Islamist terrorism: Who's to blame?
It happens after every major terrorist attack by Islamist terrorists in a Western country: the familiar debate about who is really to blame for this phenomenon. One side trots out the weary old trope that the terrorists simply "hate our values," and the other side claims that it's really the fault of Western governments for sending their troops into Muslim countries.
There's a national election campaign underway in Britain, so the ghastly Manchester bombing last week has revived this argument. It started when Labour leader Jeremy Corbyn (who voted against the invasion of Afghanistan in 2001, the invasion of Iraq in 2003, and the seven-month bombing campaign that overthrew Libya's dictator Muammar Gaddafi in 2011) made a speech in London on Friday.
"Many experts, including professionals in our intelligence and security services, have pointed to the connections between wars our government has supported or fought in other countries and terrorism here at home," he said.
In a later clarification, Corbyn added: "A number of people since the interventions in Afghanistan and Iraq have drawn attention to the links with foreign policy, including (British foreign secretary) Boris Johnson in 2005, two former heads of MI5 (the Security Service), and of course the (parliamentary) Foreign Affairs Select Committee."
With Labour catching up with the Conservatives in the polls, Prime Minister Teresa May leapt at the chance to twist Corbyn's words and all but accused him of treason. "Jeremy Corbyn has said that terror attacks in Britain are our own fault... and I want to make something clear to Jeremy Corbyn and to you: there can never be an excuse for terrorism, there can be no excuse for what happened in Manchester."
Boris Johnson chimed in: "Whatever we do, we can't follow the logic of the terrorists and start blaming ourselves or our society or our foreign policy. This has been caused not by us — as Jeremy Corbyn would have us believe — it's been caused by a sick ideology, a perverted version of Islam that hates us and hates our way of life." It's the old political trick of deliberately mistaking explanation for justification.
But both sides in this argument are wrong. The"Salafi" extremists who are called "Islamists" in the West (all of them Sunnis, and most of them Arabs) do hate Western values, but that's not why they go to the trouble of making terrorist attacks on the West. And it's not because of Western foreign policies either: there were no major Western attacks on the Arab world in the years before the 9/11 atrocity in 2001.
There had been plenty of attacks in the past: the Western conquest of almost all the Arab countries between 1830 and 1918, Western military support for carving a Zionist state out of the Arab world as the European imperial powers were pulling out after 1945, Western military backing for Arab dictators and absolute monarchs ever since.
The West turned against one of those dictators, Iraq's Saddam Hussein, after he invaded Kuwait, but it had the support of most Arab countries when it drove him out of Kuwait in the first Gulf War in 1990-91. And between then and 9/11 the West did nothing much to enrage the Arab world. Indeed, it was even backing the Palestinian-Israeli "peace process," which looked quite promising at that time.
But there was violence in many Arab countries as Islamist revolutionaries, using terrorist tactics, tried to overthrow the local kings and dictators. Up to 200,000 Arabs were killed in these bloody struggles between 1979 and 2000, but not one of the repressive regimes was overthrown. By the turn of the century it was clear that terrorism against Arab regimes was not working. To win power, the Islamists needed a new strategy.
The man who supplied it was Osama bin Laden. He had missed out on the long terrorist war in the Arab countries because he went to Afghanistan to fight a Soviet invasion in 1979. But in Afghanistan he fought in a war that Islamists actually won: having lost 14,000 dead, the Russians gave up and went home in 1989. The Afghan Islamists (the Taliban) came to power as a result.
Bin Laden realized that this could be a route to power for the Islamists of the Arab world as well: provoke the West to invade Muslim countries, lead the struggle against the Western occupation forces — and when the Western armies finally give up and go home (as they always do in the end) the Islamists will come to power.
That was why he founded al-Qaeda, and 9/11 was intended to sucker the United States into playing the role of infidel invader. Western governments have never recognized this obvious fact because they are too arrogant ever to see themselves as simply the dupes in somebody else's strategy. Their foreign policy error was to fall for bin Laden's provocation hook, line and sinker — and they are still falling for it 16 years later.


Is JEB Defecting from the Plutocracy?
Plutocrats bought one good political tactic for their over a hundred-million-dollar investment in Jeb Bush. Jeb's operatives who had him opposing the reviled Citizens United decision on the day before the New Hampshire primary earned their fee. A soundbite associating Bush with opposing Citizens United made Jeb appear to be the only Republican to contest Trump for support from the trans-partisan majority of voters who oppose the Court-created systemic corruption of politics. The timing worked. There was insufficient time before the primary for critics to analyze and explain how Bush's plan is far worse than Citizens United.
But let's try anyway, before he or another candidate uses the same ploy again.
The headline in The Hill for the day of the primary read: "Bush says he'd 'eliminate' Citizens United."
Wait a minute, one paused to ask. Is that "JEB," John Ellis Bush, brother of George W, scion of the Bush-Walker line of Wall Street plutocrats going back to Prescott? Jeb the high dollar candidate of 2016, the run-away winner of the normally decisive money primary? Yes it is.
Then he cannot possibly be talking about eliminating the notorious Supreme Court decision, the one widely marketed as the fount of all things plutocratic. Maybe he's instead talking about eliminating the right-wing plaintiff organization, Citizens United, for supporting an opponent in the primary? Nope.
But they seem to not like him now, whatever they thought before. Citizens United's president since 2000, David M. Bossie, quickly released a statement that Jeb "has embraced the left's view of the First Amendment. Jeb Bush now agrees with Hillary Clinton and Bernie Sanders to limit free speech in America." That gives Hillary a bit too much credit. But such is the Machiavellian complexity of systemically corrupt politics that one cannot know whether Bossie was paid by Bush to say that, or actually meant it, thinking it would somehow hurt Bush in the polls to distance him from plutocracy.
If Bossie is right, that would certainly be a newsworthy conversion experience. Did a Bush who was the leading beneficiary of plutocratic corruption in 2016, not to mention the rest of his life, really exit the family plutocratic rathole for the disinfection of sunshine, and find anti-corruption religion on the road to Manchester?
There are two issues that must be understood to analyze this apparent apostasy from Bush-family values.
First, Citizens United on close inspection is really not what it has been hyped up to be by professional activists.
Second, what Bush has really recommended is not so much to "eliminate" the corrupt Citizens United, but rather to legalize the far worse de facto regime that the case enabled, in the hands of Obama.
Citizens United is really two different decisions. One is a narrowly legal determination of the rights of the parties. The other is broadly political and therefore inherently illegitimate, "symptomatic of judicial overreach all too common on the current Court," as charged by one of the country's leading constitutional lawyers.
The judiciary is supposed to decide cases, which is what the legal part of the Citizens United decision did. But the political part of the decision illegitimately announced a set of broad new political principles to govern future cases, as applied most notably in Arizona Free Enterprise Club (2011) and McCutcheon (2014).
The proposition for which many liberal Democrat organizations have raised money, commonly to cover the costs of raising even more money, is that a constitutional amendment is needed to overturn Citizens United. Put aside for now the over-simplistic advocacy of the single most difficult policy tool in American jurisprudence, as if it were prerequisite for reforms already permitted under the current unamended Constitution. Here we are only assessing Citizens United as the recommended object of such albeit counterproductive advocacy, when all available political energies should be directed at dismantling Buckley v Valeo (1976).
It was Buckley that first established, with empty shell-game logic, that money is speech. It is that doctrine the Supreme Court invariably uses as its foundation to construct its every interference with campaign finance law, including Citizens United. Overturn Buckley and all the Court's corrupting decisions fall. But eliminate only Citizens United?
"Eliminating Citizens United" by law, or amendment as Bush proposed, could have a very narrow effect. It would not overturn Buckley. Thus, overturning Citizens United would not "embrace the left's view of the First Amendment," which sees Buckley's equation of money with speech to be a judicial scam. The majority which places democratic values above libertarian capitalist ideology knows that money is not speech.


I hate my girlfriends nose piercing, what am I supposed to say?
I'm in a pretty new relationship with my girlfriend. She is absolutely stunning and gorgeous the only think I disliked about her from the get go was her nose piercing. I takes so much away from the beauty of her face but I ignored cause it's not a real part of her body.
She constantly keeps asking how I like her piercing lately and I always get out of answering but I don't wanna lie to her.
Can I tell her I hate it and I feel like she would look way better without it?
I personally love jewellery on women. Nose piercings, ear piercings and chains. These make a girl look cute and extremely beautiful. Not that a girl is not beautiful without them. But these ornaments are worn by girls mostly, to "impress" their lovers. Otherwise, why would girls take so much effort in putting on make up and on top of that, wear all sorts of special jewellery?
Well, if you don't like it on her. Then you should just tell her that, you would love her even if she doesn't wear that piece of metal on her nose. Tell her how she looks beautiful without it. Just express your feelings in a smooth way.
Sorry for not being of much help.
What color do you or would you dye your hair? Does/Did Your School Have A Strict Dress Code? White on white yay or nay? What's your height gagers? Is Nicki Minaj attractive?
Well, i'd tell her in the nicest way possible. I'm not good at lying about things like that and I agree - nose piercing doesn't seem very attractive. Its like a dent in a car. The good news is eventually it will heal up if she stops wearing it. At least its not a tattoo.
She probably knows you don't like it which is why she's asking you but I think it's stupid that it bothers you so much. Obviously she likes it or she wouldn't have had it done. Leave her alone or find a girl without one.
"Hey, babe. I think you look a lot better without the nose piercing but that's just my opinion. I support you either way." Something like that.
It's not like she's going to hate you for saying such.
She asked for your opinion. Be honest with her, and tell her it makes you sad that she would do that to herself.
I wouldn't tell her it "makes you sad". That's a bit much.
Communication is one of the keys in a relationship. Just tell her and tell her why. She'll understand.
You can say that but recognize that it's her face not yours and you liking it or not likely won't make a difference.
You should probably be honest about it, but don't necessarily expect her to change it for you.
Next time she asks just tell her you think she'd look better without it...Just be honest.
"u looke better w/o it"
Say you prefer her without it.
Why be insecure? Not everyone can “love themself” This is How Beauty Standards Differ Around the World What It's Really Like to Be an "Ugly Woman" 10 Benefits to Why a Girl Shall Stay Virgin Until Marriage!
Home > Fashion & Beauty > I hate my girlfriends nose piercing, what am I supposed to say?


