Subset (2)

T1_diagnosis · 300 rows

Split (1)

train · 300 rows

index int64	image string	context string	question string	answer string	answer_aliases string	image findings string	ORPHA_code string	primary_modality string	pmcid string
2	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAGYA2YDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is a 72-year-old man. ### Symptoms and Signs - The patient presented with long standing right sided hearing loss and tinnitus. - He denied otorrhea, headache, or facial nerve palsy. - Examination, including facial nerve function and otoscopy, was unremarkable. ### Medical Histor...	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	1. Bilateral facial canal meningoceles (fallopian canal meningoceles)	bilateral facial canal meningoceles,fallopian canal meningocele,fallopian canal meningoceles,bilateral facial nerve meningoceles,bilateral facial canal meningocele,facial canal meningoceles involving the tympanic segment,bilateral fallopian canal meningoceles	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- High resolution noncontrast CT demonstrated abnormal fluid or soft tissue density filling the geniculate ganglia and the tympanic segment of the facial canal with evidence of impingement on the middle ear ossicles on the right side.\n- ...	ORPHA:238624	mri	PMC10331308
3	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCADmAVwDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is a 47-year-old woman. ### Clinical Course - The patient underwent double lung transplantation. - Postoperatively, she developed a persistent eruption.	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	Acute graft versus host disease	Acute graft-versus-host disease,acute graft versus host disease	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- On postoperative day 99, confusion developed, and brain MRI confirmed posterior reversible encephalopathy syndrome.", "markdown": "### Imaging Findings\n- On postoperative day 99, confusion developed, and brain MRI confirmed posterior r...	ORPHA:99920	pathology_micro	PMC8193367
7	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAFyA6IDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is a 3-year-old girl. ### Symptoms and Signs - The patient presented with serosanguineous purulent discharge from her right ear. - During surgery the external auditory canal and mastoid were full of polypoid granulomatous tissue while the tympanic membrane was intact without perf...	Based on the patient's brief clinical history and the provided temporal-bone CT and pathology images, what diagnoses should be considered for this patient?	Embryonal rhabdomyosarcoma of the mastoid and middle ear	["Embryonal rhabdomyosarcoma of the mastoid and middle ear", "Embryonic rhabdomyosarcoma of the mastoid and middle ear", "Temporal bone embryonal rhabdomyosarcoma", "Middle ear embryonal rhabdomyosarcoma", "Mastoid embryonal rhabdomyosarcoma"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- CT scan showed soft tissue density in the mastoid and middle ear.\n- The mass involved the external ear and projected from the external auditory meatus, with ragged erosion in mastoid air cells and external surface of mastoid bone.", "m...	ORPHA:99757	pathology_micro	PMC3420705
10	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAJeAjwDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is a 34-year-old male. ### Symptoms and Signs - The patient presented with jaundice for 20 days. ### Medical History - The patient has no relevant medical history. ### Laboratory Results - Total bilirubin on admission was 5.17 mg/dl. - Direct bilirubin on admission was 2.49 mg/...	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	Inflammatory myofibroblastic tumour of the common bile duct	["Inflammatory myofibroblastic tumor of the common bile duct", "Inflammatory myofibroblastic tumour of the common bile duct", "Common bile duct inflammatory myofibroblastic tumour", "Common bile duct inflammatory myofibroblastic tumor", "Biliary inflammatory myofibroblastic tumour", "Biliary inflammatory myofibroblasti...	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- CT revealed soft tissue nodules in the common bile duct with clear borders, inhomogeneous morphology, heterogeneous density, and nodules bulging into the lumen, showing significant heterogeneous enhancement in the venous phase with grad...	ORPHA:178342	pathology_micro	PMC9976409
12	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAJQAVgDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is a 28-year-old woman. - The patient is African American. ### Symptoms and Signs - The patient had a 2-month history of polyarthralgia, headaches, recurrent fevers, tachycardia, and pruritic dermatitis. - The patient’s polyarthralgia involved her wrists, ankles, and knees asymme...	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	Adult-onset Still disease	["Adult-onset Still's disease", "adult onset still disease"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- Chest X-ray and abdominal ultrasound were unremarkable.\n- Pelvic and lumbar spine X-rays showed mild sclerotic changes of the bilateral sacroiliac joints and lower lumbar spine.", "markdown": "### Imaging Findings\n- Chest X-ray and ab...	ORPHA:829	clinical_exam	PMC10363657
15	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAGUA74DASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is 35 years old. - The patient is female. ### Symptoms and Signs - The patient had progressive difficulty maintaining balance over 2 months. - The patient reported dull, constant global headaches for 2 months. - The patient had two episodes of generalized tonic-clonic seizures wi...	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	1. Primary central nervous system lymphoma	["1. Primary central nervous system lymphoma", "1. primary CNS lymphoma", "1. PCNSL", "Primary central nervous system lymphoma", "primary CNS lymphoma", "PCNSL"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- CT scans of the chest and abdomen showed no abnormalities.\n- Brain MRI revealed multiple bilateral cortical and subcortical masses deep in the periventricular region that were T1-hypointense, T2-heterogeneously hyperintense, and exhibi...	ORPHA:46135	mri	PMC11363720
20	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAIaAgoDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is a 24-year-old Caucasian woman. ### Symptoms and Signs - Seizures began at age 11 and later became complex partial seizures, sometimes secondarily generalized. - Seizures occurred daily despite multiple antiseizure medications. - She developed cognitive and behavioral decline a...	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	Dysembryoplastic neuroepithelial tumor	["DNT", "dysembryoplastic neuroepithelial tumour", "Dysembryoplastic neuroepithelial tumor (DNT)"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- Magnetic resonance imaging showed a cortico-subcortical parietal tumor with all the characteristics of these types of tumors.\n- Initial CT scan showed a left temporoparietal diffuse hypodense area, quite inhomogeneous without mass effe...	ORPHA:251946	mri	PMC3183037
21	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAFwAXADASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - A 30-year-old Caucasian man. ### Symptoms and Signs - Persistent right ankle pain for months after an ankle sprain despite immobilization in a plaster cast and physical therapy. - Tenderness at the ventral aspect of the ankle next to the medial malleolus. - Dorsiflexion of the ankle was pain...	Based on the clinical information and all provided medical images, what diagnoses should be considered for this patient?	Localized tenosynovial giant cell tumor of the tendon sheath	["localized tenosynovial giant cell tumor of the tendon sheath", "tenosynovial giant cell tumor of the tendon sheath", "giant cell tumor of tendon sheath", "localized giant cell tumor of tendon sheath", "localized tenosynovial giant cell tumor", "localized TGCT", "tenosynovial giant cell tumor", "pigmented villonodular...	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- In the first patient, an initial X-ray of the right ankle showed no pathological findings.\n- In the first patient, ultrasound showed a solid, homogeneous hypoechoic mass measuring 3.5 × 2.5 × 2 cm near the right ankle.\n- In the first ...	ORPHA:66627	mri	PMC2803852
23	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAE8AbgDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is an 80-year-old female. ### Symptoms and Signs - She presented with rapidly worsening lethargy and altered mental status. - Examination noted a painful left lower extremity without crepitus or bullae. ### Medical History - Diabetes. - Hypertension. ### Laboratory Results - Wh...	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	Necrotizing fasciitis	["necrotising fasciitis"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- Left lower leg X-rays showed mild soft tissue edema, but no gas in tissue planes.\n- Point-of-care ultrasound showed thickened subcutaneous tissue with fluid accumulating superficial to the deep fascial layer greater than 4 mm in the su...	ORPHA:699697	ultrasound	PMC7176767
26	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAHSAdQDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is a 35-year-old male. - He was previously healthy. ### Symptoms and Signs - He presented with intermittent fever and myalgia for one month. - He had painful swelling of the left upper arm, without overlying skin lesions. ### Workup Summary - Microbiological studies and serology...	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	Acute febrile neutrophilic myositis associated with acute myeloid leukemia	["paraneoplastic neutrophilic myositis associated with acute myeloid leukemia", "acute febrile neutrophilic myositis associated with acute myeloid leukemia", "neutrophilic myositis as the first manifestation of acute myeloid leukemia"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- Ultrasonography showed diffusely increased echogenicity in thickened triceps, brachialis and gluteus muscles.\n- MRI of the arm demonstrated diffuse homogenous signal intensity in the triceps and brachialis muscles.", "markdown": "### I...	ORPHA:519	pathology_micro	PMC3891084
27	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCADiAegDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is a newborn infant. ### Symptoms and Signs - Since birth, the infant had an oral lesion with feeding difficulty. ### Medical History - Maternal and fetal histories were noncontributory with a normal course of gestation and vaginal delivery at 37 weeks. - There was no relevant f...	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	Congenital epulis	["congenital epulis", "congenital granular cell tumor", "congenital granular cell epulis", "CGCT", "CGCE"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- Point-of-care ultrasonography showed a well-defined hypoechoic oval-shaped cystic lesion arising from the left upper gingiva, measuring about 1.17 cm × 1.33 cm.\n- On ultrasonography, there was no internal vascularity, signs of infectio...	ORPHA:157826	pathology_micro	PMC9638596
29	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAH0AfgDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - 22-year-old woman. ### Symptoms and Signs - Three weeks of mood swings, anxiety, depression, and progressively slow body movement. - On the day of admission, she was agitated and attempted suicide. - On presentation, she had altered mental status, acute psychosis with suicidal ideation, decr...	Based on the patient's brief clinical history and the provided pelvic MRI and ovarian pathology images, what diagnoses should be considered for this patient?	Anti-NMDA receptor encephalitis associated with ovarian mature cystic teratoma	["Anti-NMDAR encephalitis associated with ovarian mature cystic teratoma", "Anti-NMDA receptor encephalitis associated with ovarian teratoma", "Ovarian mature cystic teratoma with anti-NMDA receptor encephalitis", "Paraneoplastic anti-NMDA receptor encephalitis due to ovarian teratoma", "Anti-N-methyl-D-aspartate recep...	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- Initial brain imaging did not show acute intracranial abnormalities.\n- Pelvic MRI revealed bilateral ovarian cysts measuring 1.7 cm on the right ovary and 6.4 cm on the left ovary, appearing more consistent with a dermoid cyst or hemor...	ORPHA:217253	pathology_micro	PMC5953185
