salmonella Vaccines in SCD Patients, Study SaysRandomized controlled trials are needed ...
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This platform is made possible through a partnership with the Sickle Cell Disease Association of America, Inc. (SCDAA) and its member organizations. SCDAA's mission is to advocate for people affected by sickle cell conditions and empower community-based organizations to maximize quality of life and raise public consciousness while advancing the search for a universal cure.