Multinationals with large and complex production networks have become a dominant feature of today's economies. But while their supply networks are large, this does not mean that they own every step of the global production chain. This column examines French firms' decision whether to source imported inputs from independent suppliers or from affiliates. The results show that multinationals typically own and source from international suppliers that provide technologically important inputs—that is, those that account for a high share of costs.
Global flows of foreign direct investment (FDI) have been steadily increasing in recent decades, resulting in the presence of large multinationals spanning global production networks. Most notable has been the recent growth in Chinese takeovers around the world. For example, China's HNA Group (of which Hainan Airlines is a part) bought Swiss-based airline caterer Gategroup as well as Swiss aircraft maintenance organisation SR Technics. Overall, the share of non-OECD economies in global outward FDI has increased by a factor of 25 since 2003 (OECD 2015).
Companies tend to source technologically important inputs—that is, inputs with a higher cost share, from subsidiaries; by contrast, they tend to buy less important inputs from independent suppliers.
In Figure 1, we split the inputs of French companies into two groups: one denoting the most important (above median cost share) inputs, and the other the least important (below median). We plot the shares of intra-firm (outsourced and mixed) imports for each group and a clear pattern emerges—firms are more likely to source more important inputs from their affiliates (larger intra-firm import share).
The fact that multinationals typically produce important inputs in-house suggests that their main motive for owning a supplier is to prevent it from haggling over prices and to facilitate coordination. Interestingly, however, sourcing from affiliates is even more likely whenever the provision of an intermediate input is subject to a good contracting environment, contrary to what would be expected in a TCE world (i.e. that if contracts can ensure that suppliers act in line with the multinational's desires the need for integration would be reduced, rather than reinforced).
Similarly, we find that whenever a downstream multinational has to invest a lot in the supply relationship—for example, in the form of dedicated machinery or R&D—technologically important inputs are also more likely to be produced in-house. It is unclear how this empirical pattern can be explained by haggling and coordination alone.
How can we make sense of these findings, including the main tendency to vertically integrate important suppliers? We argue that they are in fact quite naturally in line with a world in which TCE-type forces (pushing for integration of important inputs) coexist with and, on average, overpower PRT forces (pushing for outsourcing). When the contracting environment is better or when a multinational's investments matter more, PRT considerations are less of a concern and important inputs are even more likely to be produced in-house.
Multinationals with large and complex production networks have become a dominant feature of today's economies. But while these supply networks are large, it does not mean that multinationals own every step of the global production chain. Understanding the determinants of the ownership boundaries of multinationals is important since this has implications for how closely the economies of different countries are interconnected. For example, multinationals might transfer knowledge to their subsidiaries but not to independent suppliers; there might be effects on the wages paid to workers, as multinationals tend to pay higher wages than domestic firms; and it might also matter for how economic crises spread to other economies. Our research suggests that policymakers should analyse global production networks specifically in terms of the most important inputs that are used in each production chain.
This article first appeared on www.VoxEU.org on February 5, 2019. Reproduced with permission.
Berlingieri, G, F Pisch and C Steinwender (2018), "Organizing Supply Chains: Input Cost Shares and Vertical Integration," CEP Discussion Paper 1583.
Bernard, A B, J B Jensen, and P K Schott (2006), "Transfer Pricing by U.S.-Based Multinational Firms," mimeo.
Grossman, S J, and O D Hart (1986), "The Costs and Benefits of Ownership: A Theory of Vertical and Lateral Integration," Journal of Political Economy 94(4): 691-719.
Hart, O D and J Moore (1990), "Property Rights and the Nature of the Firm," Journal of Political Economy 98(6): 1119-58.
Klein, B, R G Crawford and A A Alchian (1978), "Vertical Integration, Appropriable Rents, and the Competitive Contracting Process," Journal of Law and Economics 21(2): 297-326.
Klier, T H, and J M Rubinstein (2010), "Measurement Issues Arising From the Growth of Globalization," Conference Paper.


The need to caulk aluminum siding may be related to different factors, however the way to do the caulking remains the same. Regardless of whether you are fixing a dent, a small hole, cracks or are caulking around windows and doors, the way to apply the caulk never changes. When you caulk your aluminum siding you will be accomplishing two things. The first is that you can then paint your home and it will look new again. The second is that it will help to keep the home warmer in the winter due to fewer drafts, a huge plus in colder climates.
Locate the areas that need to be caulked. This will vary, however, common issues that can be fixed by caulking aluminum siding are dents, small holes and cracks. For homes that are drafty this might be around windows and doors or the seams of the aluminum siding itself.
Prepare the aluminum siding for caulking. Make sure there is no dust, grime or dirt where you will be applying the caulk. Use a dry rag to brush away any loose paint, dirt or grime. If you are replacing old caulk around windows and doors, you will need to remove it first. Use the utility knife to separate the caulk from the siding and then rub with sandpaper until smooth. Use a rag to brush away any debris before caulking the aluminum siding.
Pull the plunger on the caulking gun as far out as it will go if using a caulking gun. The teeth on the plunger will need to be facing upward with the trigger facing downward; this is done by just twisting the plunger. Place the tube of caulk in the gun, twist the plunger so the teeth face down and begin to squeeze the trigger until the plunger hits the tube of caulk.
Cut a hole in the tip of the caulking tube on an angle. The hole size depends on your project and the tip shows where to cut for different sizes. It is best to start with a small hole first and then make it larger if need be. This is the same regardless of the type of caulk being used.
Puncture the foil seal on the tube of caulk. Most caulking guns will have a wire built onto them to do this.. A squeeze tube would have a point built into the cap. If your caulk has neither of these you can use a coat hangar to puncture the foil.
Pull the trigger of the caulking gun or squeeze the tube of caulk to fill cracks and dents. While squeezing the trigger or tube of caulk just move the tip of the tube to distribute the caulk evenly. This will take some practice, so before you start caulking siding, practice on a rag or maybe an area of the aluminum siding that is not noticeable.
Smooth the caulk. Wet the rag and squeeze well. Wet your finger and use your finger to smooth the caulk in the crack or dent in the aluminum siding. For a larger dent you may want to use a putty knife dipped in water to smooth the caulk.
Clean your finger or the putty knife off on a rag to remove the excess caulk. Repeat as needed until the dent or crack looks how you want it to. Allow to dry per the caulk manufacturer's instructions before painting.
Caulk around windows or doors connected to your aluminum siding by pressing the tip of the tube into the crack and moving the tip in a straight line from one side to the other. Pull the trigger on the caulking gun or squeeze the tube of caulk as you go.
Wet your finger and press the caulk into the gap between the window or door and the aluminum siding and pull your finger right across the gap, wiping your finger off on the wet rag as you go. Rinse the rag in the water when necessary. Allow the caulk to dry per the manufacturer's instructions before painting.
When caulking siding it is important not to use too much caulk. As long as the gaps and tiny cracks are filled there is enough caulk.
When only caulking small areas, a squeeze tube should be sufficient. If caulking several windows as well as a couple doors, however, you will likely want to use a caulking gun.
When caulking siding always wait until the caulk is dry before painting.
Check the forecast to make sure it won't be raining in the next couple days to be sure the caulk will not get wet before it is completely dry.


Crafting for boys is always a tricky one. Make them feel just as special for their birthday, by creating a unique handmade card for boys of all ages!
1. Lay strips of printed Washi tape diagonally across the front of your card blank leaving two blank strips the same width as the height of the sticky alphabet letters.
2. Trim off any excess Washi tape with scissors to leave a sharp neat edge all around the card.
3. Lightly arrange the alphabet stickers on to the card. When you are happy with their position press firmly in place.
1. Choose a section of blue coloured cards. Use a craft knife and metal ruler to cut a 15 x 2 cm strip from five different colour cards.
2. Position the strips on to the front of the card blank leaving enough space at the base of the card for your message. When you are happy with their position, glue in place. Trim off any excess card.
3. Lightly position the alphabet stickers to create your chosen message. When you are happy with the layout, press the stickers firmly in place.
1. Print the Guitar template and enlarge to desired size. Use scissors to carefully cut out the template. Put to one side.
2. Use a craft knife and metal ruler to cut a rectangle of bark blue card. Make it 1 cm smaller than the dimensions of the blank card. Position this centrally on to the blank card and lightly mark the position in pencil. Glue the card in place, lining it up with the pencil markers. Gently erase the pencil markings.
3. Take a sheet of plain white paper and stick lengths of the red patterned Washi Tape to form a rectangle shape that is the height and width of the guitar outline. Take time to line up each strip of Washi Tape to ensure there are no gaps in-between each strip.
4. Flip over the sheet of white paper with the Washi Tape strips on it so that the reverse side is facing up. Take the guitar template and draw around the outside on to the reverse side of the stuck down Washi tape strips.
5. Use scissors to carefully cut out the guitar. Lay the guitar on to the front of the card and when you are happy with its position, glue it in place.
6. Add gem stickers for the guitar tuning pegs to add a bit of sparkle.
1. Print the Sports Car template and enlarge to desired size. Use scissors to carefully cut out the template. Put to one side.
2. Use a craft knife and metal ruler to cut a square of black card. Make it 5 mm smaller than the dimensions of the blank card. Position this centrally on to the blank card and lightly mark the position in pencil. Glue the card in place, lining it up with the pencil markers. Gently erase the pencil markings.
3. Take a sheet of plain white paper and stick lengths of the gold patterned Washi Tape to form a rectangle shape that is the height and width of your sports car outline. Take time to line up each strip of Washi Tape to ensure there are no gaps in-between each strip.
4. Flip over the sheet of white paper with the Washi Tape strips on it so that the reverse side is facing up. Take the sports car template and draw around the outside on to the reverse side of the stuck down Washi tape strips.
5. Use scissors to carefully cut out the sports car. Lay the car on to the front of your card and when you are happy with its position, glue it in place.
6. Use ‘thickers’ alphabet stickers to write your personalised Birthday message.
7. If desired, add two gem stickers to the centre of the car wheels for a bit of sparkle.