30	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCADoAVgDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is an 11.5-year-old female. ### Brief Clinical History - She was referred for evaluation of longstanding craniofacial and dental abnormalities. - She had a history of congenital skeletal abnormalities and developmental concerns reported in childhood.	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	Melnick-Needles syndrome	["Melnick-Needles osseous dysplasia", "MNS"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- Panoramic radiograph demonstrated absence of two right second tooth germs of the second molars (upper and lower), the right second lower premolar, and all third molars.\n- In place of the right lower second premolar there was a persiste...	ORPHA:2484	clinical_photo	PMC6252208
31	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAFwAfwDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is a 25-year-old woman. ### Symptoms and Signs - The patient had a one-month history of pain and swelling involving the proximal phalanx of the third finger of the left hand, with limited finger motion. - She reported no history of trauma. ### Medical History - No major prior co...	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	Giant cell tumor of bone of the proximal phalanx of the third finger	["giant cell tumor of bone of the proximal phalanx of the third finger", "giant cell tumor of the proximal phalanx of the third finger", "giant cell tumor of bone involving the proximal phalanx of the third finger", "giant cell tumor of bone in the hand proximal phalanx"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- The initial x-ray in May 2007 showed hypertransparency with increased bone volume in the proximal phalanx of the third finger.\n- After one month, the lesion on x-ray showed significant growth.\n- MRI in July 2007 showed a large expansi...	ORPHA:363976	xray	PMC4799160
32	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAGWAeQDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is a 10-year-old boy. ### Symptoms and Signs - The patient presented with fever and a painful hip. ### Medical History - The child did not have any chronic disease or predisposing factors. ### Laboratory Results - Laboratory tests revealed a total leukocyte count of 14,100/mm3 ...	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient? Use the imaging to localize the abnormality.	Pyomyositis of the tensor fascia lata	["pyomyositis of the tensor fascia lata", "tensor fascia lata pyomyositis"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- No abnormal view was seen in the pelvis roentgenogram.\n- Magnetic resonance imaging revealed fluid accumulation in the tensor fascia lata.\n- Control MRI of the left hip showed a significant decrease in the extent of involvement.", "ma...	ORPHA:764	mri	PMC2495003
36	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAFCAmoDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is a 52-year-old female. ### Symptoms and Signs - The patient initially presented with exercise-dependent muscle weakness, diplopia, and dysphagia. - During hospitalization, she developed respiratory failure followed by progressive multiorgan dysfunction with delirium, hepatitis,...	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	Hemophagocytic lymphohistiocytosis	["adult hemophagocytic lymphohistiocytosis", "HLH", "hemophagocytic syndrome", "macrophage activation syndrome", "MAS"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging a medical condition", "body": "- Magnetic resonance imaging of the brain revealed contrast-enhancing lesions compatible with central nervous system affection of systemic lupus erythematosus.\n- Whole-body positron emission tomography showed no evidence of ma...	ORPHA:158032	laboratory	PMC4736532
37	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAFoAWoDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is 28 years old. - The patient is male. ### Symptoms and Signs - The patient had epigastric abdominal pain for a year. - He developed early postprandial vomiting. - He had progressive weight loss. ### Medical History - No notable past medical history. - No fever was reported. #...	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	Eosinophilic enteritis	["eosinophilic enteritis", "eosinophilic jejunitis"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- Urgent esophagogastroduodenoscopy revealed significant gastric stasis hindering the examination.\n- After gastric emptying, endoscopic examination showed a slightly congestive appearance of the antro-fundic mucosa.\n- Esophagogastric-du...	ORPHA:2070	pathology_micro	PMC10948736
38	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAFWAbgDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is a 21-year-old man. - The patient had mild obesity with a body mass index of 28.2 kg/m2. ### Symptoms and Signs - Two weeks before admission, he was bitten by ants highly suspected to be fire ants. - Immediately after the bites, flare and wheal developed over the left arm, foll...	Based on the provided peripheral blood smear and renal biopsy images together with the brief clinical history, what diagnoses should be considered for this patient?	Hemolytic uremic syndrome	["Haemolytic-uremic syndrome", "Hemolytic Uremic Syndrome", "HUS", "Uremic Hemolytic Syndrome", "Hemolytic-Uremic Syndrome", "Haemolytic Uraemic Syndrome", "HUS (Haemolytic Uremic Syndrome)", "HUS (Hemolytic Uremic Syndrome)"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- Renal ultrasound showed increased echogenicity (grade I) in both kidneys with right renal size 12.4×5.45 cm and left renal size 12.5×5.4 cm.", "markdown": "### Imaging Findings\n- Renal ultrasound showed increased echogenicity (grade I)...	ORPHA:544458	pathology_micro	PMC3890644
40	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAGcAbgDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is a 48-year-old African-American man. - He lost 11 kg over 9 months before presentation. ### Symptoms and Signs - He presented with a slow-growing left neck mass. - He reported left arm pain and weakness, hoarseness, and intermittent fever with chills, without dyspnea, shortness...	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	High-grade myxofibrosarcoma	["Myxofibrosarcoma", "MFS", "High-grade myxofibrosarcoma", "High grade myxofibrosarcoma", "High-grade MFS", "High grade MFS", "Fibromyxosarcoma", "High-grade fibromyxosarcoma", "High grade fibromyxosarcoma"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- Ultrasound of the neck showed an ill-defined heterogeneous mass lateral to the left thyroid lobe resulting in mild mass effect.\n- Chest X-ray exhibited a mass extending from the hilum of the left lung with gross deviation of the trache...	ORPHA:79105	ct	PMC5339984
41	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAFGATwDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is an 8-month-old child. - The patient weighs approximately 8 kg. ### Symptoms and Signs - Clinical history was 15 days of abdominal pain with constipation and deterioration in general condition. - Abdominal examination revealed a left lumbar mass. ### Medical History - The pati...	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	Metanephric stromal tumor	["Metanephric stromal tumor", "Stromal metanephric tumor", "Metanephric stromal tumour", "Stromal metanephric tumour", "Metanephric stromal tumor of the kidney", "Metanephric stromal tumour of the kidney"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- Abdominal ultrasonography revealed a mass with two components, a predominant echogenic tissue component with central and peripheral anechogenic cystic zones forming a shoulder sign with adjacent healthy renal parenchyma.\n- CT scan reve...	ORPHA:2665	ct	PMC11046045
43	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAFUAwoDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is a 66-year-old Chinese man. ### Symptoms and Clinical Course - He had a 2-month history of recurrent fever and chills. - He later developed persistent fatigue, loss of appetite, malaise, and a 15 kg weight loss. - Symptoms did not improve significantly after initial antibiotic ...	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	Idiopathic multicentric Castleman disease, plasma cell type	["idiopathic multicentric Castleman disease", "iMCD", "idiopathic multicentric Castleman disease, plasma cell type", "plasma cell type idiopathic multicentric Castleman disease", "plasma cell variant idiopathic multicentric Castleman disease", "HHV-8-negative idiopathic multicentric Castleman disease", "multicentric Ca...	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- The patient’s initial chest CT scan revealed bilateral pneumonia with mild interstitial pulmonary edema and bilateral pleural effusion.\n- Subsequent chest CT scans showed obvious improvement of pulmonary abnormalities, with absorption ...	ORPHA:570431	pathology_micro	PMC10981217
44	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAFYArwDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is a term male infant with fetal ascites and abdominal distension at birth. ### Medical History - Antenatal investigations including karyotyping and viral studies were unrevealing. - Ultrasound-guided paracentesis was performed. - Echocardiogram and cranial ultrasound were unrema...	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	Neonatal hemangiomatosis with diffuse peritoneal involvement	["Neonatal hemangiomatosis with diffuse peritoneal involvement", "Diffuse neonatal hemangiomatosis involving the peritoneum", "Neonatal peritoneal hemangiomatosis", "Benign lobulated capillary hemangioma of the peritoneum with angiomatosis"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- Repeated antenatal ultrasonography at 23 weeks showed increased ascites with peritoneal thickness and an irregular solid mass arising from the left posterolateral peritoneal surface protruding into the peritoneal cavity.\n- Fetal MRI sh...	ORPHA:2123	pathology_micro	PMC4826694
45	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAGAAawDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - 42-year-old woman. ### Clinical History - Progressive right breast swelling for 3 months. - No prior tuberculosis history or tuberculous contact. - No familial neoplasia history.	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	Granulomatous mastitis	["Idiopathic granulomatous mastitis"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- Initial ultrasound mammogram found lesions of the supero-external quadrant of the right breast classified ACR 4.\n- MRI found a lesional range made of multiple oval formations occupying the entire gland and extending to the skin.\n- Com...	ORPHA:64722	pathology_micro	PMC9793057
46	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAH0AZIDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is a 37-year-old man. ### Presentation - He presented with acute chest pain and breathlessness causing reduced exercise tolerance. - He had no clear provoking factors for venous thromboembolism and no testicular symptoms on history. ### Key Tests - He underwent additional imagin...	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	Testicular seminoma	["Testicular seminoma", "Seminoma of the testis", "Seminomatous germ cell tumor of the testis"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- Computed tomographic pulmonary angiography confirmed major pulmonary embolus with associated acute right heart strain and dilation of the pulmonary trunk.\n- Echocardiogram demonstrated a dilated right heart with impaired right ventricu...	ORPHA:842	ct	PMC8289448
47	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAFeAbADASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is a 16-year-old boy. ### Symptoms and Signs - He presented with a firm, non-mobile left neck mass medial to the sternocleidomastoid muscle. - Flexible endoscopy showed a left submucosal lateral pharyngeal wall mass impinging on the larynx, with normal vocal cord mobility. ### A...	Based on the clinical information and all provided medical images, what diagnoses should be considered for this patient?	Synovial sarcoma of the hypopharynx	["hypopharyngeal synovial sarcoma", "synovial sarcoma", "biphasic synovial sarcoma of the hypopharynx", "biphasic synovial sarcoma"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- Flexible endoscopy demonstrated a lateral normal-mucosa-covered mass displacing the larynx.\n- Flexible endoscopy revealed a left submucosal lateral pharyngeal wall mass impinging on the larynx with normal vocal cord mobility.\n- MRI sh...	ORPHA:3273	mri	PMC5031474
