The state and county will spray for mosquitoes in parts of Camp Hill on Monday.
It will take place in the evening and involve a truck-mounted sprayer releasing a mist of pesticide at a rate of 0.75 ounces per acre. The pesticide has "very low toxicity" and "negligible" impact on other animals and the environment, a news release said.
The effort will focus on mosquitoes carrying West Nile Virus, which can cause illness and, in rare cases, death among humans.
It will take place in residential and park areas with high populations of mosquitoes; the news release didn't name specific locations.
West Nile Virus has been found in mosquitoes in about half of Pennsylvania counties this year, including Cumberland, Dauphin, York, Perry, Adams, Franklin, Berks and Lancaster counties, according to the state.
The state and counties collaborate on a program to track the spread of West Nile and control mosquitoes.
The public is urged to help by eliminating standing water where mosquitoes can lay eggs. This can include bodies of water as small as old cans and tires that fill with rain water.