How to make solar panels? or, is it difficult to build solar panels?, they are questions that can one get done after knowing the high price of new photovoltaic panels. Is it better to buy solar panels used?. Both possibilities, the construction and the second hand panels are good choices. The decision should not be taken lightly because it depends on the efficient and lasting operation of an installation of photovoltaic panels. I then briefly detail my analysis of both possibilities through the search and study of the options available on the internet. Buy solar panels used.This seems the most logical option after discarding the purchase of new panels. There are a variety of prices, brands and qualities which makes it possible to choose the most appropriate to our needs. This wide range of offer is very good, but on the other hand it may present a certain complication.
It is necessary to know the technical foundations of the generation of solar energy to make a good choice and purchase. Be carried away by an excellent price without rigorously check the status of operation of the panels should be avoided. Construction of solar panels.It may seem strange, but to build photovoltaic panels need not be technical. These devices are surprisingly simple and there are many manuals, guides and instructions available for their construction. The great advantage is that a panel made in house is built with new parts at a price much lower than that of a used panel. The disadvantage is obvious, desire and time are needed to undertake this work. My decision.I prefer new products, especially in the case of electrical devices, due to this and the low costs involved I decided to build my own photovoltaic panels.
It would like to now share the results of my search, wishing that this information is helpful for those who want to switch to clean energy and significantly reduce their costs of energy supply. A good summary of that is in the link I put below It is in my opinion the best existing option in terms of photovoltaic systems construction. It is a professional guide with step by step videos designed so anyone can follow the instructions, regardless of the lack of technical knowledge or the level of English.


Dynamin 1. Our recognition of DNM1 encephalopathy as a novel disease started out as a digital flicker. Deep inside some of the large-scale studies in epilepsy genetics, there were a few patients with de novo mutations in the gene coding for DNM1. However, amongst all the other likely and less likely candidates, it took a while for DNM1 to emerge as a true candidate. But even then, being a disease gene born out of large-scale studies with little information on clinical presentation and disease course, we had learned little about how patients with DNM1 encephalopathy actually present and how they develop over time. In our recent publication in Neurology, we describe the spectrum of DNM1 encephalopathy, including an unusual mutational landscape and the first genetic cause in a patient with FIRES.
Dynamin 1. Most of the disease-causing mutations in DNM1 cluster in the GTPase domain, where they affect the GTP-catalyzed multimerization of DNM1 that leads to synaptic vesicle fission. These mutations have a dominant-negative effect, suggesting that the altered DNM1 protein affects the function of the remaining DNM1 protein.
Dynamin 1 function. When synapses release their neurotransmitters, they rely on a sophisticated machinery that initiates and completes the fusion of the synaptic vesicle. Many of the newly discovered genes for neurodevelopmental disorders including STXBP1, SNAP25, STX1B, and CPLX1 encode proteins that are involved in this machinery. However, once vesicle fusion is completed, the neuron encounters a fundamental biophysical problem. With every fused synaptic vesicle, the surface of the presynapse increases slightly. Therefore a mechanism is needed to recycle synaptic vesicles. This is where the dynamin 1 protein comes in. Dynamin 1 molecules form a noose around the base of the vesicle that is is drawn tighter and tighter until the vesicle pops off – this mechanism is called vesicle fission. This should not be confused with vesicle fusion, which describes the step of merging the vesicle with the presynapse. Dynamin 1 basically acts as a molecular scissor. In order to generate sufficient force to complete this task, Dynamin 1 is dependent on the hydrolysis of GTP. Mutations in DNM1 that we have seen in patients often affect the GTP-binding domain and lead to a dominant-negative effect.
The DNM1 spectrum. Overall, we were able to include 21 patients with pathogenic (most de novo) mutations in DNM1 in our study. 19/21 patients had epilepsy, which was difficult to treat in most patients. Infantile Spasms starting at the age of around six months were the most common presentations of DNM1 encephalopathy. Only two patients in our study became seizure-free, including one patient who became seizure-free on clobazam and one patient who became seizure free on the ketogenic diet. Of the subset of patients who we followed into young adulthood, all patients continued to have drug-resistant epilepsy. This feature differentiates DNM1 encephalopathy from many other genetic epilepsies as only few genetic epilepsies show such a protracted course over time.
The genetic landscape. When we looked at the mutational landscape of DNM1 encephalopathy, we were surprised to find that a single mutation (p.Arg237Trp) accounts for approximately one-third of patients. Given that our previous studies indicated that DNM1 encephalopathy accounts for up to 2% of patients with Infantile Spasms or Lennox-Gastaut Syndrome, this suggests that this single mutation is actually one of the most common mutations in refractory epilepsies. In our study, we found a good explanation for this restricted mutational spectrum. The p.Arg237Trp mutation directly affects the GTPase domain of DNM1, leading to a dominant-negative effect. Basically, the mutated dynamin 1 affects the molecular noose function of the remaining, non-mutated protein. Given that this mutation introduces a block in dynamin 1 function, we speculate that this single mutation may be an interesting candidate for novel therapeutic strategies such as gene therapy approaches. In contrast to many other genetic epilepsies where the disease mechanism is due to haploinsufficiency, dynamin 1 encephalopathy is due to an altered function of the mutated dynamin protein that results in a predicted block of dynamin 1 function.
The outliers. Even though the phenotypic landscape of DNM1 encephalopathy is more homogeneous than initially expected, we identified a few outliers in our study. Two patients with pathogenic DNM1 mutations did not have seizures, but presented with developmental delay only. Many neurodevelopmental disorders have a broad phenotypic range and for most neurodevelopmental disorders, presentations without epilepsy may be quite common. Therefore, we were not surprised that DNM1 encephalopathy has a similar spectrum. However, when we checked our DNM1 phenotypic landscape against data from other studies, we were surprised at how common epilepsy in DNM1 patients is. In the most recent publication from the DDD study, which included >7500 individuals with broad developmental disorders, the authors identified 5 nonsynonymous de novo DNM1 mutations. Human Phenotype Ontology (HPO) terms were provided for these individuals, but detailed phenotypic information was not available. In this cohort, also 4/5 patients with DNM1 mutations had HPO terms that include seizures, suggesting that the vast majority of patients with DNM1 patients in cohort of patients with broader neurodevelopmental disorders have epilepsy. In addition, one patient with a novel DNM1 mutation had FIRES (Febrile infection-related epilepsy syndrome) starting at the age of four. FIRES is a catastrophic epilepsy syndrome that is thought to have a genetic basis, which still remains elusive. We have screened known candidate genes for FIRES and are currently coordinating a larger exome-wide study, but to our knowledge, this is the first patient with a known genetic etiology.
What you need to know. In summary, DNM1 encephalopathy is a novel genetic epilepsy syndrome that is typically characterized by therapy-resistant epilepsy starting with Infantile Spasms at the age of 5-6 months. In contrast to many other epilepsy syndromes, DNM1 encephalopathy leads to therapy-resistant epilepsy over time, which makes this disease an candidate for orphan drug development. The mutational spectrum of DNM1 encephalopathy is relatively restricted and up to one-third of patients carry a single, recurrent mutation. A dominant-negative effect of the mutated dynamin 1 protein is the pathogenic mechanism behind DNM1 encephalopathy.
Disclosure/Open Access. We typically disclose on our blog when our posts may be biased. As I am the senior author on our current publication, this blog post is therefore not an objective review of our publication, but a commentary on our recent work. Our Neurology publication on DNM1 encephalopathy is available as an Open Access publication. We also previously featured DNM1 encephalopathy in our blog posts in 2014 and 2015.
This entry was posted in 2017, DNM1 and tagged DNM1. Bookmark the permalink.