48	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAGiAcgDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient was a 29-year-old woman. ### Symptoms and Signs - The patient presented with anterior chest pain. ### Medical History - She had prior episodes of left pneumothorax at ages 18 and 23 years. ### Laboratory Results - Whole blood cell count and blood chemistry were unremarkable.	Based on the patient's brief clinical history and the provided chest radiograph, CT, and histopathology images, what diagnoses should be considered for this patient?	Stocker type I congenital pulmonary airway malformation	["Stocker type I congenital cystic adenomatoid malformation", "Stocker type I CCAM", "Type I congenital pulmonary airway malformation", "Type I CPAM", "Stocker type I congenital pulmonary airway malformation", "Stocker type I congenital cystic adenomatoid malformation/congenital pulmonary airway malformation", "Type I ...	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- A severe recurrence of the left pneumothorax was identified on chest radiograph.\n- Chest CT scan after inflation of the left lung revealed multiple a medical condition cysts at the base of the left lung with a maximum diameter of 22 mm...	ORPHA:2444	ct	PMC6424061
50	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAGeAbADASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is a 51-year-old woman. ### Symptoms and Signs - She had a 1-year history of nasal obstruction, intermittent epistaxis, headaches, decreasing visual acuity, and diplopia. - There was no nausea, vomiting, or seizure.	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	Solitary plasmacytoma of the sphenoid bone	["Plasmacytoma of the sphenoid bone", "Solitary plasmacytoma", "Solitary bone plasmacytoma of the sphenoid bone", "Skull base solitary plasmacytoma"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- CT scan and MRI showed a large heterogeneous, expansile lesion measuring 75 mm × 54 mm, centered on the sphenoidal bone and the clivus.\n- The lesion was pressing against the optic nerve and the internal carotid artery, involving the na...	ORPHA:86855	ct	PMC10475402
51	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAFaAc4DASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is a 25-year-old man. ### Symptoms and Signs - Chronic diarrhea. - Iron deficiency anemia and protein-losing enteropathy. - Recurrent episodes of abdominal pain and bowel obstruction. ### Prior Evaluation - Prior upper endoscopy and colonoscopy were unrevealing.	Based on the patient's brief clinical history and the provided medical images, especially the pattern seen across the hand photograph, abdominal CT, and small-bowel endoscopy image, what diagnoses should be considered for this patient?	Cryptogenic multifocal ulcerating stenosing enteropathy	["Cryptogenic multifocal ulcerating stenosing enteropathy", "Cryptogenic multifocal ulcerous stenosing enteritis", "CMUSE", "CNSU"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- Magnetic resonance enterography showed mild prominence of jejunal loops without focal abnormality or mucosal enhancement.\n- Laparoscopy revealed multiple jejunal strictures without creeping fat or thickening of the mesentery.", "markdo...	ORPHA:468635	endoscopy	PMC11239156
54	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAFyAbgDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - 55-year-old postmenopausal woman. ### Symptoms and History - Massive vaginal bleeding for 10 days. - Constant abdominal pain with diarrhea and vomiting. - Natural menopause 15 months earlier. - G14P14A0; last delivery 13 years earlier. - No history of molar pregnancy, spontaneous abortion, o...	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	Invasive hydatidiform mole	["invasive mole", "invasive hydatidiform mole", "gestational trophoblastic neoplasia of invasive mole type", "uterine invasive mole"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- Pelvic ultrasonography showed an enlarged uterus the size of 24-week gestation with a heterogeneous mass obliterating the endometrial cavity and a vesicular appearance, and normal ovaries.\n- Abdominopelvic CT scan confirmed a well-dema...	ORPHA:99925	pathology_micro	PMC7812724
57	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAFwAcADASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - A 72-year-old Japanese man. ### Symptoms and Signs - One-month history of dyspnea on exertion and bilateral shoulder pain with gradually increasing difficulty raising both upper limbs. - Neurological examination suggested cervical radicular involvement. ### Laboratory Results - Inflammatory...	Based on the patient's brief clinical history and the provided PET/CT and vascular ultrasound images, what diagnoses should be considered for this patient?	Giant cell arteritis	["GCA", "Large-vessel giant cell arteritis"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- Musculoskeletal ultrasound examination showed no signs of tenosynovitis and bursitis in both shoulders.\n- Musculoskeletal ultrasound examination showed no signs of synovitis.\n- Ultrasonography examination showed absence of movement in...	ORPHA:397	pet	PMC8527715
60	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAFUAcoDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - 15-year-old girl. ### Laboratory Results - Hypochromic microcytic anemia (hemoglobin 8 g/dL). ### Symptoms and History - Two weeks of intermittent fever, cough, dyspnea, and right-sided pleuritic chest pain. - Four prior episodes of pneumonia requiring hospitalization since age 13. - Prior ...	Based on the clinical information and provided medical images, what diagnoses should be considered for this patient?	Benign bronchial glomus tumor	["bronchial glomus tumor", "benign pulmonary glomus tumor", "pulmonary glomus tumor", "glomus tumor of the bronchus", "glomus tumor"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- Contrast-enhanced chest tomography showed bilateral pleural effusions, with the right effusion tabicated and associated thickening of the visceral and parietal pleura.\n- Chest tomography showed basal segmental atelectasis in both left ...	ORPHA:391651	pathology_micro	PMC5067091
62	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAE6AeYDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient was a 10-month-old male infant. ### Symptoms and Signs - The infant presented with swelling noticed by his parents. - There was no noticeable swelling at birth according to the mother.	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	Osteoblastoma	["maxillary osteoblastoma", "osteoblastoma of the maxilla"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- Multi-detector CT showed a mixed radiolucent-radiopaque internal structure of the lesion.\n- Radiographically, the lesion was well defined and expanded from the maxillary crest to the maxillary sinus, perforating the sinus walls.\n- The...	ORPHA:58040	pathology_micro	PMC8927954
63	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAEuA/IDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is a 40-year-old Hispanic woman. ### Symptoms and Signs - The patient presented with a 3-month history of neck pain. - The patient had a bulging lesion in the retromastoid area. ### Medical History - The patient had no significant medical history.	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	Giant cell tumor of the occipital bone	["giant cell tumor of the occipital bone", "occipital bone giant cell tumor", "giant cell tumor involving the occipital bone", "osteoclastoma of the occipital bone", "giant cell tumor of bone of the occipital bone"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- Brain MRI T1-weighted image with gadolinium showed an extradural and contrast-enhancing lesion destroying the inner and outer layers of the right occipital bone, extending into the scalp and posterior fossa.\n- The occipital bone lesion...	ORPHA:363976	mri	PMC9479658
67	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAGiAegDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is a 50-year-old man. ### Symptoms and Signs - He presented with headache for 4 months, progressive unsteadiness of gait for 1 month, and recurrent vomiting for 1 week. - The headache was holocranial, throbbing, almost continuous, disturbed sleep, and was worsened by coughing. - ...	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	Leukoencephalopathy with calcifications and cysts	["Leukoencephalopathy with intracranial calcifications and cysts", "LICAC", "Leukoencephalopathy with Intracranial Calcifications and Cysts syndrome", "Leukoencephalopathy with intracranial calcifications and cysts disease", "LICAC syndrome", "LICAC disease", "Intracranial calcifications and cysts with leukoencephalopa...	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- MRI of the brain showed multiple bilateral cerebral cystic lesions and a large right cerebellar cyst with mass effect compressing the 4th ventricle and brainstem.\n- Diffuse T2 hyperintense lesions were seen bilaterally in the subcortic...	ORPHA:542310	mri	PMC3021936
68	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAFQAqoDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is a 77-year-old female. ### Symptoms and Signs - The patient presented with 4 weeks of progressively worsening bilateral lower extremity weakness. - She also had orthostatic hypotension, rigors, and night sweats. - Her weakness progressed despite initial evaluation and empiric c...	Based on the patient's brief clinical history and especially the provided pathology image(s), what diagnoses should be considered for this patient?	Intravascular large B-cell lymphoma	["IVLBCL", "intravascular large B cell lymphoma", "intravascular diffuse large B-cell lymphoma", "intravascular diffuse large B cell lymphoma"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- Initial CT scans of the head, chest, abdomen, and pelvis showed anasarca in the lower abdomen and upper thighs and no new mass or lymphadenopathy.\n- MRI of the thoracic and lumbar spine with gadolinium showed no canal stenosis, cord co...	ORPHA:98839	pathology_micro	PMC9830303
70	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAIWA7gDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is a 68-year-old man. ### Symptoms and Signs - He presented with a 15-day history of progressive dyspnea, chills, productive cough, and fever. ### Medical History - History of smoking, prior herpes zoster, and inguinal hernia. - No history of thoracic trauma or thoracic surgery....	Based on the patient's brief clinical history and the provided chest imaging and pleural biopsy pathology images, what diagnoses should be considered for this patient?	Pleural actinomycosis	["pleural actinomycosis", "isolated pleural actinomycosis", "thoracic actinomycosis", "thoracic actinomycosis presenting as isolated pleural effusion", "actinomycosis involving the pleura"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- Chest radiography showed a totally whited-out right lung.\n- Chest computed tomography revealed a large amount of right pleural effusion, diffuse pleural enhancement, and multifocal low dense lesions in the right lobe.\n- Chest radiogra...	ORPHA:457095	pathology_micro	PMC8596954
72	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAFAAUwDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is a 72-year-old Caucasian male. ### Symptoms and Signs - The patient presented with severe abdominal pain and hematochezia beginning the night prior to admission. - He also reported fever and sweats shortly before the abdominal pain. ### Medical History - Past history includes ...	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	Inflammatory myofibroblastic tumor	["IMT", "inflammatory myofibroblastic tumour", "inflammatory pseudotumor of myofibroblastic type", "inflammatory myofibroblastic mesenteric tumor"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- Initial computed tomography revealed pancolitis that was suspicious for ischemia versus infectious colitis.\n- A plain abdominal film demonstrated a possible volvulus when abdominal pain increased during the hospital course.\n- Subseque...	ORPHA:178342	pathology_micro	PMC11561171
