Dietary Factors as Causes of the So-Called Renal Leak of Calcium in Idiopathic Stone Formers
In 1972, Coe et al postulated the existence of a renal tubular leak of calcium to account for the hypercalciuria of some idiopathic stone formers1. More recently, it has been suggested that such patients have an overall defect in the proximal tubular reabsorption of fluid and electrolytes2. To shed more light on this controversial topic, we have examined the question as to whether or not the apparent renal leak of calcium is due to dietary factors, or to some general renal tubular dysfunction.
KeywordsFractional Excretion Idiopathic Hypercalciuria Renal Tubular Dysfunction Renal Tubular Function Medullary Sponge Kidney
Unable to display preview. Download preview PDF.