If I had my choice of perfect worlds, there would be no government in it. People purchase protection from a private company of their choice. This company, in turn, subscribes to a system of laws which is privately written. Independent judges interpret the law fairly, or they don't get the business next time. Some legal systems will come into conflict, which will be resolved by a payment in one direction or another. The price one pays for a legal system determines the amount of conflict one bears. Poor people obviously get a cheap one which doesn't allow for much conflict. But it does cover them against the essentials -- no murder, no theft. In the end they get more justice by buying it in an efficient market than what they're currently getting through government -- arguably less than zero.
There's a lot of reasons to expect that this would result in better laws.
Obviously, in my perfect world, some parents still hurt their own children, so there must be provision in people's laws to protect children against their parents as well as others. And equally obviously, some people will seek to employ inordinate violence against their attackers, so there must be provision in people's laws against that as well. How do I know that these provisions will be there? Because people will purchase a subscription to a legal system without knowing whether it will be used for or against them. So, they will shop carefully. Will they make mistakes even though I'm supposing a perfect world? Sure they will. But the mistakes come from their own choice of legal system, and they have the power to correct that.
None of us has the power to correct our governmental legal system single-handedly. A private legal system, on the other hand, would quickly triangulate on what the majority desire for justice. The legal systems that gave out the justice that most people wanted would be cheapest, which would tend to bring in people from the sidelines to the same majority legal system. In practice most legal systems would be very similar to each other, and would be very close to optimal. This should be contrasted with the current governmental systems, which tend to produce laws optimized for special interests.
If you want an example of how this might work, take an extremely difficult example -- abortion. Clearly many people want the freedom to abort their babies. Many people also think that's murder. They would each choose legal systems that allowed or disallowed abortion. How, then, would these legal systems work? How could you both allow and prohibit abortion?
Let's follow an example. A woman gets pregnant and decides to carry the baby to term. Fine. She's not disobeying anybody's laws. Let's say that she decides to have an abortion. Obviously she hasn't chosen the anti-abortion legal system. She would contract with a doctor for an abortion. However, the pro-choice legal system has been paid to include a term that says that an anti-abortion protection firm will be informed of such a contract. Maybe the woman doesn't like this very much, but she chose that system, and besides it made her legal system cheaper. Now the anti-abortion firm knows that she's serious about getting an abortion. They offer to buy her all the medical care she needs to deliver the baby, and will find parents willing to adopt the baby.
Now here's where it gets tricky. Exactly what happens depends on exactly how many people are in favor of abortion choice and how much they're willing to spend to get their way. Let's say that the anti-abortion people are in the minority. They won't have the resources to help every women, but they'll have it for some, as many as possible. So, even though they're in the minority, they'll get their way more often than they do now.
Let's suppose it's the other way around -- that the pro-choicers are in the minority. It's likely that their legal system will be more expensive, because it includes the choice of abortion. It also requires them to seek counselling before getting an abortion. It also imposes a mandatory 7-day waiting period. Both of these were purchased by the anti-abortion majority, who have large resources at their disposal. A license to have an abortion might cost some serious amount of dollars.
Do poor people get screwed by a private market for law? Yes, absolutely, no question about it. If they weren't screwed, you'd have a hard time calling them "poor", or saying that "poor" was a bad thing to be. The harder question to answer is whether they are screwed more or less under a system of governmental legislated law as under a system of purchased private market law. At least under private law, somebody can purchase a subscription and donate it to them. If you think nobody would do that, you must first take your magic wand and wave away the existance of the Carnegie libraries.
In this manner, through a market for law, you have people purchasing, not voting for, law systems. To the extent that they purchase non-controversial, majority law, it's cheap. If they want to do something most people disagree with, it costs them money, and not many people can afford to do it. Contrast this with the current system where every man has a vote regardless of how strong he feels about the subject, and every decision is decided regardless of how many people feel strongly about it.


On the White Album, John Lennon and The Beatles famously asked that question, and over the last two years or so the champions of enterprise social networking have been quick to proclaim an answer in the affirmative. It’s been too easy to claim that introducing newsfeeds, microblogging, @targets and #tags to the enterprise represents some sort of revolution in the way organizations communicate. It doesn't. If anything, it’s an evolution, not a revolution -- but the pieces are in place to get there in the near future.
For all the sound and fury about enterprise social networks breaking down barriers and providing a better communication forum, in many ways they’re just a new channel for something people have been doing since time immemorial -- talking with one another. In business, the channels have grown as society’s grown.
Face-to-face conversation and written letters were replaced with paper memos and pneumatic tubes to carry them between floors of turn-of-the-century office towers. These in turn were replaced by telephone calls, which led to dictation, answering machines and voicemails. Some twenty years ago, the growth of the internet allowed email to begin exploding into mass adoption beyond the closed networks of corporate systems. All of these advancements were simply that -- new technology, admittedly groundbreaking, but the use case was always the same. Person A needed to talk to Person B. And usually, Person A already knew Person B.
The promise of enterprise social networks is that they will leverage the power of the network to engage other users in that conversation. In theory, when Person A and Person B are having that dialogue on a social network, now Persons C, D, E, F ad nauseam can swoop in and participate. They’ll know it’s happening because @targets and #tags serve it up as something they’re interested in, and it adds value because the knowledge in people’s heads is (presumed to be) a corporate asset; now that knowledge is out of their heads, interacting with others’ knowledge, and producing all sorts of new connections and leaps of logic that lead to innovation. It’s Wikinomics on speed.
When users are engaged with a conversation, it’s because they care about it. Maybe it’s the people they’re talking with, maybe it’s the topic they’re discussing, or maybe it’s both. The point is, people engage with documents, data and especially other people on social networks because it’s something that intrinsically matters to them. That means people and issues close to home. People and issues they can engage with. That’s not something you can create, it’s something you have to tap into.
This was true with letters and written memos. It was true with the phone. It was (and remains) true with email. It hasn't stopped being true with enterprise social networks. In enterprises, adoption of social tools most typically comes in fits and starts. Different departments engage different applications. Even when there’s a common platform -- which makes the most strategic sense -- getting an enterprise to adopt that platform across the board is hard. You need to have people who interact locally before they can add value by interacting globally.
Then you can start talking about truly enterprise social. And only when you've achieved a truly social enterprise can you start talking about revolutionary new applications of this technology, because a revolution is about doing something entirely new, not finding a new way to do something old.
Like any good revolution, the enterprise social revolution needs to start with a challenge, a tyrant to overthrow. In this case, it’s the proliferation of social tools within the enterprise, because in the next few years people will engage and will adopt them. I've heard it said that for a new tool to be adopted, it just needs to be easier to use than the old tool, and once you have an audience of engaged users, social networks are certainly easier than email.
The thing is, those tools won’t always talk to one another, and users will find themselves with just as much information to manage from various newsfeeds as they ever had with email. Just look at the options: Yammer, Chatter, Jive, Connections, et cetera, et cetera … and those are just the obvious ones.
The concept of a destination, an enterprise Facebook, has less apparent value than it did even a year ago.
The sheer amount of noise in an enterprise has the potential to eventually overwhelm key messages. Just like a stack of paper. Just like voicemails. Just like email. Where enterprise social needs to truly deliver and yes, believe it or not, revolutionize (for once) how we communicate is through aggregation.
Bring the messages together, filter them and be smart enough to ferret out the important stuff for immediate consumption. Use powerful search-driven applications and personalization algorithms to make it a sound bite, a capsule, an executive summary -- a Twitter-length 140 characters -- that decision makers can absorb in the blink of an eye and act on through integrated messaging from the same window. Nobody ever found an efficient and user-friendly way to do that with paper, voicemails or email -- short of having an assistant sort through them all, and the “assistant-for-every-knowledge-worker” model clearly wouldn't scale.
Do something that’s never been done before? Now that’s revolutionary. That’s more like what we want to see from this new technology, not slicker ways to do the same old things.
You say you want a revolution? Let’s see enterprise social get there by 2015, and we can talk. It’s definitely coming. If you know where to look, it’s already here.


This operator is used for performance evaluation. It delivers a list of performance criteria values. These performance criteria are automatically determined in order to fit the learning task type.
In contrast to the other performance evaluation operators like the Performance (Classification) operator, the Performance (Binominal Classification) operator or the Performance (Regression) operator, this operator can be used for all types of learning tasks. It automatically determines the learning task type and calculates the most common criteria for that type. For more sophisticated performance calculations, you should use the operators mentioned above. If none of them meets your requirements, you can use Performance (User-Based) operator which allows you to write your own performance measure.
This input port expects a labelled ExampleSet. The Apply Model operator for example provides labeled data. Make sure that the ExampleSet has a label attribute and a prediction attribute. See the Set Role operator for more details.
This is an optional parameter. It requires a Performance Vector.
This port delivers a Performance Vector (we call it output-performance-vector for now). The Performance Vector is a list of performance criteria values. The output-performance-vector contains performance criteria calculated by this Performance operator (we call it calculated-performance-vector here). If a Performance Vector was also fed at the input port (we call it input-performance-vector here), the criteria of the input-performance-vector are also added in the output-performance-vector. If the input-performance-vector and the calculated-performance-vector both have the same criteria but with different values, the values of the calculated-performance-vector are delivered through the output port. This concept can be easily understood by studying the attached Example Process.
This process is composed of two Subprocess operators and one Performance operator. Double click on the first Subprocess operator and you will see the operators within this subprocess. The first subprocess 'Subprocess (labeled data provider)' loads the 'Golf' data set using the Retrieve operator and then learns a classification model using the k-NN operator. Then the learnt model is applied on the 'Golf-Testset' data set using the Apply Model operator. Then Generate Weight operator is used to add an attribute with weight role. Thus, this subprocess provides a labeled ExampleSet with a weight attribute. A breakpoint is inserted after this subprocess to show this ExampleSet. It is provided at the labeled data input port of the Performance operator in the main process.
The second Subprocess operator 'Subprocess (performance vector provider)' loads the 'Golf' data set using the Retrieve operator and then learns a classification model using the k-NN operator. Then the learnt model is applied on the 'Golf' data set using the Apply Model operator. Then the Performance (Classification) operator is applied on the labeled data to produce a Performance Vector. A breakpoint is inserted after this subprocess to show this Performance Vector. Note that this model was trained and tested on the same data set ('Golf' data set), so its accuracy is 100%. Thus this subprocess provides a Performance Vector with 100% accuracy and 0.00% classification error. This Performance Vector is connected to the performance input port of the Performance operator in the main process.
When you run the process, first you will see an ExampleSet which is output of the first Subprocess operator. Press the Run button again and you will see a Performance Vector. This is the output of the second Subprocess operator. Press the Run button again and you will see various criteria in the criterion selector window in the Results Workspace. These include classification error, accuracy, precision, recall, AUC (optimistic), AUC and AUC (pessimistic). Now select accuracy from the criterion selector window, its value is 71.43%. On the contrary the accuracy of the input Performance Vector provided by the second subprocess was 100%. The accuracy of the final Performance Vector is 71.43% instead of 100% because if the input Performance Vector and the calculated Performance Vector both have the same criteria but with different values, the values of the calculated Performance Vector are delivered through the output port. Now, note that the classification error criterion is added to the criteria list because of the Performance Vector provided at the performance input port. Disable the second Subprocess operator and run the same process again, you will see that the classification error criterion does not appear now. This is because if a Performance Vector is fed at the performance input port, its criteria are also added to the output Performance Vector.
Accuracy is calculated by taking the percentage of correct predictions over the total number of examples. Correct prediction means examples where the value of the prediction attribute is equal to the value of the label attribute. If you look at the ExampleSet in the Results Workspace, you can see that there are 14 examples in this data set. 10 out of 14 examples are correct predictions i.e. their label and prediction attributes have the same values. This is why the accuracy was 71.43% (10 x 100 /14 = 71.43%). Now run the same process again but this time set the use example weights parameter to true. Check the results again. They have changed now because the weight of each example was taken into account this time. The accuracy is 68.89% this time. If you take the percentage of the weight of the correct predictions and the total weight you get the same answer (0.6889 x 100/1 = 68.89%). In this Example Process, using weights reduced the accuracy but this is not always the case.
Note: This Example Process is just for highlighting different perspectives of the Performance operator. It may not be very useful in real scenarios.