73	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAGYAWwDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is a 28-year-old man. ### Symptoms and Signs - He developed severe bifrontal headaches for 2 days. - The headaches were acute, throbbing, and associated with blurred vision, diplopia, photophobia, nausea, and vomiting. - The headaches worsened with coughing, bending forward, and ...	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	Cerebral venous sinus thrombosis (CVST)	["cerebral venous sinus thrombosis","CVST","cerebral venous thrombosis","dural venous sinus thrombosis"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- Magnetic resonance venography of the brain showed filling defects within the superior sagittal sinus and right transverse sinus extending into the right jugular vein, consistent with CVST.\n- CT angiography of the chest and abdomen show...	ORPHA:699029	mri	PMC9853928
75	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAEcAVADASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is a 22-year-old woman. ### Symptoms and Signs - After treatment for bilateral septic arthritis, she developed persistent bilateral knee pain worsened by movement, especially climbing stairs. ### Medical History - She had Crohn disease diagnosed earlier that year and had been tr...	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	Bilateral osteonecrosis of the knees	["osteonecrosis of both knees", "bilateral osteonecrosis of the knees", "bilateral knee osteonecrosis", "avascular necrosis of both knees", "bilateral avascular necrosis of the knees"]	[{"phase": "mechanical_pre_model_feedback", "title": "a medical condition Findings", "body": "- Magnetic resonance a medical condition showed multiple a medical condition medullary infarcts in the distal extremity of the femurs, proximal extremity of the tibiae and patellas with no signs of subchondral collapse, consis...	ORPHA:399158	mri	PMC5095578
76	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAI8AsADASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is a 25-year-old woman. ### Symptoms and Signs - She had no abdominal pain, jaundice, or fever when the liver lesions were investigated. ### Medical History - She had relapsed B-acute lymphoblastic leukemia and achieved remission after salvage chemotherapy. - During pretransplan...	Considering this patient's clinical history, liver MRI, and liver biopsy histology, what diagnoses should be considered for this patient?	Inflammatory pseudotumor of the liver	["Hepatic inflammatory pseudotumour", "Hepatic inflammatory pseudotumor", "Liver inflammatory pseudotumour", "Liver inflammatory pseudotumor", "Inflammatory pseudotumor of the liver", "Inflammatory pseudotumour of the liver", "Inflammatory pseudotumor of liver", "Inflammatory pseudotumour of liver", "Hepatic IPT", "Liv...	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- An MRI scan of the heart incidentally detected multiple, bilobar a medical condition lesions.\n- a medical condition MRI showed multiple lesions of varying sizes throughout both lobes of the a medical condition with ill-defined margins ...	ORPHA:90003	mri	PMC5149620
77	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCALQAfADASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is a 29-year-old female with no past medical history. ### Symptoms and Signs - The patient experienced postprandial right hypochondrium pain for 5 months. - She reported burning epigastric discomfort, mild to moderate, triggered by overeating or fatty foods. - The pain was often ...	Based on the patient's brief clinical history and the provided CT angiographic and Doppler ultrasound images, what diagnoses should be considered for this patient?	Median arcuate ligament syndrome	["Median arcuate ligament syndrome", "MALS", "Celiac artery compression syndrome", "Dunbar syndrome"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- Ultrasonography revealed multiple echogenic structures with posterior acoustic shadowing in the gallbladder lumen corresponding to gallstones.\n- On CT angiogram, the median arcuate ligament was compressing the proximal part of the celi...	ORPHA:293208	ct	PMC12018086
80	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAHCAWoDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is 35 years old. - The patient is male. ### Symptoms and Signs - The patient presented with gradual left ear hearing loss over a 1-year duration. - The patient reported left ear fullness over a 1-year duration. - Otologic examination showed a bulging, thickened tympanic membrane....	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	Middle ear neuroendocrine tumor	["well-differentiated Grade 1 neuroendocrine tumor of the middle ear", "middle ear neuroendocrine neoplasm", "grade 1 neuroendocrine tumor of the middle ear", "middle ear carcinoid tumor"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- Contrast-enhanced computed tomography showed a soft tissue density mass localized in the a medical condition ear with extension to the attic, pushing and dislocating the ossicles without evidence of bone invasion.", "markdown": "### Ima...	ORPHA:100084	pathology_micro	PMC9205677
81	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAFgAfoDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is a 70-year-old male. ### Symptoms and Signs - The patient presented with bilateral drooping eyelids, diplopia, and exertional breathlessness. - Symptoms progressed over months and showed fatigability. ### Medical History - No history of hypertension, diabetes, or tuberculosis.	Based on the patient's brief clinical history and the provided chest images, what diagnoses should be considered for this patient?	Thymoma	["Thymic thymoma", "Thymic epithelial tumor (thymoma)", "Anterior mediastinal thymoma"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- Chest X-ray revealed a well-defined, lobulated radio-opaque lesion in the right hemithorax adjacent to the right mediastinum.\n- HRCT thorax showed a well-defined round to oval soft tissue density lesion in the anterior mediastinum, pre...	ORPHA:589;ORPHA:99867	ct	PMC11570893
83	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAEKArIDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is a 17-year-old male. ### Symptoms and Signs - He presented with fever, drenching night sweats, cough, nasal congestion, chest tightness, weight loss, worsening shortness of breath, and intermittent hemoptysis. - He had recent exposure to a COVID-19-positive contact and tested p...	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	Pulmonary-limited ANCA-associated vasculitis	["pulmonary-limited AAV", "pulmonary-limited ANCA-associated vasculitis"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- The initial chest x-ray showed a 5 cm left upper lobe mass and a 3 cm right paratracheal mass.\n- Initial chest CT showed multiple bilateral cavitary lung lesions, with the largest lesion in the left upper lobe measuring 6.5 cm in diame...	ORPHA:156152	ct	PMC8338201
84	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAMWAoQDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	A 72-year-old man presented with severe intermittent spontaneous pain at night in the left maxillary posterior region for 1 week. Symptoms persisted after recent dental treatment, and he later returned with recurrent nocturnal pain and facial paresthesia.	Based on the patient's brief clinical history and the provided CT/CBCT, intraoral, histopathology, and immunohistochemical images, what diagnoses should be considered for this patient?	Diffuse large B-cell lymphoma, not otherwise specified	["Diffuse large B-cell lymphoma, not otherwise specified", "DLBCL-NOS", "DLBCL NOS", "DLBCL, NOS"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- Cone-beam CT showed multiple well-defined hypo-attenuating entities apical to teeth #12–13 and #15 and in the root canal of the residual root of #15, along with an extensive soft tissue mass in the left maxillary sinus extending from th...	ORPHA:544	ct	PMC9010219
88	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAJsA7IDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is a 61-year-old man of Taiwanese/Southeast Asian descent. ### Symptoms and Clinical Course - He initially presented with pulmonary Mycobacterium avium complex infection, fevers, chills, weight loss, diffuse lymphadenopathy, and a rash. - Despite treatment, his systemic illness p...	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	Anti-interferon-gamma autoantibody-associated immunodeficiency syndrome	["Anti-IFN-γ autoantibody-associated immunodeficiency", "Anti-interferon-gamma autoantibody syndrome", "Anti-IFN-γ autoantibody syndrome", "Acquired immunodeficiency due to anti-interferon-gamma autoantibodies", "Anti-IFN-γ immunodeficiency syndrome", "Interferon-gamma autoantibody-associated immunodeficiency", "Anti-I...	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- PET scan revealed diffuse hypermetabolic lymphadenopathy involving supraclavicular, mediastinum, hilar, and axillary lymph nodes.\n- Despite quadruple therapy for disseminated MAC infection, the patient developed pathologic compression ...	ORPHA:284264	pathology_micro	PMC9461271
89	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAJOAuQDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is a 20-year-old female. ### Symptoms and Signs - She presented with deformity and bulging of the anterior chest wall in the sternal area with mild pain. - At operation, the lesion was described as a well-defined hemorrhagic mass without obvious invasion to surrounding tissues. ...	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	Aneurysmal bone cyst	["aneurysmal bone cyst of the sternum", "sternal aneurysmal bone cyst", "ABC of the sternum"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- Chest X-ray and CT scan confirmed a large mass with destruction of the sternum.\n- Preoperative chest X-ray and CT scan showed a large mass with multiple areas of low attenuation that had compressed the heart but without obvious invasio...	ORPHA:480553	ct	PMC5337383
90	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAEWA8wDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - 18-year-old female. ### Relevant History - Prior history of a treated non-breast malignancy. - Now presents with a newly detected mass in the left breast.	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	Metastatic rhabdomyosarcoma to the breast	["breast metastasis from rhabdomyosarcoma", "metastatic rhabdomyosarcoma of the breast", "rhabdomyosarcoma metastatic to the breast", "secondary rhabdomyosarcoma in the breast", "metastatic alveolar rhabdomyosarcoma to the breast", "breast metastasis from alveolar rhabdomyosarcoma"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- Breast ultrasonography showed a 2.3 cm sized circumscribed oval hyperechoic mass with central hypoechoic portion in the left breast.\n- Chest, abdominal, and pelvic CT scans and FDG-PET/CT were performed for metastatic disease evaluatio...	ORPHA:780	pathology_micro	PMC3800733
91	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAFuAXQDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The index patient is a 13-year-old boy of Korean ancestry. ### Symptoms and Signs - He presented with recurrent abdominal pain, frequent diarrhea, and poor weight gain. ### Medical History - He had a 5-year history of these symptoms. - He had prior intussusception surgery and a history of a...	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	Cystic fibrosis	["CF", "cystic fibrosis"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- Water’s view radiography demonstrated right frontal and bilateral maxillary sinusitis.\n- Plain chest radiography demonstrated suspicious bronchiectatic lesions in both lung fields.\n- Chest CT demonstrated subsegmental atelectasis in t...	ORPHA:586	ct	PMC8649608
92	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAFIAjwDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is a 64-year-old male. ### Symptoms and Signs - The patient presented with right colic pain, abdominal distention, and diarrhea. ### Medical History - He had diabetic nephropathy and underwent ABO-incompatible kidney transplantation 6 years earlier. - He remained on long-term im...	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	Gastrointestinal stromal tumor	["GIST", "gastrointestinal stromal tumor", "gastrointestinal stromal tumour"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- Initial non-contrast-enhanced CT scan revealed a solitary tumor with a diameter of 11 cm in the lower abdomen without distant metastasis.\n- CT colonography showed that the huge tumor originated from the small intestine and expanded out...	ORPHA:44890	ct	PMC6448240
