Flashcards in W22-L9: DNA diagnosis of neurological disorders Deck (7):
What characterises unstable repeat expansions?
an expansion of a segment of DNA (usually 3 or nucleotides) within the specific gene
What is anticipation?
Expansion size increases onset in following generations and is associated with earlier onset/greater severity of symptoms
What is a mechanism of expansion?
What is the inheritance of Huntington Disease?
What is the inheritance of Spinocerebellar Ataxias?
What is the inheritance of Friedrich Ataxia?