Raphael Esparza of Doc's Sports shares a Christmas Poem that he wrote about sports betting. Doc's Sports would like to wish all of our site visitors a very Merry Christmas and a Happy New Year, and let's all have a 2017 filled with happiness and sports betting profit.
Read more about Twas the Night Before Christmas (NFL/NBA Gambling Style).
It's the holiday season, and that means Disney is giving us another early holiday present. We are less than a month away from the worldwide debut of "Rogue One:A Star Wars Story", and this installment of the Star Wars movie franchise should be a mega hit. This new Star Wars movie has me puzzled because there has never really been a movie quite like 'Rogue One' on this scale, so putting betting numbers for this was actually a challenge.
Read more about Rogue One: A Star Wars Story Betting Odds From Expert Pop Culture Oddsmaker.
The Summer Olympics in Brazil ends on Sunday. However, if you need betting action on a different sporting event, how about WWE wrestling? Sunday night the biggest WWE PPV of the summer takes place at the Barclays Center in Brooklyn, and I can guarantee the crowd will be rowdy and energetic. After a pretty good Battleground PPV in July the WWE Universe is expecting a big night in Brooklyn, and I'm looking for big cash Sunday night at SummerSlam.
Read more about WWE SummerSlam Odds and Betting Predictions for Sunday PPV.
The 4th of July means the 4 Fs: Family, Fun, Food, and Fireworks! I would say that it's safe to add a fifth 'F': Famous! As in the Famous Nathan's Hot Dog Eating Contest on the 4th of July! Monday will mark the 100th edition of the contest in Coney Island, New York at the corner of Surf and Stillwell street.
Read more about Nathan's Hot Dog Easting Contest Betting Picks from Expert Pop Culture Handicapper.
Why? Every time I see the highlights of the Nathan's Hot Dog Eating Contest on July 4 I ask myself why in the world this exists. I once made the mistake of watching the whole contest. It's years later and I still haven't recovered. It's just plain disgusting - a spotlight for freaks. There are odds on it, though - I'll bet on the most disgusting humans on the planet if the price is right. So, is the price right? Let's take a look.
Read more about Nathan's Hot Dog Eating Contest Odds and Expert Betting Predictions.
It's never too early to start over thinking about the next season of "The Walking Dead", and for me it's never too early to lay some entertainment betting action. Season 6 ended with an epic cliffhanger as the character Negan with his baseball bat "Lucille" wrapped in barbed wire is getting ready to smash a major character to death.
Read more about Who Dies in the Walking Dead Season 7 Premier? Odds and Betting Predictions.
WWE's PPV Money in the Bank is live this Sunday from the T-Mobile Arena in Las Vegas, and this PPV will be so much better than the last big event. I still can't believe this will be the seventh straight year that the WWE has featured a match giving one guy a title shot if he wins the Money in the Bank match. We should see some great matches this Sunday with John Cena back, and of course the Money in the Bank match is always fun to watch. Money in the Bank usually sets up a great SummerSlam card, and feuds that start this Sunday could end at SummerSlam.
Read more about 2016 WWE Money in the Bank Odds and Expert Betting Predictions.
It's no secret that "Game of Thrones" is one of the hottest shows on TV and one of the most talked about shows on social media and at office water coolers and family gatherings and dinner with friends. The sixth season of Game of Thrones ends in two weeks, and the next two episodes are going to be epic and jaw-dropping. It's also no secret that we will see a huge shocking death in the next couple of episodes. Therefore, while we wait, let's lay some cash down on who will get the axe in the next couple of weeks of Game of Thrones.
Read more about Who will Die Next on Game of Thrones? Expert Predictions with Betting Odds.
If you are wondering why I didn't do a preview for WWE Payback (May 1) a couple of weeks ago, it's because I knew another PPV was only three weeks away! WWE PPV Extreme Rules is live this Sunday from the Prudential Center in Newark, and this PPV will be so much better than the last event.
Read more about 2016 WWE Extreme Rules Odds and Expert Betting Predictions.
I guess when the Mouse says don't tell anybody, you listen to that Mouse because boy did the entertainment world get a shock last week. After four years sitting beside Kelly Ripa, former New York Giants football star Michael Strahan has decided to part ways from "Live! with Kelly and Michael".
Read more about Odds for Michael Strahan's Replacement on "Live!" Morning Talk Show.
WWE PPV WrestleMania is live this Sunday from the AT&T Stadium in Arlington, Texas, and WrestleMania is the Super Bowl of wrestling entertainment. WrestleMania always brings out the entertainment stars, and this year ESPN Sports Center will be live at WrestleMania. We should see some great matches this Sunday, and I'm hoping we see more mind-blowing upsets like the last couple of years with Seth Rollins winning and two years ago with Brock Lesnar beating Undertaker.
Read more about 2016 WWE WrestleMania Odds and Expert Betting Predictions.
On Sunday, Feb. 28, 2016, the film industry, including actors and actresses alike, will descend on California to take part in the 88th Academy Awards ceremony at the Dolby Theater in Hollywood. It should be noted that even if you are not up to date with pop-culture news, you should know that this is Leonardo DiCaprio's world and we are all just living in it.
There's a lot of negative buzz surrounding the Oscars this year. However, set aside the negativity because there is outstanding value in this entertainment betting sheet. Live this Sunday is the 88th Academy Awards (Oscars) show at the Dolby Theatre in Hollywood, and we will see some underdog winners Sunday night. Our friends over at MyBookie have a full list of odds for the 88th Annual Academy Awards. Jump on these numbers now because these betting lines will move.
Read more about 2016 Oscars Picks and Expert Betting Predictions.
It's awards season and yes, all focus is on the 88th Academy Awards ceremony Sunday, February 28th. But the Saturday night before the Oscarshostsan even better awards night: the 35th Annual Razzies awards for the 'Worst' in movies and our friends over at MyBookie have posted odds for all categories.
Read more about 2016 Razzies Awards Odds and Betting Predictions.
I always tell people you can put odds up on anything and you will get action no matter what it is, and our friends over at 5Dimes haven't proven us wrong yet. Don't hate the messenger and don't tell me that I have a gambling problem because of what I'm going to throw down on this Super Bowl Sunday.
Read more about Bet on a True Underdog: Puppy Bowl Odds and Predictions.
Sunday night in Orlando at the Amway Center is the 2016 Royal Rumble, and what an event it will be! The first WWE PPV of the year will have excitement and outstanding betting opportunities, and I can guarantee we will see some unbelievable surprises.
Read more about 2016 WWE Royal Rumble Odds and Predictions for Sunday PPV.
It's that time of year again when the awards season starts, and the first one is the Golden Globes. Our friends over at MyBookie.ag were one of the first online books to release odds on the 73rd Golden Globe Awards. The Golden Globe Awards air live on Sunday, Jan. 10, 2016, and I know I will have lots of action on the Golden Globes betting board. Some of these categories have huge favorites, but they also have outstanding value. At this time I will show you the opening odds on the 73rd Golden Globes Awards and tell you if you should jump on some long shots or take the favorite.
Read more about 2016 Golden Globe Awards Betting Odds with Picks and Expert Predictions.


Why is a customer saying my short code is expired, blocked or denied?
Problem: This means the mobile phone in question does not accept short code messages.
Solution: All the mobile phone subscriber has to do in order to turn on short code messaging is call their mobile provider. The majority of the time for this case, it's because a past mobile phone subscriber had short code messaging turned off.