94	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAEeArADASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is a 19-year-old Chinese male. - Height 174 cm; weight 52 kg; BMI 17.18 kg/m^2. ### Symptoms and Signs - Recurrent limb convulsions for 1 year with numbness. - Gradual 5-kg weight loss over the year. - No edema, chronic diarrhea, abdominal pain, nausea, vomiting, headache, or diz...	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	Primary intestinal lymphangiectasia	["The final diagnosis was primary intestinal lymphangiectasia (PIL).", "primary intestinal lymphangiectasis", "primary intestinal lymphangiectasia (PIL)", "PIL"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- Parathyroid B-mode ultrasound revealed a hypoechoic nodule with a clear boundary, regular shape, and few blood vessels.\n- MRI showed an abnormal-signal nodule in front of the right middle abdominal psoas muscle, considered an enlarged ...	ORPHA:90362	pathology_micro	PMC9254181
96	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAFGAcYDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is 35 years old. - The patient is female. - The patient is 12 days postpartum after her first delivery. ### Symptoms and Signs - The patient developed 3 days of progressive dyspnea after delivery. - She later showed clinical and biochemical signs of tissue hypoperfusion, includin...	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	Peripartum cardiomyopathy	["PPCM", "peripartum cardiomyopathy", "postpartum cardiomyopathy"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- Transthoracic echocardiography initially showed severe mitral insufficiency and mild left ventricular dysfunction with a left ventricular ejection fraction of 43%.\n- Initial echocardiography demonstrated hypokinesis of lateral segments...	ORPHA:563	echocardiography	PMC4625822
99	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAFgAVQDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - 27-year-old female. ### Symptoms and Signs - Presented with three days of bilateral focal neurological deficits in the arms and legs. - Weakness improved after high-dose steroids. ### Medical History - History of a systemic autoimmune disease treated with mycophenolate and hydroxychloroquin...	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	Neuropsychiatric systemic lupus erythematosus (NPSLE)	["Neuropsychiatric systemic lupus erythematosus", "Neuropsychiatric SLE", "NPSLE"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- Computed tomography angiography of the brain showed hypoattenuation in the left frontal convexity.\n- MRI brain with contrast was notable for acute ischemic changes in the watershed area among the anterior, middle, and posterior cerebra...	ORPHA:536	mri	PMC10581839
101	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAFUAWIDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - 65-year-old Hispanic man. ### Symptoms and Signs - Progressive frontal/biparietal headache for 1 month with photophobia, diplopia, decreased visual acuity, right ptosis, nausea, and vomiting. - Unintentional 32-lb weight loss over 2 months. - Examination showed internuclear ophthalmoplegia, ...	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	Pituitary (sellar/clival) metastasis from hepatocellular carcinoma	["pituitary metastasis from hepatocellular carcinoma", "sellar metastasis from hepatocellular carcinoma", "metastatic hepatocellular carcinoma to the pituitary", "pituitary metastatic HCC"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- Magnetic resonance imaging of the brain showed a mass in the pituitary region involving the sella as well as the clivus.\n- A repeat MRI revealed that the mass measured 3.1 cm × 3.2 cm × 4.4 cm, originated from the clivus, extended into...	ORPHA:88673	mri	PMC4518437
104	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAGOAeQDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is a 46-year-old woman. ### Symptoms and Signs - She had flank pain, an abdominal lump, and intermittent hematuria for 6 months. - She did not have fever or weight loss. ### Laboratory Results - Hematological and biochemical parameters were normal. - Urine microscopy showed defo...	Based on the patient's brief clinical history and the provided abdominal CT and histopathology images, what diagnoses should be considered for this patient?	Inflammatory myofibroblastic tumor with malignant transformation	["inflammatory myofibroblastic tumor with malignant transformation", "inflammatory myofibroblastic tumour with malignant transformation", "retroperitoneal inflammatory myofibroblastic tumor with malignant transformation", "retroperitoneal inflammatory myofibroblastic tumour with malignant transformation"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- CT scan of the abdomen showed a large irregular well-defined heterogeneous lesion occupying the left hypochondrium, lumbar and supraumbilical regions, measuring approximately 16 × 13.6 × 12.1 cm, with predominant cystic portions and no ...	ORPHA:178342	pathology_micro	PMC1276822
105	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAFCA84DASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is 33 years old. - The patient is male. ### Symptoms and Signs - The patient presented with headache, balance disturbance, and back pain.	Based on the patient's brief clinical history and the provided brain MRI and histopathology images, what diagnoses should be considered for this patient?	Intracranial dural plasmacytoma	["intracranial dural plasmacytoma", "posterior fossa dural plasmacytoma", "plasma cell tumor of the dura", "intracranial plasmacytoma"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- MRI revealed an occipital extra- axial mass with a dural tail.\n- MRI demonstrated a posterior fossa mass located behind the cerebellum, measuring 31.3 x 31.2 x 23.0 mm, that enhanced post contrast.\n- The mass had a similar appearance ...	ORPHA:29073	mri	PMC3097756
106	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAGoAawDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is a 3-day-old female neonate. - Birth weight was 3416 g. ### Clinical Background - The neonate was brought for evaluation of a congenital right-eye abnormality. - The left eye appeared grossly normal on initial examination. - Ultrasonography of the urinary system showed mild rig...	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	Cryptophthalmia	["Cryptophthalmos", "Cryptophthalmia", "Cryptophthalmia, congenital", "Cryptophthalmos, congenital", "unilateral complete cryptophthalmos"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- B-scan ultrasonography of the right eye revealed the absence of a posterior chamber and membranous lens, a shallow anterior chamber, and a posterior staphyloma.\n- B-scan ultrasonography of the left eye revealed a central flat anterior ...	ORPHA:98562	clinical_exam	PMC10363858
107	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCALAA+YDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is a 37-year-old African American woman. - She migrated to the USA from Jamaica 5 years before presentation. ### Symptoms and Signs - She presented with 6 weeks of persistent dry cough, intermittent low-grade fever, night sweats, fatigue, weakness, and dyspnea on exertion. - Ther...	Based on the patient's brief clinical history and the provided chest CT and lung biopsy pathology images, what diagnoses should be considered for this patient?	Cryptogenic organizing pneumonia	["Bronchiolitis obliterans organizing pneumonia", "BOOP", "COP"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- A chest radiograph showed nodular infiltrates in bilateral upper lobes of the lungs and perihilar fullness.\n- CT scan of the chest showed extensive bilateral hilar and mediastinal lymphadenopathy with areas of perihilar and peripheral ...	ORPHA:1302	ct	PMC1995203
108	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAEYA2QDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient was a 71-year-old female. ### Symptoms and Signs - The patient presented with slight fever, night sweats, and dyspnea at admission. - Autoimmune disease was initially considered during the workup. ### Laboratory Results - Initial laboratory examination showed a remarkably high L...	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	Intravascular diffuse large B-cell lymphoma	["Intravascular diffuse large B-cell lymphoma", "IVLBCL", "Intravascular lymphoma", "Angiotropic large B-cell lymphoma", "Angiotropic lymphoma", "Intravascular B-cell lymphoma", "Intravascular diffuse large B-cell lymphoma, disease", "Intravascular diffuse large B-cell lymphoma, syndrome", "Large B-cell lymphoma, intra...	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- Chest CT and X-ray showed ground-glass opacity on the bilateral lungs.\n- Brain magnetic resonance imaging revealed subacute cerebral infarction in the right corona radiata.\n- After steroid pulse therapy and plasma exchange, ground-gla...	ORPHA:98839	ct	PMC7985940
110	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAIGAtQDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - 9-year-old girl with underweight and moderate wasting. ### Symptoms and Signs - Two weeks of right upper quadrant abdominal pain with decreased appetite and vomiting. - Weight loss, malaise, and low-grade intermittent fever. ### Laboratory Results - Leukocytosis with marked eosinophilia. - ...	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	Hepatic tuberculosis	["Liver tuberculosis", "Hepatic TB", "Liver TB", "Tuberculosis of the liver"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- Abdominal ultrasound showed hepatomegaly with abnormal echo pattern and abnormal cystic changes.\n- Abdominal CT scan showed hepatic nodules without calcification with multiple cysts and small daughter cysts forming a communicating hypo...	ORPHA:3389	pathology_micro	PMC7039246
112	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAJ+A5YDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is an 82-year-old man. ### Symptoms and Course - In 2008, he presented with mild anemia, bilateral flank pain, and night sweats. - He was followed for a chronic multisystem illness over several years. - He remained clinically stable for long periods despite ongoing evaluation. #...	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	Erdheim-Chester disease	["Erdheim Chester disease", "Erdheim-Chester histiocytosis"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- Initial plain abdominal CT revealed non-obstructive right renal stones, minimal retroperitoneal fat stranding in the peri-renal and aortic areas, and mild bilateral hydronephrosis.\n- A follow-up contrast-enhanced abdominal CT taken 2 y...	ORPHA:35687	ct	PMC8688944
113	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAEoAZADASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - 68-year-old man. ### Clinical Presentation - A large abdominal mass was discovered incidentally during evaluation for lower-limb vascular insufficiency. - He had no abdominal pain. - Blood tests were within normal limits.	Based on the clinical information and provided medical images, what diagnoses should be considered for this patient?	1. Gastric gastrointestinal stromal tumor (gastric GIST) 2. Gastric duplication cyst 3. Cystic pancreatic neoplasm 4. Pancreatic pseudocyst 5. Cystic lymphangioma 6. Cystic mesothelioma 7. Cystic mucinous retroperitoneal tumor 8. Exogastric leiomyoblastoma / leiomyosarcoma 9. Cystic teratoma 10. Other cystic abdominal ...	["gastric gastrointestinal stromal tumor", "gastric gastrointestinal stromal tumour", "gastric GIST", "gastrointestinal stromal tumor of the stomach", "gastrointestinal stromal tumour of the stomach", "cystic gastric GIST", "cystic gastrointestinal stromal tumor of the stomach", "cystic gastrointestinal stromal tumour ...	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- Ultrasonography showed a well-defined large cystic mass with several membranous septa with a diameter of approximately 12 cm in the right hypochondrium.\n- Computed tomography scan demonstrated a large cystic lesion adjacent to the righ...	ORPHA:44890	ct	PMC3439949