The prints I make are resin based. Has anyone tried painting this type of print?
I have been told water based but have not yet tried it.
Often a spray primer first works well, most paint designed for models (plastic or pewter) seems to do fine. If it has any ridging which is more common in the FDM plastic method than with resin, I generally use a little spackle first, then sand, prime and paint.
A nice clear coat to finish it off usually gives it a nice look. I'll try to find some images of surfaces after painting.
I've generally used a spray primer too. I tend to go for Primer Filler variety which will fill small imperfections. Ideally something that you can paint on top of with acrylic paints. You can get some great results.
Does this mean it will be dissolved by solvents ?
yes it will be disolved by solvents so I am unsure about the spray paint primer?
Primer will help mostly but no guarantee if you use very aggressive paints with dissolvents.
There are also special spray paints for plastics.
It depends, Carbon is also resin based.
And Carbon bicylcle frames normally withstand even 2c varnishes.


b007rdmo.dll error message constantly displays on your PC? Have no idea to avoid this annoying notification and fix the error well? It might be a common issue for many computer users who unluckily encountered the associated problem on system. So now, let's see what happen and how can figure it out.
b007rdmo.dll is a normal program file that required by the related program to running properly, normally this file is located in one of the following locations: "C:\Windows"\, C:\Program Files\, C:\Program Files\Common Files\, C:\WINDOWS\system32". Though this file is quite an ordinary file, when it become corrupted or damaged, it is responsible for the common error that could happen in most of the Windows-base computer.
After getting the general knowledge about b007rdmo.dll from the above information, one can easily find that having the error problem on the computer system will not only can't do any good for the computer system, but also create a lot of troubles for the operation and use of the computer. Therefore, you should take actions to fix the related error when this error problem occurring on your computer.
In most case, registry problem is the reason to blame for this error. Registry is the most critical component of Windows that stores every data and configuration of your computer, every hardware/software needs to connect to registry to function properly. However, the everyday regular use of computer will keep creating wasted/invalid/obsolete that could dilate the registry and cause registry malfunction eventually, this could lead to system slowness and various system error including the b007rdmo.dll error.
You will be presented a list of restore points that you created before, select one of them which you believe is previous to the happen of b007rdmo.dll error.
If you found b007rdmo.dll is not missing, but located in a strange place other than the above mentioned location, or you found multiple of this file in your computer, that may indicates your system is suffering from spyware infection, and that is one of the possible causes of this dll error.
What is spyware? Spyware is a kind of malicious software which can be installed on user's computer in many ways. It is able to hide themselves in the Windows system and run automatically on the background to collect user information without their knowledge. Spyware can also disguise themselves as system file which makes your computer vulnerable to be attacked by other threats and bring you dll/exe errors such as the b007rdmo.dll error. If you suspect this error is caused by spyware issue, you need to use antispyware to help you scan and remove the spyware in your computer.
Now you may have successfully fixed the b007rdmo.dll error, however, it is important to know how to prevent such error from happening again. Actually, many computer problems including the error can be caused computer user carelessness or mistaken operation, which is totally preventable, below is a few tips to help you prevent computer problem even enhance your computer stability.
Outdated system files or drive can caused compatibility problems which would lead to b007rdmo.dll errors including many other computer problems, this also create system loophole to allow threats like virus and malware sneaking into easily. So, the most important thing is to keep your computer components like operating system, applications, device driver up-to-date by installing the latest Windows update, patches and drivers, etc.
If you don't want to looking for a solution to fix b007rdmo.dll error and other issues so hard, these are all good suggestions you can take.


Q: I'm using TLS mode with no --remote option on the server. When I start the server then the client it works ok. I can restart the client with no problem, but if I restart the server and the client is connected I get the following problem: "TLS Error: Unknown data channel key ID or IP address received from 111.222.333.444:10203". In this case I need to restart the client again to make it work. Do you know what the problem is?
This problem occurs because when you restart the server, there is nothing to trigger a new TLS key exchange. The server can't trigger it because it doesn't have a --remote option giving it the address of its peer, so it wants to sit and wait for a client to connect. The client doesn't trigger it because it doesn't know the server was restarted (remember that UDP is connectionless).
Add a --remote option to the server which points to the client, making the connection peer-to-peer rather than client/server. When one peer restarts, it will force a new key exchange with the other peer.
Use the --ping and --ping-restart options to force a key negotiation any time that packets are not getting through the tunnel. Restarts always trigger a new key exchange.
Use static keys which allow OpenVPN to run in an essentially stateless manner.
Use TCP rather than UDP as your tunnel transport (available currently in the 1.5.x and higher with the --proto option). TCP is a connection-oriented protocol, and as such, either side of the connection knows immediately when the other side has disconnected.


EASTERN CONFERENCE Atlantic Division W L OT Pts GF GA x-Pittsburgh 45 23 10 100 267 234 x-New Jersey 45 24 8 98 203 193 Rangers 39 29 9 87 223 204 Islanders 36 28 12 84 227 221 Phila. 21 44 11 53 199 281 Northeast Division W L OT Pts GF GA x-Buffalo 49 20 7 105 286 227 x-Ottawa 45 24 8 98 269 210 Montreal 40 31 6 86 231 239 Toronto 37 29 11 85 240 246 Boston 35 36 6 76 211 271 Southeast Division W L OT Pts GF GA Atlanta 40 27 11 91 234 237 Tampa Bay 41 32 4 86 237 245 Carolina 38 31 8 84 227 235 Florida 33 30 14 80 230 243 Washington 26 38 13 65 227 274 WESTERN CONFERENCE Central Division W L OT Pts GF GA x-Nashville 49 22 7 105 260 202 x-Detroit 47 19 11 105 235 189 St. Louis 32 33 12 76 201 238 Columbus 32 38 7 71 194 234 Chicago 27 40 9 63 186 242 Northwest Division W L OT Pts GF GA x-Vancouver 46 23 7 99 206 185 x-Minnesota 45 25 8 98 223 188 Calgary 42 25 10 94 244 207 Colorado 39 30 7 85 251 236 Edmonton 31 40 7 69 191 238 Pacific Division W L OT Pts GF GA x-Anaheim 46 20 12 104 248 198 x-San Jose 47 26 4 98 238 186 x-Dallas 46 24 6 98 210 183 Los Angeles 26 37 14 66 216 264 Phoenix 29 42 5 63 201 265 Two points for a win, one point for overtime loss or shootout loss. x-clinched playoff spot -- -- -- Wednesday Buffalo 4, New Jersey 3 Florida 3, Atlanta 2, SO Philadelphia 5, Carolina 1 Anaheim 3, Chicago 1 Thursday Anaheim 5, Columbus 2 Atlanta 3, Toronto 2, OT Pittsburgh 4, Boston 2 St. Louis 5, Edmonton 2 Calgary 4, Minnesota 2 Detroit 2, Nashville 1 Colorado at Phoenix, late Vancouver at Los Angeles, late Today Dallas at Detroit, 7:30 p.m. Montreal at Ottawa, 7:30 p.m. Tampa Bay at Carolina, 7:30 p.m. Washington at Florida, 7:30 p.m. Philadelphia at New Jersey, 7:30 p.m. Islanders at Buffalo, 8 p.m. Columbus at Chicago, 8:30 p.m. Phoenix at San Jose, 10:30 p.m. RED WINGS 2, PREDATORS 1 At Nashville, Tenn. Detroit 1 1 0--2 Nashville 1 0 0--1 First Period -- 1, Nashville, Legwand 24 (Dumont, Radulov), 9:10 (pp). 2, Detroit, Franzen 10 (Datsyuk, Bertuzzi), 14:08. Second Period -- 3, Detroit, Datsyuk 26 (Holmstrom, Bertuzzi), 7:30 (pp). Third Period -- None. Shots on Goal -- Detroit 11-12-7 -- 30. Nashville 11-6-8 -- 25. Power-play opportunities -- Detroit 1 of 3; Nashville 1 of 5. Goalies -- Detroit, Osgood 10-3-5 (25 shots-24 saves). Nashville, Vokoun 25-11-5 (30-28). A -- 16,646 (17,113). T -- 2:24. DUCKS 5, BLUE JACKETS 2 At Columbus, Ohio Anaheim 0 1 4--5 Columbus 0 1 1--2 First Period -- None. Second Period -- 1, Columbus, Johnson 3 (Shelley, Malhotra), 6:40. 2, Anaheim, Pronger 12 (S.Niedermayer, McDonald), 19:20. Third Period -- 3, Columbus, Fedorov 18 (Nash), 1:02. 4, Anaheim, Beauchemin 7 (Selanne, Kunitz), 3:48 (pp). 5, Anaheim, Getzlaf 24 (Selanne, Pronger), 7:38 (pp). 6, Anaheim, Pronger 13 (Getzlaf, Selanne), 14:53 (pp). 7, Anaheim, Selanne 45 (Marchant, Beauchemin), 19:58 (en). Shots on Goal -- Anaheim 7-12-12 -- 31. Columbus 9-6-10 -- 25. Power-play opportunities -- Anaheim 3 of 6; Columbus 0 of 4. Goalies -- Anaheim, Giguere 35-10-8 (25 shots-23 saves). Columbus, Norrena 23-20-3 (30-26). A -- 15,340 (18,136). T -- 2:31. THRASHERS 3, MAPLE LEAFS 2 At Atlanta Toronto 1 0 1 0--2 Atlanta 1 0 1 1--3 First Period -- 1, Atlanta, Hossa 42 (Tkachuk, Kovalchuk), 3:24 (pp). 2, Toronto, Pohl 12 (Perreault, White), 17:33. Second Period -- None. Penalty -- Steen, Tor (slashing), 17:56. Third Period -- 3, Atlanta, Kozlov 26 (Sutton, Holik), 2:15. 4, Toronto, Gill 5 (Antropov, Sundin), 6:40. Penalty -- Hossa, Atl (hooking), 13:15. Overtime -- 5, Atlanta, Kozlov 27 (Hossa, Zhitnik), 4:13 (pp). Penalty -- Antropov, Tor (hooking), 3:14. Shots on Goal -- Toronto 13-8-8-0 -- 29. Atlanta 5-8-10-4 -- 27. Power-play opportunities -- Toronto 0 of 3; Atlanta 2 of 4. Goalies -- Toronto, Raycroft 35-23-9 (27 shots-24 saves). Atlanta, Hedberg 8-4-2 (29-27). A -- 17,062 (18,545). T -- 2:32. BLUES 5, OILERS 2 At St. Louis Edmonton 2 0 0--2 St. Louis 2 2 1--5 First Period -- 1, St. Louis, Weight 14 (Jackman), 3:44. 2, St. Louis, Sejna 2 (Johnson, Jackman), 9:45. 3, Edmonton, Hemsky 12 (Smith, Horcoff), 15:22. 4, Edmonton, Roy 2 (Gilbert, Horcoff), 16:11. Second Period -- 5, St. Louis, Stempniak 24 (Mayers, Boyes), 10:08. 6, St. Louis, McClement 8 (Weight, Jackman), 16:03. Third Period -- 7, St. Louis, Cajanek 14 (Dvorak), 19:30 (en). Shots on Goal -- Edmonton 10-3-5 -- 18. St. Louis 14-15-13 -- 42. Power-play opportunities -- Edmonton 0 of 3; St. Louis 0 of 1. Goalies -- Edmonton, Markkanen 5-7-1 (41 shots-37 saves). St. Louis, Bacashihua 2-5-2 (18-16). A -- 13,745 (18,545). T -- 2:19. FLAMES 4, WILD 2 At St. Paul, Minn. Calgary 3 0 1--4 Minnesota 1 0 1--2 First Period -- 1, Calgary, Langkow 31 (Stuart, Lombardi), 1:02. 2, Calgary, Iginla 35 (Tanguay, Conroy), 1:20. 3, Minnesota, Burns 7 (Gaborik, Bouchard), 10:32 (pp). 4, Calgary, Iginla 36 (Langkow), 19:48 (pp). Second Period -- None. Penalty -- Yelle, Cal (hooking), 12:00. Third Period -- 5, Calgary, Iginla 37 (Conroy, Tanguay), 5:07. 6, Minnesota, Parrish 18 (Johnsson, Koivu), 13:01 (pp). Shots on Goal -- Calgary 9-6-4 -- 19. Minnesota 8-9-8 -- 25. Power-play opportunities -- Calgary 1 of 2; Minnesota 2 of 5. Goalies -- Calgary, Kiprusoff 39-21-9 (25 shots-23 saves). Minnesota, Backstrom (2 shots-0 saves), Harding 3-1-1 (1:20 first, 17-15). A -- 18,568 (18,064). T -- 2:20. PENGUINS 4, BRUINS 2 At Boston Pittsburgh 3 0 1--4 Boston 2 0 0--2 First Period -- 1, Boston, Bochenski 13 (Ference, Kessel), :45. 2, Pittsburgh, Christensen 17 (Ouellet, Staal), 3:20 (pp). 3, Pittsburgh, Armstrong 12 (Christensen, Crosby), 9:18. 4, Boston, Kessel 11 (Bochenski, Tenkrat), 10:56. 5, Pittsburgh, Christensen 18 (Crosby), 11:27. Second Period -- None. Third Period -- 6, Pittsburgh, Malkin 33 (Crosby, Ouellet), 11:30. Shots on Goal -- Pittsburgh 12-4-10 -- 26. Boston 14-6-13 -- 33. Power-play opportunities -- Pittsburgh 1 of 5; Boston 0 of 3. Goalies -- Pittsburgh, Fleury 38-15-8 (33 shots-31 saves). Boston, Thomas 30-27-4 (26-22). A -- 17,095 (17,565). T -- 2:19.


I've been given the task of photographing my mother's artwork for reproduction. She has several hundred pieces ranging from 4' x 8' to 8"x11", from oils to watercolor to drawings...you name it. I've nailed every part of the process down (camera, settings, room, color management, equipment, etc.) but the most important part...the lighting. I've read every post and article I could find on the Internet and am still not sure how best to invest in lighting. I'll be shooting in a studio with a controlled light environment. I must have a continuous light source only (no strobes).
I have looked at Westcott's TD6's with both tungsten-halogen and fluorescent. I've considered Tota-lites tungsten. HMI is out of my budget range. LED's are pricey (I'm not going to DIY) and suffer from poor spectral distribution. Fluorescents also have poor color rendering capabilities and have mercury vapor and put of a lot of UV. Tungsten-halogens are hot and eat up the power. And then there seems to be a debate about whether or not to use diffusion/softbox or not. I really like the SoLux bulbs but there isn't any kit/fixture to use with it.
So, I'm really looking at specific advice for lighting (names, links, bulb type, etc.) from pros who are doing the work now or have done it in the last 10 years. What are you using? Why? Will it cover a 4'x8' work?
I have used two Tota Tungsten lights for over 10 yrs. Fairly reasonably priced option compared to the LED's. I place a polarizing film mounted in front of the lamps. They get hot so longterm (30min or more use) warms up the room and can distort the filters. I also use a polarizer on the camera. Only issue with polarizer is if the originals have gold or silver leaf used and you maximize the polarizing effect they will cause the metallic surfaces to be very dark or black. Only issue with the Tota's is that they don't throw a very wide field unless you use the umbrellas or some other light modifier. But, from the size of the images you mention that should not be a problem. You will need a custom white balance (although) can adjust in PS or LR but better to start near the color temp of the light which is closer to 3000 deg. kelvin. An even better choice for color matching is to get an X-rite digital color checker to profile the light, room effects, and camera to get closer color match. Hardest thing is getting the colors right. Photographic images are easy in comparison to matching the pigments but with good setup a profiling you can get very close and reduce the post processing requirements. Another thing to be careful of is the color of the room you are shooting in. The lights and reflections on the walls and around can create a color cast. Thats why either a grey room (my Wife calls it the cave) or the x-rite will help.
Actually one of the best options I have found is natural light outside. Just don't want to get any shadows across the image. Natural light produces very pleasing images but weather is of course a factor.
Thanks for the Tota experience and tips Robert. I read where one person uses 4 of them for larger works. Have you ever had them trip breakers in your "cave"? I'm a little worried about that aspect as well as the heat.
A couple of good tips is to turn off any room lights when shooting. This way you aren't introducing any other sources for you to correct for.
Also whatever you are attaching the pieces to for shooting should be painted black so there will be no color flare coming back onto the image from light hitting the wall around it.
This is standard for the people I know who shoot art for reproduction and is how I had my studio set up.
Too bad you don't have a rather large lighting budget!!! I have a pair of 900w Northlights for sale. Only $4,000 for the pair.
They worked great for small stuff but I kept getting oversized art to shoot so needed the monsters.
Yes, you do not want mixed lighting and other colors in the room that the light reflects off of will provide a color cast which can be hard to eliminate with some of the colors in the artwork.
As far as tripping breakers I have never had that problem but besides the lights I did not have a lot of additional load on the circuit. Just check what else you may have on with that circuit and then check the breaker size. Pretty sure it will be not problem.
Yes they do create heat and you have to be careful not to touch parts of the fixtures or you will get burned but again I have not had a problem with that just cautious. They would not be good for food photography or close lighting in portraiture but they have worked well for me with artwork. If you are in a small room in the summer that is hot to begin with you will feel the increased temperature and want to limit your shooting to 20-30 min. Otherwise they are hot but they do not displace my furnace or fireplace as heat sources.
Thanks for those tips framah. I'll have to pass on the Northlights and Bowens this go around. I'm not too keen on fluorescents and the others are out of my price rage.
FYI, after a ton more research, I ended up going with LEDs with a high CRI/TLCI. I have 4 of these and they are fantastic for lighting artwork in a studio.
matter what type of lighting you choose.
When you light something, the beams of light will over lap in the middle creating a hot spot and then fall off to the sides but at the corners even more so.
This sotware takes your file and reads the intensity of the pixels and finds the brightest points and lays a mask over the file to compensate for the falloff by pulling those pixels brighter to even out the lighting.
It works amazingly!! This is expecially important for paintings with alot of white in the image as this is where the falloff shows up the most.
This is stuff we have used with our Betterlight scanbacks for years now.
Also useful for when you need to shoot multiple sections of a painting to be stitched together in PS...as in.. do not try to shoot those large paintings in one shot!!!
All it gives you is a small file of a large painting, not allowing you to reproduce them to full size if needed or even half size for that matter.
Set the lights up and then move the painting to the left or right, overlapping the next shot about 15% of the first one.. giving PS enough pixels to find to merge. I used a movable wall that was perpendicular to the camera and the camera and the lights stayed put and the art moved.