114	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAHkAqwDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is a 79-year-old Caucasian man. ### Symptoms and Signs - He had a six-month history of lower urinary tract symptoms, including urgency, frequency, nocturia, difficulty initiating urination, and eventual urinary retention requiring catheterization. - On later readmission, he prese...	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	Granulomatous fungal prostatitis due to paracoccidioidomycosis	["granulomatous fungal prostatitis due to paracoccidioidomycosis","paracoccidioidomycotic prostatitis","prostatic paracoccidioidomycosis","paracoccidioidomycosis involving the prostate","chronic granulomatous prostatitis due to paracoccidioidomycosis","fungal granulomatous prostatitis caused by Paracoccidioides"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- Radiological evaluation at the start of antifungal treatment revealed involvement of both pulmonary lobes with preservation of the apices.\n- Thoracic radiography on readmission showed bilaterally diffuse nodular reticular interstitial ...	ORPHA:73260	pathology_micro	PMC3668196
115	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAFGAawDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is an 8-year-old Moroccan girl. ### Symptoms and Signs - She presented with painful swelling of both forearms, beginning on the left and appearing on the right 6 months later. - Pain progressed despite nonsteroidal anti-inflammatory drugs and narcotic analgesics. ### Medical His...	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	Bilateral forearm eosinophilic granuloma (Langerhans cell histiocytosis of bone)	["bilateral forearm eosinophilic granuloma", "eosinophilic granuloma of the bilateral forearms", "Langerhans cell histiocytosis of the bilateral forearm bones", "osseous Langerhans cell histiocytosis involving both forearms"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- Plain radiographs showed an osteolytic lesion of the upper one-third of the right ulna.\n- Plain radiographs showed an osteolytic lesion of the upper two-thirds of the left radius.\n- On both forearms the radiographs did not show minera...	ORPHA:389	pathology_micro	PMC6423802
116	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAFSA0wDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is a 31-year-old Vietnamese woman. ### Symptoms and Signs - Progressive abdominal distention for 2 months. - Moderate ascites was present on examination. ### Medical History - No marked personal or family medical history. ### Clinical Course - Imaging showed an intra-abdominal ...	Based on the patient's brief clinical history and the provided CT and pathology/immunohistochemistry images, what diagnoses should be considered for this patient?	Solitary fibrous tumor	["Hemangiopericytoma"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- Abdominal ultrasound revealed a well-defined hyperechoic mass in the left lumbar region, with intratumoral cysts and dilation of the surrounding blood vessels.\n- Abdominal ultrasound detected large volumes of free abdominal fluid and a...	ORPHA:2126	ct	PMC8861309
117	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAKKAegDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is a 30-year-old male originally from East Timor. ### Symptoms and Signs - He re-presented with left iliac fossa pain, dysuria, and 4 weeks of increasing painful testicular swelling. ### Laboratory Results - Urinalysis initially showed leucocytes and nitrites. - C-reactive prote...	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	Urogenital tuberculosis	["Genitourinary tuberculosis", "Extrapulmonary tuberculosis predominantly involving the genitourinary tract", "Urogenital TB", "GU tuberculosis"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- Initial ultrasound demonstrated a heterogeneous lesion centred on the left epididymis extending into the left testis.\n- Serial ultrasound scans showed progressive epididymis and testicular hypoechoic lesions consistent with tuberculosi...	ORPHA:645874	ct	PMC9976721
118	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAKsAWIDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is a 43-year-old man. ### Symptoms and Signs - He had a 10-year history of a slowly progressive left outer infraclavicular mass. - He had difficulty flexing the left arm, with numbness and pain in the left middle and index fingers. - Use the provided imaging and histology to rank...	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	Desmoid tumor	["Desmoid tumour", "Aggressive fibromatosis", "Desmoid-type fibromatosis", "Fibromatosis, desmoid", "Extra-abdominal desmoid tumor"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- MRI of the neck including the thoracic inlet revealed a well-defined brachial plexus mass that was isointense to muscle on TIW sequences and of mixed signal intensity on T2W sequences and was straddling the brachial plexus.", "markdown"...	ORPHA:873	mri	PMC3694380
120	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAJ4AwQDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is a 77-year-old woman. ### Medical History - The patient has a history of Sjögren syndrome. - She has no history of diabetes or hypertension. - There was no family history of malignant disease. ### Clinical Summary - A lesion was found incidentally and enlarged gradually during...	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	Benign diaphragmatic schwannoma	["Benign diaphragmatic schwannoma","Diaphragmatic schwannoma","Primary diaphragmatic schwannoma","Benign schwannoma of the diaphragm","Schwannoma of the diaphragm","Diaphragmatic neurilemmoma"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- A preventive esophagogastroduodenoscopy 2 years and 7 months prior revealed a 10 mm submucosal tumor-like lesion in the fornix.\n- Contrast enhanced CT revealed a low density, round mass of approximately 20 mm located between the upper ...	ORPHA:252164	pathology_micro	PMC7678197
121	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCALeArgDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is a 32-year-old woman. - The patient is gravida 2, para 2. ### Symptoms and Signs The patient presented with vaginal bleeding and abdominal discomfort for two months. ### Medical History - She had a prior history of uterine surgery for fibroids. ### Laboratory Results - Labora...	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	Disseminated peritoneal leiomyomatosis	["Leiomyomatosis peritonealis disseminata", "Peritoneal leiomyomatosis disseminata", "LPD", "Leiomyomatosis peritonealis disseminata (LPD)", "Disseminated peritoneal leiomyomatosis (LPD)"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- Pelvic ultrasonography detected an indeterminate left adnexal mass measuring 11 × 9.5 cm with normal Doppler.\n- Magnetic resonance imaging demonstrated multiple pelvic tumors closely attached to the uterus and peritoneum, measuring 13 ...	ORPHA:71274	pathology_micro	PMC8131390
122	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAE0AbADASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is sixty one years old. - The patient is female. ### Symptoms and Signs - The patient presented with pain in the left hypochondrium with dyspepsia and heart burn for the past one year. - The abdominal pain was dull aching, intermittent in nature, increased after meals, and resolv...	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	Isolated hydatid cyst of spleen	["Splenic hydatid cyst", "Hydatid cyst of the spleen", "Isolated splenic hydatid cyst"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- X-ray chest and abdomen were unremarkable.\n- Abdominal ultrasonography showed a well defined a medical condition lesion of about 46 ml volume in the splenic parenchyma near the splenic hilum with thick internal membranes and echoes.\n-...	ORPHA:400	ct	PMC5067297
123	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAFsAWYDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is a 35-year-old man. ### Symptoms and Signs - He had gradually progressive difficulty in walking for one and a half years due to dragging of the right foot. - He had spontaneous painful drawing up of the legs in response to stimuli while lying down. - He had increased urinary fr...	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	Astrocytoma	["brain astrocytoma", "cerebral astrocytoma", "diffuse astrocytoma", "low-grade astrocytoma", "grade II astrocytoma", "astrocytoma, grade II", "grade 2 astrocytoma"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- MRI scans of the cervical and thoracic regions were normal.\n- MRI of the lumbosacral spine showed disc prolapse with minimal compression over the thecal sac at L4-L5 level.\n- A CT scan of the brain showed a large iso- to hypo-dense ma...	ORPHA:94	mri	PMC2771986
124	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAJcA1YDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is an 18-year-old Japanese man. ### Symptoms and Signs - The patient presented with a 4-day history of fever, neck pain, and painful swallowing. - During hospitalization, additional systemic abnormalities developed. ### Medical History - He had been treated for a febrile inflamm...	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	Recurrent Kawasaki disease in an adult	["recurrent Kawasaki disease in an adult","adult recurrent Kawasaki disease","adult recurrence of Kawasaki disease"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- Contrast-enhanced CT revealed multiple areas of cervical lymphadenopathy and low-density areas without ring enhancement in the retropharyngeal space.\n- On day 4, MRI showed a retropharyngeal area that was isointense on T1-weighted imag...	ORPHA:2331	ct	PMC5596287
127	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAI+Aa4DASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is a 54-year-old woman. ### Symptoms and Signs - She presented with a 10-year history of progressively worsening pain in the left little finger, with marked tenderness to palpation. - There was no prior trauma.	Based on the patient's brief clinical history and the provided preoperative images (clinical photograph, dermoscopy, and hand radiograph), what diagnoses should be considered for this patient? Do not rely on postoperative or histopathology confirmation.	Glomus tumor	["glomus body tumor", "glomus tumor of the finger pulp", "digital glomus tumor"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- Polarized contact dermoscopy showed peripheral clearing of the reddish color, disclosing a yellow to white background with multiple telangiectasias on the surface.\n- X-ray study of the left hand showed no bony lesions.\n- Radiograph sh...	ORPHA:391651	dermoscopy	PMC6035803
130	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAJGAzQDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is a 49-year-old woman. ### Medical History - The patient had prior surgery for uterine cervical cancer 14 years earlier. ### Laboratory Results - Blood counts showed mild leukopenia and mild anemia. ### Clinical Presentation - The patient presented with a 5-year history of pro...	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	Parotid gland MALT lymphoma	["parotid gland MALT lymphoma", "salivary gland MALT lymphoma", "mucosa-associated lymphoid tissue lymphoma of the parotid gland", "extranodal marginal zone B-cell lymphoma of MALT type involving the parotid gland", "parotid extranodal marginal zone lymphoma", "parotid gland MALT lymphoma with amyloid deposition", "sal...	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- Ultrasonography showed multiple, round, hypoechoic masses up to 2 cm in diameter with punctate calcifications in the bilateral parotid glands.\n- Color Doppler imaging showed no significant blood flow signals within the hypoechoic masse...	ORPHA:52417	mri	PMC11456814
134	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCADyAVwDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is 33 years old. - The patient is male. ### Symptoms and Signs - The patient had recurrent skin lesions for 6 months. - He also had a 1-year history of bronchial asthma. ### Laboratory Results - Peripheral blood eosinophilia was present. - Parasitic infection studies were negati...	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	Wells syndrome	["Eosinophilic cellulitis"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- A computed tomography scan of the chest did not show any abnormalities.", "markdown": "### Imaging Findings\n- A computed tomography scan of the chest did not show any abnormalities."}]	ORPHA:901	pathology_micro	PMC5991892
135	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAFAAewDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - 65-year-old postmenopausal woman from Ethiopia. ### Symptoms and Signs - Vaginal bleeding for 2 months, progressing from intermittent/minimal to continuous/significant. - Foul-smelling vaginal discharge, pelvic pain, dysuria, easy fatigability, and loss of appetite.	Based on the clinical information and provided medical images, what diagnoses should be considered for this patient?	Primary adenoid cystic carcinoma of the cervix	["Adenoid cystic carcinoma of the cervix", "Cervical adenoid cystic carcinoma", "ACC of the cervix", "Adenoid cystic carcinoma, cervical", "Cervical ACC", "Adenoid cystic carcinoma of uterine cervix", "Cervix adenoid cystic carcinoma", "Adenoid cystic carcinoma (cervix)"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- Abdominopelvic ultrasound showed a heterogeneously hypoechoic a medical condition mass measuring 8.6×6.7 cm extending to the lower uterine segment and upper two-thirds of the vagina, with mild hydrometria and features likely secondary t...	ORPHA:213823	pathology_micro	PMC11533679
136	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAKOAawDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is a 22-year-old man. ### Symptoms and Signs - He presented with shortness of breath and chest discomfort. ### Laboratory and Pathology Context - Laboratory tests showed elevated tumor markers and enzyme levels. - Tissue sampling from an enlarged lymph node was performed, with a...	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	NUT midline carcinoma	["NUT carcinoma", "NUT-associated midline carcinoma", "NUT midline carcinoma with BRD4-NUT translocation", "BRD4-NUT translocation-associated NUT carcinoma"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- At presentation the patient had a large mediastinal mass with skeletal and lymph node metastases.\n- At a medical condition, CT scan showed a bulky mediastinal mass with involvement of the right lung hilum, compression of the right supe...	ORPHA:443167	pathology_micro	PMC5390376
137	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAI2ArgDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - 74-year-old woman. ### Symptoms and Signs - Presented with 10 days of right-eye subacute visual decline. - Associated systemic symptoms included dizziness, metallic taste, reduced appetite, shortness of breath, and night sweats. - No prior ocular history. ### Medical History - Hypertension,...	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	B-cell acute lymphoblastic leukemia	["B-cell acute lymphoblastic leukemia", "B-ALL", "B-cell ALL", "Acute lymphoblastic leukemia, B-cell type", "B-lymphoblastic leukemia", "B-cell acute lymphoblastic leukaemia", "B-ALL (B-cell acute lymphoblastic leukemia)", "B-cell acute lymphoid leukemia"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- Autofluorescence of the right eye showed hypoautofluorescent patches corresponding to cotton wool spots and hemorrhages, a stippled hyperautofluorescent area in the superior macula corresponding to retinal pigment epithelium changes, an...	ORPHA:99860	fundus	PMC8242964
139	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAK+AsADASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is a 30-year-old male. ### Symptoms and Signs - The patient initially presented with loss of body hair. - Clinical examination revealed loss of axillary and facial hair. - Baseline ophthalmologic examination showed preserved visual acuity. ### Medical History - No previous medic...	Based primarily on the MRI and CT images, with the brief clinical history only as supporting context, what diagnoses should be considered for this patient?	Suprasellar meningeal melanocytoma with leptomeningeal seeding	["suprasellar meningeal melanocytoma with leptomeningeal seeding", "suprasellar melanocytoma with leptomeningeal seeding", "primary sellar melanocytoma with cerebral and spinal leptomeningeal spread", "sellar melanocytoma with leptomeningeal spread", "suprasellar melanocytoma with cerebral and spinal leptomeningeal spr...	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- Initial brain and sella MRI showed a large suprasellar mass with cerebral and spinal leptomeningeal spread.\n- MRI demonstrated a large suprasellar mass continuous with the infundibulum of the pituitary gland that was heterogeneously hy...	ORPHA:252046	mri	PMC8523264
140	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAGyA1gDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - 31-year-old male with newly diagnosed HIV infection and severe immunosuppression. ### Symptoms and Clinical Course - Presented with a recurrent buttock ulceration. - Over time, additional extracutaneous disease was identified, including thoracoabdominal involvement. - Tissue sampling was obt...	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	Systemic ALK-negative anaplastic large cell lymphoma	["Systemic ALK-negative anaplastic large cell lymphoma", "Systemic ALK-negative ALCL", "ALK-negative anaplastic large cell lymphoma, systemic type", "Systemic anaplastic large cell lymphoma, ALK-negative", "Systemic ALCL, ALK-negative"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- CT scans revealed hepatomegaly and multiple mediastinal and axillary lymph nodes of varied dimensions.\n- A PET scan one month after admission revealed potential reactive lymph nodes related to the buttock lesion.\n- Five months after i...	ORPHA:300903	pathology_micro	PMC10627364
141	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAEAAVgDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is 59 years old. - The patient is female. ### Symptoms and Signs - The patient presented with dyspepsia leading to endoscopy. - She also had left lower back pain for 2 months. - She had no urinary or bowel symptoms. ### Medical History - The patient had a long-standing history o...	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	Renal cell carcinoma	["renal carcinoma", "kidney cancer", "primary renal cell carcinoma", "RCC"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- Endoscopy showed a 5 mm sessile nodule in the fundus of the stomach.\n- a medical condition tomography of the abdomen showed an 18 × 15 cm tumour originating from the left kidney.\n- The a medical condition mass seen on CT scan does not...	ORPHA:217071	endoscopy	PMC3502775
144	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAEQAeYDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is 35 years old. - The patient is female. ### Symptoms and Signs - The patient had a 1-year history of severe difficulty opening the mouth. - She had long-standing progressive swelling of the right side of the face. ### Medical History - The patient previously underwent facial s...	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	Congenital infiltrating lipomatosis of the face	["Congenital infiltrating lipomatosis of the face", "CIL-F", "Congenital infiltrating lipomatosis involving the face"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- Orthopantomogram revealed marked expansion and remodeling of bones forming the right temporomandibular joint with associated temporomandibular joint ankylosis.\n- Computed tomography showed enlargement of the right foramen ovale, greate...	ORPHA:583097	ct	PMC7518480
146	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAHoAcYDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is a 32-year-old woman. ### Symptoms and Signs - She presented with a second right-sided tension pneumothorax two weeks after prior drainage therapy. ### Medical History - She had no relevant prior pulmonary symptoms. - She was a never-smoker. - Alpha-1-antitrypsin levels were w...	Based on the clinical information and provided medical images, what diagnoses should be considered for this patient?	Lymphangioleiomyomatosis	["pulmonary lymphangioleiomyomatosis", "LAM"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- Chest X-ray at the day of admission showed a tension pneumothorax on the right side with emphysematous changes, cysts and fibrous strands homogenously distributed over both lungs.\n- Chest CT scan after chest tube insertion revealed mul...	ORPHA:538	pathology_micro	PMC6586772
149	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAJ4AbQDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is an 80-year-old man. ### Symptoms and Signs - He had a 12 to 18-month history of a swelling over the radial aspect of the thumb. - The swelling was initially painless but later became painful when leaning the hand against a hard surface.	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	Benign schwannoma	["Benign Schwannoma"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- Ultrasound demonstrated a 20 mm × 9 mm × 13 mm non-compressible lesion with mixed echogenicity and moderate internal vascularity in the thumb.\n- On ultrasound, the interphalangeal and metacarpophalangeal joints of the thumb and the ten...	ORPHA:252164	mri	PMC8671817
150	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAO4AxQDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is a 48-year-old woman. ### Symptoms and Signs - She presented with a painless mass in the left breast. - No axillary lymph nodes were palpable. ### Clinical Course - She underwent diagnostic evaluation and tissue sampling for the breast lesion.	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	Primary breast diffuse large B-cell lymphoma	["primary breast diffuse large B-cell lymphoma", "diffuse large B-cell lymphoma of the breast", "breast diffuse large B-cell lymphoma", "primary breast DLBCL", "primary lymphoma of the breast, diffuse large B-cell type", "primary lymphoma of the breast", "diffuse large B-cell lymphoma"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- Mammography showed normal findings (category 1) with no mass or calcification.\n- Breast ultrasonography revealed an irregular hypoechoic mass of 23 mm in diameter with angular and indistinct margins, suggestive of a malignant tumor.\n-...	ORPHA:544	pathology_micro	PMC7644561
151	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAF+A6YDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is 63 years old. - The patient is male. ### Symptoms and Signs - The patient presented with chronic pustular skin lesions involving the feet and groin. - He reported polyarthralgia and chest pain. ### Medical History - No significant past medical history was reported. ### Labor...	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	SAPHO syndrome	["Synovitis-acne-pustulosis-hyperostosis-osteitis syndrome"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- A pelvis CT scan revealed a medical condition and sclerosis on the right side of the symphysis pubis, evoking Paget disease.\n- Thorax and abdomen CT scan revealed a medical condition of the manubrium with irregularities and sclerosis o...	ORPHA:793	ct	PMC11143798
153	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAD2AtgDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is a 30-year-old man. - The patient experienced a 26-pound weight loss over 2 months before presentation. ### Symptoms and Signs - The patient presented with rapidly progressive bilateral vision loss and diplopia for 2 months. - He also had headaches, nausea, and vomiting. ### M...	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	Myeloid sarcoma	["intracranial myeloid sarcoma of the sellar and parasellar region", "skull base myeloid sarcoma", "intracranial myeloid sarcoma", "sellar myeloid sarcoma", "granulocytic sarcoma", "chloroma"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- Imaging initially revealed a sellar mass thought to be consistent with a pituitary lesion but without the typical appearance of a pituitary macroadenoma.\n- Preoperative MRI showed a lobulated extra-axial mass centered in the sella turc...	ORPHA:86850	mri	PMC9168333