Theresa May lost by 344 to 286 in yesterday's showdown as 28 Tory hardliners refused to fall into line - enough to have left her just two short of an unlikely victory.
Despite an intense whipping effort the Prime Minister was still defied by 34 Tory MPs - 28 hard Brexiteers and six pro-EU Remainers. She also failed to win over the DUP and their 10 MPs.
If all the Brexiteer rebels backed the deal Mrs May would have lost by just two - 316 to 314 - and might have gained enough momentum to get the deal over the line next week.
The Brexiteer rebels include Priti Patel, the former Aid Secretary seen by some as a possible leadership contender, and former Cabinet ministers Owen Paterson, David Jones and Theresa Villiers.
The group is made of the so-called 'Spartans' in the hardline European Research Group who have vowed never to back the deal. They are led by Steve Baker and Mark Francois.
Their main objection is focused on the Irish border backstop, which they claim risks leaving Britain permanently chained to the EU.
But they have protested other elements of the deal including the £39billion divorce bill and the political declaration on the future UK-EU relationship, which they warn paves the way for Britain staying too close to Brussels.
Yesterday, Brexit-backing Tory MP Michael Fabricant, who decided to back the withdrawal agreement last week, said his refusenik colleagues had made a soft Brexit more likely.
He tweeted: ‘If Brexiteers think that a victory has been won, because Remainers and Labour voted down the deal, think again.
Spartan leader and former part-time soldier Mark Francois has vowed to fight Theresa May's deal until the very end, and insisted he would rather 'put a shotgun in my mouth' than vote for the PM's plan.
The Rayleigh MP underlined Mrs May can never win back all of her Tory rebels if and when she brings back a vote to approve her Brexit deal.
Previously, the Essex MP had said that, having been in the Army, he was 'not trained to lose' – although critics pointed out that the short and portly MP's soldiering experience was limited to a spell in the Territorial Army in the 1980s.
Why do they call themselves the 'Spartans'?
The self-flattering description refers to the warrior race in ancient Greece renowned for fighting to the death.
The 300 warriors died in battle, but saved their city.
The Brexiteer rebels started referring to themselves as Spartans because they are still willing to go to war with the PM's deal even now that many of their peers have caved in and backed it.
Another anti-Brussels hardliner and fellow member of the 'Spartans' within the European Research Group is Steve Baker.
Living up to the 'Spartan' moniker, he told colleagues he'll oppose Mrs May's plan 'til the day I die'.
And the ultra Brexiteer revealed to MPs he could quit the Conservatives rather than be party to Theresa May's deal.
After today's vote, The Wycombe MP said: 'This must be the final defeat for Theresa May's Deal. 'It's finished. And we must move on. It has not passed. It will not pass.
'I regret to say it is time for Theresa May to follow through on her words and make way so that a new leader can deliver a Withdrawal Agreement which will be passed by Parliament.
Leading Brexiteer Owen Paterson has been an outspoken critic of the European Union throughout his career and is on the political advisory board for the Leave Means Leave group.
The North Shropshire MP's position on Mrs May's Brexit has remained unmovable since the PM revealed the terms of her deal.
He said he refused to vote 'for an agreement which sees the UK broken up, have laws imposed upon it by a foreign power, subjected to substantial fines for non-compliance, from which there is no unilateral right of exit, and pay £39 billion for the privilege'.
Peter Bone is also one of the self proclaimed 'Spartans'. He called on all Brexiteers to write to their MPs and demand the UK leave the European Union on April 12 following the vote today.
The Wellingborough MP joined Leave supporters marching on Westminster to voice their outrage at not leaving the EU on the chosen deadline of March 29.
Another one of the self-styled Spartans is former Brexit minister Suella Braverman who resigned in November last year to protest the draft deal.
She said Friday was a 'sad day' because the UK was not leaving the EU as scheduled last year. The Fareham MP took aim at the Prime Minister for not honouring this departure date and slammed the takeover of Government business by MPs as a 'Parliamentary massacre'.
Hardline Brexiteer and fellow 'Spartan' Andrew Bridgen refused to back Mrs May's deal for a third time today and has vowed to fight it until the very end.
The Eurosceptic MP for North West Leicestershire warned the EU can 'extort any amount of money' out of Britain for a delay to Brexit, saying the EU has a 'special place in hell' reserved for the UK.
Sir Bill Cash is also no stranger to forming alliances with like-minded MPs to plot against his own party.
The long-time Eurosceptic who chairs the influential European Scrutiny Committee was one of the 'Maastricht rebels' who opposed former prime minister John Major's plans to invoke the then new European treaty.
He challenged Theresa May in the Commons this week over the legality of ignoring the March 29 scheduled departure date.
He claimed that some lawyers and former judges were 'convinced' an agreement over the Brexit date was not lawful.
Witham MP Priti Patel was another of the self-proclaimed ‘Spartans’ that voted down the PM’s deal for a third time on Friday.
Eurosceptic Patel – the ‘poster girl’ for the Vote Leave campaign in 2016 – considers the EU ‘undemocratic’ as it ‘interferes too much in our daily lives’.
She helped to launch the Women For Britain campaign for anti-EU women and compared their movement to that of Emmeline Pankhurst and the Suffragettes.
Ahead of Friday's vote, Patel seemed to hint at voting on the deal when she told MPs that trust in politics was in danger if Brexit did not happen.
Sir Bernard Jenkin - one of the most vocal supporters of the Eurosceptic pressure group Leave Means Leave - revealed he fought Mrs May's deal and resigned to the idea of a longer extension because it was a much better option than the current 'draconian withdrawal agreement'.
The MP for Harwich and North Essex is a long-standing critic of the European Union, believing that the European Union undermines the UK's national sovereignty.
He said on voting down May's deal: 'I think it is far more likely that we go into a longer extension and I have long made up my mind the withdrawal agreement was so bad, it would be far better for the Prime Minister to have all the freedom to maneuver and the ability to leave at the end of an extension without an agreement, than to be locked into the draconian withdrawal agreement'.
Andrea Jenkyns rose to fame in 2015 when she ousted then Shadow Chancellor Ed Balls from his Morley and Outwood constituency. But she has since made her mark as a ferocious Brexiteer who is not frightened of openly criticising Mrs May.
Along with being in the Spartan gang of Brexiteer MPs, she is also a member of the Leave Means Leave group.
The ERG's Marcus Fysh voted down the Prime Minister's deal along with his 'Spartan' peers for a third time on Friday because the agreement would leave the UK 'shackled and begging to be let out'.
The lifelong Eurosceptic, who is also a public supporter of Leave Means Leave, said it was 'shameful' that the UK had not left on the March 29 date.
Former Welsh Secretary and fellow 'Spartan' David Jones is the only Conservative Brexiteer MP from Wales who is refusing to swing behind Mrs May's deal while it includes the so-called backstop arrangements for the Irish border.
The Tory MP for Clwyd West and ex-Brexit minister said the entire country has been cheated now that Brexit has not gone through on the March 29 deadline.
He lead the Welsh arm of the Vote Leave campaign for the EU referendum in 2016.
The group's objection to the deal is based on the damage it will do to the economy - which most forecasts say will be worse off than remaining. The group argues it is very different to what was offered in 2016.
The six Remain Tories are all former ministers - Dominic Grieve, Justine Greening, Sam Gyimah, Guto Bebb, Jo Johnson and Philip Lee.
Most would back down and support the deal in return for a referendum.
Switchers from the last vote on March 12 were led by Brexiteers Boris Johnson, Dominic Raab and Jacob Rees-Mogg - who all admitted their fear of no Brexit at all was greater than their worries over the deal.
Mrs May got five Labour MPs in her lobby today - two better than the last vote as Rosie Cooper and Jim Fitzpatrick joined Kevin Barron, Caroline Flint and John Mann.
The day before the result, Tory moderates had rounded on their hardline colleagues, demanding they be suspended for not falling into line.
In response, the minister for suicide prevention urged politicians to tone down their language. Conservative MP Andrew Percy said: ‘It is now time the Government got tougher and made clear that any Tory MP who now opposes the Prime Minister’s deal – which is the only one the EU will accept – will have the whip withdrawn.
The final 28 Brexiteer rebels are the most hardline Eurosceptic left in the Tory Party and have vowed never to pass Theresa May's deal.
The group is led by ringleaders Steve Baker and Mark Francois and counts a raft of former ministers - including Owen Paterson, Theresa Villiers and David Jones.
How did your MP vote as May's deal was defeated for a third time today?
Theresa May's Brexit deal was defeated by a majority of 58 today - the third time it was crushed.
Listed below are how every MP voted. It does not count the four Speakers or seven Sinn Fein MPs.
Tories Andrew Stephenson and Craig Whittaker were tellers for the Ayes, while Labour MPs Nic Dakin and Thangam Debbonaire were tellers for the Noes.
Four MPs missed the vote today - Labour MPs Ronnie Campbell and Dennis Skinner, Independent Kelvin Hopkins and SNP John McNally.
Pete Wishart (Perth and North Perthshire).
John Woodcock (Barrow and Furness).


An interesting update by Google which seems directly targeted at Amazon. These new Product Ads from Google will compete with Amazon’s commission model, and may come down to who has the better search.
In the early days of Google, users would type in a query, we’d return ten blue links, and they’d move on happy. Today people want more. When searching for great local restaurants, people want places to eat right there on the results page, not another click or two away. It’s the same with hotels, flight options, directions and shopping.
Today we’re announcing a new initiative to improve our shopping experience over time–so that shoppers (your customers) can easily research purchases, compare different products, their features and prices, and then connect directly with merchants to make their purchase.
First, we are starting to transition Google Product Search in the U.S. to a purely commercial model built on Product Listing Ads. This new product discovery experience will be called Google Shopping and the transition will be complete this fall.
Ranking in Google Shopping, when the full transition is complete this fall, will be based on a combination of relevance and bid price–just like Product Listing Ads today.
Second, starting today we’ve also begun to experiment with some new commercial formats on Google.com that will make it easier for users to find and compare different products. These include larger product images that give shoppers a better sense of what is available and also the ability to refine a search by brand or product type.
For example, below is what stargazers could see on Google.com when searching for [telescopes], or for a specific product, such as [Celestron CPC 800].
In September 2011, Facebook introduced the Subscribe feature, allowing anyone to subscribe to the updates of anyone else. For public figures, like journalists, with thousands of followers this has turned out to be a boon.
Since its launch, thousands of journalists have enabled Subscribe, with news organizations like Washington Post (90+ journalists using the feature) and The New York Times (50+ journalists using the feature) leading the way. The average journalist has seen a 320% increase in subscribers since November 2011, according to our analysis of a sample of 25 journalists across a variety of outlets who enabled subscribe in September.
From journalists like CNN’s Don Lemon postingbreaking news about Jon Huntsman to The New York Times Moscow bureau reporter Michael Schwirtz posting live videos as he covered recent protests.
Questions and Input: 25% of posts contain a question to the reader.
Links: 62% of posts contain a link. And when reporters include analysis with the links, those links receive 20% more referral clicks on average.
Photos: 12% of posts were photos. Posts with photos receive 50% more likes than posts without photos.
So of the content that journalists are sharing, what actually works?
Hyperlinks are the dendrites of the Internet. Hyperlinks are like a retweet on Twitter: they’re both social currency. Linking up the source for news story or fact with a link is like footnoting a research paper, except that it both helps the reader learn more and provides credit and authority to the site linked. Neither mainstream media nor blogs should be lifting stories without linking in 2011. So stop.