157	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAMUAaoDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - 40-year-old man. ### Presentation - Presented initially with unprovoked right lower-extremity deep venous thrombosis, followed by melena after anticoagulation. - CT showed a gastric abnormality with pulmonary emboli and right renal vein thrombosis. ### Selected Laboratory Data - Severe iron...	Based on the patient's brief clinical history and the provided upper endoscopy and gastric biopsy images, what diagnoses should be considered for this patient?	Ménétrier disease	["Ménétrier's disease", "ménétrier disease"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- Venous ultrasound revealed an acute, occluding thrombus of the patient’s right popliteal, tibial, and peroneal veins.\n- Abdominal CT scan revealed mass-like transmural thickening of the gastric antral and pyloric walls with tumor protr...	ORPHA:2494	endoscopy	PMC6335789
158	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCALmAsADASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is a 53-year-old man. - He was immunologically healthy. ### Symptoms and Signs - He presented with nasal obstruction and frequent epistaxis for 3 months. - Endoscopic examination showed a polypoid mass in the right nasal cavity extending toward the choana. - The excised lesion or...	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	Malignant peripheral nerve sheath tumor	["Malignant schwannoma", "MPNST"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- Paranasal sinus computed tomography showed a 2.5 cm long heterogeneously enhanced mass filling the right nasal cavity with extension to the right choana and nasopharynx and some erosion of the septal bone.\n- Paranasal sinus magnetic re...	ORPHA:3148	pathology_micro	PMC4172938
161	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAJEAdIDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - 15-month-old female infant. - Weight and height below the 5th percentile for age. ### Symptoms and Signs - Recurrent respiratory infections since birth. - Poor weight gain with cough, breathing difficulty, and feeding difficulty. - On examination: pallor, tachypnea, irritability, and finger ...	Based on the patient's brief clinical history and the provided chest radiograph and cardiac CT angiography images, what diagnoses should be considered for this patient?	Double outlet right ventricle	["double-outlet right ventricle", "DORV"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- Chest radiograph revealed significant cardiomegaly with patchy lung infiltrates bilaterally.\n- Echocardiography identified a a medical condition with both the aorta and pulmonary artery originating from the right ventricle and a large ...	ORPHA:3426	ct	PMC11705528
162	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAMSAwQDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is a 52-year-old female. ### Symptoms and Signs - Rapid-onset bilateral upper eyelid oedema - Decline in visual acuity - Headaches ### Medical History - Prior breast cancer - Undergoing chemotherapy at presentation	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	Systemic sarcoidosis with lacrimal gland involvement	["Sarcoidosis", "Systemic sarcoidosis", "Orbital sarcoidosis", "Lacrimal gland sarcoidosis"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- Initial cerebral and orbital CT scan showed diffusely enlarged and infiltrated appearance of both lacrimal glands with post-contrast enhancement and extraconal fat infiltration.\n- Orbital MRI demonstrated asymmetric infiltration of the...	ORPHA:797	mri	PMC11087900
163	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAGIBDgDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is a 44-year-old woman. ### Symptoms and Signs - She presented with epigastric burning pain wrapping around her chest to her back, with diaphoresis, nausea, and vomiting. - She denied fevers, hematemesis, dysuria, or vaginal discharge. ### Medical History - Past history included...	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	Tako-Tsubo cardiomyopathy	["Takotsubo cardiomyopathy", "Tako-tsubo cardiomyopathy", "stress cardiomyopathy", "stress-induced cardiomyopathy"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- Computed tomography abdomen/pelvis with intravenous contrast demonstrated gallbladder wall thickening with gallstones in both the gallbladder and cystic duct.\n- Cardiac magnetic resonance imaging was significant for apical ballooning o...	ORPHA:66529	mri	PMC7219991
164	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAGOAcoDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is a 37-year-old man. - The patient is Iraqi. - The patient has a body mass index of 21. ### Symptoms and Signs - The patient presented with progressive dyspnea on exertion for two years. - The patient had an associated dry cough. ### Laboratory Results - Transthoracic echocardi...	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	Idiopathic pleuroparenchymal fibroelastosis	["IPPFE", "Idiopathic pleuroparenchymal fibroelastosis (IPPFE)", "pleuroparenchymal fibroelastosis", "PPFE"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- During both exacerbations, chest X-ray revealed left pneumothorax.", "markdown": "### Imaging Findings\n- During both exacerbations, chest X-ray revealed left pneumothorax."}]	ORPHA:494428	pathology_micro	PMC8634063
169	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAPsA8QDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is an 81-year-old Japanese woman. ### Symptoms and Signs - She had one year of claudication and posterior thigh pain before surgery. - Eleven days after lumbar surgery, she developed acute excruciating bilateral thigh pain followed by rapidly worsening bilateral leg weakness and ...	Based on the patient's brief clinical history and the provided postoperative spine imaging and nerve conduction study, what diagnoses should be considered for this patient? Use the images to help distinguish a postoperative spinal complication from a peripheral neuropathic process.	Guillain-Barré syndrome	["acute inflammatory demyelinating polyradiculoneuropathy (AIDP)", "acute inflammatory demyelinating polyradiculoneuropathy", "Guillain-Barré syndrome"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- Before surgery, magnetic resonance imaging showed severe lumbar spinal stenosis at L1-5 and spondylolisthesis at L4/5.\n- Spinal computed tomography showed no evidence of spinal cord compression.\n- Brain MRI showed no abnormalities.\n-...	ORPHA:2103	other	PMC8337157
172	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAJQAtQDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is a 65-year-old woman. ### Medical History - The patient has rheumatoid arthritis and has been treated with methotrexate for 7 years. - She is a hepatitis B virus carrier. ### Laboratory Results - Several tumor markers were not elevated. - Liver function test results were norma...	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	Methotrexate-associated primary hepatic lymphoma (diffuse large B-cell lymphoma)	["Methotrexate-associated primary hepatic lymphoma", "MTX-associated primary hepatic lymphoma", "methotrexate-associated primary hepatic malignant lymphoma", "MTX-associated primary hepatic malignant lymphoma", "primary hepatic diffuse large B-cell lymphoma", "methotrexate-associated primary hepatic diffuse large B-cel...	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- Abdominal ultrasound detected a low echoic tumor in a medical condition segment 6 measuring 16 × 29 mm.\n- Contrast-enhanced CT showed a solitary a medical condition mass measuring 16 × 29 mm with slight enhancement in the arterial phas...	ORPHA:544;ORPHA:86904	ct	PMC5222945
173	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAGMAs4DASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is a 76-year-old male. ### Symptoms and Signs - The patient presented with a 4-week history of dry cough. - He later developed poor appetite, weight loss, and obstructive jaundice. ### Medical History - Past history included non-muscle invasive bladder cancer and sigmoid cancer....	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	IgG4-related disease	["IgG4-related disease", "IgG4-RD"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- Chest X-ray demonstrated pleural calcification and a new rounded density in the right mid-zone that was not present on previous imaging.\n- CT scan of the thorax demonstrated peripheral pulmonary consolidation and pleural thickening ove...	ORPHA:284264	ct	PMC7527011
174	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAJKAeADASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is a 69-year-old Caucasian man from northeastern Iran. ### Symptoms and Signs - He presented with a solitary lesion on the inner region of the right calf for 6 months. - The lesion enlarged rapidly during the last month and caused discomfort. ### Relevant History - There was no ...	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	Merkel cell carcinoma	["cutaneous neuroendocrine carcinoma", "primary cutaneous neuroendocrine carcinoma", "MCC"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- Ultrasound of the right groin revealed multiple lymph nodes with thick and hypervascular cortex and central and peripheral vascular flow, with the largest lymph node measuring 27 × 19 × 31 mm, strongly suggestive of malignancy.\n- A spi...	ORPHA:79140	pathology_micro	PMC8259794
175	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCATgAbYDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - The patient is a 47-year-old woman. - The patient is African American. ### Symptoms and Signs - The patient presented with a 1-year history of left nasal obstruction and intermittent epistaxis. ### Medical History - Past medical history includes hypertension, hyperlipidemia, and coronary ar...	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	Malignant peripheral nerve sheath tumor	["The primary diagnosis is an intermediate grade malignant peripheral nerve sheath tumor (MPNST) of the nasal cavity and paranasal sinus.", "MPNST", "intermediate grade malignant peripheral nerve sheath tumor of the nasal cavity and paranasal sinus", "malignant peripheral nerve sheath tumour", "malignant schwannoma of ...	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- A CT scan of the sinuses revealed a left nasal mass measuring 3.4 × 3.1 × 2.4 cm with associated thinning of the medial orbital wall, nasal septum, and medial wall of the maxillary sinus.\n- MRI at a medical condition showed a 2.1 × 1.7...	ORPHA:3148	pathology_micro	PMC6878039
176	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAJgAzIDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - 73-year-old woman. ### Symptoms and Signs - Presented over time with upper abdominal pain, decreased appetite, nausea, vomiting, headache, fatigue, polydipsia, polyuria, blurred vision, dyspnea, cough, and one syncopal episode. ### Medical History - Prior coronary artery bypass grafting abo...	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	Erdheim-Chester disease	["Erdheim-Chester disease (ECD)", "ECD"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- CT scan of the abdomen and pelvis showed an ill-defined, infiltrative low-attenuated lesion in the tail of the pancreas with surrounding fat stranding.\n- MRI of the pancreas showed an ill-defined solid lesion with high signal intensity...	ORPHA:35687	pet	PMC10006724
177	["/9j/4AAQSkZJRgABAQAAAQABAAD/2wBDAAgGBgcGBQgHBwcJCQgKDBQNDAsLDBkSEw8UHRofHh0aHBwgJC4nICIsIxwcKDcpLDAxNDQ0Hyc5PTgyPC4zNDL/2wBDAQkJCQwLDBgNDRgyIRwhMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjL/wAARCAHoAVQDASIAAhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQAAAF9AQIDAAQRBR...	### Patient Demographics - Two term neonates (one female, one male). ### Symptoms and Signs - Both neonates had severe respiratory distress and cyanosis at birth. ### Medical History - There was no known parental consanguinity or family history of congenital malformations. - Antenatal ultrasound showed polyhydramnios...	Based on the patient's brief clinical history and the provided medical images, what diagnoses should be considered for this patient?	Thanatophoric dysplasia type 1	["thanatophoric dysplasia type 1", "TD type 1", "thanatophoric dwarfism type 1", "type 1 thanatophoric dysplasia", "thanatophoric skeletal dysplasia type 1"]	[{"phase": "mechanical_pre_model_feedback", "title": "Imaging Findings", "body": "- Radiological findings for baby 1 included macrocephaly with craniofacial disproportion, narrow chest with flattened ribs, poorly aerated lung fields, shortening of the long bones with telephone-handle appearance of the humerus and femur...	ORPHA:2655	xray	PMC9534681

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